Create Account | Sign In: Author or Forum

 
News  |  Journals  |  Conferences  |  Opinion  |  Articles  |  Forums  |  Twitter    
 
Category: Pathology | Monthly Briefing

Back to Journal Articles

November 2011 Briefing - Pathology

Last Updated: December 01, 2011.

 

Share |

Comments: (0)

Tell-a-Friend

 

  Related
 

Here are what the editors at HealthDay consider to be the most important developments in Pathology for November 2011. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

3-D MRI Differentiates Benign, Malignant Lesions Accurately

WEDNESDAY, Nov. 30 (HealthDay News) -- Use of three-dimensional (3D) magnetic resonance (MR) spectroscopic imaging at 3 tesla (3T) provides high sensitivity and specificity for discriminating benign and malignant breast lesions, according to a study published in the December issue of Radiology.

Abstract
Full Text (subscription or payment may be required)

Pronounced Childhood Effects Seen With MC4R Deficiency

WEDNESDAY, Nov. 30 (HealthDay News) -- The effects of melanocortin-4-receptor (MC4R) deficiency on the body mass accumulation rate are more pronounced during childhood, according to a study published online Nov. 21 in Diabetes.

Abstract
Full Text (subscription or payment may be required)

Abnormal Brain Enlargement in Boys With Regressive Autism

TUESDAY, Nov. 29 (HealthDay News) -- Boys with regressive autism have abnormal brain enlargement, with a head circumference that diverges from other groups at age 4 to 6 months, according to a study published online Nov. 28 in the Proceedings of the National Academy of Sciences.

Abstract
Full Text

Prediagnosis BMI Predicts Mortality in Patients With CRC

TUESDAY, Nov. 29 (HealthDay News) -- For patients with nonmetastatic colorectal cancer (CRC), prediagnosis, but not postdiagnosis, body mass index (BMI) is an important predictor of all-cause and cause-specific mortality; and patients with type 2 diabetes mellitus (T2DM) have a higher risk of mortality, according to two studies published online Nov. 28 in the Journal of Clinical Oncology.

Abstract - Campbell
Full Text (subscription or payment may be required)
Abstract - Dehal
Full Text (subscription or payment may be required)
Editorial

NSAID, Statin Use Cuts Cancer Risk in Barrett's Esophagus

TUESDAY, Nov. 29 (HealthDay News) -- For patients with Barrett's esophagus, use of nonsteroidal anti-inflammatory drugs (NSAIDs) and statins reduces the risk of neoplastic progression, with combined use giving additional protection, according to a study published in the December issue of Gastroenterology.

Abstract
Full Text (subscription or payment may be required)

New Treatment for Radiation Toxicities May Be Feasible

MONDAY, Nov. 28 (HealthDay News) -- In mice with extensive radiation exposure, a combination of a fluoroquinolone antibiotic and recombinant bactericidal/permeability-increasing protein fragment (rBPI21) improves survival, speeds up hematopoietic recovery, and promotes expansion of stem and progenitor cells, according to an experimental study published in the Nov. 23 issue of Science Translational Medicine.

Abstract
Full Text (subscription or payment may be required)

High-Performing Docs Learn Equally From Success, Failure

MONDAY, Nov. 28 (HealthDay News) -- Among physicians making decisions in a medically-framed learning task, high and low performers show distinct behavioral and neural patterns of learning, according to a study published online Nov. 23 in PLoS One.

Full Text

Small Cell Carcinoma of Urinary Bladder Incidence Up

MONDAY, Nov. 28 (HealthDay News) -- The incidence of small cell carcinoma of the urinary bladder (SCCB) increased from 1991 to 2005, with elderly Caucasian men being the most commonly affected, according to a study published in the Dec. 1 issue of Cancer.

Abstract
Full Text (subscription or payment may be required)

GIP Identified As Bifunctional Blood Glucose Stabilizer

MONDAY, Nov. 28 (HealthDay News) -- Infusion of glucose-dependent insulinotropic polypeptide (GIP) increases glucagon responses during hypoglycemia and euglycemia, with no effect on insulin secretion, and more than doubles the insulin secretion rate during hyperglycemia, with no effect on glucagon responses, according to a study published in the December issue of Diabetes.

Abstract
Full Text (subscription or payment may be required)

Pathologist Case Volume Affects Thyroid FNA Reading

MONDAY, Nov. 28 (HealthDay News) -- Case volume significantly affects pathologic interpretation of thyroid fine needle aspiration (FNA), but does not impact diagnostic yield, according to a study published in the November issue of the Archives of Otolaryngology -- Head & Neck Surgery.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Many Pediatricians OK With Alternative Vaccine Schedules

MONDAY, Nov. 28 (HealthDay News) -- Pediatricians in Washington State are frequently asked to use alternative childhood immunization schedules (ACISs), and the majority are comfortable using them, according to a study published online Nov. 28 in Pediatrics.

Abstract
Full Text (subscription or payment may be required)

Autoimmune Disorders Tied to Pulmonary Embolism Risk

MONDAY, Nov. 28 (HealthDay News) -- Autoimmune disorders are associated with an increased risk of pulmonary embolism, particularly during the first year after hospitalization, according to a study published online Nov. 26 in The Lancet.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Short Stature Tied to Low-Frequency, Rare Gene Deletions

MONDAY, Nov. 28 (HealthDay News) -- Short stature is associated with an increased global burden of copy-number variants (CNVs) as well as a greater average length of CNVs for lower-frequency and rare deletions, according to a report published online Nov. 23 in the American Journal of Human Genetics.

Abstract
Full Text (subscription or payment may be required)

Stem-Cell-Seeded Bioartificial Tracheal Transplant Feasible

THURSDAY, Nov. 24 (HealthDay News) -- A stem-cell-seeded bioartificial nanocomposite tracheobronchial scaffold can be used successfully to replace a complex airway defect, according to a proof-of-concept study published online Nov. 24 in The Lancet.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Recent Drop Seen in Oral, Pharyngeal Cancer Mortality

WEDNESDAY, Nov. 23 (HealthDay News) -- From 1993 to 2007, mortality rates decreased for black and white men and women with oral cavity and pharyngeal cancer, with a significant decline seen among those with more than 12 years of education, according to a study published in the November issue of the Archives of Otolaryngology -- Head & Neck Surgery.

Abstract
Full Text (subscription or payment may be required)

Ambulatory Systolic BP Tied to White Matter Hyperintensity

WEDNESDAY, Nov. 23 (HealthDay News) -- Among older individuals, ambulatory systolic blood pressure (BP), but not clinic BP, is associated with longitudinal progression of white matter hyperintensity (WMH) volume, according to a study published in the Nov. 22 issue of Circulation.

Abstract
Full Text (subscription or payment may be required)

Higher Coffee Consumption May Lower Endometrial Cancer Risk

TUESDAY, Nov. 22 (HealthDay News) -- Consumption of four or more cups of coffee per day is associated with a 25 percent reduced risk of endometrial cancer, according to a study published online Nov. 22 in Cancer Epidemiology, Biomarkers & Prevention.

Abstract
Full Text (subscription or payment may be required)

Similar Specific Survival for Unilateral, Bilateral Breast CA

TUESDAY, Nov. 22 (HealthDay News) -- The 10-year breast cancer-specific survival (BCSS) of patients with synchronous bilateral breast cancer (SBBC) and high-risk matches with unilateral breast cancer is not significantly different, according to a study published online Nov. 21 in the Journal of Clinical Oncology.

Abstract
Full Text (subscription or payment may be required)

Post-Mortem CT More Accurate Than MRI for Cause of Death

TUESDAY, Nov. 22 (HealthDay News) -- Post-mortem computed tomography (CT) is more accurate than magnetic resonance imaging (MRI) for providing a cause of death, according to a study published online Nov. 22 in The Lancet.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Plasma MicroRNA Panel ID'd for Diagnosing Hepatocellular Cancer

TUESDAY, Nov. 22 (HealthDay News) -- Hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) can be diagnosed with high accuracy using a microRNA panel, according to a study published online Nov. 21 in the Journal of Clinical Oncology.

Abstract
Full Text (subscription or payment may be required)
Editorial

Presence of Alzheimer's Biomarkers, Low BMI Linked

MONDAY, Nov. 21 (HealthDay News) -- Biomarkers of increased Alzheimer's disease (AD) burden, including Pittsburgh Compound B (PiB), β-amyloid peptide (Aβ), and total tau, are associated with lower body mass index (BMI) in individuals with mild cognitive impairment (MCI) or no dementia, according to a study published in the Nov. 22 issue of Neurology.

Abstract
Full Text (subscription or payment may be required)

Nonpunitive Method Improves Medical Error Reporting

MONDAY, Nov. 21 (HealthDay News) -- Medical error reporting in an academic pediatric ambulatory practice can be improved by a voluntary, nonpunitive, error-reporting system, according to a study published online Nov. 21 in Pediatrics.

Abstract
Full Text (subscription or payment may be required)

Grape Seed Extract Lowers Squamous Cell Carcinoma Risk

MONDAY, Nov. 21 (HealthDay News) -- Use of grape seed extract is associated with a reduced risk of cutaneous squamous cell carcinoma (SCC), according to a study published in the December issue of the Journal of the American Academy of Dermatology.

Abstract
Full Text (subscription or payment may be required)

Restrictive Policies Push Gene Influence on Smoking Behavior

MONDAY, Nov. 21 (HealthDay News) -- Compared to dizygotic twins, monozygotic twins are more likely to quit smoking during a similar time frame, and the influence of genetic factors was more pronounced in 1975 to 1980 than in 1960 to 1974, coincident with the implententation of restrictive smoking legislation, according to a study published in the November issue of Demography.

Abstract
Full Text (subscription or payment may be required)

Obese Mice Retain Insulin Sensitivity in Ovary/Pituitary

MONDAY, Nov. 21 (HealthDay News) -- In female mice with diet-induced obesity (DIO), insulin sensitivity is maintained in the pituitary and ovary, according to an experimental study published online Nov. 10 in Diabetes.

Abstract
Full Text (subscription or payment may be required)

Tyrosine Isoforms Involved in Concomitant Tumor Resistance

FRIDAY, Nov. 18 (HealthDay News) -- The ortho- and meta-isoforms of tyrosine are associated with concomitant tumor resistance (CR), according to an experimental study published in the Nov. 15 issue of Cancer Research.

Abstract
Full Text (subscription or payment may be required)

Long-Term Antiepileptic Drug Therapy Ups Atherosclerosis

FRIDAY, Nov. 18 (HealthDay News) -- For patients with epilepsy, long-term monotherapy with carbamazepine (CBZ), phenytoin (PHT), or valproic acid (VPA), but not lamotrigine (LTG), is associated with increased common carotid artery intima media thickness (CCA IMT) and altered circulatory markers of vascular risk, according to a study published online Nov. 15 in Epilepsia.

Abstract
Full Text (subscription or payment may be required)

Sleep Problem Severity Tied to Fibromyalgia Risk in Women

THURSDAY, Nov. 17 (HealthDay News) -- The severity of self-reported sleep problems in women has a significant dose-response association with their risk of developing fibromyalgia (FM) syndrome, with the association stronger among older and middle-aged women, according to a study published online Nov. 11 in Arthritis & Rheumatism.

Abstract
Full Text (subscription or payment may be required)

Twelve-Week Warfarin Dose Test Noninferior to Four-Week

TUESDAY, Nov. 15 (HealthDay News) -- Assessing warfarin dosing every 12 weeks is noninferior to assessment every four weeks, according to a study published in the Nov. 15 issue of the Annals of Internal Medicine.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Extended TNM Colon Cancer Staging Ups Prognostic Accuracy

TUESDAY, Nov. 15 (HealthDay News) -- The prognostic accuracy and sensitivity of the seventh edition American Joint Committee on Cancer's (AJCC's) tumor, node, metastasis (TNM) staging for colon cancer is improved by inclusion of routinely available demographic and pathologic data, according to a study published online Nov. 14 in the Journal of Clinical Oncology.

Abstract
Full Text (subscription or payment may be required)

Exposure to Specific Solvents Raises Parkinson's Risk

TUESDAY, Nov. 15 (HealthDay News) -- Exposure to certain solvents is associated with an increase in the risk of Parkinson's disease (PD), according to a study published online Nov. 14 in the Annals of Neurology.

Abstract
Full Text (subscription or payment may be required)

Researchers Develop Working Pituitary Gland in Mouse Model

MONDAY, Nov. 14 (HealthDay News) -- A functional pituitary gland can be produced from mouse embryonic stem cells, opening the door to possible new therapies for diseases of the pituitary gland, according to an experimental study published online Nov. 9 in Nature.

Abstract
Full Text (subscription or payment may be required)

Family History, Alcohol Tied to Benign Breast Disease Risk

MONDAY, Nov. 14 (HealthDay News) -- Consumption of seven alcoholic drinks per week during adolescence more than doubles the risk for benign breast disease (BBD) for those with a family history of breast cancer (BC) or BBD, according to a study published online Nov. 14 in Cancer.

Abstract
Full Text (subscription or payment may be required)

FDA Approves First Umbilical Cord Blood Product

FRIDAY, Nov. 11 (HealthDay News) -- The first product in the United States that uses human umbilical cord stem cells to treat disorders of the hematopoietic system has been approved by the U.S. Food and Drug Administration.

National Institutes of Health

Estimated Flu Incidence of 90 Million for 2008 in Under-5s

FRIDAY, Nov. 11 (HealthDay News) -- In 2008, there were an estimated 90 million new cases of influenza in children younger than 5 years of age, according to a review published online Nov. 11 in The Lancet.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Recurrent Pelvic Inflammation Ups Infertility, Pelvic Pain

FRIDAY, Nov. 11 (HealthDay News) -- Recurrent pelvic inflammatory disease (PID) is associated with a nearly two-fold increase in infertility and more than four-fold increase in chronic pelvic pain (CPP), according to a study published in the September issue of Sexually Transmitted Diseases.

Abstract
Full Text (subscription or payment may be required)

Adipotide Reduces White Adipose Tissue in Obese Monkeys

THURSDAY, Nov. 10 (HealthDay News) -- The ligand-directed peptidomimetic CKGGRAKDC-GG-D(KLAKLAK)2 (adipotide) reduces white adipose tissue in obese monkeys, according to an experimental study published in the Nov. 9 issue of Science Translational Medicine.

Abstract
Full Text (subscription or payment may be required)

Computer Prognostic Model Predicts Breast Cancer Survival

THURSDAY, Nov. 10 (HealthDay News) -- A computational system-based prognostic model incorporating breast cancer stromal and epithelial features can be used as a strong predictor of breast cancer survival, with stromal features more predictive of survival than epithelial ones, according to a study published in the Nov. 9 issue of Science Translational Medicine.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Epigenetic Therapy Shows Promise in Progressive NSCLC

THURSDAY, Nov. 10 (HealthDay News) -- Epigenetic therapy combined with low-dose azacitidine and entinostat is well-tolerated and provides an improvement in median survival similar to existing therapies for patients with metastatic non-small-cell lung cancer (NSCLC), according to a study published online Nov. 9 in Cancer Discovery.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Glove Use Linked to Reduced Hand Hygiene Compliance

THURSDAY, Nov. 10 (HealthDay News) -- Glove usage among healthcare workers is often inappropriate, and hand hygiene compliance is worse when gloves are worn, according to a study published online Oct. 17 in Infection Control and Hospital Epidemiology.

Abstract
Full Text (subscription or payment may be required)

Maternal DNA Analysis IDs Fetal Gene Microdeletions

WEDNESDAY, Nov. 9 (HealthDay News) -- Fetal chromosomal microdeletion can be identified by noninvasive analysis of maternal plasma DNA, according to a letter published in the Nov. 10 issue of the New England Journal of Medicine.

Full Text

Improved Breast CA Outcomes Affect Older Women Less

WEDNESDAY, Nov. 9 (HealthDay News) -- The impact of improvements in breast cancer outcomes has been less for women age 75 years or older than for women younger than 75, according to a study published online Nov. 7 in the Journal of Clinical Oncology.

Abstract
Full Text (subscription or payment may be required)
Editorial

Adjuvant Bevacizumab Feasible in Ovarian Cancer

WEDNESDAY, Nov. 9 (HealthDay News) -- Addition of bevacizumab to first-line intraperitoneal (IP) chemotherapy is feasible in ovarian cancer but increases the risk of bowel obstruction/perforation, according to a study published online Nov. 7 in the Journal of Clinical Oncology.

Abstract
Full Text (subscription or payment may be required)

HPV-16/18 Efficacious Against CIN3+, Adenocarcinoma in Situ

WEDNESDAY, Nov. 9 (HealthDay News) -- The human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine shows excellent efficacy against CIN3+ and adenocarcinoma in situ (AIS), and cross-protective efficacy against four oncogenic non-vaccine HPV types, according to two studies published online Nov. 9 in The Lancet Oncology.

Abstract - 1
Full Text (subscription or payment may be required)
Abstract - 2
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Poxviral Vaccine Benefits Some With Ovarian, Breast Cancer

TUESDAY, Nov. 8 (HealthDay News) -- Use of the recombinant poxviral vaccine (PANVAC) may be beneficial for some patients with metastatic breast and ovarian cancers with limited tumor burden and minimal exposure to chemotherapy, according to a study published online Nov. 8 in Clinical Cancer Research.

Abstract
Full Text (subscription or payment may be required)

Male Children With Autism Have More Prefrontal Neurons

TUESDAY, Nov. 8 (HealthDay News) -- Brain overgrowth in male children with autism involves an increase in the number of neurons in the prefrontal cortex (PFC), according to a study published in the Nov. 9 issue of the Journal of the American Medical Association.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

SNP in TBL1X ID'd As Candidate Gene for Male Autism

TUESDAY, Nov. 8 (HealthDay News) -- A genome-wide association study on the X-chromosome shows that a single nucleotide polymorphism (SNP), rs17321050, in the transducin β-like 1X-linked (TBL1X) gene is significantly linked to autism spectrum disorder (ASD) in males, according to a study published online Nov. 4 in Molecular Autism.

Abstract
Full Text

Centrally-Mediated Symptoms Tied to Pain Severity in OA

TUESDAY, Nov. 8 (HealthDay News) -- For women with osteoarthritis, age, radiographic severity, and centrally-mediated symptoms account for a considerable proportion of the variance of pain severity, according to a study published in the November issue of Arthritis Care & Research.

Abstract
Full Text (subscription or payment may be required)

Ridaforolimus Promising for Treating Advanced Sarcomas

TUESDAY, Nov. 8 (HealthDay News) -- Ridaforolimus treatment is associated with promising clinical benefit response (CBR) and progression-free survival (PFS) for patients with advanced sarcomas, according to a study published online Nov. 7 in the Journal of Clinical Oncology.

Abstract
Full Text (subscription or payment may be required)

Great Achievement at Young Age Function of Time, Not Field

MONDAY, Nov. 7 (HealthDay News) -- The frequency of great scientific achievements at young age is a function of time, and not related to the field, according to a study published online Nov. 7 in the Proceedings of the National Academy of Sciences.

Abstract
Full Text (subscription or payment may be required)

Novel Signaling Mechanism Mediates UV Phototransduction

MONDAY, Nov. 7 (HealthDay News) -- Immediate pigment darkening (IPD) may occur via a novel ultraviolet (UV) A signaling pathway involving calcium mobilization and early melanin synthesis in human epidermal melanocytes (HEMs), with the photopigment rhodopsin, which is expressed in HEMs, contributing to phototransduction, according to a study published online Nov. 3 in Current Biology.

Abstract
Full Text (subscription or payment may be required)

Lab Variables Predict Clinical Outcomes in Hepatitis C

MONDAY, Nov. 7 (HealthDay News) -- Clinical outcomes of patients with advanced hepatitis C can be predicted by models using baseline values of routine laboratory variables along with magnitude of change in their values over time, according to a study published in the November issue of Hepatology.

Abstract
Full Text (subscription or payment may be required)

Exercise Lowers CVD Death Risk Irrespective of Metabolic Factors

MONDAY, Nov. 7 (HealthDay News) -- Physical activity is associated with lower risk for cardiovascular disease (CVD) mortality, independent of metabolic risk factors, according to a study published in the Nov. 15 issue of The American Journal of Cardiology.

Abstract
Full Text (subscription or payment may be required)

Renin-Angiotensin Systems Tied to Obesity

FRIDAY, Nov. 4 (HealthDay News) -- Both the systemic and adipose tissue renin-angiotensin systems (RASs) are associated with obesity and insulin resistance, according to research published online Oct. 31 in Obesity Reviews.

Abstract
Full Text (subscription or payment may be required)

Statin Use in BAV Stenosis Tied to Ascending Aortic Size

FRIDAY, Nov. 4 (HealthDay News) -- Statin treatment in patients with bicuspid aortic valve (BAV) stenosis is associated with significantly lower ascending aortic size, according to a study published in the Nov. 15 issue of The American Journal of Cardiology.

Abstract
Full Text (subscription or payment may be required)

EGFR Level Predicts Survival Benefit of Cetuximab in NSCLC

FRIDAY, Nov. 4 (HealthDay News) -- For patients with advanced non-small-cell lung cancer (NSCLC), high epidermal growth factor receptor (EGFR) expression can predict the survival benefit for the addition of cetuximab to first-line chemotherapy, according to a study published online Nov. 4 in The Lancet Oncology.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Immune Response, Antibody Titers Seen Prior to Clinical RA

FRIDAY, Nov. 4 (HealthDay News) -- Anti-citrullinated protein antibody (ACPA) spreading starts several years prior to the onset of clinical rheumatoid arthritis (RA) with a marked increase in ACPA titers seen approximately two to four years before RA diagnosis, according to a study published in the November issue of Arthritis & Rheumatism.

Abstract
Full Text (subscription or payment may be required)

Rooms of Patients With A. baumannii Often Contaminated

FRIDAY, Nov. 4 (HealthDay News) -- A considerable proportion of rooms of patients colonized or infected with multidrug-resistant Acinetobacter baumannii (A. baumannii) (MDR-AB) have surfaces which are positive for A. baumannii, even in patients with a remote history of infection, according to a study published in the November issue of the American Journal of Infection Control.

Abstract
Full Text (subscription or payment may be required)

Major Progress Made in the Effort to Eradicate Polio in India

THURSDAY, Nov. 3 (HealthDay News) -- As of Oct. 31, only one case of wild poliovirus (WPV) was reported in India in 2011, compared with the 50,000 cases that were occurring each year when eradication initiatives were initiated in 1995. If this level of progress is sustained, India may be polio-free by 2012, according to research published in the Nov. 4 issue of the U.S. Centers for Disease Control and Prevention's Morbidity & Mortality Weekly Report.

Full Text

MelaFind Device Approved to Detect Melanoma

WEDNESDAY, Nov. 2 (HealthDay News) -- MelaFind -- a device that creates digital images of suspicious skin growths and compares them to a database of thousands of scans to analyze for signs of melanoma skin cancer -- has been approved by the U.S. Food and Drug Administration.

melanoma

Resveratrol Induces Metabolic Changes in Obese Humans

THURSDAY, Nov. 3 (HealthDay News) -- Thirty-day resveratrol supplementation in obese, but otherwise healthy, humans exerts favorable metabolic adaptations, according to a study published in the Nov. 2 issue of Cell Metabolism.

Abstract
Full Text

Graft Loss Higher With Kidneys Donated by Older Live Donors

THURSDAY, Nov. 3 (HealthDay News) -- For kidney recipients, graft loss is significantly higher when the live donor is age 70 years or older than when the live donor is aged 50 to 59 years, but is comparable to that from a deceased donor aged 50 to 59 years, according to a study published online Oct. 27 in the Clinical Journal of the American Society of Nephrology.

Abstract
Full Text (subscription or payment may be required)

No Concerning Patterns Seen With H1N1 Vaccine in Pregnancy

THURSDAY, Nov. 3 (HealthDay News) -- Administration of the influenza A (H1N1) vaccine to pregnant women seems to be safe and is not associated with an increase in adverse maternal or fetal outcomes, according to a study published in the November issue of the American Journal of Obstetrics & Gynecology.

Abstract
Full Text (subscription or payment may be required)

Senescent Cells ID'd As Cause of Age-Related Disorders

THURSDAY, Nov. 3 (HealthDay News) -- Senescent cells have a causal association with age-related phenotypes, and removal of senescent cells can prevent or delay tissue dysfunction and extend healthspan in mice with the BubR1 progeroid background, according to a letter published online Nov. 2 in Nature.

Abstract
Full Text (subscription or payment may be required)

Rectal CA Radiotherapy Tied to Lower Testosterone Levels

THURSDAY, Nov. 3 (HealthDay News) -- Men who are exposed to long-course radiotherapy for rectal cancer have significantly lower serum testosterone levels compared to pretreatment, according to a review published in the November issue of The Journal of Sexual Medicine.

Abstract
Full Text (subscription or payment may be required)

Risks for C. difficile Infection, Colonization Identified

THURSDAY, Nov. 3 (HealthDay News) -- Health care-associated Clostridium difficile (C. difficile) infection and colonization are differentially associated with defined host and pathogen variables, according to a study published in the Nov. 3 issue of the New England Journal of Medicine.

Full Text (subscription or payment may be required)

Caspase 9-Induced Apoptosis Shows Promise for Cell Therapy

WEDNESDAY, Nov. 2 (HealthDay News) -- Incorporation of inducible caspase 9 (iCasp9) into a transgene facilitates rapid induction of apoptosis of cells expressing the transgene with use of a dimerizing drug (AP1903), according to a study published in the Nov. 3 issue of the New England Journal of Medicine.

Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Physical Activity Reduces Link Between FTO and Obesity

WEDNESDAY, Nov. 2 (HealthDay News) -- The association of the FTO variant rs9939606 with obesity is attenuated in physically active compared to inactive adults, according to a meta-analysis published online Nov. 1 in PLoS Medicine.

Abstract
Full Text
Editorial

HPV Testing in Self-Collected Samples Has High Sensitivity

WEDNESDAY, Nov. 2 (HealthDay News) -- Human papillomavirus (HPV) DNA testing of self-collected vaginal specimens is more sensitive than clinic-based cervical cytology for detection of cervical cancer and cervical intraepithelial neoplasia (CIN) grade 2 or worse, but has lower positive predictive value, according to a study published online Nov. 3 in The Lancet.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

CDC: Opioid Overdoses Have Reached Epidemic Proportions

WEDNESDAY, Nov. 2 (HealthDay News) -- Opioid pain relievers (OPR) are involved in most drug overdose deaths; and OPR-related deaths, sales, and treatment admissions have increased in the last decade, according to a report published in the Nov. 1 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

Report

Basophil Status Doesn't Predict Immunotherapy Response

WEDNESDAY, Nov. 2 (HealthDay News) -- Peripheral blood basophil activation is not associated with efficacy of sublingual immunotherapy (SLIT) to grass pollen, nor is it predictive of adverse events or early onset of clinical responses, according to a study published in the December issue of Allergy.

Abstract
Full Text (subscription or payment may be required)

Low Levels of Alcohol During Adulthood Ups Breast Cancer Risk

TUESDAY, Nov. 1 (HealthDay News) -- Drinking low levels of alcohol during adult life is associated with a small but significant increase in breast cancer risk, according to a study published in the Nov. 2 issue of the Journal of the American Medical Association.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Over 30 Percent Survival With Allogeneic Cell Transplant

TUESDAY, Nov. 1 (HealthDay News) -- For older patients with advanced hematologic malignancies, treatment with minimally toxic nonmyeloablative allogeneic hematopoietic cell transplantation (HCT) is associated with five-year overall and progression-free survival of more than 30 percent, and age does not worsen outcomes, according to a study published in the Nov. 2 issue of the Journal of the American Medical Association.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Omental Adipocytes Play Key Role in Ovarian CA Metastasis

TUESDAY, Nov. 1 (HealthDay News) -- Primary human omental adipocytes promote homing, migration, and invasion of ovarian cancer cells to the omentum, and fatty-acid binding protein 4 (FABP4) seems to have a role in metastatic ovarian tumor growth, according to a letter published online Oct. 30 in Nature Medicine.

Abstract
Full Text (subscription or payment may be required)

Copyright © 2011 ScoutNews, LLC. All rights reserved.


Previous: November 2011 Briefing - Nephrology Next: November 2011 Briefing - Radiology

Reader comments on this article are listed below. Review our comments policy.


Submit your opinion:

Name:

Email:

Location:

URL:

Remember my personal information

Notify me of follow-up comments?

advertisement.gif (61x7 -- 0 bytes)
 

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

Doctors Lounge Membership Application

 
     

 advertisement.gif (61x7 -- 0 bytes)

 

 

Useful Sites
MediLexicon
  Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us
Copyright © 2001-2014
Doctors Lounge.
All rights reserved.

Medical Reference:
Diseases | Symptoms
Drugs | Labs | Procedures
Software | Tutorials

Advertising
Links | Humor
Forum Archive
CME | Conferences

Privacy Statement
Terms & Conditions
Editorial Board
About us | Email

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.