Here are what the editors at HealthDay consider to be the most important developments in Gastroenterology for December 2010. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Treatment Effective for HCC Patients With Cirrhosis
THURSDAY, Dec. 30 (HealthDay News) -- Radiofrequency ablation (RFA) appears to be safe and effective for the treatment of hepatocellular carcinoma (HCC) among patients with cirrhosis, according to a study published online Oct. 21 in Hepatology.
Mutation May Increase GI Cancer Susceptibility
THURSDAY, Dec. 30 (HealthDay News) -- A single mutation in the BUB1B gene appears to result in greater susceptibility to recessively inherited gastrointestinal cancers, according to research published in the Dec. 30 issue of the New England Journal of Medicine.
Doubt Cast on Need for Some Esophageal Cancer Screening
TUESDAY, Dec. 28 (HealthDay News) -- Screening for esophageal adenocarcinoma (EAC) is not warranted in younger white men with gastroesophageal reflux disease (GERD) or white women of any age with GERD symptoms, according to research published online Dec. 7 in the American Journal of Gastroenterology.
Choledocholithiasis Pain Tied to Increasing Transaminases
THURSDAY, Dec. 23 (HealthDay News) -- In patients with acute symptomatic choledocholithiasis, increasing duration of pain is associated with increasing liver function tests (LFTs), especially transaminases, according to research published in the December issue of Clinical Gastroenterology and Hepatology.
Immunochemical Fecal Testing Speeds Cancer Detection
THURSDAY, Dec. 23 (HealthDay News) -- Patients at high risk for colorectal cancer who undergo yearly fecal immunochemical tests (FITs) along with scheduled colonoscopies are likely to have neoplasia detected a median of 25 months earlier than colonoscopy alone, according to a study published in the December issue of Gastroenterology.
Racial Disparities in HCC Exist Regardless of Treatment
THURSDAY, Dec. 23 (HealthDay News) -- Blacks have a higher rate of mortality than whites, Hispanics, and Asians after treatment for early-stage hepatocellular carcinoma (HCC), and this disparity persists even after adjusting for various types of treatment and treatment benefit, according to research published in the December issue of the Archives of Surgery.
Placebos Without Deception Still Work in IBS
THURSDAY, Dec. 23 (HealthDay News) -- The placebo effect appears to work in some irritable bowel syndrome (IBS) patients even when they know their treatment contains nothing more than an inert substance, according to research published online Dec. 22 in PLoS ONE.
Rotavirus Vaccine Linked to Consistent Effect in Children
THURSDAY, Dec. 23 (HealthDay News) -- The drop in pediatric hospitalizations linked to diarrhea and rotavirus that was seen in the 2007 to 2008 season, compared to prevaccine seasons, was sustained but smaller in the 2008 to 2009 season, according to research published online Dec. 20 in Pediatrics.
High Abdominal Adipose Tissue Volume Ups Erosive Esophagitis
WEDNESDAY, Dec. 22 (HealthDay News) -- Visceral abdominal adipose tissue volume of 500 cm³ or above in both men and women doubles the risk of erosive esophagitis, according to a study in the December issue of Gastroenterology.
Cowden Syndrome Tied to Colon Cancer Risk
TUESDAY, Dec. 21 (HealthDay News) -- Individuals who carry the genetic mutation that causes Cowden syndrome -- associated with macrocephaly and an elevated risk of breast and thyroid cancers -- are also at increased risk of colon cancer, according to a study published in the December issue of Gastroenterology.
PPIs Found to Ameliorate Postnasal Drainage Symptoms
TUESDAY, Dec. 21 (HealthDay News) -- Symptoms associated with chronic postnasal drainage are improved by lansoprazole, according to a study published in the December issue of Gastroenterology.
High Levels of Arachidonic Acid Linked to Ulcerative Colitis
TUESDAY, Dec. 21 (HealthDay News) -- High levels of the dietary n-6 polyunsaturated fatty acid known as arachidonic acid are associated with an increased risk of developing ulcerative colitis, according to a report published in the December issue of Gastroenterology.
Acid-Suppressive Drugs May Up Pneumonia Risk
TUESDAY, Dec. 21 (HealthDay News) -- The use of a proton pump inhibitor or histamine2 receptor antagonist may be associated with an elevated risk of community- and hospital-acquired pneumonia, according to a study published online Dec. 20 in CMAJ, the journal of the Canadian Medical Association.
Colorectal Screening Reminders May Be Useful
FRIDAY, Dec. 17 (HealthDay News) -- The use of colorectal cancer screening reminders may be effective in getting people to be screened, according to research published online Dec. 13 in the Archives of Internal Medicine.
Research Supports Bleeding Prophylaxis in Biliary Atresia
FRIDAY, Dec. 17 (HealthDay News) -- Children with biliary atresia are at increased risk of portal hypertension early in life, and primary prophylaxis of bleeding is important in those with esophageal varices and red markings and/or gastric varices along the cardia, according to a report published in the December issue of Gastroenterology.
Novel Tool Predicts Crohn's Disease Risks
FRIDAY, Dec. 17 (HealthDay News) -- Researchers have developed a tool that can be used to predict complications of Crohn's disease (CD) and suggest a likely response to treatment; their research has been published in the January issue of Inflammatory Bowel Diseases.
48 Million Americans Acquire Foodborne Illnesses Annually
THURSDAY, Dec. 16 (HealthDay News) -- Approximately 48 million Americans acquire foodborne illnesses annually, with 128,000 becoming hospitalized and 3,000 dying each year as a result of the diseases, according to new estimates from the U.S. Centers for Disease Control and Prevention, published online Dec. 15 in Emerging Infectious Diseases.
Fat Index Associated With Liver Damage in Hep C Patients
THURSDAY, Dec. 9 (HealthDay News) -- The visceral adiposity index (VAI), a score that combines body mass index, waist circumference, triglycerides, and high-density lipoprotein levels, is associated with liver damage and viral load in patients with genotype 1 chronic hepatitis C (G1 CHC), according to a study in the November issue of Hepatology.
Combining Statins and Fibrates Increases Rhabdomyolysis Risk
THURSDAY, Dec. 9 (HealthDay News) -- Patients who are newly treated with statin-fibrate concurrent therapy are slightly more likely to be hospitalized with rhabdomyolysis than those who take just one of the medications, according to research published in the Dec. 1 issue of The American Journal of Cardiology.
Low-Dose Aspirin May Not Hamper Fecal Blood Testing
TUESDAY, Dec. 7 (HealthDay News) -- Among people screened with immunochemical fecal occult blood tests (iFOBTs), the tests may have higher sensitivity for detecting advanced colorectal neoplasms in those using low-dose aspirin, according to research published in the Dec. 8 issue of the Journal of the American Medical Association.
High Stress of Crohn's Disease Associated With Flare-Ups
THURSDAY, Dec. 2 (HealthDay News) -- Posttraumatic stress disorder (PTSD) associated with the burden of having Crohn's disease appears to be linked to disease exacerbations, according to a study published online Dec. 1 in Frontline Gastroenterology.
Burnout Driving Away Many Emergency Physicians
THURSDAY, Dec. 2 (HealthDay News) -- Conflicts between work and family and poor on-the-job teamwork contribute to burnout and drive many physicians, particularly emergency physicians, to want to leave their profession, according to a study published online Dec. 1 in the Emergency Medicine Journal.
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