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Category: Gynecology | Monthly Briefing

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September 2011 Briefing - OBGYN & Women’s Health

Last Updated: October 03, 2011.

 

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Here are what the editors at HealthDay consider to be the most important developments in OBGYN & Women's Health for September 2011. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Doctors, Patients Identify Tacit Clues in Their Interactions

FRIDAY, Sept. 30 (HealthDay News) -- Both doctors and patients identify tacit clues as well as judgments based on these clues during video elicitation interviews of health maintenance examinations, according to a study published in the October issue of the Journal of Evaluation in Clinical Practice.

Abstract
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Tamoxifen Use Tied to Diabetes Risk in Breast Cancer Survivors

FRIDAY, Sept. 30 (HealthDay News) -- Current tamoxifen therapy is associated with a significantly increased incidence of diabetes in older breast cancer survivors, according to a study published online Sept. 20 in Cancer.

Abstract
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Hip Fracture Increases Short-Term Mortality in Older Women

THURSDAY, Sept. 29 (HealthDay News) -- There is an increased risk of mortality within the year after hip fracture in women aged 65 to 79 years, and in those older than 80 years who are in exceptionally good health, according to a study published online Sept. 26 in the Archives of Internal Medicine.

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Fear of Childbirth Tied to Higher Odds of Cesarean Section

WEDNESDAY, Sept. 28 (HealthDay News) -- Emergency and elective cesarean sections (CS) are more common in women with a fear of childbirth, even after psychological counseling, according to a study published online July 24 in Acta Obstetricia et Gynecologica Scandinavica.

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Alternate Chromosome 17 Genes Detect True HER2 Status

WEDNESDAY, Sept. 28 (HealthDay News) -- For patients with breast cancer and polysomy 17, the true gene status of human epidermal growth factor receptor 2 (HER2) can be effectively determined by use of additional chromosome 17 fluorescent in situ hybridization (FISH) studies for Smith-Magenis syndrome (SMS), retinoic acid receptor alpha (RARA), and tumor protein p53 (TP53) genes, rather than the HER2-to-centromeric probe (CEP17) ratio, according to a study published online Sept. 26 in the Journal of Clinical Oncology.

Abstract
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Quadrivalent HPV Vaccine More Cost-Effective Than Bivalent

WEDNESDAY, Sept. 28 (HealthDay News) -- Due to different efficacy and protection offered by the bivalent and quadrivalent human papillomavirus (HPV) vaccines, the bivalent vaccine would need to be cheaper than the quadrivalent in order to be equally cost-effective, according to a study published online Sept. 27 in BMJ.

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U.S. Docs Feel They Give More Patient Care Than Required

TUESDAY, Sept. 27 (HealthDay News) -- Many primary care physicians in the United States believe that their patients are receiving too much medical care, and that the pressure to do more than is necessary could be reduced by malpractice reform, adjusting financial incentives, and spending more time with patients, according to a study published in the Sept. 26 issue of the Archives of Internal Medicine.

Abstract
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Caffeinated Coffee Reduces Women's Depression Risk

TUESDAY, Sept. 27 (HealthDay News) -- The risk of depression in U.S. women decreases in a dose-dependent manner with increasing consumption of caffeinated coffee, according to a study published in the Sept. 26 issue of the Archives of Internal Medicine.

Abstract
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ESR1 Expression Predicts Tamoxifen Benefit in Breast CA

TUESDAY, Sept. 27 (HealthDay News) -- Expression of ESR1 predicts tamoxifen benefit in estrogen receptor (ER)-positive breast cancer, with low levels of expression indicative of tamoxifen resistance, according to a study published online Sept. 26 in the Journal of Clinical Oncology.

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Reasons for Referral to Specific Docs Differ Among Physicians

TUESDAY, Sept. 27 (HealthDay News) -- Primary care physicians (PCPs) and medical and surgical specialists differ in their reasons for selecting specific colleagues for referrals, with PCPs more concerned about physician communication and medical record sharing than specialists, according to a study published online Sept. 16 in the Journal of General Internal Medicine.

Abstract
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Updated Guides Compare Treatments for GERD

MONDAY, Sept. 26 (HealthDay News) -- Updated, evidence-based, reader-friendly reports comparing treatments for gastroesophageal reflux disease (GERD) have been released by the Agency for Healthcare Research and Quality (AHRQ) to help guide patient and physician decision-making in treating this condition that affects up to 4 percent of Americans.

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Adjuvant Zoledronic Acid Not Beneficial in Breast Cancer

MONDAY, Sept. 26 (HealthDay News) -- For patients with early-stage breast cancer, the addition of zoledronic acid to standard adjuvant therapy does not offer any benefit for disease-free or overall survival, according to a study published in the New England Journal of Medicine to coincide with presentation at the 2011 European Multidisciplinary Cancer Congress, held from Sept. 23 to 27 in Stockholm, Sweden.

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Lower Walking Speed, Altered Gait in Overweight Women

MONDAY, Sept. 26 (HealthDay News) -- Overweight, older women have altered gait and reduced walking performance due to poor relative strength and rate of torque development (RTD) of lower-extremity muscles compared to older women of normal weight, according to a study published in the October issue of the Journal of Electromyography and Kinesiology.

Abstract
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Fewer U.S. Hospitals Provide Free Infant Formula

MONDAY, Sept. 26 (HealthDay News) -- The proportion of U.S. hospitals that distribute industry-sponsored formula sample packs decreased from 2007 to 2010, with the biggest drop in states with a higher proportion of sample-pack-free hospitals in 2007, according to a study published online Sept. 26 in Pediatrics.

Abstract
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Previous Infant Death Ups Subsequent Stillbirth Risk

THURSDAY, Sept. 22 (HealthDay News) -- Women whose first pregnancy resulted in infant death are nearly three times more likely to have a stillbirth in a subsequent pregnancy, with black women having a higher risk than white women, according to a study published online Sept. 21 in the BJOG: An International Journal of Obstetrics and Gynaecology.

Abstract
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Mortality Up in Hospitals With More Minority Trauma Patients

WEDNESDAY, Sept. 21 (HealthDay News) -- The odds of in-hospital mortality for trauma patients are associated with the proportion of minority patients in the hospital, according to a study published online Sept. 19 in the Archives of Surgery.

Abstract
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Preterm Birth Ups Mortality Risk in Young Adulthood

WEDNESDAY, Sept. 21 (HealthDay News) -- Low gestational age at birth is associated with increased mortality in young adulthood, according to a study published in the Sept. 21 issue of the Journal of the American Medical Association.

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Progressive Decline in Child, Maternal Mortality Since 1990

TUESDAY, Sept. 20 (HealthDay News) -- Although many countries are progressing in reducing maternal and child mortality, only a small number of developing countries will achieve Millennium Development Goals (MDGs) 4 or 5 by 2015, according to a study published online Sept. 20 in The Lancet.

Abstract
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Similar Lipid-Triglyceride Storage in Obese, Lean Women

MONDAY, Sept. 19 (HealthDay News) -- Both upper-body obese (UBO) and lean women exhibit similar storage of very low density lipids-triglyceride (VLDL-TG) in visceral, upper-body subcutaneous (UBSQ), and lower-body subcutaneous (LBSQ) fat, with no significant differences in the trafficking pattern into these adipose tissue depots, according to a study published online Sept. 12 in Diabetes.

Abstract
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No Long-Term Cognitive Effect of Fatty Acids Found in Infants

MONDAY, Sept. 19 (HealthDay News) -- Long-chain polyunsaturated fatty acid (LCPUFA) supplementation has no effect on children's cognition after age 9; however, a high percentage of breastfeeding and exposure to higher levels of LCPUFA during the first 14 months is positively associated with child mental development, according to two studies published online Sept. 19 in Pediatrics.

Abstract - Isaacs
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Abstract - Guxens
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Work Intensity Similar Across Physician Specialties

MONDAY, Sept. 19 (HealthDay News) -- The level of physician work intensity appears to be similar among specialties, with variations in the specific dimensions of stress, physical demands, performance, and temporal demand, according to a study published online Sept. 3 in Medical Care.

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Female Genital Stimulation Acts on Distinct Sensory Areas

MONDAY, Sept. 19 (HealthDay News) -- Clitoral, vaginal, cervical, and nipple self-stimulation activates specific, distinct sensory cortical regions, according to a study published online July 28 in The Journal of Sexual Medicine.

Abstract
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Pregnancy Outcomes Similar With Glycemic Index, Fiber Diets

FRIDAY, Sept. 16 (HealthDay News) -- Following a low-glycemic index (LGI) diet or a conventional high-fiber moderate GI (HF) diet produces comparable pregnancy outcomes for women with gestational diabetes mellitus (GDM), according to a study published online Sept. 6 in Diabetes Care.

Abstract
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Hospital Births More Than Halve Neonatal Deaths in China

FRIDAY, Sept. 16 (HealthDay News) -- The implementation of a large-scale, facility-based strategy of intrapartum care and hospital births significantly reduced neonatal mortality in China between 1996 and 2008, according to a study published online Sept. 16 in The Lancet.

Abstract
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Global Rates of Breast, Cervical Cancer Up Over Last 20 Years

THURSDAY, Sept. 15 (HealthDay News) -- The global incidence of breast and cervical cancer increased from 1980 to 2010, with breast cancer mortality rates increasing and cervical cancer mortality rates decreasing during the same period, according to a study published online Sept. 15 in The Lancet.

Abstract
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Women Older Than 50 Years Aware of Sexual Health Risks

THURSDAY, Sept. 15 (HealthDay News) -- Sexually active women over the age of 50 years are aware of the risk of sexually transmitted diseases (STDs), but are hesitant to consult their physicians for health information, according to a study published online Sept. 14 in the Journal of Consumer Affairs.

Abstract
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Tissue Factor Pathway Inhibitor Levels Up in Women With MI

THURSDAY, Sept. 15 (HealthDay News) -- Young women with myocardial infarction (MI) have higher tissue factor pathway inhibitor (TFPI) levels in comparison to those without MI, with increased TFPI activities and activated protein C (APC)-sensitivity correlating with MI, according to a study published online Sept. 5 in the Journal of Thrombosis and Haemostasis.

Abstract
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Mammography Screening Ups Breast Cancer Surgery Rates

WEDNESDAY, Sept. 14 (HealthDay News) -- The annual rate of breast surgery increased significantly from 1993-1995 to 2005-2008 for women in Norway aged 50 to 69 years who were invited to undergo mammography screening, according to a study published online Sept. 13 in BMJ.

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Many Mistakenly Believe FDA OKs Only Safe, Effective Drugs

WEDNESDAY, Sept. 14 (HealthDay News) -- A considerable proportion of the U.S. public mistakenly believes that the U.S. Food and Drug Administration approves only effective and safe drugs, but providing consumer explanations can lead to better drug choices, according to a study published in the Sept. 12 issue of the Archives of Internal Medicine.

Abstract
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Depression Nondisclosure to Primary Care Doctor Common

TUESDAY, Sept. 13 (HealthDay News) -- Many adults do not disclose depression to their primary care physicians because of their beliefs, with concern about the physician recommending antidepressants being the most frequent reason for nondisclosure, according to a study published in the September/October issue of the Annals of Family Medicine.

Abstract
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Venlafaxine, Clonidine Reduce Hot Flashes in Breast Cancer

TUESDAY, Sept. 13 (HealthDay News) -- Venlafaxine and clonidine effectively manage hot flashes in patients with breast cancer, with hot flash scores reducing more immediately with venlafaxine than clonidine, and reducing more significantly with clonidine during week 12 of treatment than with venlafaxine, according to a study published online Sept. 12 in the Journal of Clinical Oncology.

Abstract
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Editorial

Intrauterine Device Use Tied to Lower Cervical Cancer Risk

TUESDAY, Sept. 13 (HealthDay News) -- Intrauterine device (IUD) use is associated with a lower risk of cervical cancer, but the protective association is not seen in human papillomavirus (HPV)-positive women, according to a study published online Sept. 13 in The Lancet Oncology.

Abstract
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Hospitalizations for Eating Disorders Up Over Last Decade

MONDAY, Sept. 12 (HealthDay News) -- Although hospitalizations with a principal or secondary eating-disorder diagnosis increased by 24 percent from 1999-2000 to 2008-2009, there has been a decrease in hospitalizations with a principal diagnosis of eating disorder from 2007-2008 to 2008-2009, according to a statistical brief based on data from the Healthcare Cost and Utilization Project (HCUP) published online Sept. 8 by the Agency for Healthcare Research and Quality (AHRQ).

Report

Vaginal Intercourse Predicts Gynecological Exam Behavior

MONDAY, Sept. 12 (HealthDay News) -- Vaginal intercourse behavior during the past three months is the primary predictor of gynecological exam behavior among college women, according to a study published in the September issue of The Journal of Sexual Medicine.

Abstract
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Gestational Diabetes + Obesity Upregulates Endothelial Lipase

MONDAY, Sept. 12 (HealthDay News) -- Pregnancies complicated by obesity and gestational diabetes mellitus (GDM) show upregulated endothelial lipase (EL) expression, according to a study published online Aug. 18 in Diabetes.

Abstract
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Persistent Asthma Diagnosis Tied to Late-Preterm Birth

MONDAY, Sept. 12 (HealthDay News) -- Late preterm birth is correlated with an increased diagnosis of persistent asthma, use of inhaled corticosteroids, and more acute respiratory visits, according to a study published online Sept. 12 in Pediatrics.

Abstract
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Earlier Cancer Onset in Second Generation BRCA Carriers

MONDAY, Sept. 12 (HealthDay News) -- Women who are carriers of BRCA mutations for breast or ovarian cancer are more likely to be diagnosed with cancer at an earlier age than members of the previous generation, according to a study published online Sept. 12 in Cancer.

Abstract
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Moderate Drinking at Midlife Improves Aging for Women

FRIDAY, Sept. 9 (HealthDay News) -- Regular and moderate alcohol consumption in midlife is associated with successful aging in women who survive to older ages, according to a study published online Sept. 6 in PLoS Medicine.

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Child's Death Ups Mortality Risk in Bereaved Parents

FRIDAY, Sept. 9 (HealthDay News) -- Parents experiencing stillbirth or death of an infant during the first year of life (bereaved parents) have a significantly increased risk of mortality up to an average of 25 years compared with non-bereaved parents, according to a study published online Sept. 1 in BMJ: Supportive & Palliative Care.

Abstract
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Loci in ILR6, Chromosome 11q13.5 Tied to Asthma Risk

FRIDAY, Sept. 9 (HealthDay News) -- Two genetic loci in the interleukin-6 receptor (ILR6) gene and on chromosome 11q13.5 near the leucine-rich repeat containing 32 gene (LRRC32) are associated with asthma risk; and a validated exhaled nitric oxide (FENO) treatment algorithm reduces asthma exacerbations in pregnant women, according to two studies published Sept. 10 in the special European Respiratory Society issue of The Lancet.

Abstract - Ferreira
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Abstract - Powell
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Oxycodone No Safer Than Codeine During Breastfeeding

FRIDAY, Sept. 9 (HealthDay News) -- Neonates breastfed by mothers with postpartum oxycodone exposure have a higher incidence of central nervous system (CNS) depression than neonates breastfed by mothers exposed to codeine, according to a study published online Sept. 1 in The Journal of Pediatrics.

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CDC Emphasizes Importance of Flu Vaccine for Pregnant Women

THURSDAY, Sept. 8 (HealthDay News) -- Influenza can result in dire outcomes for pregnant women and their newborns; proper vaccination and early treatment are critical for optimizing maternal and offspring health, according to a report published in the Sept. 9 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Cytology Detects Proportion of Cervical Cancer Recurrence

THURSDAY, Sept. 8 (HealthDay News) -- Liquid-based cytology detects cervical cancer recurrence in about one-third of patients treated for cervical cancer; and, in the absence of any visible lesions, colposcopy is not indicated for follow-up of patients with atypical squamous cells of uncertain significance (ASC-US) or low-grade squamous intraepithelial lesions (LSIL), unless abnormalities persist, according to a study published in the September issue of Obstetrics & Gynecology.

Abstract
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Commercial Program Offers More Weight Loss Than Standard Care

THURSDAY, Sept. 8 (HealthDay News) -- Obese or overweight participants in a commercial weight loss program lose twice as much weight over a 12 month period than those in standard treatment, according to a study published online Sept. 8 in The Lancet.

Abstract
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Cardiac Mortality Rates in Women Progress at Constant Rate

THURSDAY, Sept. 8 (HealthDay News) -- Heart disease mortality rates in women progress at a constant rate as they age, which contradicts the belief that the risk of cardiovascular death for women increases sharply after menopause, according to a study published online Sept. 6 in BMJ.

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Concentration of Maternal Ether Linked to Birth Weight

THURSDAY, Sept. 8 (HealthDay News) -- Concentrations of polybrominated diphenyl ethers (PBDEs) in maternal serum during pregnancy are associated with low infant birth weight, but no association is seen with birth length, head circumference, or gestational duration, according to a study published online Aug. 30 in the American Journal of Epidemiology.

Abstract
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Post-Breast Reduction Weight Loss Tied to Shape Discontent

THURSDAY, Sept. 8 (HealthDay News) -- Most patients undergoing reduction mammaplasty before massive weight loss are initially satisfied with the results of breast appearance, but after weight loss, they are dissatisfied with the breast contour and shape, according to a study published in the September issue of Plastic and Reconstructive Surgery.

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Smoking Ups Postmenopausal Sex Hormone Levels

THURSDAY, Sept. 8 (HealthDay News) -- Postmenopausal women who smoke have increased levels of androgens, estrogens, 17-hydroxprogesterone, and sex hormone-binding globulin (SHBG), according to a study published online Aug. 10 in the Journal of Clinical Endocrinology & Metabolism.

Abstract
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Prenatal Program Reduces Obsessive Compulsive Disorder

THURSDAY, Sept. 8 (HealthDay News) -- Expectant mothers at risk for developing postpartum obsessive compulsive symptoms (OCS) show lower postpartum levels of obsessions and compulsions after undergoing a cognitive-behavioral prevention program as part of childbirth education classes, according to a study published online July 18 in the Journal of Psychiatric Research.

Abstract
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Comparative Efficacy Proposed for European Drug Approval

WEDNESDAY, Sept. 7 (HealthDay News) -- New drugs should be compared with existing treatments instead of placebo before their approval in Europe, according to a report published online Sept. 6 in the BMJ.

Abstract
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BMI of 25 or More Ups Mortality Among Black Women

WEDNESDAY, Sept. 7 (HealthDay News) -- For black women, the risk of death from any cause increases with an increasing body mass index (BMI) of 25.0 kg/m² or higher, and having a large waist circumference is associated with an increased risk of death among non-obese women, according to a study published in the Sept. 8 issue of the New England Journal of Medicine.

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Medical Students Show Racial, Cultural Patient Preference

WEDNESDAY, Sept. 7 (HealthDay News) -- Medical students may have a preferential bias toward whites and wealthier patients, but this does not appear to influence their clinical decision making or physician-patient interactions, according to a study published in the Sept. 7 medical education-themed issue of the Journal of the American Medical Association.

Abstract
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Age, Tumor Size Ups Mortality for Most Women With Breast CA

WEDNESDAY, Sept. 7 (HealthDay News) -- For most women with breast cancer who are node negative and have estrogen receptor-positive and/or progesterone receptor-positive tumors, mortality risk is associated with age and tumor size, according to a study published online Aug. 31 in the Journal of the National Cancer Institute.

Abstract
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Editorial

Gestational NSAID Intake Tied to Spontaneous Abortion Risk

WEDNESDAY, Sept. 7 (HealthDay News) -- Exposure to any type or dosage of nonaspirin nonsteroidal anti-inflammatory drug (NSAID) in early pregnancy increases the risk of spontaneous abortion, according to a study published online Sept. 6 in CMAJ, the journal of the Canadian Medical Association.

Abstract
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Odds of Board Certification Vary in New Doctors

WEDNESDAY, Sept. 7 (HealthDay News) -- Certification of recent U.S. medical school graduates by the American Board of Medical Specialties (ABMS) varies across specialties by educational and demographic factors, according to a study published in the Sept. 7 medical education-themed issue of the Journal of the American Medical Association.

Abstract
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Many Hospital Staff Uniforms Contaminated With Bacteria

WEDNESDAY, Sept. 7 (HealthDay News) -- More than 60 percent of hospital staff uniforms are contaminated with potentially pathogenic bacteria, including drug-resistant species, according to a study published in the September issue of the American Journal of Infection Control.

Abstract
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Physical Activity in Adulthood Ups Midlife Performance

MONDAY, Sept. 5 (HealthDay News) -- Physical activity across adulthood has cumulative benefits on physical performance in midlife, according to a study published in the October issue of the American Journal of Preventive Medicine.

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Sexual Satisfaction, Quality of Life Tied to Successful Aging

FRIDAY, Sept. 2 (HealthDay News) -- Although sexual activity and function decline with age, self-rated successful aging and quality of life are positively correlated with sexual measures in older postmenopausal women, according to a study published in the August issue of the Journal of the American Geriatrics Society.

Abstract
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High Adiposity Tied to Fewer Hot Flashes in Older Women

FRIDAY, Sept. 2 (HealthDay News) -- Having a higher body mass index (BMI) and waist circumference is associated with fewer physiologically measured hot flashes in older postmenopausal women with hot flashes, according to a study published online July 21 in the Journal of Clinical Endocrinology & Metabolism.

Abstract
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More Urinary Urgency, Frequency in Women Smokers

FRIDAY, Sept. 2 (HealthDay News) -- Smoking is associated with increased urinary urgency and frequency, but not with nocturia and stress urinary incontinence (SUI) in women, according to a study published in the September issue of Obstetrics & Gynecology.

Abstract
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Photodynamic Therapy Cost-Effective for High-Grade CIN

FRIDAY, Sept. 2 (HealthDay News) -- In Germany, photodynamic therapy (PDT) using hexylaminolevulinate (HAL) has the potential to be a more cost-effective treatment for high-grade cervical intraepithelial neoplasia (CIN) than conization, and implementation of PDT may reduce perinatal morbidity and associated costs, according to a study published in the September issue of Lasers in Surgery and Medicine.

Abstract
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Fewer Male Infants Being Circumcised in U.S. Hospitals

THURSDAY, Sept. 1 (HealthDay News) -- The practice of circumcising newborn males in U.S. hospitals, which increased from the late 1980s to about 2000, appears to be on the wane, according to a report published in the Sept. 2 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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