August 2011 Briefing - DermatologyLast Updated: September 01, 2011.
Here are what the editors at HealthDay consider to be the most important developments in Dermatology for August 2011. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Loss of Jobs Means Loss of Health Coverage for Many in U.S.
MONDAY, Aug. 29 (HealthDay News) -- For American adults who lose their health insurance coverage when they lose their jobs, the majority remain uninsured, delay getting needed health care or prescriptions, and report financial difficulties paying medical bills, according to a report published online Aug. 24 by The Commonwealth Fund.
Exclusive Breast-Feeding Doesn't Lower Eczema Risk
MONDAY, Aug. 29 (HealthDay News) -- There is no evidence that exclusive breast-feeding for four or more months provides protection against childhood eczema, according to a study published online Aug. 24 in the British Journal of Dermatology.
Complementary Medicine Used More by Health Care Workers
FRIDAY, Aug. 26 (HealthDay News) -- U.S. health care workers, especially health care providers, are more likely to use complementary and alternative medicine (CAM) than the general, employed U.S. population, according to a study published online Aug. 22 in Health Services Research.
Pharmaceutical Ads Often Don't Adhere to U.S. FDA Guidelines
THURSDAY, Aug. 25 (HealthDay News) -- Physician-targeting pharmaceutical advertisements have low rates of adherence to U.S. Food and Drug Administration (FDA) guidelines and provide inadequate information for safe prescribing, according to a study published online Aug. 17 in PLoS One.
Biologic Therapies for Psoriasis Do Not Up CV Risk
TUESDAY, Aug. 23 (HealthDay News) -- Biologic therapies anti-interleukin (IL)-12 and IL-23 [anti-IL-12/23] and anti-tumor necrosis factor α (TNF-α) in patients with chronic plaque psoriasis (CPP) do not increase the risk of major adverse cardiovascular events (MACEs), according to a meta-analysis published online Aug. 24 in the Journal of the American Medical Association.
CDC: 2010/2011 Flu Vaccination Coverage Studied
THURSDAY, Aug. 18 (HealthDay News) -- Influenza vaccination coverage among health care personnel (HCP) and pregnant women in the 2010/2011 influenza season was similar to coverage for the 2009/2010 season, according to two reports in the Aug. 19 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.
High Cumulative Malpractice Risk for All Physicians
THURSDAY, Aug. 18 (HealthDay News) -- Physicians in all specialties have a high cumulative risk of facing a malpractice claim by age 65; although most claims do not lead to indemnity payments, according to a study published in the Aug. 18 issue of the New England Journal of Medicine.
IL-36-Receptor Antagonist Tied to Pustular Psoriasis
WEDNESDAY, Aug. 17 (HealthDay News) -- Generalized pustular psoriasis is associated with mutated interleukin-36-receptor antagonist (interleukin-36Ra) structure and unregulated production of inflammatory cytokines, according to a study published in the Aug. 18 issue of the New England Journal of Medicine.
New Drug Approved for Advanced Skin Cancer
WEDNESDAY, Aug. 17 (HealthDay News) -- Zelboraf (vemurafenib) has been approved by the U.S. Food and Drug Administration to treat a certain form of metastatic (spreading) melanoma, or cases that cannot be removed surgically, the agency said Wednesday.
High Vitamin D Levels Up Nonmelanoma Skin Cancer Risk
WEDNESDAY, Aug. 17 (HealthDay News) -- Higher baseline serum 25-hydroxyvitamin D (25-OHD) levels are significantly and positively associated with an increased risk of nonmelanoma skin cancer (NMSC), according to a study published online Aug. 15 in the Archives of Dermatology.
New Pressure Device Safe, Effective For Auricular Keloids
WEDNESDAY, Aug. 17 (HealthDay News) -- Overnight use of a new pressure device as an adjuvant therapy for the treatment of auricular keloids is safe and effective, with the potential for prophylaxis of recurrence, according to a study published online Aug. 15 in the Archives of Facial Plastic Surgery.
Diabetic Dermopathy Tied to Abnormal Skin Blood Flow
WEDNESDAY, Aug. 17 (HealthDay News) -- The pretibial surfaces of the legs of patients with diabetic dermopathy have significantly lower skin blood flow on normal-appearing skin than in control patients, whereas dermopathy lesions have higher blood flow, according to a study published in the September issue of the Journal of the American Academy of Dermatology.
Prolonged Tetracycline for Acne Lowers S. aureus Colonization
WEDNESDAY, Aug. 17 (HealthDay News) -- In patients with acne, the prolonged use of tetracycline antibiotics lowers the prevalence of colonization by Staphylococcus aureus (S. aureus) and does not increase resistance to tetracycline antibiotics, according to a study published in the August issue of the Archives of Dermatology.
UVR Exposure From Tanning Beds Ups Cerebral Blood Flow
MONDAY, Aug. 15 (HealthDay News) -- Exposure to ultraviolet radiation (UVR) during use of a tanning bed increases regional cerebral blood flow (rCBF) in the dorsal striatum, anterior insula, and medial orbitofrontal cortex, according to a study published online April 11 in Addiction Biology.
Clindamycin More Effective in Treating Soft Tissue Infections
MONDAY, Aug. 15 (HealthDay News) -- Use of trimethoprim-sulfamethoxazole and β-lactams for treatment of pediatric skin and soft tissue infections (SSTIs) is associated with increased risks of treatment failure and recurrence compared to treatment with clindamycin, according to a study published online Aug. 15 in Pediatrics.
Vitamin D Deficiency, Gene Polymorphisms Up Food Sensitivity
FRIDAY, Aug. 12 (HealthDay News) -- Vitamin D deficiency (VDD) increases the risk of food sensitization (FS) in children with certain single-nucleotide polymorphisms (SNPs), specifically in IL4, according to a study published online Aug. 5 in Allergy.
CDC: M. haemophilum Infection Possible After Tattooing
THURSDAY, Aug. 11 (HealthDay News) -- Mycobacterium haemophilum (M. haemophilum) infection has been identified in at least one immunocompetent adult with a chronic skin infection after tattooing, according to a study published online Aug. 10 in the U.S. Centers for Disease Control and Prevention's Emerging Infectious Diseases.
Environmental Factors Tied to Psoriatic Arthritis Development
WEDNESDAY, Aug. 10 (HealthDay News) -- Environmental factors, including infections that require antibiotic treatment, injuries, and occupations that involved lifting heavy weights, are significantly associated with the development of psoriatic arthritis (PsA), according to a study published in the August issue of Arthritis Care & Research.
Cost of Interacting With Payers Higher in U.S. Than Canada
FRIDAY, Aug. 5 (HealthDay News) -- Physician practices in the United States spend considerably more on interactions with health plans than Canadian practices, according to a study published in the August issue of Health Affairs.
Mechanisms for Allergic Contact Dermatitis Elucidated
FRIDAY, Aug. 5 (HealthDay News) -- Chemical modifications of proteins, and activation of toll-like receptors (TLR2 and TLR4) in the skin are some of the processes involved in activation of innate effector mechanisms and signaling pathways in allergic contact dermatitis (ACD), according to a study published in the September issue of Allergy.
Cetuximab Effective, Safe for Squamous Cell Skin Carcinoma
TUESDAY, Aug. 2 (HealthDay News) -- In patients with unresectable squamous cell carcinoma of the skin (SCCS), first-line treatment with single-agent cetuximab has an overall disease control rate (DCR) of 69 percent, according to a study published online Aug. 1 in the Journal of Clinical Oncology.