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Category: Pediatrics | Monthly Briefing

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February 2011 Briefing - Pediatrics

Last Updated: March 01, 2011.

 

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Here are what the editors at HealthDay consider to be the most important developments in Pediatrics for February 2011. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Cigarette Smoking Associated With Congenital Heart Defects

MONDAY, Feb. 28 (HealthDay News) -- Women who smoke cigarettes during the first trimester of pregnancy may increase their offspring's risk for congenital heart defects (CHDs), according to research published online Feb. 28 in Pediatrics.

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Guidance Given for Antipyretic Use in Febrile Children

MONDAY, Feb. 28 (HealthDay News) -- Antipyretics should be used judiciously when treating children with fever, and the goal should be the child's comfort rather than normal temperature, according to a clinical report published online Feb. 28 in Pediatrics.

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Less Cerebral Oxygenation Seen in Prone-Sleeping Infants

MONDAY, Feb. 28 (HealthDay News) -- Infants experience decreased cerebral oxygenation while sleeping on their stomachs, which may give insight into the increased risk of sudden infant death syndrome associated with prone sleeping, according to research published online Feb. 28 in Pediatrics.

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Adequate Breast-Feeding Tied to Less Childhood Adiposity

MONDAY, Feb. 28 (HealthDay News) -- Adequate breast-feeding of a baby exposed to diabetes in utero may protect against childhood adiposity, according to a study published in the March issue of Diabetes Care.

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Intensive Diabetes Treatment May Slow Atherosclerosis

THURSDAY, Feb. 24 (HealthDay News) -- Intensive treatment of type 1 diabetes slows the progression of atherosclerosis during a 12-year period after therapy, according to a study published in the February issue of Diabetes.

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Eating Breakfast Tied to Lower BMI in Postpartum Teens

THURSDAY, Feb. 24 (HealthDay News) -- Postpartum teens who eat breakfast on most days consume fewer calories from snacks and sweetened drinks, and have a lower body mass index (BMI) than those who tend to skip breakfast, according to a study published in the January issue of the Journal of the American Dietetic Association.

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Early Appendectomy Favored in Youths

THURSDAY, Feb. 24 (HealthDay News) -- Children with perforated appendicitis who undergo an appendectomy within 24 hours of hospital admission spend significantly less time away from normal activities and experience fewer adverse events compared to those who undergo removal six to eight weeks after diagnosis, according to a study published online Feb. 21 in the Archives of Surgery.

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Later Onset of Childhood Type 1 Diabetes Revealed

THURSDAY, Feb. 24 (HealthDay News) -- The trend toward the earlier onset of childhood type 1 diabetes (T1D) is undergoing a statistically significant reversal in Sweden, according to a study published in the February issue of Diabetes.

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Family Mealtime Interaction Affects Children's Health

THURSDAY, Feb. 24 (HealthDay News) -- The health of children with persistent asthma is linked to the quality of social interaction with their families during mealtime, according to a study published in the January/February issue of Child Development.

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Microbial Exposure May Protect Against Asthma

WEDNESDAY, Feb. 23 (HealthDay News) -- There appears to be an inverse relationship between asthma and exposure to a wide variety of microbes, according to comparative analyses of children who grow up on farms and those who do not; the results have been published in the Feb. 24 issue of the New England Journal of Medicine.

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Distinctions Found Between Types of Hemoglobin H Disease

WEDNESDAY, Feb. 23 (HealthDay News) -- Patients with hemoglobin H disease caused by hemoglobin H Constant Spring (HCS) appear to be at much higher risk for poor outcomes than those whose disease is caused by deletion of three out of four α-globin genes (HbH), according to research published in the Feb. 24 issue of the New England Journal of Medicine.

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Brain Waves Used to Identify Autism Disorders in Infants

WEDNESDAY, Feb. 23 (HealthDay News) -- A new noninvasive test, using the standard electroencephalogram (EEG) to compute modified multiscale entropy (mMSE), may be a useful predictor of an infant's risk for autism, according to a study published online Feb. 22 in BMC Medicine.

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Ultrasound Detects Silent Enthesitis in Arthritis

WEDNESDAY, Feb. 23 (HealthDay News) -- Ultrasonography with power Doppler (US-PD) may detect clinically silent enthesitis in patients with juvenile idiopathic arthritis (JIA) and other enthesitis-related arthritis, according to research published online Feb. 10 in Arthritis Care & Research.

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Type 1 Diabetes Tied to Shorter Breast-Feeding Duration

WEDNESDAY, Feb. 23 (HealthDay News) -- Although mothers with type 1 diabetes are less likely to partially or exclusively breast-feed at two months, diabetes is not an independent risk factor for the initiation and maintenance of breast-feeding, according to a study published in the February issue of Diabetes Care.

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FDA Issues Label Changes for Antipsychotic Drug Class

TUESDAY, Feb. 22 (HealthDay News) -- The U.S. Food and Drug Administration has notified health care providers that the Pregnancy section of drug labels for the entire class of antipsychotic drugs has been updated. The new drug labels include additional and consistent information regarding the potential risk for abnormal muscle movements (extrapyramidal signs [EPS]) and withdrawal symptoms among newborns whose mothers received the drugs in the third trimester of pregnancy.

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Children With Hepatitis C May Benefit From Ribavirin

TUESDAY, Feb. 15 (HealthDay News) -- The combination of pegylated interferon (PEG) plus ribavirin is better than PEG plus placebo for treating children infected with hepatitis C virus (HCV), according to a study published in the February issue of Gastroenterology.

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Bone-Anchored Hearing Aid Beneficial for Children

TUESDAY, Feb. 22 (HealthDay News) -- Bone-anchored hearing aid (BAHA) fitting can be beneficial for children with bilateral or unilateral conductive hearing loss, according to a study published in the February issue of the Archives of Otolaryngology -- Head & Neck Surgery.

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Multiple Concussions in Youth Tied to Various Issues

MONDAY, Feb. 21 (HealthDay News) -- High school athletes with a history of multiple concussions appear to have more cognitive, physical, and sleep problems, according to a study published online Jan. 6 in Neurosurgery.

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Many Young Drinkers Get Drinks From Home

MONDAY, Feb. 21 (HealthDay News) -- About 709,000 adolescents aged 12 to 14 in the United States report drinking in the last month, and a substantial number of them get their alcohol from family or at home, according to new research released by the Substance Abuse and Mental Health Services Administration (SAMHSA).

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Nonsuicidal Self-Injury Videos Accessible on YouTube

MONDAY, Feb. 21 (HealthDay News) -- The majority of nonsuicidal self-injury (NSSI) videos on YouTube are accessible to the general public and are positively rated and frequently viewed, according to a study published online Feb. 21 in Pediatrics.

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Immunosuppressants Benefit Children With Liver Failure

MONDAY, Feb. 21 (HealthDay News) -- Most children with autoimmune hepatitis (AIH) who have liver failure respond well to immunosuppression therapy and can delay or avoid liver transplants, according to a study published in the February issue of Clinical Gastroenterology and Hepatology.

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Long Maternal Working Hours Linked to Children's BMI

MONDAY, Feb. 21 (HealthDay News) -- An increase in the total time that a mother is employed is associated with an increase in her child's body mass index (BMI), according to a study published in the January/February issue of Child Development.

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Teen Drinking May Lead to Adult Alcohol Dependence

MONDAY, Feb. 21 (HealthDay News) -- Evidence suggests that higher alcohol consumption in late adolescence continues into adulthood and is associated with alcohol-related problems such as dependence, according to a literature review published online Feb. 8 in PLoS Medicine.

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Considerable Lack of Test Result Follow-Up in Hospitals

MONDAY, Feb. 21 (HealthDay News) -- Failure to follow up on test results is a considerable problem, which can negatively impact patient health, according to a review published in the February issue of BMJ Quality & Safety.

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Low Pay for New Female Doctors Tied to Gender, Not Job

MONDAY, Feb. 21 (HealthDay News) -- In 2008, male physicians who were newly trained in New York State made an average of $16,819 more than newly trained female physicians, compared to a $3,600 difference in 1999, according to a study published in the February issue of Health Affairs.

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Pediatric Kingella Kingae Cases Require Vigilance

FRIDAY, Feb. 18 (HealthDay News) -- Despite the subtle clinical presentation of Kingella kingae (K. kingae) infection, it is increasingly becoming recognized as a common cause of pediatric diseases, highlighting the importance of a high index of suspicion, according to a review published online Feb. 14 in Pediatrics.

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Exercise Improves Executive Function in Children

FRIDAY, Feb. 18 (HealthDay News) -- Exercise is associated with improved executive function and mathematical achievement in children, according to a study published in the January issue of Health Psychology.

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Analysis of Routine Tonsillectomy Questioned

FRIDAY, Feb. 18 (HealthDay News) -- Due to the low prevalence of unsuspected pathology on gross pathologic evaluation of specimens from routine pediatric tonsillectomy, histologic evaluation may not be cost-effective, according to a study published online Jan. 31 in Otolaryngology -- Head and Neck Surgery.

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CDC: U.S. Influenza Activity Rates Up Since Mid-December

THURSDAY, Feb. 17 (HealthDay News) -- Influenza activity rates began increasing in mid-December 2010, and influenza-related hospitalizations have been highest among very young children and the elderly, according to a report in the Feb. 18 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Number of Pediatric Injuries Involving Cribs Fairly High

THURSDAY, Feb. 17 (HealthDay News) -- For every 10,000 children younger than 2 years in the United States, there are slightly more than 12 injuries related to cribs, playpens, and bassinets that result in an emergency department visit each year, according to research published online Feb. 17 in Pediatrics.

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Earlier Puberty Tied to Greater Bone Mass

THURSDAY, Feb. 17 (HealthDay News) -- Bone mass and bone density in healthy adolescent males and females are inversely related to the age at which puberty starts, according to research published in the January issue of The Journal of Pediatrics.

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Bevacizumab Monotherapy Effective for Infant Retinopathy

WEDNESDAY, Feb. 16 (HealthDay News) -- Bevacizumab, a vascular endothelial growth factor inhibitor, appears to be more beneficial for zone I stage 3+ retinopathy of prematurity than laser treatment, though more research is needed to determine the therapy's safety, according to research published in the Feb. 17 issue of the New England Journal of Medicine.

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New U.S. Report on the Nation's Health 2010 Released

WEDNESDAY, Feb. 16 (HealthDay News) -- The U.S. Centers for Disease Control and Prevention's National Center for Health Statistics' 34th annual report, presenting the latest information on health status and determinants, utilization of health care, health care resources, expenditures, and a special feature on death and dying, was published Feb. 16.

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Zinc May Reduce Duration and Severity of Common Cold

WEDNESDAY, Feb. 16 (HealthDay News) -- Zinc taken within 24 hours of common cold symptoms reduces symptom duration and severity; and preventive zinc therapy in children reduces cold incidence, missing school, and antibiotic prescriptions, according to a review published online Feb. 16 in the Cochrane Database of Systematic Reviews.

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Child Outpatient Pneumonia Rates Unaffected by Vaccine

WEDNESDAY, Feb. 16 (HealthDay News) -- Despite introduction of the heptavalent pneumococcal conjugate vaccine in 2000, incidence rates of community-acquired pneumonia (CAP) did not change between 1997 and 2004, according to a study published online Feb. 14 in Pediatrics.

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Hospital Readmissions Higher for Blacks Than for Whites

TUESDAY, Feb. 15 (HealthDay News) -- Blacks tend to have a higher level of hospital readmissions than whites, and, in children, a small percentage of patients with recurrent admissions make up a fairly large proportion of overall admissions, according to two articles published in the Feb. 16 issue of the Journal of the American Medical Association.

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Most Recalled Medical Devices Given Lenient Approval

TUESDAY, Feb. 15 (HealthDay News) -- The majority of medical devices recalled from 2005 to 2009 for risk of serious health hazard or death were approved by the less strict 510(k) process intended for devices considered low or moderate risk, according to a study published online Feb. 14 in the Archives of Internal Medicine.

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Developmental Delays More Likely in Late Preterm Infants

TUESDAY, Feb. 15 (HealthDay News) -- Late preterm infants are more likely than term infants to have mental or physical developmental delays and poorer neurodevelopmental outcomes, according to research published online Feb. 14 in Pediatrics.

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Abnormal Hand Control May Indicate ADHD Severity

TUESDAY, Feb. 15 (HealthDay News) -- Hand movement control measurements can be used in determining the severity of attention-deficit/hyperactivity disorder (ADHD) in children, according to two studies published in the Feb. 15 issue of Neurology.

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Corticosteroid Effective Asthma Rescue Addition

TUESDAY, Feb. 15 (HealthDay News) -- Inhaled corticosteroids as rescue medication with albuterol may be a useful step-down strategy for children with well-controlled, mild asthma as it is more effective at reducing exacerbations than is use of rescue albuterol alone in this population, according to a study published online Feb. 15 in The Lancet.

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Increase Seen in Pediatric Running Injuries

MONDAY, Feb. 14 (HealthDay News) -- A growing number of children are injuring themselves while running, suggesting a need for scientific, evidence-based research to create guidelines that will help reduce pediatric running-related injuries, according to a study in the February issue of Clinical Pediatrics.

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High Energy Drink Consumption by Teens Worrisome

MONDAY, Feb. 14 (HealthDay News) -- Energy drinks have no therapeutic benefit and contain ingredients which are not well studied and are not regulated, according to a review published online Feb. 14 in Pediatrics.

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Teens Prefer Pedicle Screw Result Over Hybrid Construct

MONDAY, Feb. 14 (HealthDay News) -- Adolescent patients undergoing surgery for scoliosis report improved postoperative appearance when all pedicle screws are used versus less costly hybrid constructs, according to a study published in the Feb. 1 issue of Spine.

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Joint Effusions Signal Possible Lyme Arthritis

MONDAY, Feb. 14 (HealthDay News) -- Children with joint effusions in a Lyme-endemic area of the Northeastern United States may have Lyme arthritis, especially if there is knee involvement, according to a study published in the Feb. 2 issue of The Journal of Bone & Joint Surgery.

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X-Rays in Utero, Early Infancy Could Raise Cancer Risk

FRIDAY, Feb. 11 (HealthDay News) -- In utero and early infancy exposure to diagnostic X-rays may increase the risk for childhood cancers, according to research published online Feb. 10 in BMJ.

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Children in Kinship Care May Fare Better Behaviorally

FRIDAY, Feb. 11 (HealthDay News) -- Children placed in kinship homes tend to fare better behaviorally and socially than children placed in foster care, though they may be at greater risk for pregnancy and substance use in adolescence, and their caregivers receive fewer support services, according to research published in the February issue of the Archives of Pediatrics & Adolescent Medicine.

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Childhood Obesity Tied to Screen Time, School Lunches

FRIDAY, Feb. 11 (HealthDay News) -- Watching television, playing computer games, and eating school lunches are all independently associated with childhood obesity; whereas, exercise has a preventive effect, according to a study published in the December issue of the American Heart Journal.

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Enteric Sickness in Schools Often Has Foodborne Source

FRIDAY, Feb. 11 (HealthDay News) -- Outbreaks of gastrointestinal illnesses among students frequently stem from a foodborne source and are mostly bacterial in nature; hand washing is often recommended to prevent outbreaks, according to a study published in the December issue of the Journal of School Health.

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Indoor Coal Use May Slow Children's Growth

FRIDAY, Feb. 11 (HealthDay News) -- Exposure to household, coal-derived pollution may stunt the growth of children whose families rely on coal for heating, according to research published online Feb. 7 in the Archives of Pediatrics & Adolescent Medicine.

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Paternal Cancer Offspring Risk Major Birth Anomalies

THURSDAY, Feb. 10 (HealthDay News) -- Children of male cancer survivors are slightly more likely to have major congenital birth abnormalities than those born to fathers without a history of cancer, regardless of whether they were conceived naturally or using assisted reproductive technologies (ARTs), according to research published online Feb. 8 in the Journal of the National Cancer Institute.

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Post-High School Adults With Autism Use Fewer Services

THURSDAY, Feb. 10 (HealthDay News) -- A large percentage of young adults with an autism spectrum disorder (ASD) do not use services after leaving high school; service rates vary according to race and socio-economic status, according to a study published in the February issue of the Archives of Pediatrics & Adolescent Medicine.

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Piperonyl Butoxide Tied to Mental Development Delay

THURSDAY, Feb. 10 (HealthDay News) -- Prenatal exposure to piperonyl butoxide may delay mental development at 36 months of age, according to research published online Feb. 7 in Pediatrics.

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Public Sector Plays Big Role in Drug Research

WEDNESDAY, Feb. 9 (HealthDay News) -- Public-sector research institutions (PSRIs) appear to play a bigger role in drug discovery than was previously thought, contributing to the discovery of about 10 to 20 percent of drugs approved for new drug applications since 1990, according to research published in the Feb. 10 issue of the New England Journal of Medicine.

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Prenatal Myelomeningocele Surgery Improves Outcomes

WEDNESDAY, Feb. 9 (HealthDay News) -- Prenatal surgery for myelomeningocele decreases the need for shunting and improves motor outcomes at 30 months, though it is linked to an increased risk of preterm delivery and uterine dehiscence at delivery, according to a study published online Feb. 9 in the New England Journal of Medicine.

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Obese Children Have Sustained Benefit From Intervention

WEDNESDAY, Feb. 9 (HealthDay News) -- Obese children with ethnically diverse backgrounds benefit from an intensive lifestyle program, and these benefits can be sustained 12 months after completion of the program, according to a study published online Feb. 7 in Pediatrics.

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Errors in Hospital Analgesia Prescriptions Nearly 3 in 1,000

WEDNESDAY, Feb. 9 (HealthDay News) -- Analgesic drug errors in hospitals occur at a rate of almost three per 1,000 prescriptions, and more than twice that among pediatric patients, according to a study published in the January issue of the Journal of Pain.

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Earlier Onset of Psychosis Linked to Cannabis Use

WEDNESDAY, Feb. 9 (HealthDay News) -- Cannabis use is related to the earlier onset of psychotic symptoms among users of the drug compared to nonusers, according to a review published online Feb. 7 in the Archives of General Psychiatry.

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Diet May Affect Development of Intelligence in Childhood

WEDNESDAY, Feb. 9 (HealthDay News) -- The type of diet a child consumes may have an impact on their IQ, according to research published online Feb. 7 in the Journal of Epidemiology and Community Health.

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Preterm Birth Linked to Impaired Memory

WEDNESDAY, Feb. 9 (HealthDay News) -- Adolescents who were born preterm have an increased risk of impaired executive function and memory, according to a study published online Feb. 7 in Pediatrics.

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Antenatal HIV Exposure Tied to Lower Infant Antibodies

TUESDAY, Feb. 8 (HealthDay News) -- Infants exposed to HIV in the womb, but not infected at birth, have lower infant-specific antibody responses against some diseases, compared to infants not exposed to HIV, according to a study published in the Feb. 9 issue of the Journal of the American Medical Association.

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Faster Preemie Weight Gain Tied to Better Lung Function

TUESDAY, Feb. 8 (HealthDay News) -- Longitudinal measures of pulmonary function in infants and young children with bronchopulmonary dysplasia show significant airflow obstruction and restriction, which persists with time; however, infants with above-average weight gain show greater lung growth, according to a study published online Nov. 17 in Pediatric Pulmonology.

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ADHD Often Linked to Other Mental Health Disorders

TUESDAY, Feb. 8 (HealthDay News) -- Children with attention deficit/hyperactivity disorder (ADHD) are more likely to have other mental health or neurodevelopmental conditions, and their social and educational functions worsen with more comorbidities, according to a study published online Feb. 7 in Pediatrics.

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Early Introduction of Solid Food Tied to Obesity

MONDAY, Feb. 7 (HealthDay News) -- Introducing solid food to formula-fed infants who are under 4 months, or to infants weaned before the age of 4 months, is associated with an increased likelihood of obesity at the age of 3 years, according to a study published online Feb. 7 in Pediatrics.

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Drug Approved to Help Prevent Preterm Birth

FRIDAY, Feb. 4 (HealthDay News) -- Makena (hydroxyprogesterone caproate) has been approved by the U.S. Food and Drug Administration to help prevent birth before 37 weeks of pregnancy in women who have had at least one prior early delivery.

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Restricted Diet Can Identify Food-Induced ADHD

FRIDAY, Feb. 4 (HealthDay News) -- Dietary restriction may be a useful tool in the treatment of attention-deficit hyperactivity disorder (ADHD) in children, according to research published in the Feb. 5 issue of The Lancet.

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Strong Association Between Enterovirus and Diabetes Found

FRIDAY, Feb. 4 (HealthDay News) -- A review of molecular studies has found a strong association between enterovirus infection and the development of type 1 diabetes; the research has been published online Feb. 3 in BMJ.

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Single Dose of H1N1 Vaccine Highly Effective in Young

FRIDAY, Feb. 4 (HealthDay News) -- A single dose of H1N1 vaccine administered during the fall of 2009 in Canada appears to have been more than 90 percent effective in protecting recipients, particularly children and young adults, from the pandemic, according to research published online Feb. 3 in BMJ.

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Different Antiretroviral Drugs Found Effective in Children

THURSDAY, Feb. 3 (HealthDay News) -- Protease inhibitors (PIs) and non-nucleoside reverse transcriptase inhibitors (NNRTIs) appear to be equally effective as part of first-line treatment for HIV-infected children, and delaying the switch to second-line drugs has minimal impact on long-term viral load outcomes, according to a study published online Feb. 1 in The Lancet Infectious Diseases.

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Early Prophylaxis Effective for Children With Hemophilia

THURSDAY, Feb. 3 (HealthDay News) -- Prophylactic treatment of bleeding and arthropathy in children with hemophilia A is effective, particularly when initiated early in life, according to a study published online Jan. 21 in the Journal of Thrombosis and Haemostasis.

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Good Response to Omalizumab at 16 Weeks Is Predictive

THURSDAY, Feb. 3 (HealthDay News) -- For the majority of patients, response to omalizumab is an effective predictor of continuing persistent response to omalizumab, according to a study published online Jan. 21 in Allergy.

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Pediatric Stroke Survivors Have Lower Quality of Life

THURSDAY, Feb. 3 (HealthDay News) -- Health-related quality of life (HR-QoL) in terms of overall well-being of pediatric stroke survivors is lower compared with healthy controls, according to a study published online Jan. 24 in the Annals of Neurology.

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Givinostat a Promising Treatment for Juvenile Arthritis

THURSDAY, Feb. 3 (HealthDay News) -- Treatment of systemic onset juvenile idiopathic arthritis (SOJIA) with Givinostat, an orally active histone deacetylase inhibitor, for 12 weeks appears to be safe, well-tolerated, and effective, according to a study published online Jan. 18 in Arthritis & Rheumatism.

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H1N1 Vaccine Appears Safe

WEDNESDAY, Feb. 2 (HealthDay News) -- Adverse events associated with influenza A (H1N1) vaccine appear to be limited and relatively rare, and there is no evidence of an increased risk of Guillain-Barré syndrome associated with the virus, according to research published online Feb. 2 in the New England Journal of Medicine.

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Vaccine Prevents Human Papillomavirus in Males

WEDNESDAY, Feb. 2 (HealthDay News) -- Vaccination against human papillomavirus (HPV) appears effective in preventing HPV-6, 11, 16, and 18 as well as the development of external genital lesions in boys and men, according to research published in the Feb. 3 issue of the New England Journal of Medicine.

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CDC: U.S. Teenage Birth Rate Declines, Reaches Low

WEDNESDAY, Feb. 2 (HealthDay News) -- The U.S. teenage birth rate has resumed its decline, reaching a historic low in 2009, according to a report published in the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS) February Data Brief.

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Cause of Fever in Febrile Seizures Needs to Be Identified

WEDNESDAY, Feb. 2 (HealthDay News) -- Clinicians evaluating infants or young children following a simple febrile seizure should focus on identifying the cause of the fever, according to new guidelines published in the February issue of Pediatrics.

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Immunization Schedules for Children, Adolescents Updated

TUESDAY, Feb. 1 (HealthDay News) -- The American Academy of Pediatrics has released its 2011 recommended childhood and adolescent immunization schedules, which have been published in the February issue of Pediatrics.

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Tonsillectomy, Adenoidectomy Tied to Weight Gain

TUESDAY, Feb. 1 (HealthDay News) -- Normal and overweight children who undergo tonsillectomy or adenoidectomy gain a greater amount of weight than expected after the operation, according to a review published online Jan. 4 in Otolaryngology -- Head and Neck Surgery.

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Long-Term Sequelae Affect Childhood Meningitis Survivors

TUESDAY, Feb. 1 (HealthDay News) -- Survivors of childhood bacterial meningitis may have long-term academic and behavioral limitations, and other long-term sequelae, according to a review published in the January issue of The Pediatric Infectious Disease Journal.

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