Here are what the editors at HealthDay consider to be the most important developments in Nephrology for August 2011. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
AAP Updates Infant/Young Child Febrile UTI Guidelines
WEDNESDAY, Aug. 31 (HealthDay News) -- The American Academy of Pediatrics (AAP) has released a technical report, "Diagnosis and Management of an Initial UTI in Febrile Infants and Young Children," detailing changes that include updated recommendations for imaging. The report was published online Aug. 28 in Pediatrics.
Metabolic Syndrome Linked to Chronic Kidney Disease Risk
TUESDAY, Aug. 30 (HealthDay News) -- Metabolic syndrome (MetS) and its components are significantly associated with the development of estimated glomerular filtration rates (eGFR) less than 60 ml/min/1.73 m², according to a meta-analysis published online Aug. 18 in the Clinical Journal of the American Society of Nephrology.
Public Sector Funds Large Part of State Obesity-Related Costs
MONDAY, Aug. 29 (HealthDay News) -- Between 22 and 55 percent of U.S. state-level obesity-related costs are financed by the public sector via Medicare and Medicaid, according to a study published online June 16 in Obesity.
Loss of Jobs Means Loss of Health Coverage for Many in U.S.
MONDAY, Aug. 29 (HealthDay News) -- For American adults who lose their health insurance coverage when they lose their jobs, the majority remain uninsured, delay getting needed health care or prescriptions, and report financial difficulties paying medical bills, according to a report published online Aug. 24 by The Commonwealth Fund.
Complementary Medicine Used More by Health Care Workers
FRIDAY, Aug. 26 (HealthDay News) -- U.S. health care workers, especially health care providers, are more likely to use complementary and alternative medicine (CAM) than the general, employed U.S. population, according to a study published online Aug. 22 in Health Services Research.
Pharmaceutical Ads Often Don't Adhere to U.S. FDA Guidelines
THURSDAY, Aug. 25 (HealthDay News) -- Physician-targeting pharmaceutical advertisements have low rates of adherence to U.S. Food and Drug Administration (FDA) guidelines and provide inadequate information for safe prescribing, according to a study published online Aug. 17 in PLoS One.
CDC: Reporting Delays Occurred in German E. coli Outbreak
THURSDAY, Aug. 25 (HealthDay News) -- During the outbreak of hemolytic uremic syndrome (HUS) and bloody diarrhea related to shiga toxin-producing Escherichia coli O104:H4 (STEC) in Germany during May and June 2011, there was a median delay of 20 days between symptom onset and reporting the cases, according to a study published in the U.S. Centers for Disease Control and Prevention's October Emerging Infectious Diseases.
High Serum Phosphate Tied To Renal Disease Progression
WEDNESDAY, Aug. 24 (HealthDay News) -- Serum phosphate is an independent risk factor for progression of renal disease in patients with proteinuric chronic kidney disease (CKD) and may reduce the renoprotective effect of ACE inhibitors, according to a study published online Aug. 18 in the Journal of the American Society of Nephrology.
Incidental Screening Has No Impact on Adrenocortical CA
TUESDAY, Aug. 23 (HealthDay News) -- Detection rates and clinical outcomes in adrenocortical carcinoma (ACC) show no improvement due to incidental screening resulting from scans done for other purposes, according to a study published in the September issue of The Journal of Urology.
Donor-Specific Antibody Tied to Renal Graft Rejection Risk
FRIDAY, Aug. 19 (HealthDay News) -- The presence of donor-specific antibody (DSA) increases the risk of antibody-mediated rejection (AMR) and cell-mediated rejection (CMR) of kidney allografts, according to a study published online Aug. 3 in the American Journal of Transplantation.
CDC: 2010/2011 Flu Vaccination Coverage Studied
THURSDAY, Aug. 18 (HealthDay News) -- Influenza vaccination coverage among health care personnel (HCP) and pregnant women in the 2010/2011 influenza season was similar to coverage for the 2009/2010 season, according to two reports in the Aug. 19 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.
High Cumulative Malpractice Risk for All Physicians
THURSDAY, Aug. 18 (HealthDay News) -- Physicians in all specialties have a high cumulative risk of facing a malpractice claim by age 65; although most claims do not lead to indemnity payments, according to a study published in the Aug. 18 issue of the New England Journal of Medicine.
Asymptomatic Microscopic Hematuria Ups Youth ESRD Risk
TUESDAY, Aug. 16 (HealthDay News) -- Young adults with persistent asymptomatic isolated microscopic hematuria have a significantly increased risk of treated end-stage renal disease (ESRD), although the incidence and absolute risk remain quite low for prolonged periods, according to a study published in the Aug. 17 issue of the Journal of the American Medical Association.
Glucocorticoid Reduces Renal Scarring After Pyelonephritis
TUESDAY, Aug. 16 (HealthDay News) -- Treatment with adjunctive oral methylprednisolone sodium phosphate (MPD) combined with antibiotics significantly reduces the occurrence and severity of renal scarring among children with acute pyelonephritis (APN), according to a study published online Aug. 15 in Pediatrics.
Five-Factor Model Can Estimate Hemodialysis Mortality Rate
FRIDAY, Aug. 12 (HealthDay News) -- Probable mortality rate in individuals undergoing hemodialysis (HD) can be estimated and stratified using a model consisting of five factors, according to a study published online Aug. 3 in the Journal of Internal Medicine.
Lower Mortality for Older Blacks Receiving Dialysis
TUESDAY, Aug. 9 (HealthDay News) -- Blacks older than 50 years who are undergoing dialysis have lower mortality compared to whites, as opposed to younger blacks who have an increased risk of death, according to a study published in the Aug. 10 issue of the Journal of the American Medical Association.
Sirolimus Regimens Do Not Improve Transplant Outcomes
MONDAY, Aug. 8 (HealthDay News) -- In renal allograft recipients, sirolimus (SRL)-based regimens have similar survival rates and Nankivell glomerular filtration rates (GFR) as regimens containing tacrolimus (TAC) and mycophenolate mofetil (MMF), but the rate of graft rejection and discontinuation due to adverse events is higher, according to a study published in the August issue of the American Journal of Transplantation.
Cost of Interacting With Payers Higher in U.S. Than Canada
FRIDAY, Aug. 5 (HealthDay News) -- Physician practices in the United States spend considerably more on interactions with health plans than Canadian practices, according to a study published in the August issue of Health Affairs.
Hyperspectral Imaging Assesses Intra-Op Hemoglobin Saturation
FRIDAY, Aug. 5 (HealthDay News) -- DLP Hyperspectral imaging (HSI) serves as a fast, noninvasive method to assess renal hemoglobin saturation parameters intraoperatively, according to a study published in the August issue of The Journal of Urology.
Pre- or Intradialytic Low BP Tied to Vascular Thrombosis
THURSDAY, Aug. 4 (HealthDay News) -- In patients on hemodialysis, frequent episodes of intradialytic hypotension and lower predialysis systolic blood pressure (BP) are associated with increased rates of vascular access thrombosis, according to a study published in the Aug. 1 issue of the Journal of the American Society of Nephrology.
Human Kidney Cells Can Generate Pluripotent Stem Cells
WEDNESDAY, Aug. 3 (HealthDay News) -- Normal human kidney mesangial cells can be genetically reprogrammed to produce kidney induced pluripotent stem (kiPS) cells, and renal tubular cells present in urine can be used to generate human induced pluripotent stem cells (iPSCs) with excellent ability to differentiate, according to two studies published in the July 1 issue of the Journal of the American Society of Nephrology.
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