Here are what the editors at HealthDay consider to be the most important developments in Neurology for December 2010. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Racial, Ethnic Differences in Multiple Sclerosis Identified
THURSDAY, Dec. 30 (HealthDay News) -- Caucasians, Latinos, and African-Americans with multiple sclerosis (MS) appear to have differing experiences with symptoms, treatments, and other factors related to their disease, according to research published in the Autumn issue of Ethnicity & Disease.
No Improvement Seen in Very Premature Infants
WEDNESDAY, Dec. 29 (HealthDay News) -- Although postnatal steroid exposure has fallen in recent years for babies born before 25 weeks' gestation, survival rates and adverse neurosensory and cognitive outcomes have changed little, according to research published online Dec. 27 in Pediatrics.
Social Engagement Targets May Help in Autism Intervention
WEDNESDAY, Dec. 29 (HealthDay News) -- In toddlers with autism spectrum disorders (ASD), the addition of social engagement targets to interventions may improve social and communication skills, according to a study in the January issue of the Journal of Child Psychology and Psychiatry.
Prepregnancy Overweight May Not Lead to Behavior Issues
WEDNESDAY, Dec. 29 (HealthDay News) -- Being overweight prior to pregnancy may not increase the offspring's risk of behavioral problems or cognitive issues, according to a study published online Dec. 27 in Pediatrics.
One in 26 Americans Will Develop Epilepsy
TUESDAY, Dec. 28 (HealthDay News) -- About 12 million Americans will develop epilepsy in their lifetime, and lifetime risk approximately doubles from age 50 to age 80, according to research published in the Jan. 4 issue of Neurology.
Fish Consumption Differences May Affect Stroke Disparities
THURSDAY, Dec. 23 (HealthDay News) -- The amount of fish consumed, and preferences for preparation (i.e., fried versus nonfried), vary regionally and by race and may be a factor behind disparities in stroke, according to research published online Dec. 22 in Neurology.
Childhood-Onset Epilepsy Tied to Much Higher Death Risk
THURSDAY, Dec. 23 (HealthDay News) -- Childhood-onset epilepsy is associated with a substantially increased risk of epilepsy-related death, including sudden, unexplained death, especially among those not in five-year terminal remission, according to a study published in the Dec. 23 issue of the New England Journal of Medicine.
Withholding of Thrombolytic Treatment Not Justified
WEDNESDAY, Dec. 22 (HealthDay News) -- Outcomes for patients with diabetes or history of stroke who receive thrombolytic therapy for a new ischemic stroke are better than outcomes for those who do not receive thrombolytic therapy, according to a report in the December issue of Diabetes Care.
Stroke and Left Septal Pouch Not Associated
MONDAY, Dec. 20 (HealthDay News) -- Although some have suggested the presence of a left septal pouch (LSP) may lead to thromboembolic complications, current research finds no association between LSPs and stroke; the study results have been published in the December issue of the Journal of the American College of Cardiology: Cardiovascular Imaging.
Race, Economics Linked to Parkinsonism Outcomes
MONDAY, Dec. 20 (HealthDay News) -- Race and socioeconomic status appear to influence disease severity related to parkinsonism in patients treated at a tertiary Movement Disorders Center, according to research published online Dec. 13 in the Archives of Neurology.
Study Investigates Genetics of Pediatric Medulloblastomas
MONDAY, Dec. 20 (HealthDay News) -- Childhood medulloblastomas may have a smaller number of gene alterations than the number seen in adult solid tumors, according to research published online Dec. 16 in Science.
Death, Readmission Likely for Medicare Stroke Patients
FRIDAY, Dec. 17 (HealthDay News) -- Most Medicare beneficiaries discharged from the hospital after ischemic stroke either die or are rehospitalized within one year, according to a study published online Dec. 16 in Stroke.
Single Brain Death Examination Likely Sufficient
THURSDAY, Dec. 16 (HealthDay News) -- A second clinical examination to determine brain death may not be necessary and could result in a loss of viable organs for donation, according to research published online Dec. 15 in Neurology.
Statistics Update Finds CVD, Stroke Death Rates Declining
THURSDAY, Dec. 16 (HealthDay News) -- Death rates from cardiovascular disease (CVD) and stroke fell in a recent period, but inpatient cardiovascular procedures rose at the same time and costs exerted a sizable burden compared to other conditions, according to updated statistics published online Dec. 15 in Circulation.
HDL Linked to Lower Risk of Alzheimer's Disease
WEDNESDAY, Dec. 15 (HealthDay News) -- Older adults with high levels of high-density lipoprotein cholesterol (HDL-C) may have a lower risk of Alzheimer's disease (AD), according to research published in the December issue of the Archives of Neurology.
Many With Brain Tumors Use Alternative Therapies
TUESDAY, Dec. 14 (HealthDay News) -- Many individuals with glial tumors use alternative therapies in combination with standard treatments, according to a study published in the Dec. 14 issue of Neurology.
Racial Disparity Seen in Pediatric-Onset MS Patients
MONDAY, Dec. 13 (HealthDay News) -- African-American children with pediatric-onset multiple sclerosis (POMS) may experience greater impairment of certain cognitive functions than their Caucasian peers, according to research published in the Dec. 7 issue of Neurology.
Death Rate in U.S. Down, but So Is Life Expectancy, Slightly
THURSDAY, Dec. 9 (HealthDay News) -- Life expectancy has declined slightly in the United States, stroke is no longer the third leading cause of death, and heart disease and cancer still account for nearly half of U.S. deaths; these and other statistics can be found in a new report from the U.S. Centers for Disease Control and Prevention, entitled "Deaths: Preliminary Data for 2008."
Huntington's Biomarkers Predict Progression Early
FRIDAY, Dec. 3 (HealthDay News) -- New biomarkers for Huntington's disease (HD) may serve as useful targets in future trials evaluating disease-modifying treatments to track progression of patients with premanifest and early HD, according to a study published online Dec. 2 in The Lancet Neurology.
Spina Bifida Is Only Major Risk to Fetus From Carbamazepine
FRIDAY, Dec. 3 (HealthDay News) -- Spina bifida is the only major congenital malformation significantly associated with exposure to carbamazepine monotherapy, and this risk is much lower than the risk of spina bifida associated with use of valproic acid, according to research published Dec. 2 in BMJ.
NO Key in Modulating Amyloid Precursor Protein Expression
FRIDAY, Dec. 3 (HealthDay News) -- Nitric oxide (NO) appears to have an important role in modulating expression and processing of amyloid precursor protein (APP), according to research published online Dec. 2 in Circulation Research.
Updated Guidelines for the Prevention of Stroke Issued
FRIDAY, Dec. 3 (HealthDay News) -- The American Heart Association/American Stroke Association has released new guidelines for the primary prevention of strokes. The guidelines have been published online Dec. 2 in Stroke.
Chronic Pesticide Exposure Tied to Cognitive Decline
THURSDAY, Dec. 2 (HealthDay News) -- Chronic pesticide exposure appears to be associated with an increased risk of long-term cognitive decline and possibly evolution toward dementia, according to a study published online Nov. 22 in Occupational and Environmental Medicine.
Diabetes Alters Brain Cholesterol Metabolism in Mice
THURSDAY, Dec. 2 (HealthDay News) -- Diabetes and insulin can alter brain cholesterol metabolism, a fact that may play a key role in the neurologic and metabolic dysfunction in diabetes patients, according to a mouse study published in the Dec. 1 issue of Cell Metabolism.
Burnout Driving Away Many Emergency Physicians
THURSDAY, Dec. 2 (HealthDay News) -- Conflicts between work and family and poor on-the-job teamwork contribute to burnout and drive many physicians, particularly emergency physicians, to want to leave their profession, according to a study published online Dec. 1 in the Emergency Medicine Journal.
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