Here are what the editors at HealthDay consider to be the most important developments in Urology for August 2011. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
AAP Updates Infant/Young Child Febrile UTI Guidelines
WEDNESDAY, Aug. 31 (HealthDay News) -- The American Academy of Pediatrics (AAP) has released a technical report, "Diagnosis and Management of an Initial UTI in Febrile Infants and Young Children," detailing changes that include updated recommendations for imaging. The report was published online Aug. 28 in Pediatrics.
Public Sector Funds Large Part of State Obesity-Related Costs
MONDAY, Aug. 29 (HealthDay News) -- Between 22 and 55 percent of U.S. state-level obesity-related costs are financed by the public sector via Medicare and Medicaid, according to a study published online June 16 in Obesity.
Loss of Jobs Means Loss of Health Coverage for Many in U.S.
MONDAY, Aug. 29 (HealthDay News) -- For American adults who lose their health insurance coverage when they lose their jobs, the majority remain uninsured, delay getting needed health care or prescriptions, and report financial difficulties paying medical bills, according to a report published online Aug. 24 by The Commonwealth Fund.
Complementary Medicine Used More by Health Care Workers
FRIDAY, Aug. 26 (HealthDay News) -- U.S. health care workers, especially health care providers, are more likely to use complementary and alternative medicine (CAM) than the general, employed U.S. population, according to a study published online Aug. 22 in Health Services Research.
Pharmaceutical Ads Often Don't Adhere to U.S. FDA Guidelines
THURSDAY, Aug. 25 (HealthDay News) -- Physician-targeting pharmaceutical advertisements have low rates of adherence to U.S. Food and Drug Administration (FDA) guidelines and provide inadequate information for safe prescribing, according to a study published online Aug. 17 in PLoS One.
Botox Approved to Treat Urinary Incontinence
WEDNESDAY, Aug. 24 (HealthDay News) -- Botox (onabotulinumtoxinA) has been approved by the U.S. Food and Drug Administration to treat urinary incontinence in people with neurological conditions such as spinal cord injury and multiple sclerosis.
Incidental Screening Has No Impact on Adrenocortical CA
TUESDAY, Aug. 23 (HealthDay News) -- Detection rates and clinical outcomes in adrenocortical carcinoma (ACC) show no improvement due to incidental screening resulting from scans done for other purposes, according to a study published in the September issue of The Journal of Urology.
Sacral Neuromodulation Safe in Refractory Urge Incontinence
MONDAY, Aug. 22 (HealthDay News) -- Sacral neuromodulation is safe for refractory idiopathic urge incontinence in women, but the success rate gradually declines with only 15 percent of the patients completely continent after five years, according to a study published in the September issue of The Journal of Urology.
Testosterone Gel Ups Sexual Function in Hypogonadism
FRIDAY, Aug. 19 (HealthDay News) -- Testosterone replacement therapy (TRT) with Testim (testosterone 1 percent) topical gel for 12 months significantly increases total testosterone (TT), free testosterone (FT), and total brief male sexual function inventory (BMSFI) score in men with hypogonadism, according to a study published online Aug. 11 in The Journal of Sexual Medicine.
CDC: 2010/2011 Flu Vaccination Coverage Studied
THURSDAY, Aug. 18 (HealthDay News) -- Influenza vaccination coverage among health care personnel (HCP) and pregnant women in the 2010/2011 influenza season was similar to coverage for the 2009/2010 season, according to two reports in the Aug. 19 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.
High Cumulative Malpractice Risk for All Physicians
THURSDAY, Aug. 18 (HealthDay News) -- Physicians in all specialties have a high cumulative risk of facing a malpractice claim by age 65; although most claims do not lead to indemnity payments, according to a study published in the Aug. 18 issue of the New England Journal of Medicine.
New Study Links Smoking to Higher Bladder Cancer Risk
WEDNESDAY, Aug. 17 (HealthDay News) -- The relative risk for bladder cancer from tobacco smoking is higher than reported in previous studies, with population attributable risks (PARs) for women comparable to those for men, according to a study published Aug. 17 in the Journal of the American Medical Association.
Five SNPs Validated As Linked to Lethal Prostate Cancer
TUESDAY, Aug. 16 (HealthDay News) -- Five single nucleotide polymorphisms (SNPs) in five genes have been validated as being significantly associated with lethal prostate cancer, according to a study published online Aug. 16 in Cancer Epidemiology, Biomarkers & Prevention.
Unrealistic Functional Expectations Post-Prostatectomy
FRIDAY, Aug. 12 (HealthDay News) -- Many men have unrealistic expectations of their urinary and sexual function following prostatectomy, according to a study published in the August issue of The Journal of Urology.
Niacin Linked to Improved Erectile Function
FRIDAY, Aug. 12 (HealthDay News) -- Men with moderate to severe erectile dysfunction (ED) and dyslipidemia have significantly improved erectile function with treatment with niacin, according to a study published online Aug. 2 in The Journal of Sexual Medicine.
Interstitial Cystitis Subtypes Have Distinct Differences
THURSDAY, Aug. 11 (HealthDay News) -- In women with interstitial cystitis/painful bladder syndrome (IC/PBS), the number of comorbid diagnoses/symptoms differ substantially between the ulcerative (ULC) and nonulcerative (N-ULC) IC/PBS subtypes and controls, according to a study published in the August issue of Urology.
Sexual and Endothelial Function Improves With Weight Loss
MONDAY, Aug. 8 (HealthDay News) -- Weight loss induced by following a low-calorie diet (LCD) or a low-fat, high-protein, reduced-carbohydrate (HP) diet improves sexual, urinary, and inflammatory function in obese men with diabetes, according to a study published online Aug. 5 in The Journal of Sexual Medicine.
Cost of Interacting With Payers Higher in U.S. Than Canada
FRIDAY, Aug. 5 (HealthDay News) -- Physician practices in the United States spend considerably more on interactions with health plans than Canadian practices, according to a study published in the August issue of Health Affairs.
Fusion Transcript, PCA3 in Urine Predict Prostate Cancer Risk
FRIDAY, Aug. 5 (HealthDay News) -- A urine test that detects the presence of a fusion transcript of transmembrane protease, serine 2 (TMPRSS2) and v-ets erythroblastosis virus E26 oncogene homolog (avian) (ERG) genes can predict the risk of prostate cancer in men with elevated serum prostate-specific antigen (PSA), according to a study published in the Aug. 3 issue of Science Translational Medicine.
Prognostic Value of p53 in Early Urothelial Cancers Unconfirmed
WEDNESDAY, Aug. 3 (HealthDay News) -- In patients with pT1/T2N0M0 urothelial bladder cancer, the predictive value of p53 and the benefit of methotrexate, vinblastine, doxorubicin, and cisplatin (MVAC) adjuvant chemotherapy could not be demonstrated, according to a study published online Aug. 1 in the Journal of Clinical Oncology.
Alternative DHT Synthesis Pathway Key in Prostate Cancer
MONDAY, Aug. 1 (HealthDay News) -- Dihydrotestosterone (DHT) synthesis from adrenal precursor steroids in castration-resistant prostate cancer (CRPC) bypasses testosterone synthesis, and occurs through an alternative pathway involving conversion of Δ4-androstenedione (AD) to 5α-androstanedione (5α-dione) by 5α-reductase isoenzyme-1 (SRD5A1), according to an experimental study published online July 27 in the Proceedings of the National Academy of Sciences.
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