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Category: Endocrinology | Monthly Briefing

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September 2011 Briefing - Diabetes & Endocrinology

Last Updated: October 03, 2011.

 

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Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for September 2011. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Doctors, Patients Identify Tacit Clues in Their Interactions

FRIDAY, Sept. 30 (HealthDay News) -- Both doctors and patients identify tacit clues as well as judgments based on these clues during video elicitation interviews of health maintenance examinations, according to a study published in the October issue of the Journal of Evaluation in Clinical Practice.

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Physical Activity Tied to Excess Eating Via Executive Function

FRIDAY, Sept. 30 (HealthDay News) -- Physical activity indirectly modifies eating behavior and may suppress overeating by strengthening executive function, according to a review published in the October issue of Obesity Reviews.

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Three New Gene Loci ID'd for Type 1 Diabetes Susceptibility

FRIDAY, Sept. 30 (HealthDay News) -- Three new single nucleotide polymorphisms (SNPs) have been identified, which are significantly associated with type 1 diabetes (T1D) susceptibility, according to a study published online Sept. 29 in PLoS Genetics.

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Tamoxifen Use Tied to Diabetes Risk in Breast Cancer Survivors

FRIDAY, Sept. 30 (HealthDay News) -- Current tamoxifen therapy is associated with a significantly increased incidence of diabetes in older breast cancer survivors, according to a study published online Sept. 20 in Cancer.

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Food Patterns Tied to Systemic and Vascular Inflammation

THURSDAY, Sept. 29 (HealthDay News) -- Diets rich in high-fiber, low-fat, and low-sugar foods are favorably associated with markers of inflammation, whereas milk fat and sweets and cakes patterns are associated with adverse effects, according to a study published in the October issue of the Journal of Internal Medicine.

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More Frequent Doctor Visits Improve Diabetes Control

THURSDAY, Sept. 29 (HealthDay News) -- More frequent encounters between patients with diabetes mellitus (DM) and physicians decrease the time needed to control elevated hemoglobin A1c (HbA1c), blood pressure (BP), and low-density lipoprotein cholesterol (LDL-C), according to a study published in the Sept. 26 issue of the Archives of Internal Medicine.

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Rapeseed Oil Rapidly Improves Hyperlipidemia

THURSDAY, Sept. 29 (HealthDay News) -- For hyperlipidemic individuals, replacing a diet rich in saturated dairy fat (DF) with a rapeseed oil (RO)-based diet for three weeks improves the serum lipoprotein profile, with reductions in triglyceride levels, according to a study published in the October issue of the Journal of Internal Medicine.

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AHA: Tools, Challenges for Assessing Adiposity Identified

WEDNESDAY, Sept. 28 (HealthDay News) -- Body mass index (BMI) and waist circumference (WC) should be used as primary tools for assessing adiposity, according to an American Heart Association scientific statement published online Sept. 26 in Circulation.

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Cognition Similar for Standard, Intensive Glycemic Control

WEDNESDAY, Sept. 28 (HealthDay News) -- Intensive glycemic lowering is not better than standard glycemic control for preventing cognitive decline in patients with type 2 diabetes, despite a higher total brain volume, according to a study published online Sept. 28 in The Lancet Neurology.

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U.S. Docs Feel They Give More Patient Care Than Required

TUESDAY, Sept. 27 (HealthDay News) -- Many primary care physicians in the United States believe that their patients are receiving too much medical care, and that the pressure to do more than is necessary could be reduced by malpractice reform, adjusting financial incentives, and spending more time with patients, according to a study published in the Sept. 26 issue of the Archives of Internal Medicine.

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Reasons for Referral to Specific Docs Differ Among Physicians

TUESDAY, Sept. 27 (HealthDay News) -- Primary care physicians (PCPs) and medical and surgical specialists differ in their reasons for selecting specific colleagues for referrals, with PCPs more concerned about physician communication and medical record sharing than specialists, according to a study published online Sept. 16 in the Journal of General Internal Medicine.

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Asthma Prevalence Elevated in Youth With Diabetes

TUESDAY, Sept. 27 (HealthDay News) -- Asthma is more prevalent in youth with diabetes compared to the general U.S. population, and is associated with poor glycemic control in youth with type 1 diabetes, especially if untreated, according to a study published online Sept. 26 in Pediatrics.

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Diabetes-Free Life Expectancy at 18 Years Down Since 1980s

MONDAY, Sept. 26 (HealthDay News) -- The diabetes-free life expectancy at 18 years of age in the United States decreased in both men and women between the 1980s and 2000s, with obese individuals experiencing the greatest losses, according to a study published in the October issue of Diabetes Care.

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Glycemic Control Risk Factors ID'd in Youth With Diabetes

FRIDAY, Sept. 23 (HealthDay News) -- Duration of diabetes, socioeconomic status, extensive daily media viewing, but not physical activity are significant risk factors of poor glycemic control in children, adolescents, and young adults with type 1 diabetes, according to a study published online Sept. 16 in Diabetes Care.

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Many Cushing Syndrome-EAS Tumors Found in Chest Cavity

FRIDAY, Sept. 23 (HealthDay News) -- For patients with Cushing syndrome (CS) secondary to ectopic adrenocorticotropic hormone (ACTH) secretion (EAS) who attend a comprehensive cancer center, nearly 50 percent have tumors in the chest cavity, notably bronchial carcinoid and small-cell lung cancer, according to a study published in the Oct. 1 issue of Cancer.

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Total Sleep Time Tied to Obese Teen Glucose Homeostasis

FRIDAY, Sept. 23 (HealthDay News) -- Inadequate or excessive sleep is associated with disruptions in insulin secretion and glucose homeostasis in obese adolescents, according to a study published online Sept. 20 in Diabetes Care.

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Glucagon-Like Peptide-1 Therapy Ups Pancreatitis Risk

FRIDAY, Sept. 23 (HealthDay News) -- The use of exenatide and sitagliptin for type 2 diabetes is associated with a higher odds ratio of pancreatitis and increased reports of pancreatic cancer, according to a study published in the July issue of Gastroenterology.

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SNP in SUV39H2 Tied to Complications in Diabetes

THURSDAY, Sept. 22 (HealthDay News) -- The minor T-allele of exonic single nucleotide polymorphism (SNP) rs17353856 in SUV39H2 is associated with retinopathy in patients with type 1 diabetes, and shows a trend toward an association with diabetic nephropathy and cardiovascular disease, according to a study published online Sept. 6 in Diabetes.

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Nocturnal Hypertension Ups cIMT in Youth With Diabetes

THURSDAY, Sept. 22 (HealthDay News) -- Nocturnal hypertension in children and adolescents with type 1 diabetes is associated with increased carotid intima-media thickness (cIMT), according to a study published online Sept. 12 in Diabetes Care.

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Circulating Glucose Levels Impact Responses to Food Cues

THURSDAY, Sept. 22 (HealthDay News) -- Mild hypoglycemia activates limbic-striatal brain regions in response to food cues resulting in a increased desire for high-calorie food, whereas higher circulating glucose levels predict increased medial prefrontal cortex activation, a response which is absent in obese individuals, according to a study published online Sept. 19 in the Journal of Clinical Investigation.

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Mortality Up in Hospitals With More Minority Trauma Patients

WEDNESDAY, Sept. 21 (HealthDay News) -- The odds of in-hospital mortality for trauma patients are associated with the proportion of minority patients in the hospital, according to a study published online Sept. 19 in the Archives of Surgery.

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Methylphenidate Hydrochloride Delays Puberty in Monkeys

WEDNESDAY, Sept. 21 (HealthDay News) -- Methylphenidate hydrochloride (MPH) delays pubertal progression with impaired testicular descent, reduced testicular volume, and decreased serum testosterone levels in juvenile male rhesus monkeys, according to an experimental study published online Sept. 19 in the Proceedings of the National Academy of Sciences.

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Chronic Total Occlusion PCI Improves Outcomes in Diabetes

TUESDAY, Sept. 20 (HealthDay News) -- Percutaneous coronary intervention (PCI) of chronic total occlusions (CTOs) is associated with reduced mortality and reduced need for coronary artery bypass grafting in patients with diabetes mellitus (DM), according to a study published in the Oct. 1 issue of The American Journal of Cardiology.

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Bisphenol A Exposure Not Linked to Type 2 Diabetes

TUESDAY, Sept. 20 (HealthDay News) -- Urinary bisphenol A (BPA) levels are not associated with self-reported type 2 diabetes, according to a study published in the Sept. 20 issue of the Annals of Internal Medicine.

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Diabetes Ups Risk of All-Cause Dementia, Alzheimer's Disease

TUESDAY, Sept. 20 (HealthDay News) -- Patients with diabetes have an increased risk of developing all-cause dementia, Alzheimer's disease (AD), and vascular dementia (VaD) than those with normal glucose tolerance, with elevated two-hour postload glucose (PG) but not fasting plasma glucose (FPG) levels associated with the increased risk, according to a study published in the Sept. 20 issue of Neurology.

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Similar Lipid-Triglyceride Storage in Obese, Lean Women

MONDAY, Sept. 19 (HealthDay News) -- Both upper-body obese (UBO) and lean women exhibit similar storage of very low density lipids-triglyceride (VLDL-TG) in visceral, upper-body subcutaneous (UBSQ), and lower-body subcutaneous (LBSQ) fat, with no significant differences in the trafficking pattern into these adipose tissue depots, according to a study published online Sept. 12 in Diabetes.

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Work Intensity Similar Across Physician Specialties

MONDAY, Sept. 19 (HealthDay News) -- The level of physician work intensity appears to be similar among specialties, with variations in the specific dimensions of stress, physical demands, performance, and temporal demand, according to a study published online Sept. 3 in Medical Care.

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White Coat Adherence Seen in Children With Type 1 Diabetes

THURSDAY, Sept. 15 (HealthDay News) -- For children with type 1 diabetes, those with low levels of hemoglobin A1c (A1C) may be more likely to increase the frequency of blood glucose monitoring (BGM) prior to a scheduled visit to the clinic, according to a study published online Aug. 18 in Diabetes Care.

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Pregnancy Outcomes Similar With Glycemic Index, Fiber Diets

FRIDAY, Sept. 16 (HealthDay News) -- Following a low-glycemic index (LGI) diet or a conventional high-fiber moderate GI (HF) diet produces comparable pregnancy outcomes for women with gestational diabetes mellitus (GDM), according to a study published online Sept. 6 in Diabetes Care.

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White Fruits, Vegetables Tied to Lower Incident Stroke Risk

FRIDAY, Sept. 16 (HealthDay News) -- Higher consumption of white fruits and vegetables is associated with a lower risk of incident stroke, according to a study published online Sept. 15 in Stroke.

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Prehypertension-Hypertension Conversion Rate Tied to Race

WEDNESDAY, Sept. 14 (HealthDay News) -- Conversion from prehypertension to hypertension is more accelerated in blacks than in whites, according to a study published online Sept. 12 in Hypertension.

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Erectile Dysfunction Ups Risk of Cardiovascular Disease

WEDNESDAY, Sept. 14 (HealthDay News) -- Erectile dysfunction (ED) significantly increases the risk of cardiovascular disease (CVD), coronary heart disease, stroke, and all-cause mortality, according to a meta-analysis published in the Sept. 20 issue of the Journal of the American College of Cardiology.

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Many Mistakenly Believe FDA OKs Only Safe, Effective Drugs

WEDNESDAY, Sept. 14 (HealthDay News) -- A considerable proportion of the U.S. public mistakenly believes that the U.S. Food and Drug Administration approves only effective and safe drugs, but providing consumer explanations can lead to better drug choices, according to a study published in the Sept. 12 issue of the Archives of Internal Medicine.

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Computer Nutrition Program Doesn't Affect Blood Lipids

TUESDAY, Sept. 13 (HealthDay News) -- Use of a computer-tailored nutrition education intervention does not affect blood lipid levels any differently than generic nutrition information, according to a study published in the September issue of the Journal of Nutrition Education and Behavior.

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Fatherhood Decreases Waking, Evening Testosterone Levels

TUESDAY, Sept. 13 (HealthDay News) -- Baseline waking testosterone levels are high in men who are likely to become partnered fathers, and both waking and evening testosterone levels decline significantly after men become fathers, according to a study published online Sept. 12 in the Proceedings of the National Academy of Sciences.

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Metabolic Syndrome Beats Obesity for Heart Failure Risk

TUESDAY, Sept. 13 (HealthDay News) -- Obese individuals who are metabolically healthy have a lower risk of heart failure than those with metabolic syndrome (MetS) who are normal weight, according to a study published in the Sept. 20 issue of the Journal of the American College of Cardiology.

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Hospitalizations for Eating Disorders Up Over Last Decade

MONDAY, Sept. 12 (HealthDay News) -- Although hospitalizations with a principal or secondary eating-disorder diagnosis increased by 24 percent from 1999-2000 to 2008-2009, there has been a decrease in hospitalizations with a principal diagnosis of eating disorder from 2007-2008 to 2008-2009, according to a statistical brief based on data from the Healthcare Cost and Utilization Project (HCUP) published online Sept. 8 by the Agency for Healthcare Research and Quality (AHRQ).

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Gestational Diabetes + Obesity Upregulates Endothelial Lipase

MONDAY, Sept. 12 (HealthDay News) -- Pregnancies complicated by obesity and gestational diabetes mellitus (GDM) show upregulated endothelial lipase (EL) expression, according to a study published online Aug. 18 in Diabetes.

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Matrix Protein Production in Diabetes Complications Studied

MONDAY, Sept. 12 (HealthDay News) -- Glucose-induced extracellular matrix protein fibronectin (FN) upregulation in endothelial cells and in the retina of diabetic rats is mediated through microR-146a (miR-146a), according to an experimental study published online Sept. 1 in Diabetes.

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Survival Up for Early-Onset Type 1 Diabetes Since 1980s

FRIDAY, Sept. 9 (HealthDay News) -- For patients with early-onset type 1 diabetes survival has increased over time, but survival for individuals with late-onset type 1 diabetes has decreased since the 1980s, according to a study published online Sept. 8 in BMJ.

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Commercial Program Offers More Weight Loss Than Standard Care

THURSDAY, Sept. 8 (HealthDay News) -- Obese or overweight participants in a commercial weight loss program lose twice as much weight over a 12 month period than those in standard treatment, according to a study published online Sept. 8 in The Lancet.

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Comparative Efficacy Proposed for European Drug Approval

WEDNESDAY, Sept. 7 (HealthDay News) -- New drugs should be compared with existing treatments instead of placebo before their approval in Europe, according to a report published online Sept. 6 in the BMJ.

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BMI of 25 or More Ups Mortality Among Black Women

WEDNESDAY, Sept. 7 (HealthDay News) -- For black women, the risk of death from any cause increases with an increasing body mass index (BMI) of 25.0 kg/m² or higher, and having a large waist circumference is associated with an increased risk of death among non-obese women, according to a study published in the Sept. 8 issue of the New England Journal of Medicine.

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Medical Students Show Racial, Cultural Patient Preference

WEDNESDAY, Sept. 7 (HealthDay News) -- Medical students may have a preferential bias toward whites and wealthier patients, but this does not appear to influence their clinical decision making or physician-patient interactions, according to a study published in the Sept. 7 medical education-themed issue of the Journal of the American Medical Association.

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Odds of Board Certification Vary in New Doctors

WEDNESDAY, Sept. 7 (HealthDay News) -- Certification of recent U.S. medical school graduates by the American Board of Medical Specialties (ABMS) varies across specialties by educational and demographic factors, according to a study published in the Sept. 7 medical education-themed issue of the Journal of the American Medical Association.

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Combined Lifestyle Factors Cut Risk of Diabetes

WEDNESDAY, Sept. 7 (HealthDay News) -- A combination of lifestyle factors is associated with lower risk of new-onset diabetes in older adults, according to a study published in the Sept. 6 issue of the Annals of Internal Medicine.

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Many Hospital Staff Uniforms Contaminated With Bacteria

WEDNESDAY, Sept. 7 (HealthDay News) -- More than 60 percent of hospital staff uniforms are contaminated with potentially pathogenic bacteria, including drug-resistant species, according to a study published in the September issue of the American Journal of Infection Control.

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More Weight Loss for Duodenal Switch Than Gastric Bypass

TUESDAY, Sept. 6 (HealthDay News) -- Duodenal switch results in greater reduction in body mass index (BMI) and total and low-density lipoprotein (LDL) cholesterol than gastric bypass, but has a higher rate of adverse events than gastric bypass, according to a study published in the Sept. 6 issue of the Annals of Internal Medicine.

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High Adiposity Tied to Fewer Hot Flashes in Older Women

FRIDAY, Sept. 2 (HealthDay News) -- Having a higher body mass index (BMI) and waist circumference is associated with fewer physiologically measured hot flashes in older postmenopausal women with hot flashes, according to a study published online July 21 in the Journal of Clinical Endocrinology & Metabolism.

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About Half of U.S. Population Consume Sugary Beverages Daily

THURSDAY, Sept. 1 (HealthDay News) -- Approximately one-half of the U.S. population consumes sugar drinks on a given day with consumption varying with age, gender, racial group, and family income, according to a report published online Aug. 31 by the Center for Disease Control and Prevention's National Center for Health Statistics (NCHS).

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