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Category: Endocrinology | Monthly Briefing

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August 2011 Briefing - Diabetes & Endocrinology

Last Updated: September 01, 2011.

 

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Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for August 2011. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Electronic Records Tied to Better Diabetes Care, Outcomes

WEDNESDAY, Aug. 31 (HealthDay News) -- Medical practices using electronic health records (EHRs) achieve significantly higher composite standards for diabetes care and outcomes than those using paper records, according to a study published in the Sept. 1 issue of the New England Journal of Medicine.

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Rate of Maternal Weight Gain Impacts Size of Neonate

WEDNESDAY, Aug. 31 (HealthDay News) -- Greater than recommended rates of weight gain during the second and third trimesters increase the odds of large-for-gestational-age babies regardless of prepregnancy maternal body mass index (BMI), and gaining at a lower than recommended rate increases the odds of small-for-gestational age babies for all except the most obese women, according to a study published in the September issue of Obstetrics & Gynecology.

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Metabolic Syndrome Linked to Chronic Kidney Disease Risk

TUESDAY, Aug. 30 (HealthDay News) -- Metabolic syndrome (MetS) and its components are significantly associated with the development of estimated glomerular filtration rates (eGFR) less than 60 ml/min/1.73 m², according to a meta-analysis published online Aug. 18 in the Clinical Journal of the American Society of Nephrology.

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Child-Care Settings Opportunity to Prevent Childhood Obesity

TUESDAY, Aug. 30 (HealthDay News) -- Child-care settings can offer numerous opportunities for healthy eating and physical activity to prevent childhood obesity, but few interventions have been designed to address these issues, according to a review published online Aug. 26 in the Journal of the American Dietetic Association.

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Aerobic Training Better Than Resistance Training for Obese

TUESDAY, Aug. 30 (HealthDay News) -- For sedentary, overweight and obese adults, aerobic training (AT) is more effective than resistance training (RT) at reducing visceral fat, total abdominal fat, liver fat, alanine aminotransferase (ALT) levels, and fasting insulin resistance (HOMA), and there is no additional benefit of adding RT to AT, according to a study published online Aug. 16 in the American Journal of Physiology - Endocrinology and Metabolism.

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Public Sector Funds Large Part of State Obesity-Related Costs

MONDAY, Aug. 29 (HealthDay News) -- Between 22 and 55 percent of U.S. state-level obesity-related costs are financed by the public sector via Medicare and Medicaid, according to a study published online June 16 in Obesity.

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Age, Income Tied to Youth Adherence to ADA Guidelines

MONDAY, Aug. 29 (HealthDay News) -- Overall adherence of youth to the American Diabetes Association (ADA) testing guidelines is good and is correlated with age and family income, with older age and lower income associated with non-adherence, according to a study published online Aug. 22 in Pediatrics.

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Loss of Jobs Means Loss of Health Coverage for Many in U.S.

MONDAY, Aug. 29 (HealthDay News) -- For American adults who lose their health insurance coverage when they lose their jobs, the majority remain uninsured, delay getting needed health care or prescriptions, and report financial difficulties paying medical bills, according to a report published online Aug. 24 by The Commonwealth Fund.

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Obesity Epidemic Increasing Worldwide

FRIDAY, Aug. 26 (HealthDay News) -- Obesity appears to be increasing worldwide, affecting countries in varying degrees and negatively impacting quality of life and increasing associated societal costs, however, a new weight loss model and national government intervention may help slow and reverse the epidemic, according to four studies published in an obesity series online August 25 in The Lancet.

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Complementary Medicine Used More by Health Care Workers

FRIDAY, Aug. 26 (HealthDay News) -- U.S. health care workers, especially health care providers, are more likely to use complementary and alternative medicine (CAM) than the general, employed U.S. population, according to a study published online Aug. 22 in Health Services Research.

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Pharmaceutical Ads Often Don't Adhere to U.S. FDA Guidelines

THURSDAY, Aug. 25 (HealthDay News) -- Physician-targeting pharmaceutical advertisements have low rates of adherence to U.S. Food and Drug Administration (FDA) guidelines and provide inadequate information for safe prescribing, according to a study published online Aug. 17 in PLoS One.

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Hospitalization Ups Unintentional Discontinuation of Meds

TUESDAY, Aug. 23 (HealthDay News) -- Hospital or intensive care unit (ICU) admission is associated with unintentional discontinuation of medication for chronic diseases, according to a study published online Aug. 23 in the Journal of the American Medical Association.

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Dietary Portfolio Significantly Lowers LDL-C in Hyperlipidemia

TUESDAY, Aug. 23 (HealthDay News) -- Patients with hyperlipidemia using a specific dietary portfolio at different levels of intensity have greater reductions in low-density lipoprotein cholesterol (LDL-C) during six months of follow-up than those receiving low-saturated fat dietary advice, according to a study published Aug. 24/31 in the Journal of the American Medical Association.

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Mobile Phone-Based System Tied to Lower Glycated Hemoglobin

MONDAY, Aug. 8 (HealthDay News) -- A mobile phone-based treatment/behavioral coaching program significantly improves glycated hemoglobin levels over 12 months in patients with type 2 diabetes, according to a study published online July 25 in Diabetes Care.

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Diabetes, Hypertension Up Risk for Open-Angle Glaucoma

MONDAY, Aug. 22 (HealthDay News) -- Components of metabolic syndrome, including diabetes mellitus (DM) and systemic arterial hypertension (HTN) either alone or in combination, are associated with higher risk of open-angle glaucoma (OAG); whereas, the presence of hyperlipidemia lowers the risk, according to a study published in the July issue of Ophthalmology.

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Omega-3 Cost-Effective for Hypertriglyceridemia

MONDAY, Aug. 22 (HealthDay News) -- A validated model indicates that prescription ω-3 fatty acids (P-OM3) offer cost-effective reduction of adverse cardiac events and triglyceride levels in patients with severe (≥500 mg/dL) hypertriglyceridemia (SHTG), according to a study published in the Sept. 1 issue of The American Journal of Cardiology.

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Peak Brown Adipose Tissue Activity Seen in Adolescence

FRIDAY, Aug. 19 (HealthDay News) -- Peak brown adipose tissue (BAT) activity occurs in adolescence among both boys and girls and is inversely associated with body mass index (BMI)-percentile, according to a study published online Aug. 12 in The Journal of Pediatrics.

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Traditional Risk Factors Up Early RA Cardiovascular Events

FRIDAY, Aug. 19 (HealthDay News) -- Traditional cardiovascular (CV) risk factors increase the risk of new cardiovascular events (CVEs) in patients with rheumatoid arthritis (RA), with disease activity increasing the risk, and treatment with disease modifying antirheumatic drugs (DMARDs) decreasing the risk, according to a study published online Aug. 15 in Arthritis Research & Therapy.

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Excess Body Fat in Elderly Tied to Decreased Life Expectancy

FRIDAY, Aug. 19 (HealthDay News) -- Excess body fat, as measured by body mass index (BMI), in elderly adults older than 75 years is associated with decreased life expectancy, according to a study published in the June issue of the Journal of the American Geriatrics Society.

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CDC: 2010/2011 Flu Vaccination Coverage Studied

THURSDAY, Aug. 18 (HealthDay News) -- Influenza vaccination coverage among health care personnel (HCP) and pregnant women in the 2010/2011 influenza season was similar to coverage for the 2009/2010 season, according to two reports in the Aug. 19 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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TV Viewing Reduces Life Expectancy in Australian Adults

THURSDAY, Aug. 18 (HealthDay News) -- Television (TV) viewing time is correlated with a substantial reduction in life expectancy among Australian adults, according to a study published online Aug. 15 in the British Journal of Sports Medicine.

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High Cumulative Malpractice Risk for All Physicians

THURSDAY, Aug. 18 (HealthDay News) -- Physicians in all specialties have a high cumulative risk of facing a malpractice claim by age 65; although most claims do not lead to indemnity payments, according to a study published in the Aug. 18 issue of the New England Journal of Medicine.

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Rituximab Suppresses Autoantibodies to Insulin

THURSDAY, Aug. 18 (HealthDay News) -- Treatment with rituximab differentially suppresses autoantibodies to insulin (IAAs) in all patients with new-onset type 1A diabetes for a year, according to a study published online Aug. 10 in Diabetes.

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Fructose-Rich Corn Syrup Intake Raises CVD Risk

THURSDAY, Aug. 18 (HealthDay News) -- Consuming high-fructose corn syrup (HFCS) for two weeks at 25 percent of energy requirements (E) increases triglycerides, low-density lipoprotein (LDL), and apolipoprotein B (apoB) levels in young adults comparably to fructose but more than glucose, according to a study published online Aug. 17 in the Journal of Clinical Endocrinology & Metabolism.

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Pericardial Fat Volume Tied to Atherosclerotic Plaque Burden

WEDNESDAY, Aug. 17 (HealthDay News) -- Pericardial fat volume is more strongly associated with coronary atherosclerotic plaque burden than body mass index (BMI) or waist circumference, according to a study published online Aug. 16 in Radiology.

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Diabetic Dermopathy Tied to Abnormal Skin Blood Flow

WEDNESDAY, Aug. 17 (HealthDay News) -- The pretibial surfaces of the legs of patients with diabetic dermopathy have significantly lower skin blood flow on normal-appearing skin than in control patients, whereas dermopathy lesions have higher blood flow, according to a study published in the September issue of the Journal of the American Academy of Dermatology.

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High Vitamin D Levels Up Nonmelanoma Skin Cancer Risk

WEDNESDAY, Aug. 17 (HealthDay News) -- Higher baseline serum 25-hydroxyvitamin D (25-OHD) levels are significantly and positively associated with an increased risk of nonmelanoma skin cancer (NMSC), according to a study published online Aug. 15 in the Archives of Dermatology.

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Radioactive Iodine for Thyroid Cancer Rises From 1999 to 2008

TUESDAY, Aug. 16 (HealthDay News) -- The proportion of patients with well-differentiated thyroid cancer receiving radioactive iodine following a total thyroidectomy increased significantly from 1999 to 2008, with much of the variation in use associated with hospital characteristics, according to a study published in the Aug. 17 issue of the Journal of the American Medical Association.

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Diabetes, Islet Autoantibodies Localize to Same HLA Region

TUESDAY, Aug. 16 (HealthDay News) -- Type 1 diabetes and islet autoantibodies localize to the same human leukocyte antigen (HLA) class II genes but the effects of the alleles and associated genotypes are very different, according to a study published online Aug. 10 in Diabetes.

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Early Sulfonylureas Benefit Mice With Neonatal Diabetes

MONDAY, Aug. 15 (HealthDay News) -- For mice with neonatal diabetes mellitus (NDM) with adenosine triphosphate (ATP)-sensitive K channel mutations (KATP), early treatment with sulphonylurea therapy leads to permanent remission in approximately 30 percent of cases, according to an experimental study published online Aug. 3 in Diabetes.

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Trastuzumab Ups Cardiotoxicity Risk in Some Elderly Women

FRIDAY, Aug. 12 (HealthDay News) -- In elderly women with breast cancer and a history of cardiac disease or diabetes, treatment with trastuzumab is associated with an increased risk of cardiotoxicity, according to a study published online Aug. 9 in the Annals of Oncology.

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Soy Isoflavones Don't Prevent Menopausal Bone Loss

TUESDAY, Aug. 9 (HealthDay News) -- Soy isoflavone tablets, administered once daily, do not prevent bone loss or menopausal symptoms in women during the first five years of menopause, according to a study published in the Aug. 8/22 issue of the Archives of Internal Medicine.

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Leptin Tied to Improvements in Insulin-Deficient Mice

MONDAY, Aug. 8 (HealthDay News) -- Leptin is associated with therapeutic benefits in the long-term treatment of mice with insulin-deficient nonobese diabetes, with a reduction in the onset and progression of glucose intolerance and diabetes complications, and an improvement in longevity, according to an experimental study published online Aug. 1 in Diabetes.

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Sexual and Endothelial Function Improves With Weight Loss

MONDAY, Aug. 8 (HealthDay News) -- Weight loss induced by following a low-calorie diet (LCD) or a low-fat, high-protein, reduced-carbohydrate (HP) diet improves sexual, urinary, and inflammatory function in obese men with diabetes, according to a study published online Aug. 5 in The Journal of Sexual Medicine.

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New Score System Predicts Lower-Extremity Amputation Risk

FRIDAY, Aug. 5 (HealthDay News) -- A new scoring system that stratifies the risk of nontraumatic lower-extremity amputation (LEA) among patients hospitalized for a diabetic foot infection, has been developed and validated, according to a study published in the August issue of Diabetes Care.

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Cost of Interacting With Payers Higher in U.S. Than Canada

FRIDAY, Aug. 5 (HealthDay News) -- Physician practices in the United States spend considerably more on interactions with health plans than Canadian practices, according to a study published in the August issue of Health Affairs.

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Higher Muscle Mass Tied to Lower Pre-, Overt Diabetes Risk

FRIDAY, Aug. 5 (HealthDay News) -- Higher muscle mass relative to body size is associated with lower insulin resistance and a lower risk of prediabetes (PDM) or overt diabetes mellitus (DM), according to a study published online July 21 in the Journal of Clinical Endocrinology & Metabolism.

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Nurse Case Managers Improve Cardiac Risk Control in Diabetes

FRIDAY, Aug. 5 (HealthDay News) -- Nurse case managers can improve the percentage of patients with diabetes who achieve control of hypertension, hyperglycemia, and hyperlipidemia, according to a study published in the August issue of Diabetes Care.

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Lower Post MI Physical Activity in Areas With Low Income

THURSDAY, Aug. 4 (HealthDay News) -- Low neighborhood socioeconomic status (SES) is a significant predictor of lower uptake of leisure-time physical activity (LTPA) by survivors of myocardial infarction (MI), even after adjusting for individual SES and clinical profile, according to a study published online Aug. 2 in the American Journal of Preventive Medicine.

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Gastric Bypass Tied to Reduced Fat Intake in Humans, Rats

THURSDAY, Aug. 4 (HealthDay News) -- Gastric bypass is associated with reduced intake of and preference for fat in rats, and reduced intake of dietary fat for humans, according to an experimental study published online in July 6 in the American Journal of Physiology.

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Neurobehavioral Processes Affect Eating Behavior in Obese

TUESDAY, Aug. 2 (HealthDay News) -- Personal choices in weight control are affected by three neurobehavioral processes, including food reward, inhibitory control, and time discounting; and understanding these processes may help control obesity, according to a commentary published in the August issue of the Journal of the American Dietetic Association.

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Midlife Vascular Risk Factors Impact Structural Brain Aging

MONDAY, Aug. 1 (HealthDay News) -- Hypertension, diabetes, smoking, and obesity in midlife are associated with accelerated progression of structural brain aging, and decline in executive function a decade later, according to a study published in the Aug. 2 issue of Neurology.

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Infrastructure Tied to Most U.K. Obesity-Related Safety Events

MONDAY, Aug. 1 (HealthDay News) -- The majority of obesity-associated safety incidents reported to the United Kingdom's National Patient Safety Agency (NPSA) are related to infrastructure, and are classified as low or no harm, according to a study published online July 25 in the Postgraduate Medical Journal.

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Menopause Not Tied to Diabetes Risk for Glucose Intolerant

MONDAY, Aug. 1 (HealthDay News) -- Natural menopause is not associated with diabetes risk and does not influence response to diabetes prevention programs in women with glucose intolerance, according to a study published in the August issue of Menopause.

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