December 2010 Briefing - PulmonologyLast Updated: January 03, 2011.
Here are what the editors at HealthDay consider to be the most important developments in Pulmonology for December 2010. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Nasal Congestion May Point to More Severe Asthma
WEDNESDAY, Dec. 29 (HealthDay News) -- Nasal congestion may be a sign of severe asthma, according to a study published online Nov. 26 in Respiratory Research.
Maternal Vitamin D Levels Tied to Infant Respiratory Health
TUESDAY, Dec. 28 (HealthDay News) -- Infants with higher cord-blood levels of 25-hydroxyvitamin D (25[OH]D) appear to have a lower risk for respiratory infection and wheezing, but 25(OH)D levels do not appear to have an association with asthma, according to research published online Dec. 27 in Pediatrics.
Apixaban May Beat Enoxaparin After Hip Replacement
WEDNESDAY, Dec. 22 (HealthDay News) -- In patients undergoing hip replacement, thromboprophylaxis with apixaban, an orally active, specific factor Xa inhibitor, is associated with lower rates of venous thromboembolism than enoxaparin, according to a study published in the Dec. 23 issue of the New England Journal of Medicine.
Corticosteroid Use May Increase Risk of Diabetes
TUESDAY, Dec. 21 (HealthDay News) -- The use of inhaled corticosteroids among patients with respiratory disease appears to be associated with modest increases in the risk of diabetes onset and progression, according to a study published in the November issue of The American Journal of Medicine.
Acid-Suppressive Drugs May Up Pneumonia Risk
TUESDAY, Dec. 21 (HealthDay News) -- The use of a proton pump inhibitor or histamine2 receptor antagonist may be associated with an elevated risk of community- and hospital-acquired pneumonia, according to a study published online Dec. 20 in CMAJ, the journal of the Canadian Medical Association.
Rash After Cetuximab Is Indicator of Clinical Benefit
MONDAY, Dec. 20 (HealthDay News) -- An acne-like rash among patients with non-small-cell lung cancer (NSCLC) undergoing treatment with cisplatin and vinorelbine plus cetuximab is associated with improved outcomes, according to research published online Dec. 20 in The Lancet Oncology.
Novel Agent Benefits Cystic Fibrosis Patients
MONDAY, Dec. 20 (HealthDay News) -- Denufosol, an ion channel regulator, may improve lung function in cystic fibrosis patients with normal to mildly impaired lung function by impairing the formation of sticky mucus, according to research published online Dec. 17 in the American Journal of Respiratory and Critical Care Medicine.
Report Addresses Vaccination Disparities in Older Adults
THURSDAY, Dec. 16 (HealthDay News) -- Older African-Americans and Hispanics are much less likely than older whites to get vaccinated against influenza and pneumonia, according to a report by the American Lung Association, "Missed Opportunities: Influenza and Pneumonia Vaccination in Older Adults."
HEPA Cleaners May Benefit Children With Asthma
THURSDAY, Dec. 16 (HealthDay News) -- High-efficiency, particle-arresting (HEPA) air cleaners may be useful as part of a larger strategy to reduce asthma morbidity in children exposed to secondhand tobacco smoke, according to research published online Dec. 13 in Pediatrics.
Mechanical Ventilation Tied to Greater Disability in Elderly
THURSDAY, Dec. 16 (HealthDay News) -- Elderly patients whose hospitalization includes a bout of mechanical ventilation (MV) may be more likely than hospitalized peers who do not experience MV to suffer long-term disabilities after leaving the hospital, according to research published online Nov. 5 in the American Journal of Respiratory and Critical Care Medicine.
Benzonatate Tied to Adverse Events in Young Children
WEDNESDAY, Dec. 15 (HealthDay News) -- The U.S. Food and Drug Administration has notified health care professionals and consumers that ingestion of the cough suppressant benzonatate (Tessalon) in children younger than 10 years of age may result in serious adverse events or death.
Protective Strategy Raises Number of Harvested Lungs
TUESDAY, Dec. 14 (HealthDay News) -- Use of a more protective ventilator strategy may increase the number of eligible and harvested lungs from potential organ donors with brain death, according to research published in the Dec. 15 issue of the Journal of the American Medical Association.
Electronic Nicotine Delivery Systems' Safety Questioned
TUESDAY, Dec. 14 (HealthDay News) -- Electronic cigarettes, known as electronic nicotine delivery systems (ENDS), are poorly designed and labeled, leading to safety concerns which might merit removal from the market, according to research published online Dec. 7 in Tobacco Control.
Smoking Laws Linked to Fewer Asthma Symptoms in Youths
MONDAY, Dec. 13 (HealthDay News) -- Smoke-free laws may reduce asthma symptoms in youths, and children in homes in which no one smokes indoors may have higher cotinine levels if they live in apartments compared to detached houses, according to research published online Dec. 13 in Pediatrics.
Death Rate in U.S. Down, but So Is Life Expectancy, Slightly
THURSDAY, Dec. 9 (HealthDay News) -- Life expectancy has declined slightly in the United States, stroke is no longer the third leading cause of death, and heart disease and cancer still account for nearly half of U.S. deaths; these and other statistics can be found in a new report from the U.S. Centers for Disease Control and Prevention, entitled "Deaths: Preliminary Data for 2008."
Brief, Slight Exposure to Smoke Can Still Cause Damage
THURSDAY, Dec. 9 (HealthDay News) -- Even very brief exposure to tobacco smoke may cause immediate damage that can have serious long-term consequences, according to a recently released Surgeon General's report, "How Tobacco Smoke Causes Disease: The Biology and Behavioral Basis for Smoking-Attributable Disease."
As Children Age, Smoking by Adults in Home More Likely
WEDNESDAY, Dec. 8 (HealthDay News) -- As children age, their family members are more likely to smoke inside the home, and older children are more likely to have recurrent ear infections if someone smokes inside the home, according to a study published online Dec. 8 in the Journal of Adolescent Health.
Regular Family Meetings Not Linked to Shorter ICU Stays
WEDNESDAY, Dec. 8 (HealthDay News) -- In long-stay intensive care unit (ICU) patients, regular discussions between family members and staff aren't associated with a shorter length of stay, according to research published in the December issue of Chest.
Radiographic Emphysema Not Predictive of Lung Cancer
TUESDAY, Dec. 7 (HealthDay News) -- Airflow obstruction in people at high risk of lung cancer appears to be a risk factor for the disease, a finding that falls in line with previous research, though there is not a clear relationship between quantitative radiographic evidence of emphysema and lung cancer, according to a study published in the December issue of Chest.
Asthma May Hamper Young Students' Reading Ability
TUESDAY, Dec. 7 (HealthDay News) -- Children who enter school with asthma may be more likely to have low reading achievement after 12 months, according to research published in the December issue of Chest.
Burnout Driving Away Many Emergency Physicians
THURSDAY, Dec. 2 (HealthDay News) -- Conflicts between work and family and poor on-the-job teamwork contribute to burnout and drive many physicians, particularly emergency physicians, to want to leave their profession, according to a study published online Dec. 1 in the Emergency Medicine Journal.
Bloodstream Infections Tied to Excess Mortality in ICU
WEDNESDAY, Dec. 1 (HealthDay News) -- Health-care-associated bloodstream infections and pneumonia appear to be strongly associated with increased mortality among patients admitted to intensive care units (ICUs), according to a study published online Dec. 1 in The Lancet Infectious Diseases.
Sleeping Problems Associated With Metabolic Syndrome
WEDNESDAY, Dec. 1 (HealthDay News) -- People who have trouble sleeping, particularly those with loud snoring, may be at increased risk for developing metabolic syndrome, according to research published in the Dec. 1 issue of SLEEP.