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Category: Rheumatology | Monthly Briefing

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December 2010 Briefing - Rheumatology

Last Updated: January 03, 2011.

 

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Here are what the editors at HealthDay consider to be the most important developments in Rheumatology for December 2010. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Hydroxychloroquine May Be Best in Certain Patients

THURSDAY, Dec. 30 (HealthDay News) -- Hydroxychloroquine (HCQ) initiation is associated with a significant reduction in glycosylated hemoglobin (HbA1c) levels, as compared with methotrexate (MTX) initiation, in patients suffering from both diabetes and rheumatic disease, according to a report published in the December issue of Arthritis & Rheumatism.

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Elevated IgA-RF, Pyridinoline Linked to Joint Erosion

THURSDAY, Dec. 30 (HealthDay News) -- Patients with early arthritis who have high levels of both IgA rheumatoid factor (IgA-RF) and pyridinoline are much more likely to develop one or more erosions within two years, according to a study published in the December issue of Arthritis Care & Research.

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Quadriceps Weakness Not Linked to OA in ACL Patients

WEDNESDAY, Dec. 29 (HealthDay News) -- There is no association between quadriceps muscle weakness after anterior cruciate ligament (ACL) reconstruction and subsequent knee osteoarthritis (OA), according to a report published in the December issue of Arthritis Care & Research.

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Pre-Radiographic OA May Affect Half of Knee Pain Sufferers

WEDNESDAY, Dec. 29 (HealthDay News) -- Nearly half of knee pain sufferers have evidence of pre-radiographic osteoarthritis (pre-ROA), with 38 percent having evidence of ROA, according to a report published in the December issue of Arthritis Care & Research.

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Fertility in Rheumatic Disease Patients Needs Priority

TUESDAY, Dec. 28 (HealthDay News) -- Reduced fertility is not uncommon in both male and female patients being treated for rheumatic diseases; therefore, family planning should be discussed with all patients requiring therapy with drugs that may impair fertility, according to a review published in the December issue of Arthritis Care & Research.

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Metabolic Syndrome Increases Risk of Hyperuricemia

FRIDAY, Dec. 24 (HealthDay News) -- Patients with metabolic syndrome (MetS) who have hyperuricemia are at increased risk of myocardial infarction (MI) and sudden cardiac death, according to a report published in the Dec. 15 issue of The American Journal of Cardiology.

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Researchers Assess State of Investigational Rheumatology

THURSDAY, Dec. 23 (HealthDay News) -- More funding for clinical research and a wider range of rheumatologists from underrepresented groups may be needed to narrow the gaps embedded in investigational rheumatology, according to a report published in the December issue of Arthritis & Rheumatism.

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Arthritis Risk Alleles Validated Across Ethnicities

WEDNESDAY, Dec. 22 (HealthDay News) -- The majority of validated risk alleles for patients with rheumatoid arthritis (RA) of European ancestry show similar odds ratios (ORs) in African-American patients with the condition, according to a report in the December issue of Arthritis & Rheumatism.

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Drinking Tied to Inflammatory Markers in Preclinical RA

MONDAY, Dec. 20 (HealthDay News) -- Daily alcohol intake shows a U-shaped association with interleukin-6 (IL-6) levels and an inverse relationship with soluble tumor necrosis factor receptor II (sTNFRII) levels, both biomarkers of inflammation, before onset of rheumatoid arthritis (RA) symptoms, according to research published in the December issue of Arthritis & Rheumatism.

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Smoking Blamed for One-Third of Severe RA Cases

MONDAY, Dec. 20 (HealthDay News) -- Smoking is a preventable risk factor for rheumatoid arthritis, with risk dependent on the amount of smoking and genetic predisposition, according to a study published online Dec. 13 in Annals of the Rheumatic Diseases.

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Rheumatoid Arthritis Linked to Early Myocardial Infarction Risk

TUESDAY, Dec. 14 (HealthDay News) -- Following a diagnosis of rheumatoid arthritis (RA), individuals may face a rapidly increasing risk of myocardial infarction (MI), according to research published in the December issue of the Journal of Internal Medicine.

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Calif. Health Plan Registries Track Orthopedic Outcomes

FRIDAY, Dec. 10 (HealthDay News) -- Registries maintained by a large California health plan for knee and hip replacement and knee ligament reconstruction surgery could provide models for currently-lacking national registries for these major orthopedic surgeries, according to an article published in a supplement to the Dec. 1 issue of the Journal of Bone & Joint Surgery.

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Etanercept Improves Growth in Children With JIA

THURSDAY, Dec. 2 (HealthDay News) -- Etanercept alone or in combination with methotrexate (MTX) may mitigate the potentially permanent growth retardation associated with juvenile idiopathic arthritis (JIA), according to research published in the November issue of Arthritis & Rheumatism.

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Burnout Driving Away Many Emergency Physicians

THURSDAY, Dec. 2 (HealthDay News) -- Conflicts between work and family and poor on-the-job teamwork contribute to burnout and drive many physicians, particularly emergency physicians, to want to leave their profession, according to a study published online Dec. 1 in the Emergency Medicine Journal.

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Early Rheumatoid Arthritis Evaluation Improves Outcomes

WEDNESDAY, Dec. 1 (HealthDay News) -- Delayed assessment of rheumatoid arthritis (RA) patients appears to be associated with more joint destruction and a lower probability of a disease-modifying antirheumatic drug (DMARD)-free remission, but there is still a delay to assessment of at least 12 weeks in more than two-thirds of patients, according to a study published in the December issue of Arthritis & Rheumatism.

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