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Category: Geriatrics | Monthly Briefing

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August 2011 Briefing - Geriatrics

Last Updated: September 01, 2011.

 

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Here are what the editors at HealthDay consider to be the most important developments in Geriatrics for August 2011. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Electronic Records Tied to Better Diabetes Care, Outcomes

WEDNESDAY, Aug. 31 (HealthDay News) -- Medical practices using electronic health records (EHRs) achieve significantly higher composite standards for diabetes care and outcomes than those using paper records, according to a study published in the Sept. 1 issue of the New England Journal of Medicine.

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Japan's Universal Health System Evaluated

WEDNESDAY, Aug. 31 (HealthDay News) -- The disproportionate aging population in Japan and societal influences may negatively impact the country's universal health care system, according to six articles published in a Japan series online Aug. 30 in The Lancet.

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Metabolic Syndrome Linked to Chronic Kidney Disease Risk

TUESDAY, Aug. 30 (HealthDay News) -- Metabolic syndrome (MetS) and its components are significantly associated with the development of estimated glomerular filtration rates (eGFR) less than 60 ml/min/1.73 m², according to a meta-analysis published online Aug. 18 in the Clinical Journal of the American Society of Nephrology.

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ESC: Mortality Up With High Serum Cathepsin S in Elderly

TUESDAY, Aug. 30 (HealthDay News) -- High circulating serum cathepsin S levels are associated with an increased risk of mortality in the elderly, according to a study published online Aug. 29 in the Journal of the American Medical Association, to coincide with its presentation at the European Society of Cardiology Congress 2011, held Aug. 27 to 31, in Paris, France.

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Lack of Slow Wave Sleep Ups Hypertension Risk in Older Men

TUESDAY, Aug. 30 (HealthDay News) -- The percentage of slow wave sleep (SWS) is significantly associated with incident hypertension in men aged 65 years and older, even after adjusting for confounding variables, according to a study published online Aug. 29 in Hypertension.

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Public Sector Funds Large Part of State Obesity-Related Costs

MONDAY, Aug. 29 (HealthDay News) -- Between 22 and 55 percent of U.S. state-level obesity-related costs are financed by the public sector via Medicare and Medicaid, according to a study published online June 16 in Obesity.

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Colchicine Safe, Effective Adjunct in Recurrent Pericarditis

MONDAY, Aug. 29 (HealthDay News) -- Colchicine appears to be safe and effective for the secondary prevention of recurrent pericarditis, according to a study published online first August 28 in the Annals of Internal Medicine.

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Apixaban Superior to Warfarin for Stroke Prevention in A-Fib

MONDAY, Aug. 29 (HealthDay News) -- Apixaban is superior to warfarin in lowering the risk of stroke or systemic embolism, and reduces the rate of major bleeding and mortality in patients with atrial fibrillation, according to a study published online Aug. 28 in the New England Journal of Medicine to coincide with the European Society of Cardiology Congress 2011 held Aug. 27 to 31 in Paris, France.

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Self-Efficacy Tied to Achieving Physical Activity Goals in RA

MONDAY, Aug. 29 (HealthDay News) -- For patients with rheumatoid arthritis (RA) having self-efficacy at baseline is tied to achieving physical activity goals, which has a direct effect on uality of life, according to a study published online Aug. 25 in Arthritis Care & Research.

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Extended-Release Opioid Pain Medication Approved

FRIDAY, Aug. 26 (HealthDay News) -- Nucynta ER (tapentadol extended release) has been approved by the U.S. Food and Drug Administration to treat moderate-to-severe chronic pain in adults, maker Janssen Pharmaceuticals said.

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Being Happily Married Ups Survival 15 Years Post Bypass

FRIDAY, Aug. 26 (HealthDay News) -- Married individuals, particularly those in a highly satisfying marriage, are significantly more likely to be alive 15 years after coronary artery bypass grafting (CABG), according to a study published online Aug. 22 in Health Psychology.

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Complementary Medicine Used More by Health Care Workers

FRIDAY, Aug. 26 (HealthDay News) -- U.S. health care workers, especially health care providers, are more likely to use complementary and alternative medicine (CAM) than the general, employed U.S. population, according to a study published online Aug. 22 in Health Services Research.

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Pharmaceutical Ads Often Don't Adhere to U.S. FDA Guidelines

THURSDAY, Aug. 25 (HealthDay News) -- Physician-targeting pharmaceutical advertisements have low rates of adherence to U.S. Food and Drug Administration (FDA) guidelines and provide inadequate information for safe prescribing, according to a study published online Aug. 17 in PLoS One.

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Elevated 1H MRS Metabolites Tied to Cognitive Function

THURSDAY, Aug. 25 (HealthDay News) -- For cognitively normal older adults, elevated proton magnetic resonance spectroscopy (1H MRS) metabolite choline (Cho)/creatine (Cr) ratios are associated with lower scores on cognitive tests, according to a study published online Aug. 24 in Neurology.

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Ambulatory BP Monitoring Cost-Effective Diagnostic Strategy

WEDNESDAY, Aug. 24 (HealthDay News) -- Ambulatory monitoring of blood pressure is the most cost-effective strategy for the diagnosis of hypertension, according to a study published online Aug. 24 in The Lancet.

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Azithromycin Decreases COPD Exacerbation Frequency

WEDNESDAY, Aug. 24 (HealthDay News) -- In selected patients with chronic obstructive pulmonary disorder (COPD), daily azithromycin for one year together with usual treatment decreases the frequency of exacerbations but increases the frequency of hearing decrements, according to a study published Aug. 25 in the New England Journal of Medicine.

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Botox Approved to Treat Urinary Incontinence

WEDNESDAY, Aug. 24 (HealthDay News) -- Botox (onabotulinumtoxinA) has been approved by the U.S. Food and Drug Administration to treat urinary incontinence in people with neurological conditions such as spinal cord injury and multiple sclerosis.

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Diastolic Dysfunction Ups Heart Failure Risk in Elderly

WEDNESDAY, Aug. 24 (HealthDay News) -- Left ventricular diastolic dysfunction worsens over time and with advancing age, increasing the risk of subsequent heart failure, according to a study published in the Aug. 24/31 issue of the Journal of the American Medical Association.

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Clinical Features Differ for Men and Women With Heart Failure

WEDNESDAY, Aug. 24 (HealthDay News) -- Compared to men, women hospitalized for heart failure have different clinical characteristics and length of hospital stay, but similar clinical presentations, in-hospital mortality, and quality of care for most parameters, according to a study published online Aug. 23 in Circulation: Heart Failure.

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Six Factors Impact Survival in Elderly Asians With Cancer

WEDNESDAY, Aug. 24 (HealthDay News) -- Six domains of comprehensive geriatric assessment (CGA) including age, albumin level, Eastern Cooperative Oncology Group (ECOG) performance status, geriatric depression scale (GDS) status, malnutrition risk, and disease stage are important predictors of overall survival (OS) in elderly Asian patients with cancer, according to a study published online Aug. 22 in the Journal of Clinical Oncology.

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Dietary Portfolio Significantly Lowers LDL-C in Hyperlipidemia

TUESDAY, Aug. 23 (HealthDay News) -- Patients with hyperlipidemia using a specific dietary portfolio at different levels of intensity have greater reductions in low-density lipoprotein cholesterol (LDL-C) during six months of follow-up than those receiving low-saturated fat dietary advice, according to a study published Aug. 24/31 in the Journal of the American Medical Association.

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Hospitalization Ups Unintentional Discontinuation of Meds

TUESDAY, Aug. 23 (HealthDay News) -- Hospital or intensive care unit (ICU) admission is associated with unintentional discontinuation of medication for chronic diseases, according to a study published online Aug. 23 in the Journal of the American Medical Association.

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Mammography Decline Linked to Fall in Hormone Therapy

TUESDAY, Aug. 23 (HealthDay News) -- The decrease in hormone therapy (HT) use seen in the United States is correlated with a decrease in mammography rates among U.S. women aged 50 to 64 years, but not in women 65 years or older, according to a study published online Aug. 22 in Cancer.

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U.S. Door-To-Balloon Time Shortens From 2005 to 2010

TUESDAY, Aug. 23 (HealthDay News) -- The door-to-balloon (D2B) time (from hospital arrival to mechanical reperfusion) in patients with acute myocardial infarction (MI) undergoing primary percutaneous coronary intervention in the United States improved between 2005 and 2010, according to a study published online Aug. 22 in Circulation.

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Nigral Pathology Tied to Mild Parkinsonism in Elderly

FRIDAY, Aug. 19 (HealthDay News) -- Nigral neuronal loss is associated with mild parkinsonian signs, including impaired motor function in older adults without Parkinson's disease (PD), according to a study published online Aug. 11 in the Annals of Neurology.

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Excess Body Fat in Elderly Tied to Decreased Life Expectancy

FRIDAY, Aug. 19 (HealthDay News) -- Excess body fat, as measured by body mass index (BMI), in elderly adults older than 75 years is associated with decreased life expectancy, according to a study published in the June issue of the Journal of the American Geriatrics Society.

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Moderate Drinking Tied to Lower Dementia Risk in Seniors

THURSDAY, Aug. 18 (HealthDay News) -- Light to moderate drinking is associated with a decreased risk of dementia and cognitive impairment in older individuals and does not appear to be linked to impaired cognition in younger individuals, according to a review published online Aug. 11 in Neuropsychiatric Disease and Treatment.

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CDC: 2010/2011 Flu Vaccination Coverage Studied

THURSDAY, Aug. 18 (HealthDay News) -- Influenza vaccination coverage among health care personnel (HCP) and pregnant women in the 2010/2011 influenza season was similar to coverage for the 2009/2010 season, according to two reports in the Aug. 19 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Increase in U.S. Inpatient Psych Care in All but Elderly

THURSDAY, Aug. 18 (HealthDay News) -- From 1996 to 2007, inpatient discharges in short-stay facilities for a primary psychiatric diagnosis in the United States increased significantly for children, adolescents, and adults, and decreased for the elderly, according to a study published online Aug. 1 in the Archives in General Psychiatry.

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High Cumulative Malpractice Risk for All Physicians

THURSDAY, Aug. 18 (HealthDay News) -- Physicians in all specialties have a high cumulative risk of facing a malpractice claim by age 65; although most claims do not lead to indemnity payments, according to a study published in the Aug. 18 issue of the New England Journal of Medicine.

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Significant Differences ID'd Between Antimanic Drugs

WEDNESDAY, Aug. 17 (HealthDay News) -- The various treatments for acute mania show statistically and clinically significant differences with haloperidol, risperidone, and olanzapine having better efficacy than other drugs, and olanzapine, risperidone, and quetiapine having lower dropout rates than haloperidol, which has the highest efficacy, according to a meta-analysis published online Aug. 17 in The Lancet.

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Niacin Linked to Improved Erectile Function

FRIDAY, Aug. 12 (HealthDay News) -- Men with moderate to severe erectile dysfunction (ED) and dyslipidemia have significantly improved erectile function with treatment with niacin, according to a study published online Aug. 2 in The Journal of Sexual Medicine.

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Depression Tied to Moderately Higher Stroke Risk in Women

FRIDAY, Aug. 12 (HealthDay News) -- Women with depression have a moderate but significant increased risk of subsequent stroke, according to a study published online Aug. 11 in Stroke.

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Cognitive Function Tied to Markers of Cognitive Reserve

THURSDAY, Aug. 11 (HealthDay News) -- Cognitive performance is correlated with markers of reserve; but the rate of cognitive decline is similar in all reserve groups, with a difference in cognitive decline seen only in the high occupation group, according to a study published in the August issue of the Annals of Neurology.

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Typical Alzheimer Patterns Less Salient in Very-Old

THURSDAY, Aug. 11 (HealthDay News) -- Certain cognitive and morphometric brain abnormalities associated with Alzheimer's disease (AD) are less salient in very-old patients than in young-old patients, according to a study published online Aug. 10 in Neurology.

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Race, Gender Discrepancies in Neurologist Care for Parkinson's

WEDNESDAY, Aug. 10 (HealthDay News) -- Women and nonwhite patients with Parkinson's disease (PD) are less likely to receive neurologist care than white men, and patients receiving neurologist care may have improved selected clinical outcomes and a lower likelihood of death, according to a study published online Aug. 10 in Neurology.

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Higher Diagnostic Blood Loss Tied to Higher Anemia Risk

WEDNESDAY, Aug. 10 (HealthDay News) -- Increased blood loss from diagnostic phlebotomy increases the risk for moderate to severe hospital-acquired anemia (HAA) among patients with acute myocardial infarction (AMI), according to a study published online Aug. 8 in the Archives of Internal Medicine.

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Model to Assess AMD Risk Successfully Designed, Validated

WEDNESDAY, Aug. 10 (HealthDay News) -- A risk assessment model, comprised of demographic, environmental, phenotypic, and genetic risk factors, designed for predicting the development of advanced age-related macular degeneration (AMD), has been validated with good discrimination, and excellent calibration and overall performance, according to a study published online Aug. 8 in the Archives of Ophthalmology.

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Poor Verbal Memory in Elderly With Low Ejection Fraction

WEDNESDAY, Aug. 10 (HealthDay News) -- In older patients with heart failure, there is a significant association between memory function and left ventricular ejection fraction (EF), with verbal delayed recall and recognition most affected by an EF of less than 30 percent, according to a study published in the August issue of the Archives of Neurology.

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Lower Mortality for Older Blacks Receiving Dialysis

TUESDAY, Aug. 9 (HealthDay News) -- Blacks older than 50 years who are undergoing dialysis have lower mortality compared to whites, as opposed to younger blacks who have an increased risk of death, according to a study published in the Aug. 10 issue of the Journal of the American Medical Association.

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Sleep-Disordered Breathing Tied to Dementia in Older Women

TUESDAY, Aug. 9 (HealthDay News) -- Older women with sleep-disordered breathing have an increased risk of cognitive impairment and dementia, according to a study published in the Aug. 10 issue of the Journal of the American Medical Association.

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Doublet Chemo Improves Survival in Elderly With NSCLC

TUESDAY, Aug. 9 (HealthDay News) -- Despite more toxic effects, doublet chemotherapy with carboplatin and weekly paclitaxel is associated with significantly higher survival benefits than monotheraphy with either vinorelbine or gemcitabine in elderly patients with advanced non-small-cell lung cancer (NSCLC), according to a study published online Aug. 9 in The Lancet.

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Leaky Calcium Channels Tied to Aging Muscle Function Loss

TUESDAY, Aug. 9 (HealthDay News) -- The ryanodine receptor 1 (RyR1) channel complex is oxidized, nitrosylated, and depleted of calstabin1 with age, resulting in "leaky" calcium channels, which appear to contribute to the age-related loss of muscle function, according to an experimental study published in the Aug. 3 issue of Cell Metabolism.

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Soy Isoflavones Don't Prevent Menopausal Bone Loss

TUESDAY, Aug. 9 (HealthDay News) -- Soy isoflavone tablets, administered once daily, do not prevent bone loss or menopausal symptoms in women during the first five years of menopause, according to a study published in the Aug. 8/22 issue of the Archives of Internal Medicine.

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AHRQ: CPAP Highly Effective in Treating Obstructive Sleep Apnea

MONDAY, Aug. 8 (HealthDay News) -- Continuous positive airway pressure (CPAP) machines and mandibular advancement devices (MADs) are very effective in treating obstructive sleep apnea (OSA), but evidence supporting weight loss or surgery is not as strong, according to a report published Aug. 8 by the Agency for Healthcare Research and Quality (AHRQ).

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Physical Activity Ups Satisfaction With Body Image, Function

MONDAY, Aug. 8 (HealthDay News) -- Predictors of improvement in satisfaction with body function and appearance in mid-life and older adults include greater physical activity, greater reductions in body mass index (BMI) and depressive symptoms, and being white, according to a study published in the June issue of the Annals of Behavioral Medicine.

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More Neurology Residents Comfortable Using tPA for Stroke

MONDAY, Aug. 8 (HealthDay News) -- The number of graduating U.S. neurology residents with experience, and who report feeling comfortable, treating acute ischemic stroke patients with tissue-type plasminogen activator (tPA) increased from 2000 to 2010, with more residents having exposure to stroke teams and formal training in the National Institutes of Health Stroke Scale, according to a study published online Aug. 4 in Stroke.

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Cost of Interacting With Payers Higher in U.S. Than Canada

FRIDAY, Aug. 5 (HealthDay News) -- Physician practices in the United States spend considerably more on interactions with health plans than Canadian practices, according to a study published in the August issue of Health Affairs.

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Specific, Reliable Biomarkers ID'd for Alzheimer's Disease

FRIDAY, Aug. 5 (HealthDay News) -- Specific serum autoantibodies can serve as biomarkers to diagnose Alzheimer's disease (AD) throughout the course of the disease with high sensitivity and specificity, according to a study published online Aug. 3 in PLoS ONE.

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Antidepressant Prescriptions for Non-Psych Disorders Up

FRIDAY, Aug. 5 (HealthDay News) --The number of antidepressants prescribed by non-psychiatrist physicians to patients without a psychiatric disorder continues to rise, according to a study published in the August issue of Health Affairs.

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Nurse Case Managers Improve Cardiac Risk Control in Diabetes

FRIDAY, Aug. 5 (HealthDay News) -- Nurse case managers can improve the percentage of patients with diabetes who achieve control of hypertension, hyperglycemia, and hyperlipidemia, according to a study published in the August issue of Diabetes Care.

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Longevity Has No Link to a Distinct Lifestyle

THURSDAY, Aug. 4 (HealthDay News) -- Individuals with exceptional longevity are not distinct from the general population in terms of lifestyle factors, including body mass index, smoking, physical activity, or low-calorie diet, according to a study published online Aug. 3 in the Journal of the American Geriatrics Society.

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Lower Post MI Physical Activity in Areas With Low Income

THURSDAY, Aug. 4 (HealthDay News) -- Low neighborhood socioeconomic status (SES) is a significant predictor of lower uptake of leisure-time physical activity (LTPA) by survivors of myocardial infarction (MI), even after adjusting for individual SES and clinical profile, according to a study published online Aug. 2 in the American Journal of Preventive Medicine.

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High Risk of Adverse Outcomes Tied to SSRI Use in Elderly

WEDNESDAY, Aug. 3 (HealthDay News) -- In older individuals with depression, use of selective serotonin reuptake inhibitors (SSRIs) and certain other antidepressants is associated with higher risk of adverse outcomes than tricyclic antidepressants (TCAs), according to a study published online Aug. 2 in BMJ.

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Oseltamivir-Resistant Pandemic H1N1 2009 Virus Emerging

WEDNESDAY, Aug. 3 (HealthDay News) -- Clinicians should be aware of an emergence of oseltamivir-resistant pandemic H1N1 2009 virus, particularly in immunocompromised patients, according to a study published online July 29 in the U.S. Centers for Disease Control and Prevention's Emerging Infectious Diseases.

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Risperidone Not Effective for Military-Related PTSD

TUESDAY, Aug. 2 (HealthDay News) -- The second-generation antipsychotic risperidone is not an effective treatment for veterans with chronic military-related posttraumatic stress disorder (PTSD) not responding to serotonin reuptake-inhibitors (SRIs) treatment, according to a study published in the Aug. 3 violence/human rights-themed issue of the Journal of the American Medical Association.

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Even Small Amount of Exercise Lowers Heart Disease Risk

TUESDAY, Aug. 2 (HealthDay News) -- A dose-response relationship is seen between leisure-time physical activity (LTPA) and the risk of coronary heart disease (CHD) risk, with significant reductions seen with less than or equivalent to 150 minutes/week of moderate-intensity LTPA and additional risk reductions for those engaging in activity equivalent to 300 minutes/week, according to a meta-analysis published online Aug. 1 in Circulation.

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New Guidelines Issued for COPD Diagnosis, Management

TUESDAY, Aug. 2 (HealthDay News) -- Clinicians should use spirometry for screening or diagnosis, and inhaled therapies, pulmonary rehabilitation programs, and supplemental oxygen therapy to improve management of chronic obstructive pulmonary disorder (COPD), according to the joint practice guidelines of the American College of Physicians (ACP), the American College of Chest Physicians, the American Thoracic Society, and the European Respiratory Society, published in the Aug. 2 issue of the Annals of Internal Medicine.

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Midlife Vascular Risk Factors Impact Structural Brain Aging

MONDAY, Aug. 1 (HealthDay News) -- Hypertension, diabetes, smoking, and obesity in midlife are associated with accelerated progression of structural brain aging, and decline in executive function a decade later, according to a study published in the Aug. 2 issue of Neurology.

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Knee Arthroplasty Unaffected by Patellar Resurfacing

MONDAY, Aug. 1 (HealthDay News) -- Neither patellar resurfacing nor the design of the prosthetic affects the clinical outcome of total knee arthroplasty, according to a study published in the July 20 issue of The Journal of Bone & Joint Surgery.

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