Here are what the editors at HealthDay consider to be the most important developments in Infectious Disease for December 2010. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Deer-Associated Parapoxvirus Infection Identified
THURSDAY, Dec. 30 (HealthDay News) -- Parapoxvirus infections were identified in two deer hunters in 2009 and, with deer populations on the rise, the potential for deer-associated parapoxvirus infections may also be increasing, according to a report published in the Dec. 30 issue of the New England Journal of Medicine.
ROI Production Tied to Survival in Granulomatous Disease
WEDNESDAY, Dec. 29 (HealthDay News) -- Disease severity and survival in patients with chronic granulomatous disease appear to be linked to the degree of residual reactive oxygen intermediate (ROI) production, which can be determined at diagnosis and used to guide treatment choices, according to research published in the Dec. 30 issue of the New England Journal of Medicine.
Expanded Screening, Treatment Could Reduce New HIV Infections
THURSDAY, Dec. 23 (HealthDay News) -- Expanding screening and treatment for HIV would likely reduce the rate of new infections, especially if combined with interventions that result in less risky behavior, according to research published in the Dec. 21 issue of the Annals of Internal Medicine.
Rotavirus Vaccine Linked to Consistent Effect in Children
THURSDAY, Dec. 23 (HealthDay News) -- The drop in pediatric hospitalizations linked to diarrhea and rotavirus that was seen in the 2007 to 2008 season, compared to prevaccine seasons, was sustained but smaller in the 2008 to 2009 season, according to research published online Dec. 20 in Pediatrics.
Adjuvanted H1N1 Vaccine May Beat Whole-Virion Vaccine
MONDAY, Dec. 20 (HealthDay News) -- An adjuvanted split-virus vaccine appears to provide a more rapid and stronger immune response against pandemic influenza A H1N1 compared to a whole-virion vaccine, according to a study published online Dec. 17 in The Lancet Infectious Diseases.
Adherence to Schedule for HPV Vaccination Series Low
FRIDAY, Dec. 17 (HealthDay News) -- Adherence to recommended schedules for human papillomavirus (HPV) quadrivalent vaccine is relatively low, and even lower among blacks, raising concerns about disease disparity, according to research published online Dec. 13 in Pediatrics.
Report Addresses Vaccination Disparities in Older Adults
THURSDAY, Dec. 16 (HealthDay News) -- Older African-Americans and Hispanics are much less likely than older whites to get vaccinated against influenza and pneumonia, according to a report by the American Lung Association, "Missed Opportunities: Influenza and Pneumonia Vaccination in Older Adults."
48 Million Americans Acquire Foodborne Illnesses Annually
THURSDAY, Dec. 16 (HealthDay News) -- Approximately 48 million Americans acquire foodborne illnesses annually, with 128,000 becoming hospitalized and 3,000 dying each year as a result of the diseases, according to new estimates from the U.S. Centers for Disease Control and Prevention, published online Dec. 15 in Emerging Infectious Diseases.
2009 H1N1 Vaccine Effective and Safe in Beijing
WEDNESDAY, Dec. 15 (HealthDay News) -- The PANFLU.1 vaccine, a monovalent split-virion vaccine of 15 µg of hemagglutinin antigen without adjuvant, appears to be safe and effective against H1N1 virus infection in school-age children in Beijing, according to a study published in the Dec. 16 issue of the New England Journal of Medicine.
Articles Detail Drug Resistance Issues in H1N1 Influenza
TUESDAY, Dec. 14 (HealthDay News) -- The detection of seasonal influenza A(H1N1) viruses that are resistant to oseltamivir and adamantanes is a cause for concern, and an outbreak of oseltamivir-resistant pandemic influenza A(H1N1) 2009 virus occurred in the United Kingdom in late 2009, according to two articles published in the Jan. 1 issue of The Journal of Infectious Diseases.
Incidence of Neonatal Herpes Varies by Region, Insurance
TUESDAY, Dec. 14 (HealthDay News) -- Neonatal herpes simplex virus (nHSV) is relatively rare, but more common among Midwestern newborns and those covered by public health insurance, according to research published online Dec. 13 in Pediatrics.
CVB1 Is Predominant Enterovirus Serotype Detected
MONDAY, Dec. 13 (HealthDay News) -- In 2007 and 2008, coxsackievirus B1 (CVB1) was the predominant enterovirus serotype detected, with states in the South reporting the most serotyped enterovirus detections, according to research published in the Dec. 10 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.
In Developing Nations, Health-Care-Related Infections High
FRIDAY, Dec. 10 (HealthDay News) -- Developing countries experience a much higher burden of health-care-associated infection than do high-income nations, according to a meta-analysis published online Dec. 10 in The Lancet.
Fat Index Associated With Liver Damage in Hep C Patients
THURSDAY, Dec. 9 (HealthDay News) -- The visceral adiposity index (VAI), a score that combines body mass index, waist circumference, triglycerides, and high-density lipoprotein levels, is associated with liver damage and viral load in patients with genotype 1 chronic hepatitis C (G1 CHC), according to a study in the November issue of Hepatology.
Children in Group Care Early See Infection Rates Drop Later
THURSDAY, Dec. 9 (HealthDay News) -- Children who attend group child care (GCC) in their early preschool years have higher respiratory and ear infection rates in those years than children cared for at home, but by school age they have lower infection rates, according to a study in the December issue of the Archives of Pediatrics & Adolescent Medicine.
Secondhand Smoke Tied to Invasive Bacterial Disease
WEDNESDAY, Dec. 8 (HealthDay News) -- Exposure to secondhand smoke (SHS) appears to be associated with the risk for invasive meningococcal disease, according to research published online Dec. 7 in PLoS Medicine.
Reimbursement Issues Hinder Combination Vaccine Uptake
MONDAY, Dec. 6 (HealthDay News) -- Inadequate reimbursement for combination vaccines prevents more than 20 percent of pediatricians from using them, with practice size and proportion of children whose vaccinations are paid for with public funds also influencing use of combination vaccines, according to research published in the December issue of the Archives of Pediatrics & Adolescent Medicine.
CDC: Flu Outbreak in Georgia Signifies Start of Flu Season
MONDAY, Dec. 6 (HealthDay News) -- Georgia appears to be experiencing an influenza outbreak, mostly among school-aged children and caused by the influenza B strain, which can be well controlled with this season's influenza vaccine, according to a Dec. 3 press briefing by the U.S. Centers for Disease Control and Prevention.
Long-Term Toxoplasmosis Outcomes Generally Good
THURSDAY, Dec. 2 (HealthDay News) -- In children with toxoplasmosis diagnosed and treated in utero, about a quarter will develop chorioretinitis -- almost all before age 5 -- and outcomes are consistently good, according to research published in the December issue of the American Journal of Obstetrics & Gynecology.
Burnout Driving Away Many Emergency Physicians
THURSDAY, Dec. 2 (HealthDay News) -- Conflicts between work and family and poor on-the-job teamwork contribute to burnout and drive many physicians, particularly emergency physicians, to want to leave their profession, according to a study published online Dec. 1 in the Emergency Medicine Journal.
Bloodstream Infections Tied to Excess Mortality in ICU
WEDNESDAY, Dec. 1 (HealthDay News) -- Health-care-associated bloodstream infections and pneumonia appear to be strongly associated with increased mortality among patients admitted to intensive care units (ICUs), according to a study published online Dec. 1 in The Lancet Infectious Diseases.
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