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Category: Gynecology | Monthly Briefing

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April 2011 Briefing - OBGYN & Women’s Health

Last Updated: May 02, 2011.

 

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Here are what the editors at HealthDay consider to be the most important developments in OBGYN & Women's Health for April 2011. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Weight Linked to Post-Hysterectomy Complications

FRIDAY, April 29 (HealthDay News) -- Obesity is associated with increased risk of bleeding and infection after abdominal hysterectomy (AH), while having a body mass index (BMI) of less than 20 kg/m² is linked with bleeding and infection after both AH and laparoscopic hysterectomy (LH), according to a study published online April 5 in Human Reproduction.

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Children of Depressed Parents Experience More Stress

FRIDAY, April 29 (HealthDay News) -- Young children respond to stressful situations with higher levels of the stress hormone cortisol when their parents have a history of depression and exhibit negative behavior toward them, according to a study published online April 1 in Psychological Science.

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Fractures Seen in Older Levothyroxine Users

FRIDAY, April 29 (HealthDay News) -- Older people who take levothyroxine may be at risk for fractures, particularly if their cumulative doses are medium or high, according to research published online April 28 in BMJ.

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Height and Obesity May Raise Venous Thromboembolism Risk

FRIDAY, April 29 (HealthDay News) -- Tall men may have an increased risk of venous thromboembolism (VTE); whereas tall stature and obesity are associated with an increased VTE risk in both men and women, according to a study published online April 28 in Arteriosclerosis, Thrombosis, and Vascular Biology.

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Increasing Cancer Burden Projected for Ethnic Minorities

THURSDAY, April 28 (HealthDay News) -- Consideration of genetic, ethnic, biologic, and sociological factors is necessary to appropriately diagnose and treat cancer in all U.S. subpopulations, according to the President's Cancer Panel 2009 to 2010 report published April 28.

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Strategy Found Effective for Women With Cervical Neoplasia

THURSDAY, April 28 (HealthDay News) -- Women with a history of high-grade cervical intraepithelial neoplasia (CIN grade 2 or 3) who have had three consecutive negative cytological smears are at a similar five-year risk of developing cervical cancer or recurrent disease as women in the general population, according to a study published online April 28 in The Lancet Oncology.

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Tanezumab Relieves Interstitial Cystitis Pain

THURSDAY, April 28 (HealthDay News) -- A single dose of intravenous (IV) tanezumab may alleviate interstitial cystitis pain, according to a study published in the May issue of The Journal of Urology.

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Obesity in Pregnancy Linked to Fetal and Infant Death

THURSDAY, April 28 (HealthDay News) -- Early pregnancy obesity significantly increases the risk of fetal and infant death, independent of risks associated with congenital anomalies and maternal pre-gestational diabetes, according to a study published online April 5 in Human Reproduction.

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Serum Peptide Levels Linked to Subsequent Preterm Birth

WEDNESDAY, April 27 (HealthDay News) -- The proteomic profile of specific serum peptides can be used to identify women at risk for spontaneous preterm birth (SPTB), according to a study published online Nov. 12, 2010, in the American Journal of Obstetrics & Gynecology.

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Oophorectomy May Not Adversely Affect Health

WEDNESDAY, April 27 (HealthDay News) -- Elective bilateral salpingo-oophorectomy (BSO) with hysterectomy is associated with a lower risk of ovarian cancer than ovarian conservation and hysterectomy, and BSO does not appear to have adverse effects on cardiovascular health, hip fracture, cancer, or total mortality compared with ovarian conservation and hysterectomy, according to research published in the April 25 issue of the Archives of Internal Medicine.

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Health Behavior Interventions Increase Healthy Behaviors

TUESDAY, April 26 (HealthDay News) -- Interventions targeting multiple health-related behaviors are successful at increasing health-related behaviors in HIV-serodiscordant heterosexual African-American couples, according to a study published in the April 25 issue of the Archives of Internal Medicine.

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AAP: Chemical Management Policy Needs Revision

MONDAY, April 25 (HealthDay News) -- Stating that the Toxic Substances Control Act (TSCA) of 1976 has failed to protect children, pregnant women, and others from marketplace exposure to harmful chemicals, the American Academy of Pediatrics (AAP) recommends current U.S. chemical management policy be revised, according to a policy report published online April 25 in Pediatrics.

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Risk Taking Similar in Very Obese, Normal Weight Teens

MONDAY, April 25 (HealthDay News) -- High school students (HSS) with extreme obesity appear to engage in risky behaviors at a rate similar to that of their healthy weight peers, with higher rates of some high-risk behaviors, according to research published online April 25 in Pediatrics.

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Policy Statement Addresses Chaperones in Pediatric Exams

MONDAY, April 25 (HealthDay News) -- Patient comfort, privacy, and confidentiality are matters to consider when it comes to the presence of chaperones during physical examinations of pediatric patients, according to a policy statement published online April 25 in Pediatrics.

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Hypertension Drugs Tied to Risk of Cancer Recurrence

MONDAY, April 25 (HealthDay News) -- Angiotensin-converting enzyme inhibitors (ACEi) appear to be associated with an elevated risk of breast cancer recurrence in women, while beta blockers (BBs) seem to have a protective effect, according to a study published online April 11 in Breast Cancer Research and Treatment.

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Ectopic Pregnancy Rates Increased in Recent Period

FRIDAY, April 22 (HealthDay News) -- Ectopic pregnancy rates in the United States increased over a recent 15-year period, according to a population-based study published in the May issue of the American Journal of Preventive Medicine.

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Studies Add to Evidence on Clot Risk Tied to Contraceptives

FRIDAY, April 22 (HealthDay News) -- Oral contraceptives containing drospirenone appear to be associated with a higher risk of non-fatal venous thromboembolism than formulations containing levonorgestrel, according to two studies published online April 21 in BMJ.

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Silicone Breast Implants Yield Good Aesthetic Results

FRIDAY, April 22 (HealthDay News) -- Immediate implant-based breast reconstruction has low complication rates and provides good aesthetic results, according to a study published in the April issue of Plastic and Reconstructive Surgery.

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Diabetes Does Not Affect Sexual Dysfunction Prevalence

FRIDAY, April 22 (HealthDay News) -- Sexual dysfunction in women with type 1 diabetes may be predicted by depression symptoms, but the prevalence is similar to that in women without type 1 diabetes, according to a study published online April 7 in The Journal of Sexual Medicine.

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Pesticide Exposure Tied to Lower IQ in Children

THURSDAY, April 21 (HealthDay News) -- Pesticide exposure appears to be associated with poorer IQ scores in children and may impair cognitive development, according to three studies published online April 21 in Environmental Health Perspectives.

Abstract - Rauh
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Intravaginal Probiotic May Lower UTIs in Premenopausal Women

THURSDAY, April 21 (HealthDay News) -- Treatment with an intravaginal suppository probiotic may help prevent recurrent urinary tract infection (UTI) in premenopausal women, according to research published online April 14 in Clinical Infectious Diseases.

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Behavioral Interventions Succeed in Promoting Condom Use

THURSDAY, April 21 (HealthDay News) -- Behavioral interventions in young women to promote safer sexual behaviors to protect against transmission of sexually transmitted infections (STIs) may be effective, primarily at encouraging condom use, according to a review published in the Cochrane Database of Systematic Reviews.

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Calcium Supplements Modestly Increase Risk of Heart Attack

WEDNESDAY, April 20 (HealthDay News) -- Use of personal calcium supplements -- with or without vitamin D -- modestly increases the risk of cardiovascular events, especially myocardial infarction (MI), a finding obscured in the Women's Health Initiative Calcium/Vitamin D Supplementation Study (WHI CaD Study), according to an article published online April 19 in BMJ.

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Physical Activity Guidelines May Improve Survival

WEDNESDAY, April 20 (HealthDay News) -- Meeting the recommendations set out in the federal 2008 Physical Activity Guidelines for Americans is associated with reduced all-cause mortality in U.S. adults, according to a study published online April 5 in the American Journal of Preventive Medicine.

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Progesterone Gel Linked With Lower Rate of Preterm Birth

WEDNESDAY, April 20 (HealthDay News) -- Administration of vaginal progesterone gel in women with a sonographically short cervix in the second trimester is correlated with a significant reduction in the rate of preterm birth, according to a study published online April 6 in Ultrasound in Obstetrics & Gynecology.

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Triple-Class Viral Failure Low in HIV-Infected Children

WEDNESDAY, April 20 (HealthDay News) -- The rate of triple-class virological failure to three or more antiretroviral therapy (ART) drugs in children infected perinatally with HIV is low, but higher than the rate in adults, according to a study published online April 20 in The Lancet.

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Maternal Obesity Linked to Neurodevelopmental Disorders

MONDAY, April 18 (HealthDay News) -- Maternal obesity and overweight may be linked to neurodevelopmental problems in offspring in childhood, adolescence, or adulthood, according to a review published online March 17 in Obesity Reviews.

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Post-Cancer Fatigue Linked to Autonomic Nervous System

MONDAY, April 18 (HealthDay News) -- The long-term fatigue that affects breast cancer survivors may be caused by higher sympathetic and lower parasympathetic activity, according to a study published online March 9 in Psychoneuroendocrinology.

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Insulin Resistance Linked to Increased Preeclampsia Risk

MONDAY, April 18 (HealthDay News) -- Mid-trimester maternal insulin resistance is associated with subsequent preeclampsia, according to a study published in the April issue of the American Journal of Obstetrics & Gynecology.

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Single Embryo Transfer Lowers Neonatal Complications

THURSDAY, April 14 (HealthDay News) -- Complications ensuing from multiple gestations after artificial reproductive technology (ART) have increased significantly in the last 10 years and represent a burden on neonatal intensive care units (NICU), according to a study published online April 14 in The Journal of Pediatrics.

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Stillbirth in High-Income Nations Tied to Modifiable Risks

THURSDAY, April 14 (HealthDay News) -- Stillbirth rates in high-income countries may be influenced by modifiable risk factors, but more than 75 percent of stillbirths occur in low-income countries where the reduction in stillbirth rates is happening at a slower pace than that of mortality in children under the age of 5, according to two articles published online April 14 as part of a special series on stillbirths in The Lancet.

Abstract - Flenady
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Abstract - Cousens
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Breast Cancer Screening Guidelines Confuse Women

THURSDAY, April 14 (HealthDay News) -- The new recommendations on breast cancer screening released by the U.S. Preventive Services Task Force confuse women more than they help them understand when to get a mammogram, according to a study published online April 5 in the American Journal of Preventive Medicine.

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More Than Half of U.S. Adults Take Dietary Supplements

WEDNESDAY, April 13 (HealthDay News) -- Adult U.S. dietary supplement intake has increased since 1988-1994, according to a National Center for Health Statistics (NCHS) data brief published April 13 by the U.S. Centers for Disease Control and Prevention.

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Central Hair Loss Prevalent in African-American Women

WEDNESDAY, April 13 (HealthDay News) -- Central centrifugal cicatricial alopecia (CCCA) appears to be highly prevalent in African-American women, and may be associated with type 2 diabetes, bacterial scalp infections, and hairstyles associated with traction, according to research published in the April issue of the Archives of Dermatology.

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Vitamin D Levels May Reduce Risk of Macular Degeneration

WEDNESDAY, April 13 (HealthDay News) -- Serum 25-hydroxyvitamin D (25[OH]D) concentrations may be associated with a reduced likelihood of developing early age-related macular degeneration (AMD) in women younger than 75 years, according to a study published in the April issue of the Archives of Ophthalmology.

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Alternative HPV Dosing Schedules Effective in Girls

TUESDAY, April 12 (HealthDay News) -- Human papillomavirus (HPV) standard schedule vaccine or alternative dosing schedules (zero, three, and nine months and zero, six, and 12 months) are well tolerated with comparable immunogenicity in adolescent girls, according to a study published April 13 in an infectious disease and immunology themed issue of the Journal of the American Medical Association.

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Increased Genital Shedding in Symptomatic HSV-2 Patients

TUESDAY, April 12 (HealthDay News) -- Genital shedding of herpes simplex virus type 2 (HSV-2) is less frequent in individuals with asymptomatic infection who also have less frequent genital lesions, according to a study published April 13 in an infectious disease and immunology themed issue of the Journal of the American Medical Association.

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SLN Biopsy Predicts Lymph Node Status in Endometrial CA

TUESDAY, April 12 (HealthDay News) -- Sentinel lymph node (SLN) biopsy appears promising as a less invasive alternative to complete lymphadenectomy for diagnosing lymph node status in patients with early-stage endometrial cancer, according to research published online April 12 in The Lancet Oncology.

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Negative Health Behaviors Identified in Young Parents

MONDAY, April 11 (HealthDay News) -- Parents of young children have lower physical activity levels compared to young adults of the same age without children, and mothers have poorer dietary intake and higher body mass index (BMI) compared to women without children, according to a study published online April 11 in Pediatrics.

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Antenatal Paracetamol Use May Be Tied to Childhood Wheeze

MONDAY, April 11 (HealthDay News) -- Children whose mothers used paracetamol during their pregnancy may have a slightly increased risk of childhood wheeze, according to a meta-analysis published in the April issue of Clinical & Experimental Allergy.

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Intrauterine Pregnancy More Likely With Malpositioned IUDs

MONDAY, April 11 (HealthDay News) -- Incorrectly positioned intrauterine devices (IUDs) make intrauterine pregnancy (IUP) more likely, with more than half of IUDs identified during the first trimester of pregnancy malpositioned, according to a study published online Feb. 24 in the American Journal of Obstetrics & Gynecology.

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'Global Trigger Tool' Identifies 10 Times More Errors

THURSDAY, April 7 (HealthDay News) -- Use of the new Global Trigger Tool, developed by the Institute for Healthcare Improvement, detects at least 10 times more adverse events than other methods currently in use, according to a study published in the April issue of Health Affairs.

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Partner Violence Victims Not Identified in Emergency Room

THURSDAY, April 7 (HealthDay News) -- Although most victims of intimate partner violence (IPV) present to the emergency department (ED), they are not usually identified and may not receive interventions, according to a study published online March 15 in the Journal of General Internal Medicine.

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Longer Breast-Feeding Tied to More Protective Adipokines

THURSDAY, April 7 (HealthDay News) -- The duration of breast-feeding is associated with higher maternal ghrelin and pancreatic peptide YY (PYY) levels at three years postpartum, independent of other risk factors for metabolic disease, according to a study published in the April issue of Diabetes.

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Controlling Behavior Tied to Violence in Relationships

WEDNESDAY, April 6 (HealthDay News) -- Young women who are subject to controlling behaviors from a partner and suffering from physical and sexual relationship violence (RV) are more reticent about screening for RV, according to a study published in the April issue of the Archives of Pediatrics & Adolescent Medicine.

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Non-Communicable Diseases Present a Global Health Crisis

WEDNESDAY, April 6 (HealthDay News) -- The global burden of non-communicable diseases (NCDs) is increasing, and a global movement is needed to tackle them, according to a report published online April 6 in The Lancet.

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Alteration in Health Outcomes Post Estrogen Therapy

TUESDAY, April 5 (HealthDay News) -- Among postmenopausal women with prior hysterectomy, cessation of conjugated equine estrogen (CEE) therapy reduces the risk of stroke, and the risk of breast cancer remains reduced, according to a study to be published on April 6 in the Journal of the American Medical Association.

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CDC: U.S. Teen Birth Rates Down but Remain High

TUESDAY, April 5 (HealthDay News) -- Teen birth rates in the United States have declined over the last two decades, but they remain high, according a Vital Signs report in the April 5 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Optical Coherence Tomography Identifies Cervical Cancer

MONDAY, April 4 (HealthDay News) -- Optical coherence tomography (OCT), a new imaging technology that allows noninvasive cross-sectional imaging, has high sensitivity for diagnosing cervical cancer, but low specificity, according to a study published in the March issue of Lasers in Surgery and Medicine.

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More Screening Lowers False-Positive Mammography Rate

MONDAY, April 4 (HealthDay News) -- U.S. radiologists with higher annual screening volumes and focus have statistically significant lower false-positive rates and cancer detection rates during mammography, according to a study published in the April issue of Radiology.

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Breast Cancer Survival Factors for Underserved Identified

MONDAY, April 4 (HealthDay News) -- Advanced stages at presentation, and limited diagnostic and treatment capabilities, contribute to lower breast cancer survival in low-income and middle-income countries (LMC), according to the executive summary of the Breast Health Global Initiative Consensus 2010, published in the April issue of The Lancet Oncology.

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Total Hip Arthroplasty Treats Developmental Hip Dysplasia

FRIDAY, April 1 (HealthDay News) -- Cementless modular total hip arthroplasty together with subtrochanteric osteotomy appears to be a satisfactory treatment for patients with prior Crowe Group-IV dysplasia of the hip, according to research published in the March 16 issue of The Journal of Bone & Joint Surgery.

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Low Nutrients Tied to Anemia Risk in Postmenopausal Women

FRIDAY, April 1 (HealthDay News) -- Inadequate nutrient intake is associated with greater risk for anemia in postmenopausal women, according to a study published in the April issue of the Journal of the American Dietetic Association.

Abstract
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Editorial (subscription or payment may be required)

Cancer Rates, Cancer Mortality Rates Falling in U.S.

FRIDAY, April 1 (HealthDay News) -- Newly diagnosed cancer rates and cancer-related mortality rates in the United States are steadily declining, according to the "Annual Report to the Nation on the Status of Cancer," published online March 31 in the Journal of the National Cancer Institute.

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Autoimmune Diseases Number Two Cause of Chronic Illness

FRIDAY, April 1 (HealthDay News) -- Autoimmune diseases are the second leading cause of chronic illness in the United States and constitute a major direct and indirect economic burden to the U.S. health care system, according to a report released by the American Autoimmune Related Diseases Association (AARDA) on March 22 at a congressional briefing.

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MRI Found to Improve Breast Cancer Detection Rate

FRIDAY, April 1 (HealthDay News) -- Using a combination of magnetic resonance (MR) imaging and mammography increases sensitivity of cancer detection in women with a history of chest irradiation compared to using either modality on its own, according to a study published in the April issue of Radiology.

Abstract
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Lower Exercise Tolerance in Patients With Turner Syndrome

FRIDAY, April 1 (HealthDay News) -- Women with Turner syndrome (TS) have lower maximal aerobic capacity and lower exercise tolerance than controls, according to a study published in the April 1 issue of The American Journal of Cardiology.

Abstract
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