Create Account | Sign In: Author or Forum

 
 
News  |  Journals  |  Conferences  |  Blogs  |  Articles  |  Forums  |  Twitter    
 

 Headlines:

 

Category: Family Medicine | Gynecology | Internal Medicine | Neurology | Nursing | Pharmacy | Psychiatry | Rheumatology | Anesthesiology & Pain | Conference News

Back to Journal Articles

SfN: Exercise Tied to Neuronal Changes in Fibromyalgia

Last Updated: November 14, 2011.

 

Increased pain sensation following medication withdrawal is improved by aerobic exercise

Share |

Comments: (0)

Tell-a-Friend

 

  Related
 
For patients with fibromyalgia, implementation of an aerobic exercise program after medication cessation increases neuronal activity in areas of the brain related to a memory task and decreases pain sensation, according to a study presented at the annual meeting of the Society for Neuroscience, held from Nov. 12 to 16 in Washington, D.C.

MONDAY, Nov. 14 (HealthDay News) -- For patients with fibromyalgia, implementation of an aerobic exercise program after medication cessation increases neuronal activity in areas of the brain related to a memory task and decreases pain sensation, according to a study presented at the annual meeting of the Society for Neuroscience, held from Nov. 12 to 16 in Washington, D.C.

Brian Walitt, M.D., from Georgetown University Medical Center in Washington D.C., and colleagues assessed the effect of aerobic exercise on working memory in nine women with fibromyalgia. Functional magnetic resonance imaging (fMRI) was carried out at four visits: at baseline, where patients were taking fibromyalgia medications; at the washout visit, where patients were off all medications for three half lives; at six weeks after stopping medications; and after a six week aerobic exercise intervention. Data for an N-Back fMRI task were collected for each phase. Changes in neuronal activity across visits were assessed using a model related to changes in their patient global impression change (PGIC).

The investigators found that the second-level model related to PGIC changed across visits. The subjective rating of pain increased as patients discontinued their medications, and then decreased with the exercise intervention. Neuronal activity in areas recruited for the working memory task decreased following medication cessation, and then increased on later visits. Increased activation was seen in task-related areas, including the left superior medial frontal, the left dorsal lateral prefrontal, the right mid frontal, the right supplementary motor, the left thalamus, left caudate, left inferior parietal, and bilateral superior parietal regions.

"Exercise may have benefit in both reducing fibromyalgia symptoms and improving cognitive capacity," the authors write.

Abstract
More Information

Copyright © 2011 HealthDay. All rights reserved.


Previous: AHA: Childhood Abuse Predicts CVD Risk in Adult Women Next: AHA: Single AMG145 Dose Lowers LDL-Cholesterol Levels

Reader comments on this article are listed below. Review our comments policy.


Submit your opinion:

Name:

Email:

Location:

URL:

Remember my personal information

Notify me of follow-up comments?

advertisement.gif (61x7 -- 0 bytes)
 

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

  • Ask a Doctor Teams: Respond to patient questions and discuss challenging presentations with other members.

Doctors Lounge Membership Application

 
     

 advertisement.gif (61x7 -- 0 bytes)

 

 

Useful Sites
MediLexicon
  Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us
Copyright © 2001-2014
Doctors Lounge.
All rights reserved.

Medical Reference:
Diseases | Symptoms
Drugs | Labs | Procedures
Software | Tutorials

Advertising
Links | Humor
Forum Archive
CME | Conferences

Privacy Statement
Terms & Conditions
Editorial Board
About us | Email

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.