Here are what the editors at HealthDay consider to be the most important developments in Psychiatry for October 2011. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Momentary Positive Affect Tied to Improved Survival
MONDAY, Oct. 31 (HealthDay News) -- Positive affect (PA) is associated with survival, with high PA linked to considerably improved survival in older men and women, according to a study published online Oct. 31 in the Proceedings of the National Academy of Sciences.
Switching From IV to Oral Meds Cuts Health Care Costs
MONDAY, Oct. 31 (HealthDay News) -- For patients who are clinically eligible for oral (PO) medication intake, switching from intravenous (IV) to oral medication can substantially reduce the annual cost of health care, according to a study published online Oct. 17 in Clinical Therapeutics.
Universal Teen Substance Use Approach Recommended
MONDAY, Oct. 31 (HealthDay News) -- The American Academy of Pediatrics recommends implementing universal screening for substance use, brief intervention, and/or referral to treatment (SBIRT) in order to help pediatricians treat substance use in adolescents, according to a scientific statement published online Oct. 31 in Pediatrics.
Symptom Profiles Identify Unmet Child Mental Health Needs
MONDAY, Oct. 31 (HealthDay News) -- Symptom profiles have been identified that may help detect children with unmet mental health needs, according to a study published online Oct. 24 in Pediatrics.
Brain Transcriptome Reveals Gender-Biased Gene Expression
FRIDAY, Oct. 28 (HealthDay News) -- Generation and analysis of an exon-level transcriptome of the human brain and associated genotyping data shows that the transcriptome is organized into different coexpression networks, and shows gender-biased gene expression and exon usage, according to a study published in the Oct. 27 issue of Nature.
Nonclinical Factors Impact Back Pain Treatment Decisions
FRIDAY, Oct. 28 (HealthDay News) -- Nonclinical factors, including gender, socioeconomic status, and patient presentation, influence physicians' treatment recommendations for acute nonspecific low back pain, with patient presentation the most influential factor, according to a study published in the Nov. 1 issue of Spine.
IBS Patient-Reported Outcomes Tied to Symptom Severity Ratings
FRIDAY, Oct. 28 (HealthDay News) -- Pain catastrophizing and somatization affect patients' judgments of pain, bloating, and/or bowel habits, which impact patient-reported outcomes (PROs) in irritable bowel syndrome (IBS), according to a study published in the November issue of Clinical Gastroenterology and Hepatology.
Weight Loss in Obese Tied to Low-Order Cognitive Upturn
FRIDAY, Oct. 28 (HealthDay News) -- Weight loss in obese individuals is associated with low-order significant improvements in executive/attention functioning and memory, according to a meta-analysis published in the November issue of Obesity Reviews.
Cannabinoid Receptor Tied to Cognitive Chaos
THURSDAY, Oct. 27 (HealthDay News) -- Disrupted temporal coordination of hippocampal and medial prefrontal cortical networks (mPFC) due to systemic activation of the cannabinoid receptor is associated with impaired accuracy during working-memory task performance in rats, according to an experimental study published in the Oct. 26 issue of the Journal of Neuroscience.
Bedside Geriatric Assessment Feasible in Elderly With AML
THURSDAY, Oct. 27 (HealthDay News) -- Inpatient bedside geriatric assessment (GA) is feasible, and is useful for identifying multiple geriatric impairments in elderly patients initiating chemotherapy for acute myelogenous leukemia (AML), according to a study published in the October issue of the Journal of the American Geriatrics Society.
Gene Variation Tied to Rate of Age-Related Mental Decline
THURSDAY, Oct. 27 (HealthDay News) -- A valine-to-methionine substitution at position 66 (val66met) of brain-derived neurotrophic factor (BDNF) is associated with the rate of decline in skilled task performance and age-dependent hippocampal volume changes in middle-aged and older healthy individuals, according to a study published online Oct. 25 in Translational Psychiatry.
Similar Clinical Impairments for Men, Women Who Binge Eat
THURSDAY, Oct. 27 (HealthDay News) -- Men and women who binge eat suffer similar levels of clinical impairment, despite an underrepresentation of men in treatment studies, according to a study published online Oct. 26 in the International Journal of Eating Disorders.
Long-Term Moderate, High Stress Ups Male Mortality Rate
THURSDAY, Oct. 27 (HealthDay News) -- Long-term moderate or high levels of stress in men are associated with higher mortality rates, independent of demographics and health behavior habits, according to a study published in the Journal of Aging Research.
Ghost Authorship Prevalent in About One-Fifth of Articles
WEDNESDAY, Oct. 26 (HealthDay News) -- The prevalence of articles with honorary authorship, ghost authorship, or both is 21 percent, which marks a significant decrease since 1996, according to a study published online Oct. 25 in BMJ.
Drinking Non-Diet Soda Tied to Violent Behavior Among Teens
WEDNESDAY, Oct. 26 (HealthDay News) -- Soft drink consumption among adolescents is significantly associated with weapon possession and with perpetration of violence against peers, family members, and dates, according to a study published online Oct. 24 in Injury Prevention.
Mortgage Default Associated With Worse Health Status
TUESDAY, Oct. 25 (HealthDay News) -- Falling behind in mortgage payments is correlated with elevated depressive symptoms, food insecurity, and cost-related medication nonadherence, according to a study published online Oct. 20 in the American Journal of Public Health.
First Versions of Generic Zyprexa Approved
MONDAY, Oct. 24 (HealthDay News) -- The first generic versions of Zyprexa (olanzapine) have been approved by the U.S. Food and Drug Administration to treat schizophrenia or bipolar disorder, the agency said Monday.
Insomnia Moderately Raises Risk of Myocardial Infarction
MONDAY, Oct. 24 (HealthDay News) -- Insomnia symptoms are associated with a moderate increase in the risk of acute myocardial infarction (AMI), according to a study published online Oct. 24 in Circulation.
Breast Reconstruction Ups Psychosocial, Sexual Health
MONDAY, Oct. 24 (HealthDay News) -- Women undergoing autologous tissue breast reconstruction experience significant gains in breast satisfaction, and psychological and sexual well-being as early as three weeks post surgery, according to a study published online Oct. 24 in Cancer.
Care for Veterans With Mental Illness Good in VA System
FRIDAY, Oct. 21 (HealthDay News) -- The Veterans Health Administration (VHA) takes relatively good care of U.S. veterans with mental illnesses and substance use disorders; however, there is regional variation in the quality of services provided, and room for improvement, according to research published online Oct. 19 in Health Affairs.
Dopamine Polymorphisms Tied to Methylphenidate Response
FRIDAY, Oct. 21 (HealthDay News) -- Dopamine transporter (DAT) and dopamine receptor D4 (DRD4) polymorphisms may be correlated with dose-response variability to methylphenidate (MPH) in children with attention-deficit/hyperactivity disorder (ADHD), according to a study published online Sept. 19 in the Journal of the American Academy of Child & Adolescent Psychiatry.
Social Network Size Associated With Brain Structure
THURSDAY, Oct. 20 (HealthDay News) -- The size of a person's online social network is associated with the gray matter density of specific regions in the brain, and these regions are specific to Web-based networks rather than real-world social networks, according to a study published online Oct. 19 in the Proceedings of the Royal Society B.
Antidepressants Used by About 11 Percent of Americans
WEDNESDAY, Oct. 19 (HealthDay News) -- Approximately one out of 10 Americans aged 12 and over take antidepressant medications, the use of which is most prevalent in women aged 40 to 59, according to an October data brief released by the National Center for Health Statistics (NCHS).
Nicotine Dependence Underdiagnosed in U.S. Vets
WEDNESDAY, Oct. 19 (HealthDay News) -- U.S. veterans are more likely than the general population to have a nicotine dependency, especially if they've struggled with other substances, mental illness, or homelessness, but VA services may be underestimating the scope of the problem, according to research published in the November issue of the U.S. Centers for Disease Control and Prevention's Preventing Chronic Disease.
Readmission Risk Models Display Poor Predictive Ability
TUESDAY, Oct. 18 (HealthDay News) -- Most hospital readmission risk models have poor predictive ability, according to a review published in the Oct. 19 issue of the Journal of the American Medical Association.
Autism More Prevalent in Low Birth Weight Individuals
MONDAY, Oct. 17 (HealthDay News) -- Low birth weight (LBW) has been considered a risk for autism spectrum disorders (ASDs), and the results of a new prospective study suggest ASDs are indeed more prevalent in people born at low birth weights; the findings have been published online Oct. 17 in Pediatrics.
Pediatric MRI Meets Minimum-Risk Standards
THURSDAY, Oct. 13 (HealthDay News) -- Use of magnetic resonance imaging (MRI) in pediatric clinical trials meets the minimum-risk standard for physical and psychological injury, but addition of contrast dye or sedation increases the risks, according to a report published in the September-October issue of IRB: Ethics & Human Research.
Rare Disorders ID'd by NIH Undiagnosed Diseases Program
THURSDAY, Oct. 13 (HealthDay News) -- The extensive application of genomic technology under the U.S. National Institutes of Health Undiagnosed Diseases Program (NIH-UDP) helps diagnose complex and rare multisystem disorders, according to a report published online Sept. 26 in Genetics in Medicine.
One in Five With Cerebral Glioma Develops Depression
THURSDAY, Oct. 13 (HealthDay News) -- Approximately 20 percent of patients with cerebral glioma have major depressive disorder (MDD) in the six months after starting radiotherapy, with a previous history of functional impairment or depression predicting MDD, according to a study published online Oct. 11 in the Journal of Clinical Oncology.
PTSD Symptoms Persist in Some Long-Term NHL Survivors
WEDNESDAY, Oct. 12 (HealthDay News) -- More than one third of the long-term survivors of non-Hodgkin's lymphoma (NHL) experience persistence or worsening of the symptoms of post-traumatic stress disorder (PTSD), according to a study published online Oct. 11 in the Journal of Clinical Oncology.
Financial Conflicts of Interest Prevalent, Under-Reported
WEDNESDAY, Oct. 12 (HealthDay News) -- Conflicts of interest (COI) are prevalent among members and chairs of guideline panels, and are under-reported, according to a study published online Oct. 11 in BMJ.
Women Remain Distress-Free Long After Genetic Test Results
TUESDAY, Oct. 11 (HealthDay News) -- Most women do not experience distress several years after receiving BRCA1 and BRCA2 (BRCA1/2) genetic test results, but mutation carriers are significantly more likely to experience distress, according to a study published online Oct. 10 in the Journal of Clinical Oncology.
Men With Disabilities More Likely to Be Sexually Abused
TUESDAY, Oct. 11 (HealthDay News) -- Men with disabilities have an increased risk of lifetime and past-year sexual violence victimization, compared to men without disabilities, according to a study published online Oct. 11 in the American Journal of Preventive Medicine.
Plasma Sphingolipids Predict Alzheimer's Progression
FRIDAY, Oct. 7 (HealthDay News) -- Higher plasma levels of ceramides, dihydroceramides (DHCer), sphingomyelins (SM), and dihydrosphingomyelins (DHSM), and ratios of SM/ceramide and DHSM/DHCer are associated with progression in Alzheimer's disease (AD), according to a study published online Aug. 12 in the Journal of Alzheimer's Disease.
Prevalence of Sexual Abuse ID'd in Urological Patients
FRIDAY, Oct. 7 (HealthDay News) -- The prevalence of sexual abuse (SA) in patients seeking urological care in the Netherlands is 2.1 percent for men and 13.0 percent for women, according to a study published in the October issue of The Journal of Sexual Medicine.
Two HIV Variants Identified in HIV-Linked Dementia
FRIDAY, Oct. 7 (HealthDay News) -- Individuals with HIV-type 1 (HIV-1)-associated dementia (HAD) have two genetically distinct HIV-1 variants in their cerebrospinal fluid (CSF): CCR5-tropic (R5) T-cell-tropic and macrophage-tropic, which differ in terms of replication and evolution in the central nervous system (CNS), according to a study published online Oct. 6 in PLoS Pathogens.
Adults With Mental Distress More Likely to Be Uninsured
FRIDAY, Oct. 7 (HealthDay News) -- Lack of insurance is more likely among nonelderly adults in the United States with frequent mental distress only or with both frequent mental and physical distress than in those with frequent physical distress only, according to a study published in the October issue of Psychiatric Services.
Psychotherapy Service Cuts Health Care Use, Sick Leave
THURSDAY, Oct. 6 (HealthDay News) -- Individuals with common mental health problems (CMHP) use more health care resources, and referral to the Improving Access to Psychological Therapies (IAPT) program reduces their number of emergency department visits and sick days, according to a study published online Oct. 3 in the Journal of Epidemiology & Community Health.
Prolonged Exposure, Cognitive Therapy Prevent Chronic PTSD
THURSDAY, Oct. 6 (HealthDay News) -- Prolonged exposure (PE), delayed PE, and cognitive therapy (CT) reduce the prevalence of chronic post-traumatic stress disorder (PTSD) in survivors of traumatic events, according to a study published online Oct. 3 in the Archives of General Psychiatry.
Self-Rating of Health As Poor, Fair Ups Risk of Dementia
WEDNESDAY, Oct. 5 (HealthDay News) -- The risk of incident dementia is significantly higher in individuals who rate their health as poor or fair, especially in those with no cognitive complaints or with functional disability, according to a study published online Oct. 5 in Neurology.
5-HTTLPR Gene Linked to Positive Affect in Youth
WEDNESDAY, Oct. 5 (HealthDay News) -- Youth carrying two short alleles of 5-HTTLPR are more susceptible to parenting as environmental context, according to a study published online Oct. 4 in Translational Psychiatry.
Head Circumference Growth Up in Infancy in Boys With Autism
WEDNESDAY, Oct. 5 (HealthDay News) -- Boys with autism experience accelerated head circumference (HC) growth, and have increased height and weight in the first year of life, according to a study published in the October issue of the Archives of General Psychiatry.
Eating Disorders in Children Tied to Serious Health Consequences
WEDNESDAY, Oct. 5 (HealthDay News) -- The incidence of early-onset restrictive eating disorders is 2.6 cases per 100,000 person-years in children, is increased in girls, and can result in serious medical consequences, according to a study published in the October issue of the Archives of Pediatrics & Adolescent Medicine.
Alcohol-Impaired Driving Down by 30 Percent in U.S.
TUESDAY, Oct. 4 (HealthDay News) -- U.S. adults drive after drinking "a bit too much" about a third less often than they did in 2006; still, about 1.8 percent of adults (four million people) reported alcohol-impaired driving in 2010, according to a report in the Oct. 4 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.
Clinically Meaningful Weight Loss From Behavioral Therapy
TUESDAY, Oct. 4 (HealthDay News) -- Although health-outcome data are sparse, behavioral interventions are effective in yielding clinically meaningful weight loss in overweight and obese individuals, according to a study published in the Oct. 4 issue of the Annals of Internal Medicine.
Flibanserin Effective Therapy for Hypoactive Sexual Desire
MONDAY, Oct. 3 (HealthDay News) -- Flibanserin is a safe and effective treatment for premenopausal women with hypoactive sexual desire disorder (HSDD), according to a study published online Sept. 20 in The Journal of Sexual Medicine.
Early Anesthesia Exposures Tied to Learning Disabilities
MONDAY, Oct. 3 (HealthDay News) -- Exposure to multiple anesthesia/surgery before the age of 2 years is a significant risk factor for the development of learning disabilities (LDs) later in life, but not for the receipt of an individualized education program for an emotional/behavior disorder (IEP-EBD), according to a study published online Oct. 3 in Pediatrics.
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