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Category: Pathology | Monthly Briefing

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June 2011 Briefing - Pathology

Last Updated: July 01, 2011.

 

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Here are what the editors at HealthDay consider to be the most important developments in Pathology for June 2011. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Low-Dose CT Screening Tied to Reduced Lung Cancer Mortality

THURSDAY, June 30 (HealthDay News) -- Screening with low-dose helical computed tomography (CT) may reduce mortality from lung cancer, according to a study published online June 29 in the New England Journal of Medicine.

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Fewer Complications With NAFLD Than Hepatitis C Virus

THURSDAY, June 30 (HealthDay News) -- Patients with nonalcoholic fatty liver disease (NAFLD) with advanced fibrosis or cirrhosis may have fewer liver-related complications and less hepatocellular cancer than patients with hepatitis C virus (HCV) infection, but may have similar overall mortality, according to a study published online June 17 in Hepatology.

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Uncertainty of Diagnosis Tied to Increased Patient Anxiety

THURSDAY, June 30 (HealthDay News) -- Women awaiting diagnostic breast biopsy or invasive treatment experience increased stress levels, but only those awaiting biopsy have increased anxiety, according to a study published in the July issue of Radiology.

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Somatic Mutations Common in Myelodysplastic Syndromes

THURSDAY, June 30 (HealthDay News) -- Somatic point mutations are frequently found in myelodysplastic syndromes, and may be correlated with specific clinical features, according to a study published in the June 30 issue of the New England Journal of Medicine.

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Mutations Affect Susceptibility to Fungal Infection

WEDNESDAY, June 29 (HealthDay News) -- In patients with autosomal dominant chronic mucocutaneous candidiasis (CMC), mutations in signal transducer and activator of transcription 1 (STAT1) may be associated with increased susceptibility to fungal infections, according to a study published online June 29 in the New England Journal of Medicine.

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Hemochromatosis Linked to Death From Yersinia Exposure

WEDNESDAY, June 29 (HealthDay News) -- Attenuated strains of virulent laboratory organisms like Yersinia pestis (Y. pestis) may pose a risk to researchers with undiagnosed hemochromatosis, according to a letter published in the June 30 issue of the New England Journal of Medicine.

Letter to the Editor

Ambulatory BP Monitoring Can Predict Renal, Cardiac Risk

TUESDAY, June 28 (HealthDay News) -- In patients with chronic kidney disease (CKD), ambulatory blood pressure (BP) monitoring, especially at night, may predict renal and cardiovascular risks better than office BP measurements, according to a study published in the June 27 issue of the Archives of Internal Medicine.

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Mammography Invites Linked to Fewer Breast Cancer Deaths

TUESDAY, June 28 (HealthDay News) -- Invitation to mammographic screening is correlated with a significant reduction in mortality from breast cancer in the long term, according to a study published online June 28 in Radiology.

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Moderate, Severe Diastolic Dysfunction Predicts Mortality

TUESDAY, June 28 (HealthDay News) -- For patients with normal systolic function, the presence of moderate or severe diastolic dysfunction (DD) may be an independent predictor of cardiovascular mortality and survival rate, according to a study published in the June 27 issue of the Archives of Internal Medicine.

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New Model Estimates Impact of Breast-Cancer Risk Factors

TUESDAY, June 28 (HealthDay News) -- A new breast cancer risk model predicts that changes in the modifiable risk factors in a woman's lifestyle may reduce the absolute risk of developing breast cancer, according to a study published online June 24 in the Journal of the National Cancer Institute.

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Vitamin D, Calcium Don't Reduce Nonmelanoma Skin Cancer

TUESDAY, June 28 (HealthDay News) -- Low-dose vitamin D and calcium supplementation do not reduce the overall incidence of nonmelanoma skin cancer (NMSC) in postmenopausal women, but may benefit women with a history of NMSC, according to a study published online June 27 in the Journal of Clinical Oncology.

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New Tool Validated for Vision-Related Quality of Life

TUESDAY, June 28 (HealthDay News) -- The Effects of Youngsters' Eyesight on Quality of Life (EYE-Q) instrument is a validated and reliable tool which may be useful for determining vision-related quality of life (VRQOL) in visually impaired children with juvenile idiopathic arthritis-associated uveitis (JIA-U), according to a study published online June 15 in Arthritis Care & Research.

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Normal CT Scan Tied to Favorable Head Trauma Result

MONDAY, June 27 (HealthDay News) -- Children with minor blunt head injury with normal initial computed tomography (CT) scan results and a Glasgow Coma Scale (GCS) score of 14 to 15 are very unlikely to need neurosurgical intervention, according to a study published online June 17 in the Annals of Emergency Medicine.

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Cocaine Use Linked to Ear and Trunk Retiform Purpura

MONDAY, June 27 (HealthDay News) -- Use of cocaine may be associated with clinical findings of ear purpura, retiform purpura of the trunk, and neutropenia, according to a study published online June 9 in the Journal of American Academy of Dermatology.

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Harmful Fungi Found to Reside in Dishwasher Seals

MONDAY, June 27 (HealthDay News) -- Dishwashers, with high temperatures, moisture, and alkaline pH values, provide a habitat for pathogenic fungi, according to a study published online May 7 in Fungal Biology.

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More Pediatricians Utilizing Formal Screening Tools

MONDAY, June 27 (HealthDay News) -- An increased use of developmental tools by pediatricians was observed between 2002 and 2009, according to a study published online June 27 in Pediatrics.

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Higher Prevalence of Autism Disorders Seen in IT Regions

MONDAY, June 27 (HealthDay News) -- Autism spectrum conditions (ASC) are more common in children residing in regions which are centers of information technology (IT), according to a study published online June 17 in the Journal of Autism and Developmental Disorders.

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Home Stress Adds to Child's Lung Damage by Air Pollutants

FRIDAY, June 24 (HealthDay News) - The presence of psychosocial stress at home is correlated with increased susceptibility to the effects of traffic-related air pollution (TRP) on lung function, according to a study published online June 23 in the American Journal of Respiratory and Critical Care Medicine.

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Liver Fibrosis Tied to Hep C-Related Vasculitis Prognosis

FRIDAY, June 24 (HealthDay News) -- In patients with hepatitis C virus (HCV)-related systemic vasculitis, severity of liver fibrosis and vasculitis at baseline are associated with disease prognosis, according to a study published in the June issue of Arthritis & Rheumatism.

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Long-Term Pollutant Exposure Tied to Uncontrolled Asthma

FRIDAY, June 24 (HealthDay News) - Long-term exposure to particulate matter smaller than 10 µm (PM10) and ozone (O3) is associated with uncontrolled asthma in adults, according to a study published online June 20 in the Journal of Epidemiology & Community Health.

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Cardiac Magnetic Resonance Approach Feasible for Infants

FRIDAY, June 24 (HealthDay News) -- Cardiac magnetic resonance (CMR) using a feed-and-swaddle approach does not require deep sedation or cardiac anesthesia, and can be used to evaluate aortic arch abnormalities in infants, according to a study published in the July 1 issue of The American Journal of Cardiology.

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Poor Bowel Preparation Tied to Missed Adenoma Diagnosis

FRIDAY, June 24 (HealthDay News) -- Patients who undergo colonoscopies with suboptimal preparation of the bowel may have missed adenoma diagnoses, which are detected at repeat colonoscopy, according to a study published in the June issue of Gastrointestinal Endoscopy.

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CDC: Expanded HIV Testing Initiative Effective

THURSDAY, June 23 (HealthDay News) -- Initiatives to expand HIV testing, including an opt-out HIV screening approach used among inmates during prison medical intake evaluation, appear to be effective in identifying new HIV cases, according to two reports in the June 24 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Combined Virulence Identified in E. coli O104:H4

THURSDAY, June 23 (HealthDay News) -- The high virulence of Escherichia coli (E. coli) O104:H4 may be due to the strain having combined virulence of Shiga-toxin-producing and enteroaggregative E. coli, and augmented adherence to intestinal cells, according to a study published online June 23 in The Lancet Infectious Diseases.

Abstract
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Editorial (subscription or payment may be required)

New Biomarker May Identify Early Alzheimer's Disease

THURSDAY, June 23 (HealthDay News) -- Soluble amyloid precursor proteinβ (sAPPβ) may be a useful biomarker for incipient Alzheimer's disease (AD), according to a study published online June 22 in Neurology.

Abstract
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Autism Tied to Disrupted Neural Synchronization

THURSDAY, June 23 (HealthDay News) -- Toddlers with autism display disrupted neural synchronization during sleep compared to language-delayed or typically developing children, according to a study published in the June 23 issue of Neuron.

Abstract
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Maternal Smoking May Lower Children's HDL Cholesterol

THURSDAY, June 23 (HealthDay News) -- Healthy 8-year-olds whose mothers smoked during pregnancy may have reduced levels of high-density lipoprotein (HDL) cholesterol, according to a study published online June 21 in the European Heart Journal.

Abstract
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New Drug Targets Found for Benign Prostatic Hyperplasia

THURSDAY, June 23 (HealthDay News) -- Novel drug targets, including muscarinic receptor or P2X1-purinoceptor antagonists, are potentially effective treatment options for benign prostatic hyperplasia (BPH), according to a review published online June 8 in the British Journal of Pharmacology.

Abstract
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Limited Formalin Exposure May Impair Disease Diagnosis

THURSDAY, June 23 (HealthDay News) -- Limited exposure to formalin may impair the immunogenicity of some biopsy specimens for select diseases, according to a study published in the July issue of the Journal of the American Academy of Dermatology.

Abstract
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Syndrome Caused by E. coli Mostly in Adults, Women

WEDNESDAY, June 22 (HealthDay News) -- A large, ongoing outbreak of the hemolytic-uremic syndrome caused by Shiga-toxin-producing Escherichia coli (E. coli) in Germany is occurring mostly in adults, primarily women, according to a study published online June 22 in the New England Journal of Medicine.

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Increased Prevalence of Diabetic Kidney Disease

WEDNESDAY, June 22 (HealthDay News) -- The prevalence of diabetic kidney disease (DKD) in the United States increased between 1988 and 2008 in proportion to the prevalence of diabetes, according to a study published online June 22/29 in the Journal of the American Medical Association.

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Perinatal Exposures May Impact Breast Development

WEDNESDAY, June 22 (HealthDay News) -- Gestational or perinatal exposure to certain endocrine-disrupting chemicals (EDCs) can alter mammary gland (MG) development, disrupt lactation, and increase susceptibility to breast cancer, according to a review published online June 22 in Environmental Health Perspectives.

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Insufficient Evidence for Pretesting TPMT Status

WEDNESDAY, June 22 (HealthDay News) -- There is insufficient evidence to support pretesting for thiopurine S-methyltransferase (TPMT) status before initiating thiopurine treatment, and estimates of the sensitivity of genotyping are imprecise, according to a review published in the June 21 issue of the Annals of Internal Medicine.

Abstract
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Editorial (subscription or payment may be required)

Intensive-Dose Statins Linked to Increased Diabetes Risk

TUESDAY, June 21 (HealthDay News) -- Intensive-dose statin therapy may be associated with an increased risk of new-onset diabetes and a lower risk of cardiovascular events, according to a meta-analysis published in the June 22/29 issue of the Journal of the American Medical Association.

Abstract
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Multidetector CT Scan Diagnostic of Appendicitis

TUESDAY, June 21 (HealthDay News) -- Multidetector computed tomography (MDCT) is a highly sensitive and specific test for routine evaluation of suspected appendicitis in adults, according to a study published in the June 21 issue of the Annals of Internal Medicine.

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Guideline-Concordance High for Surgical Cancer Patients

TUESDAY, June 21 (HealthDay News) -- The guideline-concordance levels are mainly high in surgical oncology care, but are lower in certain areas, including nodal management, according to a study published online June 20 in the Archives of Surgery.

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Mice Study: Viral-Expressed cDNA Library May Treat Cancer

MONDAY, June 20 (HealthDay News) -- Viral-expressed complementary DNA (cDNA) libraries may offer a novel way of treating cancer, according to an experimental study published online June 19 in Nature Medicine.

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U.S. Food Allergy Prevalence Higher Than Reported

MONDAY, June 20 (HealthDay News) -- The prevalence and severity of childhood food allergy in the United States is greater than previously reported, with disparities in childhood allergy and its clinical diagnosis, according to a study published online June 20 in Pediatrics.

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Newly Described Processes Limit Post-Ischemia Epithelial Damage

MONDAY, June 20 (HealthDay News) -- The epithelial lining of human jejunum is preserved during intestinal ischemia-reperfusion (IR) by rapid lamina propria contraction and zipper-like constriction of epithelial cells before they are shed into the lumen, according to a study published in the July issue of the Journal of Pathology.

Abstract
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Inconsistent Thresholds Seen in CT, MR Perfusion Imaging

MONDAY, June 20 (HealthDay News) -- Optimum values for cerebral perfusion imaging with computed tomography (CT) or magnetic resonance (MR) to identify tissue at risk of infarction in acute stroke are not consistent, according to a review published online June 2 in the Annals of Neurology.

Abstract
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NAT Screening May Lower Undetected Hep C in Donors

MONDAY, June 20 (HealthDay News) -- Nucleic acid testing (NAT) screening for hepatitis C virus (HCV) in organ donors may be more effective than serology alone for detecting infection during the window period, according to a study published in the June issue of the American Journal of Transplantation.

Abstract
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Low Risk of Malignant Progression in Barrett's

FRIDAY, June 17 (HealthDay News) -- The risk of malignant progression for patients with Barrett's esophagus (BE) may be lower than previously reported, according to a study published online June 16 in the Journal of the National Cancer Institute.

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Donor-Derived Lymphomas Mostly Develop in Allograft

FRIDAY, June 17 (HealthDay News) -- The majority of post-transplant lymphoproliferative disorders (PTLDs) that are localized in the allograft are of donor origin and are diagnosed earlier, according to a study published in the June issue of the American Journal of Transplantation.

Abstract
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Reduction in Cancer Mortality Not Evenly Distributed

FRIDAY, June 17 (HealthDay News) -- There has been a steady decline in overall cancer death rates in the United States from 1990 to 2007, but this decline has not affected all segments of the population, according to the American Cancer Society Cancer Statistics 2011 report published online June 17 in CA: A Cancer Journal for Clinicians.

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HPV Vaccination Program Tied to Fewer Cervical Abnormalities

FRIDAY, June 17 (HealthDay News) -- The incidence of high-grade cervical abnormalities (HGAs) has decreased in girls younger than 18 years, within three years of the implementation of a population-wide human papillomavirus (HPV) vaccination program in Australia, according to a review published in the June 18 issue of The Lancet.

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Syphilis Screening May Reduce Adverse Pregnancy Outcomes

THURSDAY, June 16 (HealthDay News) -- Screening interventions may reduce the incidence of perinatal death and stillbirth attributed to syphilis, according to a review published online June 16 in The Lancet Infectious Diseases.

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Gene Mutation Tied to Increased Vitamin D Sensitivity

THURSDAY, June 16 (HealthDay News) -- Mutations in CYP24A1 are associated with increased sensitivity to vitamin D in patients with idiopathic infantile hypercalcemia, and may be a potential genetic risk factor for the development of symptomatic hypercalcemia in otherwise healthy infants, according to a study published online June 15 in the New England Journal of Medicine.

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Infectious Patients on Flights May Raise Influenza Risk

THURSDAY, June 16 (HealthDay News) -- Influenza-like illness (ILI) may be transmitted during a flight, with disease incidence being clustered closely around a passenger who was symptomatic or infectious during the flight, according to a study published online June 16 in Emerging Infectious Diseases.

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Increased Risk of Femoral Arterial Thrombosis in Children

THURSDAY, June 16 (HealthDay News) -- For children with indwelling arterial catheters (IACs), the incidence of arterial thrombosis is increased in the femoral artery and is independently associated with age, according to a study published in the June issue of the Journal of Thrombosis and Haemostasis.

Abstract
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New Meningococcal A Conjugate Vaccine Is Effective

WEDNESDAY, June 15 (HealthDay News) -- A new meningococcal A (MenA) conjugate vaccine (PsA-TT) has been found to have a stronger antibody response to group A meningococci than a quadrivalent polysaccharide reference vaccine (PsACWY), according to a study published in the June 16 issue of the New England Journal of Medicine.

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Increased Recurrent Stroke Risk in Type 2 Diabetes

WEDNESDAY, June 15 (HealthDay News) -- Patients enrolled in the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial who have type 2 diabetes may have increased incidence of recurrent stroke and cardiovascular events, but the effect of atorvastatin treatment is independent of whether the patients have type 2 diabetes, or metabolic syndrome (MetS), according to a study published online June 13 in the Archives of Neurology.

Abstract
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Life Expectancy in U.S. Counties Below Many Nations

WEDNESDAY, June 15 (HealthDay News) -- Most counties within the United States fall behind the international frontier with the best life expectancies in the world, according to a study published online June 15 in Population Health Metrics.

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FGF-23 Linked to End-Stage Renal Disease and Death

WEDNESDAY, June 15 (HealthDay News) -- In patients with chronic kidney disease, elevated fibroblast growth factor 23 (FGF-23) is associated with end-stage renal disease and death, according to a study published in the June 15 issue of the Journal of the American Medical Association.

Abstract
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FDA OKs Test to Spot HER2-Positive Breast Cancer

TUESDAY, June 14 (HealthDay News) -- The U.S. Food and Drug Administration has approved the Inform Dual ISH test, a genetic test to determine whether women with breast cancer are human epidermal growth factor receptor (HER)2-positive and therefore candidates for trastuzumab (Herceptin).

More Information

Similar Number for Outpatient, Inpatient Malpractice Claims

TUESDAY, June 14 (HealthDay News) -- The number of paid malpractice claims is similar in both inpatient and outpatient settings, according to a study published in the June 15 issue of the Journal of the American Medical Association.

Abstract
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Lengthy TV Viewing Tied to Increased Morbidity, Mortality

TUESDAY, June 14 (HealthDay News) -- Prolonged television viewing is associated with an increased risk of developing type 2 diabetes, fatal or nonfatal cardiovascular disease, and all-cause mortality, according to a meta-analysis published in the June 15 issue of the Journal of the American Medical Association.

Abstract
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High Folate Levels Don't Worsen B12 Deficiency Effects

TUESDAY, June 14 (HealthDay News) -- Biochemical abnormalities related to B12 deficiency may not be exacerbated by high folate concentrations, according to a study published online June 8 in The American Journal of Clinical Nutrition.

Abstract
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Low Fat, Glycemic Index Diet May Reduce Alzheimer's Risk

TUESDAY, June 14 (HealthDay News) -- Following a diet low in saturated fat and with a low glycemic index may positively impact biomarkers of Alzheimer's disease for healthy individuals and those with amnestic mild cognitive impairment (aMCI), according to a study published in the June issue of the Archives of Neurology.

Abstract
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Mobile Phone Users May Have Increased Glioma Risk

MONDAY, June 13 (HealthDay News) -- The mobile phone radio frequency (RF) energy dose absorbed at a tumor location depends on tumor location, phone type, network properties, and conditions of use, and individuals with high mobile phone use may have an increased risk of gliomas in the most exposed areas of the brain, according to two studies published online June 9 in Occupational & Environmental Medicine.

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New Device Performs PET, MRI Scans Simultaneously

FRIDAY, June 10 (HealthDay News) -- The first device to perform simultaneous position emission tomography and magnetic resonance imaging scans has been approved by the U.S. Food and Drug Administration, the agency said Friday.

PET scans and MRIs

New Diagnostic Strategy for Patients With Suspected PE

FRIDAY, June 10 (HealthDay News) -- A proposed diagnostic strategy combines clinical assessment, D-dimer testing, ultrasonography, and lung scan to give a noninvasive diagnosis for the majority of outpatients with suspected pulmonary embolism (PE), according to a study published in the June issue of Chest.

Abstract
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Reduction in Body Mass May Improve Hypothalamic Activity

THURSDAY, June 9 (HealthDay News) -- Massive reduction in the body mass of obese individuals may improve hypothalamic dysfunctional activity, as detected by functional magnetic resonance imaging (fMRI), and may increase anti-inflammatory activity in the cerebrospinal fluid (CSF), according to a study published in the June issue of Diabetes.

Abstract
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Novel Loci Tied to Fasting Glucose Levels in Children

THURSDAY, June 9 (HealthDay News) -- Novel fasting glucose loci previously identified in adults may be associated with altered fasting glucose levels in healthy children and adolescents, according to a review published in the June issue of Diabetes.

Abstract
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Rare Gene Copy Number Variations Linked to Autism

THURSDAY, June 9 (HealthDay News) -- Autism spectrum disorder (ASD) is associated with the presence of rare de novo copy number variants (CNV), according to three studies published in the June issue of Neuron.

Abstract - Sanders
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Gene Mutation Links Hormone Resistance, Acrodysostosis

WEDNESDAY, June 8 (HealthDay News) -- A germ-line mutation found within the cyclic adenosine monophosphate (cAMP) signaling pathway may explain the association between congenital bone dysplasia and resistance to several hormones in patients with acrodysostosis, according to a study published online June 9 in the New England Journal of Medicine.

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Daily Activities Impacted by Cognitive Impairment

WEDNESDAY, June 8 (HealthDay News) -- Mild deficits in instrumental activities of daily living (IADLs) are common in individuals with amnestic mild cognitive impairment (aMCI), according to a study published in the June issue of the Archives of General Psychiatry.

Abstract
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CDC: Incidence of Several Foodborne Infections Declines

TUESDAY, June 7 (HealthDay News) -- Although the incidence of several foodborne infections -- including Shiga toxin-producing Escherichia coli (STEC) O157 -- has declined over the past several years, the incidence of Salmonella infection has not decreased, according to a Vital Signs report in the June 7 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Late-Onset GI Complications Tied to Childhood Cancers

MONDAY, June 6 (HealthDay News) -- Survivors of childhood cancer have an increased risk of developing gastrointestinal (GI) complications later in life, according to a study published in the May issue of Gastroenterology.

Abstract
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Appendectomy, Tonsillectomy May Increase AMI Risk

FRIDAY, June 3 (HealthDay News) -- Youth who undergo appendectomy or tonsillectomy before age 20 may have an increased risk of acute myocardial infarction (AMI) later in life, according to a study published online June 1 in the European Heart Journal.

Abstract
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New MRSA Strain Detected in Cow's Milk

FRIDAY, June 3 (HealthDay News) -- Researchers have identified a novel methicillin-resistant Staphylococcus aureus (MRSA) strain in cow's milk that is genetically different from existing MRSA strains; their research has been published online June 3 in The Lancet Infectious Diseases.

Abstract
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Molecular Mechanisms of Priapism Identified

FRIDAY, June 3 (HealthDay News) -- Recent advances have identified several molecular mechanisms, which may play a role in sickle cell disease-associated priapism, according to a review published online May 6 in The Journal of Sexual Medicine.

Abstract
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Winter Conception Associated With Higher Autism Risk

THURSDAY, June 2 (HealthDay News) -- Children conceived during winter months may be at higher risk for developing autism than children conceived in the summer, according to research published online May 3 in Epidemiology.

Abstract
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Fear of Dying Tied to TNFα Levels in Cardiac Injury

THURSDAY, June 2 (HealthDay News) -- Fear of dying is seen in most patients with acute coronary syndrome (ACS) and is correlated with inflammatory responses, according to a study published online June 1 in the European Heart Journal.

Abstract
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Maternal and Placental Size Linked to Men's Heart Disease

THURSDAY, June 2 (HealthDay News) -- Three combinations of maternal body size and placental size can predict coronary heart disease in men, according to a study published online June 1 in the European Heart Journal.

Abstract
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Bovine Serum Albumin Linked to Membranous Nephropathy

THURSDAY, June 2 (HealthDay News) -- Some patients with childhood membranous nephropathy have circulating bovine serum albumin and anti-bovine serum antibodies, which co-localize to form immune deposits, according to a study published in the June 2 issue of the New England Journal of Medicine.

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PCR Assay Useful for Early Detection of CMV in Infants

THURSDAY, June 2 (HealthDay News) -- Real-time polymerase chain reaction (PCR) assays of both liquid- and dried-saliva specimens may represent a useful diagnostic tool for the detection of cytomegalovirus (CMV) infections in newborns, according to a study published in the June 2 issue of the New England Journal of Medicine.

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Murine Viruses Not Linked to Human Infection

WEDNESDAY, June 1 (HealthDay News) -- Murine-like gammaretroviruses (MLVs), including xenotropic murine leukemia virus-related virus (XMRV), are unlikely to cause either prostate cancer or chronic fatigue syndrome (CFS) in humans, and their detection in human beings is likely due to sample contamination, according to two studies published online May 31 in Science.

Abstract - Paprotka
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Clinical Correlates Found for Steatohepatosis Progression

WEDNESDAY, June 1 (HealthDay News) -- Most patients with nonalcoholic steatohepatosis (NASH) who develop hepatocellular carcinoma (HCC) are male and have high rates of obesity, diabetes, and hypertension, according to a study published in the May issue of Clinical Gastroenterology and Hepatology.

Abstract
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Omental Adipocyte Hypertrophy Tied to Lipid Profile

WEDNESDAY, June 1 (HealthDay News) -- In women, omental, but not subcutaneous, adipocyte hypertrophy is correlated with an altered lipid profile, including hypertriglyceridemia, according to a study published in the May issue of Diabetes.

Abstract
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Functional MRI May Indicate Language Disability in Autism

WEDNESDAY, June 1 (HealthDay News) -- Functional magnetic resonance imaging (fMRI) may be used as an indicator of language impairment in children with autism, according to a study published online May 31 in Radiology.

Abstract
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Beta Blockers May Benefit Breast Cancer Patients

WEDNESDAY, June 1 (HealthDay News) -- In patients with breast cancer, beta-blockers may reduce disease progression and mortality as well as improve relapse-free survival, according to two studies published online May 31 in the Journal of Clinical Oncology.

Abstract - Barron
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Abstract - Melhem-Bertrandt
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