Here are what the editors at HealthDay consider to be the most important developments in Dermatology for October 2011. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Switching From IV to Oral Meds Cuts Health Care Costs
MONDAY, Oct. 31 (HealthDay News) -- For patients who are clinically eligible for oral (PO) medication intake, switching from intravenous (IV) to oral medication can substantially reduce the annual cost of health care, according to a study published online Oct. 17 in Clinical Therapeutics.
Briakinumab More Effective Than Methotrexate in Psoriasis
THURSDAY, Oct. 27 (HealthDay News) -- For patients with moderate to severe psoriasis, briakinumab is more effective than methotrexate, although serious infections and cancers occur more frequently with briakinumab, according to a study published in the Oct. 27 issue of the New England Journal of Medicine.
Ghost Authorship Prevalent in About One-Fifth of Articles
WEDNESDAY, Oct. 26 (HealthDay News) -- The prevalence of articles with honorary authorship, ghost authorship, or both is 21 percent, which marks a significant decrease since 1996, according to a study published online Oct. 25 in BMJ.
Excision Margin of 2 cm Safe in Melanoma Thicker Than 2 mm
MONDAY, Oct. 24 (HealthDay News) -- For patients with cutaneous melanoma thicker than 2 mm, a surgical excision margin of 2 cm is sufficient and has similar overall survival as with a 4-cm excision margin, according to a study published online Oct. 24 in The Lancet.
Vulvar Lesions Should Always Be Indication for Treatment
FRIDAY, Oct. 20 (HealthDay News) -- Vulvar intraepithelial neoplasia (VIN), a problem that appears to be on the rise in women in their 40s, should always receive treatment, according to a joint committee opinion issued by the American College of Obstetricians and Gynecologists and the American Society for Colposcopy and Cervical Pathology and published in the November issue of Obstetrics & Gynecology.
Article Collection Sheds Light on U.S. Melanoma Trends
THURSDAY, Oct. 20 (HealthDay News) -- Skin cancer is the most common form of cancer in the United States, and melanoma, the third-most common form of skin cancer, may strike more than 45,000 people annually, according to a recent supplement published in the November issue of the Journal of the American Academy of Dermatology.
Platelet-Rich Fibrin Matrix Shots Induce Cellular Changes
THURSDAY, Oct. 20 (HealthDay News) -- Administration of platelet-rich fibrin matrix (PRFM) into the deep dermis and immediate subdermis stimulates cellular changes, including activated fibroblasts, new collagen deposition, new blood vessel development, intradermal adipocyte collection, and subdermal adipocyte stimulation, according to a study published online Oct. 17 in the Archives of Facial Plastic Surgery.
Low Lethal Potential for Atypical Spitz Tumors
THURSDAY, Oct. 20 (HealthDay News) -- Atypical Spitz tumors (ASTs) are associated with a favorable prognosis, an increased melanoma risk, and a moderate risk of metastasis to regional nodes, according to a study published in the October issue of the Archives of Dermatology.
Deletion in ADAM17 Connected to Skin, Bowel Disease
WEDNESDAY, Oct. 19 (HealthDay News) -- A deletion mutation in ADAM17 may be the cause of a neonatal-onset inflammatory skin and bowel disease, according to a study published in the Oct. 20 issue of the New England Journal of Medicine.
Distinct Risks for Superficial Spreading, Lentigo Melanomas
WEDNESDAY, Oct. 19 (HealthDay News) -- Lentigo maligna melanoma (LMM) and superficial spreading melanoma (SSM) have distinct risk profiles, with the strongest determinants of LMM and SSM being the number of solar lentigines and the number of nevi, respectively, according to a study published online Oct. 17 in the Archives of Dermatology.
Hair Professionals Are Potential Skin Cancer Educators
TUESDAY, Oct. 18 (HealthDay News) -- A considerable proportion of hair professionals are looking for lesions on their customers' scalp, neck, and face; and their personal self-reported health communication practices are significantly associated with the frequency of observation of lesions, according to a study published in the October issue of the Archives of Dermatology.
Readmission Risk Models Display Poor Predictive Ability
TUESDAY, Oct. 18 (HealthDay News) -- Most hospital readmission risk models have poor predictive ability, according to a review published in the Oct. 19 issue of the Journal of the American Medical Association.
Alopecia Areata Linked With Other Autoimmune Diseases
MONDAY, Oct. 17 (HealthDay News) -- Alopecia areata (AA) appears to be associated with various autoimmune diseases, which vary according to age at onset of AA, according to research published in the November issue of the Journal of the American Academy of Dermatology.
Rare Disorders ID'd by NIH Undiagnosed Diseases Program
THURSDAY, Oct. 13 (HealthDay News) -- The extensive application of genomic technology under the U.S. National Institutes of Health Undiagnosed Diseases Program (NIH-UDP) helps diagnose complex and rare multisystem disorders, according to a report published online Sept. 26 in Genetics in Medicine.
Financial Conflicts of Interest Prevalent, Under-Reported
WEDNESDAY, Oct. 12 (HealthDay News) -- Conflicts of interest (COI) are prevalent among members and chairs of guideline panels, and are under-reported, according to a study published online Oct. 11 in BMJ.
Electronic Records Enhance Care Transitions for Elderly
MONDAY, Oct. 10 (HealthDay News) -- Implementation of electronic health care record (EHR) systems is likely to enhance communication and patient care during care transitions, particularly for older patients, according to a study published in the October issue of the AORN Journal.
UVA1 Induces Thymine Dimers in DNA of Human Skin in Vivo
FRIDAY, Oct. 7 (HealthDay News) -- Ultraviolet A1 (UVA1) rays induce thymine dimers (TTs) but not pyrimidine (6-4) pyrimidone photoproducts (6-4PPs) in the DNA of human epidermis in vivo, and the level of induced TTs increases with the epidermal depth, according to a study published online Oct. 6 in the Journal of Investigative Dermatology.
Use of Oral Steroids Linked to Vitamin D Deficiency
THURSDAY, Oct. 6 (HealthDay News) -- The use of oral steroids is associated with serum 25-hydroxyvitamin D (25[OH]D) deficiency, according to a study published online Sept. 28 in the Journal of Clinical Endocrinology & Metabolism.
Fractional Lasers Effective, Safe in Dark-Skin Acne Scars
WEDNESDAY, Oct. 5 (HealthDay News) -- Non-ablative fractional (NAF) 1,550 nm and ablative fractional (AF) CO2 lasers are effective and safe for treating acne scars in ethnic skin, with a good patient satisfaction rate, according to a study published in the September issue of Lasers in Surgery and Medicine.
Vitamin D Insufficiency Prevalent in Psoriatic Arthritis
MONDAY, Oct. 3 (HealthDay News) -- Vitamin D insufficiency appears to be highly prevalent among people with psoriatic arthritis (PsA), regardless of where they live or the time of year, according to research published in the October issue of Arthritis Care & Research.
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