Here are what the editors at HealthDay consider to be the most important developments in Nephrology for October 2011. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Switching From IV to Oral Meds Cuts Health Care Costs
MONDAY, Oct. 31 (HealthDay News) -- For patients who are clinically eligible for oral (PO) medication intake, switching from intravenous (IV) to oral medication can substantially reduce the annual cost of health care, according to a study published online Oct. 17 in Clinical Therapeutics.
Bedtime Medications Offer Better BP Control in CKD
WEDNESDAY, Oct. 26 (HealthDay News) -- For patients with chronic kidney disease (CKD), taking at least one hypertension medication at bedtime results in better blood pressure (BP) control compared to morning medication, according to a study published online Oct. 24 in the Journal of the American Society of Nephrology.
Ghost Authorship Prevalent in About One-Fifth of Articles
WEDNESDAY, Oct. 26 (HealthDay News) -- The prevalence of articles with honorary authorship, ghost authorship, or both is 21 percent, which marks a significant decrease since 1996, according to a study published online Oct. 25 in BMJ.
New Method Improves Renal Transplant Biopsy Accuracy
MONDAY, Oct. 24 (HealthDay News) -- Adding molecular phenotyping to histological classification of kidney transplantation biopsies facilitates more accurate classification of borderline rejection biopsies, and helps eliminate this category in most cases, according to a study published online Oct. 12 in the American Journal of Transplantation.
Successful Pregnancy Feasible After Kidney Transplantation
MONDAY, Oct. 24 (HealthDay News) -- Pregnancy after kidney transplantation is associated with an increased live birth rate, lower miscarriage rate, and higher rate of complications compared to the general U.S. population, according to a study published online July 27 in the American Journal of Transplantation.
Sodium-Sensitive Populations Fail to Curb Intake
THURSDAY, Oct. 20 (HealthDay News) -- Nearly half of all Americans should limit their sodium intake for the sake of their health, but less than 2 percent of those who meet the criteria for sodium limitation actually do so, and most Americans ingest too much sodium, according to research published in the Oct. 21 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.
Readmission Risk Models Display Poor Predictive Ability
TUESDAY, Oct. 18 (HealthDay News) -- Most hospital readmission risk models have poor predictive ability, according to a review published in the Oct. 19 issue of the Journal of the American Medical Association.
E-Beam Sterilized Dialyzers Up Risk of Thrombocytopenia
TUESDAY, Oct. 18 (HealthDay News) -- Use of electron-beam (e-beam) sterilized hemodialysis membranes increases the risk of significant thrombocytopenia, according to a study published in the Oct. 19 issue of the Journal of the American Medical Association.
Single Kidney Outcome Similar With Nephrectomy, Ablation
MONDAY, Oct. 17 (HealthDay News) -- For patients with a tumor in a solitary kidney, short-term renal function outcomes are similar for treatment with partial nephrectomy or percutaneous ablation, according to a study published in the November issue of The Journal of Urology.
Rare Disorders ID'd by NIH Undiagnosed Diseases Program
THURSDAY, Oct. 13 (HealthDay News) -- The extensive application of genomic technology under the U.S. National Institutes of Health Undiagnosed Diseases Program (NIH-UDP) helps diagnose complex and rare multisystem disorders, according to a report published online Sept. 26 in Genetics in Medicine.
Financial Conflicts of Interest Prevalent, Under-Reported
WEDNESDAY, Oct. 12 (HealthDay News) -- Conflicts of interest (COI) are prevalent among members and chairs of guideline panels, and are under-reported, according to a study published online Oct. 11 in BMJ.
Septicemia Most Costly Reason for Hospitalization in 2009
MONDAY, Oct. 10 (HealthDay News) -- Septicemia was the single most expensive condition treated in U.S. hospitals in 2009, with expenditure totaling nearly $15.4 billion, according to an October statistical brief based on Healthcare Cost and Utilization Project (HCUP) data published by the Agency for Healthcare Research and Quality (AHRQ).
Recurrent Child UTIs Rarely Cause Chronic Kidney Disease
MONDAY, Oct. 10 (HealthDay News) -- The etiologic fraction of recurrent urinary tract infections (UTIs) as the main cause of chronic kidney disease (CKD) is very small, according to a study published online Oct. 10 in Pediatrics.
Elevated Liver Function Enzymes Tied to Diabetes Risk
MONDAY, Oct. 10 (HealthDay News) -- Elevated liver alanine aminotransferase (ALT) and γ-glutamyl transferase (GGT) are potentially useful for predicting the risk of young adults developing diabetes, according to a study published online Sept. 27 in Diabetes Care.
Multiple Benefits From Regular Exercise in Renal Disease
FRIDAY, Oct. 7 (HealthDay News) -- Regular exercise significantly improves physical fitness, cardiovascular dimensions, some nutritional parameters, and health-related quality of life (QOL) in adults with chronic kidney disease (CKD) and kidney transplant recipients, according to a review and meta-analysis published online Oct. 5 in the Cochrane Database of Systematic Reviews.
More Minority Patients in Low-Quality, High-Cost Hospitals
THURSDAY, Oct. 6 (HealthDay News) -- Hospitals where the quality is low and costs high (worst hospitals) in the United States care for a higher proportion of elderly black, Hispanic, and Medicaid patients than high-quality, low-cost institutions (best hospitals), according to a study published in the October issue of Health Affairs.
Feasible to Stop Post-Renal Transplant Anti-Rejection Meds
WEDNESDAY, Oct. 5 (HealthDay News) -- Most patients undergoing human leukocyte antigen (HLA)-matched kidney-transplantation are able to discontinue anti-rejection medications, after receiving enriched CD34+ hematopoietic progenitor cells, total lymphoid irradiation, and anti-T-cell antibodies, according to a letter published in the Oct. 6 issue of the New England Journal of Medicine.
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