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Category: Gynecology | Monthly Briefing

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December 2010 Briefing - OBGYN & Women’s Health

Last Updated: January 03, 2011.

 

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Here are what the editors at HealthDay consider to be the most important developments in OBGYN & Women's Health for December 2010. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Gestational Diabetes Testing Guidelines Updated

THURSDAY, Dec. 30 (HealthDay News) -- In an effort to increase the identification of women with gestational diabetes and reduce health risks to mother and fetus, the American Diabetes Association (ADA) has adopted new guidelines for testing pregnant women for gestational diabetes; these guidelines have been published in a special supplement to the January issue of Diabetes Care.

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Pad Test Correlates With Subjective Leakage Assessment

WEDNESDAY, Dec. 29 (HealthDay News) -- There is concordance between the one-hour pad test and subjective assessment of stress urinary incontinence, according to research published in the December issue of Urology.

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Prepregnancy Overweight May Not Lead to Behavior Issues

WEDNESDAY, Dec. 29 (HealthDay News) -- Being overweight prior to pregnancy may not increase the offspring's risk of behavioral problems or cognitive issues, according to a study published online Dec. 27 in Pediatrics.

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Polycystic Ovary Syndrome Tied to Diabetes, Dyslipidemia

TUESDAY, Dec. 28 (HealthDay News) -- Women with polycystic ovary syndrome (PCOS) appear to be at a higher risk of diabetes and dyslipidemia, independent of body mass index (BMI), according to a study published in the January issue of Obstetrics & Gynecology.

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Fertility in Rheumatic Disease Patients Needs Priority

TUESDAY, Dec. 28 (HealthDay News) -- Reduced fertility is not uncommon in both male and female patients being treated for rheumatic diseases; therefore, family planning should be discussed with all patients requiring therapy with drugs that may impair fertility, according to a review published in the December issue of Arthritis Care & Research.

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Maternal Vitamin D Levels Tied to Infant Respiratory Health

TUESDAY, Dec. 28 (HealthDay News) -- Infants with higher cord-blood levels of 25-hydroxyvitamin D (25[OH]D) appear to have a lower risk for respiratory infection and wheezing, but 25(OH)D levels do not appear to have an association with asthma, according to research published online Dec. 27 in Pediatrics.

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Contraceptives Linked to Higher Glucose, Insulin Levels

TUESDAY, Dec. 28 (HealthDay News) -- The use of depot medroxyprogesterone acetate appears to be associated with slightly higher levels of fasting glucose and insulin, according to a study in the January issue of Obstetrics & Gynecology.

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FullPIERS Model Predicts Preeclampsia Adverse Events

MONDAY, Dec. 27 (HealthDay News) -- A new model, called the fullPIERS model, may help identify women at risk for adverse maternal outcomes associated with preeclampsia up to seven days prior to complication onset, according to a study published online Dec. 25 in The Lancet.

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Fetal Antiretroviral Exposure Impacts Cardiac Development

THURSDAY, Dec. 23 (HealthDay News) -- Fetal exposure to antiretroviral therapy (ART) appears to be associated with increased left ventricular (LV) fractional shortening and contractility as well as reduced LV mass, septal thickness, and LV dimension, especially in girls, according to a study published in the Jan. 4 issue of the Journal of the American College of Cardiology.

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Single Embryo Transfer Ups Chance of Term Birth

WEDNESDAY, Dec. 22 (HealthDay News) -- Single embryo transfers result in fewer pregnancies than double embryo transfers, but the former approach substantially raises the chances of a term singleton birth, according to research published Dec. 21 in BMJ.

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Prenatal Micronutrients Tied to Increased Functioning

TUESDAY, Dec. 21 (HealthDay News) -- In areas where the community diet may be lacking in iron, prenatal supplementation with iron and folic acid is associated with increased intellectual and motor functioning in offspring, according to research published in the Dec. 22/29 issue of the Journal of the American Medical Association.

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CDC: Birth Rates in 2009 at Record Lows

TUESDAY, Dec. 21 (HealthDay News) -- The birth rate among women in their twenties and thirties, preterm birth rate, percentage of births to teenagers, general fertility rate, and total number of births declined in 2009, with the birth rate among women in their forties and the cesarean delivery rate increasing, according to a report from the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics.

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Fat Distribution Tied to Higher Risk of ER-Negative Cancer

FRIDAY, Dec. 17 (HealthDay News) -- Abdominal adiposity does not appear to play a significant role in the risk for premenopausal breast cancer overall, though it does seem to be associated with an increased risk of estrogen receptor (ER)-negative cancer, according to research published online Dec. 16 in the Journal of the National Cancer Institute.

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Decreasing Depression Tied to Longer Survival in Breast CA

FRIDAY, Dec. 17 (HealthDay News) -- Researchers studying women with metastatic breast cancer (MBC) have found a correlation between a reduction in depressive symptoms and increased duration of survival; their findings have been published online Dec. 13 in the Journal of Clinical Oncology.

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Early Cell Phone Exposure Linked to Behavioral Problems

THURSDAY, Dec. 16 (HealthDay News) -- Early (i.e., prenatal and postnatal) cell phone exposure may set children up for subsequent behavioral problems, according to research published online Dec. 7 in the Journal of Epidemiology and Community Health.

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Two More Placental miRNAs May Be Tied to Preeclampsia

THURSDAY, Dec. 16 (HealthDay News) -- Differences in the expression of eight placental micro RNAs (miRNA) may contribute to the development of preeclampsia, according to a study published online Nov. 22 in the American Journal of Obstetrics & Gynecology.

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Maternal Age Over 45 Linked to Higher Maternal and Fetal Risk

WEDNESDAY, Dec. 15 (HealthDay News) -- Pregnancy at extreme advanced maternal age is associated with increased maternal and fetal risk, according to research published in the December issue of the American Journal of Obstetrics & Gynecology.

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Maternal Depression Tied to Offspring Stress

WEDNESDAY, Dec. 15 (HealthDay News) -- An elevated level of depressive symptoms among women during pregnancy appears to be associated with higher levels of stress hormones among offspring at birth, as well as other neurological and behavioral differences in offspring, according to a study published online Oct. 29 in Infant Behavior and Development.

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Transvaginal Ultrasound Detects Endometrial Cancer

MONDAY, Dec. 13 (HealthDay News) -- Transvaginal ultrasound (TVS) screening appears to be effective in detecting endometrial cancer prior to symptom onset in postmenopausal women, according to a study published online Dec. 13 in The Lancet Oncology.

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Annual Screening for Ovarian Cancer Likely Not Helpful

MONDAY, Dec. 13 (HealthDay News) -- Widespread screening for ovarian cancer likely would result in no more than a slight reduction in mortality, even when basing estimates on a model that incorporates two cancer phenotypes, according to research published online Dec. 13 in Cancer.

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Brachytherapy Increasing After Breast-Conserving Surgery

FRIDAY, Dec. 10 (HealthDay News) -- Nonclinical factors, including health policy decisions, appear to play an important role in the increasing use of partial breast irradiation with brachytherapy after breast-conserving surgery (BCS), according to research published online Dec. 6 in the Journal of Clinical Oncology.

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Resistance Exercise Improves Sugar Levels in Gestational DM

FRIDAY, Dec. 10 (HealthDay News) -- Women with gestational diabetes mellitus (GDM) who perform resistance exercises during pregnancy may have better capillary glycemic levels and be less likely to require insulin coverage, according to a study in the December issue of the American Journal of Obstetrics & Gynecology.

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U.S. Falling Short on Women's Health Goals

FRIDAY, Dec. 10 (HealthDay News) -- In terms of women's health, the United States hasn't met a number of its goals, many of which are found on the Healthy People 2010 list, according to a new report from the National Women's Law Center and the Oregon Health & Science University.

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Depression Tied to Decreased Gestational Age, Birth Weight

THURSDAY, Dec. 9 (HealthDay News) -- Pregnant women with depressive symptoms may give birth earlier and to lower-birth-weight offspring than those without depressive symptoms, according to a study published in the December issue of the American Journal of Obstetrics & Gynecology.

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In Pregnancy, Buprenorphine Effective for Opioid Dependency

WEDNESDAY, Dec. 8 (HealthDay News) -- Buprenorphine is an acceptable alternative to methadone for the treatment of opioid dependency during pregnancy that appears to reduce the severity of neonatal abstinence syndrome (NAS), according to a study published in the Dec. 9 issue of the New England Journal of Medicine.

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Restless Legs During Pregnancy Ups Risk of Chronic Form

WEDNESDAY, Dec. 8 (HealthDay News) -- Transient restless legs syndrome (RLS) during pregnancy is a significant risk factor for future chronic idiopathic RLS, according to research published in the Dec. 7 issue of Neurology.

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Nausea, Vomiting in Pregnancy Decrease With Diclectin

WEDNESDAY, Dec. 8 (HealthDay News) -- A delayed-release formulation of doxylamine succinate and pyridoxine hydrochloride can help lessen symptoms of nausea and vomiting in pregnancy, according to a study published in the December issue of the American Journal of Obstetrics & Gynecology.

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Benefits of Radiotherapy in Breast Cancer Confirmed

WEDNESDAY, Dec. 8 (HealthDay News) -- A long-term follow-up study has confirmed the effectiveness of radiotherapy in reducing the incidence of ipsilateral breast events and found that tamoxifen has a role in preventing local and contralateral new breast events for women with ductal carcinoma in situ (DCIS). The research has been published online Dec. 8 in The Lancet Oncology.

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ECGs May Miss Heart Disease in Postmenopausal Women

MONDAY, Dec. 6 (HealthDay News) -- Postmenopausal women may not be able to rule out coronary heart disease (CHD) based on a normal electrocardiogram (ECG), according to research published in the Dec. 1 issue of The American Journal of Cardiology.

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Primary Ovarian Insufficiency Tied to Depression Risk

MONDAY, Dec. 6 (HealthDay News) -- Women with primary ovarian insufficiency (POI) appear to be at an increased lifetime risk for major depression, according to a study published online Nov. 3 in the Journal of Clinical Endocrinology & Metabolism.

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Factors Appear Useful in Predicting Gestational Diabetes

FRIDAY, Dec. 3 (HealthDay News) -- Several easily measured demographic and clinical factors, along with two biochemical values, can be used for predicting gestational diabetes mellitus (GDM) in women in their first trimester of pregnancy, according to research published in the December issue of Diabetes.

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Spina Bifida Is Only Major Risk to Fetus From Carbamazepine

FRIDAY, Dec. 3 (HealthDay News) -- Spina bifida is the only major congenital malformation significantly associated with exposure to carbamazepine monotherapy, and this risk is much lower than the risk of spina bifida associated with use of valproic acid, according to research published Dec. 2 in BMJ.

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Sexual Function Same in OCP, Injectable Progestin Users

FRIDAY, Dec. 3 (HealthDay News) -- Users of combined oral contraceptives (COC) and depot medroxyprogesterone acetate (DMPA) have significantly different sex hormone levels, but no differences in sexual function, according to research published in the December issue of the American Journal of Obstetrics & Gynecology.

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Oral Progestogens Found Inferior in Endometrial Hyperplasia

FRIDAY, Dec. 3 (HealthDay News) -- Oral progestogens may result in a lower endometrial hyperplasia regression rate than the levonorgestrel-releasing intrauterine system (LNG-IUS), according to a literature review and analysis published in the December issue of the American Journal of Obstetrics & Gynecology.

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Socioeconomic Differences in Neonatal Deaths Evaluated

FRIDAY, Dec. 3 (HealthDay News) -- Most of the "deprivation gap" in neonatal mortality in England is due to differences in death rates from prematurity or congenital anomalies, according to research published online Dec. 2 in BMJ.

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Annual Cytology Best Screening Strategy After CIN

THURSDAY, Dec. 2 (HealthDay News) -- Using a model to compare various follow-up strategies after treatment for high-grade cervical intraepithelial neoplasia (CIN), annual cytology screening appears to be the most cost-effective, and human papillomavirus screening adds little value, according to research published in the November issue of Obstetrics & Gynecology.

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Mental Health Conditions Prevalent in Young Women

THURSDAY, Dec. 2 (HealthDay News) -- Depression or other serious psychological distress (SPD) is present in a substantial proportion of women of reproductive age, and a large proportion of these women go untreated, according to research published in the December issue of the American Journal of Obstetrics & Gynecology.

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Repeated Miscarriage Spikes Heart Attack Risk

THURSDAY, Dec. 2 (HealthDay News) -- Women who have had more than three miscarriages have nearly nine times greater risk of having a myocardial infarction (MI) later in life than women who have not had a miscarriage, according to a study published online Dec. 1 in Heart.

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Long-Term Toxoplasmosis Outcomes Generally Good

THURSDAY, Dec. 2 (HealthDay News) -- In children with toxoplasmosis diagnosed and treated in utero, about a quarter will develop chorioretinitis -- almost all before age 5 -- and outcomes are consistently good, according to research published in the December issue of the American Journal of Obstetrics & Gynecology.

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Burnout Driving Away Many Emergency Physicians

THURSDAY, Dec. 2 (HealthDay News) -- Conflicts between work and family and poor on-the-job teamwork contribute to burnout and drive many physicians, particularly emergency physicians, to want to leave their profession, according to a study published online Dec. 1 in the Emergency Medicine Journal.

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Docetaxel Regimen Superior in Node-Negative Breast Cancer

WEDNESDAY, Dec. 1 (HealthDay News) -- The taxane drug docetaxel, known to be superior to fluorouracil when given with doxorubicin and cyclophosphamide (TAC and FAC) for node-positive breast cancer, is also superior when used in this combination for high-risk, node-negative breast cancer, according to research published in the Dec. 2 issue of the New England Journal of Medicine.

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CDC: HIV Testing Among Adults Increasing

WEDNESDAY, Dec. 1 (HealthDay News) -- The number of adults ever tested for HIV is increasing, though nearly one-third of diagnoses still occur during late stages of disease, according to a report published in the Nov. 30 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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