Create Account | Sign In: Author or Forum

 
 
News  |  Journals  |  Conferences  |  Blogs  |  Articles  |  Forums  |  Twitter    
 

 Headlines:

 

Category: Endocrinology | Family Medicine | Gynecology | Internal Medicine | Nursing | Pediatrics | Journal

Back to Journal Articles

Birth Weight Inversely Impacts Diabetes Risk

Last Updated: November 30, 2011.

 

More weight gain than expected from 48 months to adulthood tied to impaired fasting glucose, diabetes

Share |

Comments: (0)

Tell-a-Friend

 

  Related
 
Birth weight is inversely associated with adult fasting-glucose levels and with the risk of impaired fasting glucose or type 2 diabetes mellitus, according to a study published online Nov. 18 in Diabetes Care.

WEDNESDAY, Nov. 30 (HealthDay News) -- Birth weight is inversely associated with adult fasting-glucose levels and with the risk of impaired fasting glucose (IFG) or type 2 diabetes mellitus (DM), according to a study published online Nov. 18 in Diabetes Care.

Shane A. Norris, Ph.D., from the University of the Witwatersrand in Johannesburg, South Africa, and colleagues examined the associations of birth weight and weight gain in infancy and early childhood with DM risk in 6,511 young adults from low- and middle-income countries. Weight was measured at birth, at 24 and 48 months, and in adulthood, and the deviation from expected weight gain between these ages (conditional weight gain [CWG]) was calculated.

The investigators found an inverse association for birth weight with adult fasting-glucose and the risk of IFG/DM (odds ratio [OR], 0.91 per standard deviation [SD]). Weight at 24 and 48 months and CWG at 0 to 24 and 24 to 48 months were not related to fasting-glucose or IFG/DM. CWG at 48 months to adult correlated positively with IFG/DM (OR, 1.32 per SD). Birth weight, weight at 24 to 48 months, and CWG at 0 to 24 months had inverse associations with fasting-glucose and IFG/DM, after adjusting for adult waist circumference. Birth weight had no relation with insulin resistance homeostasis model assessment (IR-HOMA), but higher CWG at 0 to 24, 24 to 48, and 48 months to adult predicted significantly higher IR-HOMA. Birth weight had an inverse association with IR-HOMA after adjusting for adult waist circumference.

"Lower birth weight and accelerated weight gain after 48 months are risk factors for adult glucose intolerance," the authors write.

Abstract
Full Text (subscription or payment may be required)

Copyright © 2011 HealthDay. All rights reserved.


Previous: U.S. Patients Highly Satisfied With Outpatient Medical Care Next: 3-D MRI Differentiates Benign, Malignant Lesions Accurately

Reader comments on this article are listed below. Review our comments policy.


Submit your opinion:

Name:

Email:

Location:

URL:

Remember my personal information

Notify me of follow-up comments?

advertisement.gif (61x7 -- 0 bytes)
 

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

  • Ask a Doctor Teams: Respond to patient questions and discuss challenging presentations with other members.

Doctors Lounge Membership Application

 
     

 advertisement.gif (61x7 -- 0 bytes)

 

 

Useful Sites
MediLexicon
  Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us
Copyright © 2001-2014
Doctors Lounge.
All rights reserved.

Medical Reference:
Diseases | Symptoms
Drugs | Labs | Procedures
Software | Tutorials

Advertising
Links | Humor
Forum Archive
CME | Conferences

Privacy Statement
Terms & Conditions
Editorial Board
About us | Email

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.