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Category: Geriatrics | Monthly Briefing

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November 2011 Briefing - Geriatrics

Last Updated: December 01, 2011.

 

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Here are what the editors at HealthDay consider to be the most important developments in Geriatrics for November 2011. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

PiB-/FDG-PET Helpful in Differentiation of Dementia

WEDNESDAY, Nov. 30 (HealthDay News) -- Photon emission tomography (PET) with amyloid ligand Pittsburgh compound B (PiB-PET) has similar accuracy as PET with fluorodeoxyglucose (FDG-PET) for differentiating Alzheimer's disease (AD) from frontotemporal lobar degeneration (FTLD), according to a study published online Nov. 30 in Neurology.

Abstract
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U.S. Patients Highly Satisfied With Outpatient Medical Care

WEDNESDAY, Nov. 30 (HealthDay News) -- Patients in the United States are, in general, highly satisfied with their outpatient medical care, according to a study published online Oct. 3 in Health Outcomes Research in Medicine.

Abstract
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Objective Physical Activity Impacts Sleep Variables

WEDNESDAY, Nov. 30 (HealthDay News) -- Objectively-measured physical activity is significantly associated with sleep-related parameters in adults of all ages, according to a study published in the December issue of Mental Health and Physical Activity.

Abstract
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Long-Term Superiority Seen in Group Intervention for Neck Pain

WEDNESDAY, Nov. 30 (HealthDay News) -- For patients with persistent tension-type neck pain, a multi-component pain and stress self-management group intervention (PASS) is superior to individually-administered physical therapy (IAPT) at two years, according to a study published in the Dec. 1 issue of Spine.

Abstract
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Opioid Rx for Chronic Abdominal Pain Up Over Last Decade

TUESDAY, Nov. 29 (HealthDay News) -- The prevalence of opioid prescriptions for chronic abdominal pain more than doubled between 1997 and 2008 in the United States, with prescriptions most common for patients aged 25 to 40 years, according to a study published in the December issue of Clinical Gastroenterology and Hepatology.

Abstract
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Prediagnosis BMI Predicts Mortality in Patients With CRC

TUESDAY, Nov. 29 (HealthDay News) -- For patients with nonmetastatic colorectal cancer (CRC), prediagnosis, but not postdiagnosis, body mass index (BMI) is an important predictor of all-cause and cause-specific mortality; and patients with type 2 diabetes mellitus (T2DM) have a higher risk of mortality, according to two studies published online Nov. 28 in the Journal of Clinical Oncology.

Abstract - Campbell
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Abstract - Dehal
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Editorial

NSAID, Statin Use Cuts Cancer Risk in Barrett's Esophagus

TUESDAY, Nov. 29 (HealthDay News) -- For patients with Barrett's esophagus, use of nonsteroidal anti-inflammatory drugs (NSAIDs) and statins reduces the risk of neoplastic progression, with combined use giving additional protection, according to a study published in the December issue of Gastroenterology.

Abstract
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High-Performing Docs Learn Equally From Success, Failure

MONDAY, Nov. 28 (HealthDay News) -- Among physicians making decisions in a medically-framed learning task, high and low performers show distinct behavioral and neural patterns of learning, according to a study published online Nov. 23 in PLoS One.

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Small Cell Carcinoma of Urinary Bladder Incidence Up

MONDAY, Nov. 28 (HealthDay News) -- The incidence of small cell carcinoma of the urinary bladder (SCCB) increased from 1991 to 2005, with elderly Caucasian men being the most commonly affected, according to a study published in the Dec. 1 issue of Cancer.

Abstract
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Nearly One in 10 Patients With PCI Readmits Within 30 Days

MONDAY, Nov. 28 (HealthDay News) -- About one in 10 patients undergoing percutaneous coronary intervention (PCI) are readmitted within 30 days; and 30-day readmission is associated with an increased risk of one-year mortality, according to a study published online Nov. 28 in the Archives of Internal Medicine.

Abstract
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Autoimmune Disorders Tied to Pulmonary Embolism Risk

MONDAY, Nov. 28 (HealthDay News) -- Autoimmune disorders are associated with an increased risk of pulmonary embolism, particularly during the first year after hospitalization, according to a study published online Nov. 26 in The Lancet.

Abstract
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Default-Mode Brain Network Deactivation Seen in Meditators

THURSDAY, Nov. 24 (HealthDay News) -- Experienced meditators have relative deactivation of the main modes of the default mode network (DMN), and stronger coupling between the posterior cingulate, dorsal anterior cingulate, and dorsolateral prefrontal cortices, according to a study published online Nov. 23 in the Proceedings of the National Academy of Sciences.

Abstract
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Dabigatran Poses Challenge in Treating Injured Patients

WEDNESDAY, Nov. 23 (HealthDay News) -- Dabigatran etexilate, a new oral direct thrombin inhibitor, should be used with caution due to a lack of readily available methods to assess the degree of anticoagulation or reverse its effects, posing a threat of fatal bleeding complications for injured patients, according to a letter published in the Nov. 24 issue of the New England Journal of Medicine.

Letter

Drugs ID'd in Most Older Adult Emergency Hospitalizations

WEDNESDAY, Nov. 23 (HealthDay News) -- Adverse drug events from commonly used medications, including warfarin, insulin, oral antiplatelet agents, and oral hypoglycemic agents, account for the majority of emergency hospitalizations in older adults in the United States, according to a study published in the Nov. 24 issue of the New England Journal of Medicine.

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Long-Term Survival Factors ID'd for Head, Neck Cancer

WEDNESDAY, Nov. 23 (HealthDay News) -- Older age, advanced stage, pain, poor quality of life, and smoking are risk factors associated with poorer survival among two-year survivors of head and neck cancer, according to a study published in the November issue of the Archives of Otolaryngology -- Head & Neck Surgery.

Abstract
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Ambulatory Systolic BP Tied to White Matter Hyperintensity

WEDNESDAY, Nov. 23 (HealthDay News) -- Among older individuals, ambulatory systolic blood pressure (BP), but not clinic BP, is associated with longitudinal progression of white matter hyperintensity (WMH) volume, according to a study published in the Nov. 22 issue of Circulation.

Abstract
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Urinary Potassium, Sodium Excretion Tied to CV Events

TUESDAY, Nov. 22 (HealthDay News) -- Estimated urinary sodium and potassium excretion are associated with cardiovascular (CV) events, according to a study published in the Nov. 23/30 issue of the Journal of the American Medical Association.

Abstract
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Editorial (subscription or payment may be required)

Decision Aids Help Caregivers Discuss Terminal Illness

TUESDAY, Nov. 22 (HealthDay News) -- A decision aid, consisting of a video and an accompanying workbook, can help family caregivers discuss terminal disease status with a family member with cancer, according to a study published online Nov. 21 in the Journal of Clinical Oncology.

Abstract
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BMI Predicts 30-Day Post-Surgery Mortality Risk

TUESDAY, Nov. 22 (HealthDay News) -- Body mass index (BMI) is a significant predictor of 30-day mortality after surgical procedures, irrespective of the type of surgery, according to a study published online Nov. 21 in the Archives of Surgery.

Abstract
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Black Patients Have Worse Diverticulitis Surgery Outcomes

TUESDAY, Nov. 22 (HealthDay News) -- Black patients who undergo surgery for diverticulitis have a higher risk of undergoing emergency procedures, and an increased mortality risk than white patients, according to a study published in the November issue of the Archives of Surgery.

Abstract
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Post-Mortem CT More Accurate Than MRI for Cause of Death

TUESDAY, Nov. 22 (HealthDay News) -- Post-mortem computed tomography (CT) is more accurate than magnetic resonance imaging (MRI) for providing a cause of death, according to a study published online Nov. 22 in The Lancet.

Abstract
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Presence of Alzheimer's Biomarkers, Low BMI Linked

MONDAY, Nov. 21 (HealthDay News) -- Biomarkers of increased Alzheimer's disease (AD) burden, including Pittsburgh Compound B (PiB), β-amyloid peptide (Aβ), and total tau, are associated with lower body mass index (BMI) in individuals with mild cognitive impairment (MCI) or no dementia, according to a study published in the Nov. 22 issue of Neurology.

Abstract
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NIH: The 90-Plus Population Is on the Rise in the U.S.

MONDAY, Nov. 21 (HealthDay News) -- The U.S. population aged 90 years and older (90-plus) is increasing and has distinct characteristics, according to a report by the U.S. Census Bureau, commissioned by the National Institute on Aging at the National Institutes of Health.

Report

Nonpunitive Method Improves Medical Error Reporting

MONDAY, Nov. 21 (HealthDay News) -- Medical error reporting in an academic pediatric ambulatory practice can be improved by a voluntary, nonpunitive, error-reporting system, according to a study published online Nov. 21 in Pediatrics.

Abstract
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Factors Impacting Assignment to Triage Risk Level 2/3 ID'd

FRIDAY, Nov. 18 (HealthDay News) -- A triage nurse's decision to assign a patient to risk level 2 or 3 of the Emergency Severity Index (ESI) triage system is influenced by specific factors, according to a study published in the November issue of the Journal of Emergency Nursing.

Abstract
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Rapid Safety Monitoring of H1N1 Vaccine Feasible

FRIDAY, Nov. 18 (HealthDay News) -- A rapid safety surveillance system using modern technology is feasible for monitoring new H1N1 vaccines given or offered to large numbers of patients under normal conditions within a short period of time, according to a study published online Nov. 15 in the British Journal of Clinical Pharmacology.

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Lower Floor Stiffness Reduces Peak Spine Forces in Falls

THURSDAY, Nov. 17 (HealthDay News) -- Peak spine force in backward falls is affected by the floor stiffness, according to a study published online Nov. 8 in Spine.

Abstract
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Sleep Problem Severity Tied to Fibromyalgia Risk in Women

THURSDAY, Nov. 17 (HealthDay News) -- The severity of self-reported sleep problems in women has a significant dose-response association with their risk of developing fibromyalgia (FM) syndrome, with the association stronger among older and middle-aged women, according to a study published online Nov. 11 in Arthritis & Rheumatism.

Abstract
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Retinal Changes Tied to Impaired Daily Living Activities

THURSDAY, Nov. 17 (HealthDay News) -- The presence of two or more retinal microvascular changes in community-dwelling older adults is associated with increased disability in performance of activities of daily living (ADL), according to a study published online Nov. 14 in the Archives of Ophthalmology.

Abstract
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AHA Policy Statement on Cardiac Rehabilitation Issued

THURSDAY, Nov. 17 (HealthDay News) -- For patients with cardiovascular disease, participation in cardiac rehabilitation/secondary prevention programs (CR/SPPs) can be enhanced by overcoming patient and health care system-related barriers, and implementing new methods and policies for referral and enrollment, according to an American Heart Association policy statement published online Nov. 14 in Circulation.

Report

Breast Cancer Survivors Have Impaired Neurological Function

WEDNESDAY, Nov. 16 (HealthDay News) -- Breast cancer (BC) survivors have significantly reduced activation of the prefrontal cortex, with additional reductions in prefrontal function and poorer executive functioning for women treated with chemotherapy, according to a study published in the November issue of the Archives of Neurology.

Abstract
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U.S. Oncologists Rate Selves Highly in Pain Management

TUESDAY, Nov. 15 (HealthDay News) -- Although U.S oncologists rate their specialty highly in terms of pain management, they acknowledge treatment barriers to optimal care, and consider their training to be poor, according to a study published online Nov. 14 in the Journal of Clinical Oncology.

Abstract
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Editorial

Exposure to Specific Solvents Raises Parkinson's Risk

TUESDAY, Nov. 15 (HealthDay News) -- Exposure to certain solvents is associated with an increase in the risk of Parkinson's disease (PD), according to a study published online Nov. 14 in the Annals of Neurology.

Abstract
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Patients Without Insurance Have Shorter Hospital Stays

TUESDAY, Nov. 15 (HealthDay News) -- Patients without Medicaid or any other insurance, with ambulatory care-sensitive conditions (ACSCs) or non-ACSCs, have shorter lengths of stay in hospitals than patients with insurance, according to a study published in the November/December issue of the Annals of Family Medicine.

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Twelve-Week Warfarin Dose Test Noninferior to Four-Week

TUESDAY, Nov. 15 (HealthDay News) -- Assessing warfarin dosing every 12 weeks is noninferior to assessment every four weeks, according to a study published in the Nov. 15 issue of the Annals of Internal Medicine.

Abstract
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Editorial (subscription or payment may be required)

Transient Ischemic Attack Reduces Life Expectancy

FRIDAY, Nov. 11 (HealthDay News) -- Transient ischemic attack (TIA) reduces life expectancy, particularly in patients older than 65 years or with a previous history of stroke and heart problems, according to a study published online Nov. 10 in Stroke.

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Half of U.S. Adult Smokers Tried to Quit Last Year

THURSDAY, Nov. 10 (HealthDay News) -- The majority of adults who smoke would like to quit, but only about a third of them seek medical help and/or support to do so, according to research published in the Nov. 11 issue of the U.S. Centers for Disease Control and Prevention's Morbidity & Mortality Weekly Report.

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Overactive Bladder Prevalent in Patients With Diabetes

THURSDAY, Nov. 10 (HealthDay News) -- Overactive bladder (OAB) is prevalent in patients with type 2 diabetes, with the prevalence higher in older patients and those with long-standing diabetes, according to a study published in the November issue of Urology.

Abstract
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Zostavax Still Recommended Only for Those 60 and Over

THURSDAY, Nov. 10 (HealthDay News) -- Despite the U.S. Food and Drug Administration's expansion of the indication for herpes zoster vaccination to include a younger cohort, the Advisory Committee on Immunization Practices (ACIP) still recommends the vaccine only for adults 60 and older, according to a report published in the Nov. 9 issue of the U.S. Centers for Disease Control and Prevention's Morbidity & Mortality Weekly Report.

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Efficacy of Balance Exercises in the Elderly Questioned

THURSDAY, Nov. 10 (HealthDay News) -- Some exercise types may be effective for improving balance in older people, although the evidence is weak, according to a review published online Nov. 9 in the Cochrane Database of Systematic Reviews.

Abstract
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Bedside EEG Detects Awareness in Vegetative Patients

THURSDAY, Nov. 10 (HealthDay News) -- Electroencephalography (EEG) performed at the bedside of patients in a vegetative state can detect residual cognitive function and conscious awareness, according to a study published online Nov. 10 in The Lancet.

Abstract
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Glove Use Linked to Reduced Hand Hygiene Compliance

THURSDAY, Nov. 10 (HealthDay News) -- Glove usage among healthcare workers is often inappropriate, and hand hygiene compliance is worse when gloves are worn, according to a study published online Oct. 17 in Infection Control and Hospital Epidemiology.

Abstract
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Evidence Shows Reduced Sodium Intake Lowers BP

THURSDAY, Nov. 10 (HealthDay News) -- Reduced sodium intake is associated with a significant decrease in blood pressure (BP), and a concomitant increase in plasma levels of renin, aldosterone, adrenaline, noradrenaline, cholesterol, and triglycerides, according to a review published online Nov. 9 in the American Journal of Hypertension.

Abstract
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Leg Motor Restlessness More Common in Parkinson's

THURSDAY, Nov. 10 (HealthDay News) -- Patients with early, unmedicated Parkinson's disease (PD) have a significantly increased risk for leg motor restlessness (LMR), but not restless legs syndrome (RLS), according to a study published online Nov. 9 in Neurology.

Abstract
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Trilipix Not Found to Reduce Risk of Coronary Events

WEDNESDAY, Nov. 9 (HealthDay News) -- Trilipix (fenofibric acid), a cholesterol-lowering medication, may not reduce the risk of heart attack or stroke, and physicians should consider the risks and benefits of the drug before prescribing it to patients, according to a safety communication issued Nov. 9 by the U.S. Food and Drug Administration.

More Information

Improved Breast CA Outcomes Affect Older Women Less

WEDNESDAY, Nov. 9 (HealthDay News) -- The impact of improvements in breast cancer outcomes has been less for women age 75 years or older than for women younger than 75, according to a study published online Nov. 7 in the Journal of Clinical Oncology.

Abstract
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Editorial

No Added Benefits of Cranial Bypass in Stroke Prevention

TUESDAY, Nov. 8 (HealthDay News) -- Extracranial-intracranial (EC-IC) bypass surgery in addition to medical therapy offers no additional benefit over medical therapy alone in preventing recurrent stroke in recent symptomatic atherosclerotic internal carotid artery occlusion (AICAO), according to a study published in the Nov. 9 issue of the Journal of the American Medical Association.

Abstract
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Centrally-Mediated Symptoms Tied to Pain Severity in OA

TUESDAY, Nov. 8 (HealthDay News) -- For women with osteoarthritis, age, radiographic severity, and centrally-mediated symptoms account for a considerable proportion of the variance of pain severity, according to a study published in the November issue of Arthritis Care & Research.

Abstract
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Great Achievement at Young Age Function of Time, Not Field

MONDAY, Nov. 7 (HealthDay News) -- The frequency of great scientific achievements at young age is a function of time, and not related to the field, according to a study published online Nov. 7 in the Proceedings of the National Academy of Sciences.

Abstract
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Impact of Exercise Lessened by Metformin in Prediabetes

MONDAY, Nov. 7 (HealthDay News) -- For men and women with prediabetes, insulin sensitivity increases to a similar extent with exercise training, metformin, or a combination of the two, with metformin impacting slightly on the effect of exercise, according to a study published online Oct. 31 in Diabetes Care.

Abstract
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Gender Difference in Failure Patterns for Hip Resurfacing

MONDAY, Nov. 7 (HealthDay News) -- Gender differences exist in the failure patterns of metal-on-metal hip resurfacing arthroplasty, according to a study published online Oct. 13 in BMC Medicine.

Abstract
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Exercise Lowers CVD Death Risk Irrespective of Metabolic Factors

MONDAY, Nov. 7 (HealthDay News) -- Physical activity is associated with lower risk for cardiovascular disease (CVD) mortality, independent of metabolic risk factors, according to a study published in the Nov. 15 issue of The American Journal of Cardiology.

Abstract
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Renin-Angiotensin Systems Tied to Obesity

FRIDAY, Nov. 4 (HealthDay News) -- Both the systemic and adipose tissue renin-angiotensin systems (RASs) are associated with obesity and insulin resistance, according to research published online Oct. 31 in Obesity Reviews.

Abstract
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Receptionists Contribute to Safety of Repeat Prescriptions

FRIDAY, Nov. 4 (HealthDay News) -- Receptionists and administrative staff of general practices in the United Kingdom make important contributions to quality and safety in repeat prescribing, which are often unknown to clinicians, according to a study published online Nov. 3 in BMJ.

Abstract
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Adoption of English Diet Could Reduce U.K. Mortality

FRIDAY, Nov. 4 (HealthDay News) -- Following a diet with nutritional quality equivalent to the English diet would substantially reduce mortality in Wales, Scotland, and Northern Ireland, according to a study published online Nov. 2 in BMJ Open.

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Rooms of Patients With A. baumannii Often Contaminated

FRIDAY, Nov. 4 (HealthDay News) -- A considerable proportion of rooms of patients colonized or infected with multidrug-resistant Acinetobacter baumannii (A. baumannii) (MDR-AB) have surfaces which are positive for A. baumannii, even in patients with a remote history of infection, according to a study published in the November issue of the American Journal of Infection Control.

Abstract
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Carisoprodol-Related Emergency Visits Up in United States

THURSDAY, Nov. 3 (HealthDay News) -- Carisoprodol misuse- or abuse-related emergency department visits increased in the United States between 2004 and 2009, with the majority of visits involving other pharmaceuticals, according to a report published online Nov. 3 by the Substance Abuse and Mental Health Services Administration (SAMHSA).

Report

Device Approved to Repair Abdominal Aneurysms

WEDNESDAY, Nov. 2 (HealthDay News) -- A device that helps repair abdominal aneurysms in people with small arteries has been approved by the U.S. Food and Drug Administration.

this approval

No Medicare Savings From Disease-Management Hotline

THURSDAY, Nov. 3 (HealthDay News) -- Commercial disease-management companies using nurse-based call centers modestly improve quality-of-care measures in Medicare fee-for-service programs with no evident reduction in costs of care or acute care utilization, according to a study published in the Nov. 3 issue of the New England Journal of Medicine.

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Risks for C. difficile Infection, Colonization Identified

THURSDAY, Nov. 3 (HealthDay News) -- Health care-associated Clostridium difficile (C. difficile) infection and colonization are differentially associated with defined host and pathogen variables, according to a study published in the Nov. 3 issue of the New England Journal of Medicine.

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Graft Loss Higher With Kidneys Donated by Older Live Donors

THURSDAY, Nov. 3 (HealthDay News) -- For kidney recipients, graft loss is significantly higher when the live donor is age 70 years or older than when the live donor is aged 50 to 59 years, but is comparable to that from a deceased donor aged 50 to 59 years, according to a study published online Oct. 27 in the Clinical Journal of the American Society of Nephrology.

Abstract
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Rectal CA Radiotherapy Tied to Lower Testosterone Levels

THURSDAY, Nov. 3 (HealthDay News) -- Men who are exposed to long-course radiotherapy for rectal cancer have significantly lower serum testosterone levels compared to pretreatment, according to a review published in the November issue of The Journal of Sexual Medicine.

Abstract
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Senescent Cells ID'd As Cause of Age-Related Disorders

THURSDAY, Nov. 3 (HealthDay News) -- Senescent cells have a causal association with age-related phenotypes, and removal of senescent cells can prevent or delay tissue dysfunction and extend healthspan in mice with the BubR1 progeroid background, according to a letter published online Nov. 2 in Nature.

Abstract
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CDC: Opioid Overdoses Have Reached Epidemic Proportions

WEDNESDAY, Nov. 2 (HealthDay News) -- Opioid pain relievers (OPR) are involved in most drug overdose deaths; and OPR-related deaths, sales, and treatment admissions have increased in the last decade, according to a report published in the Nov. 1 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

Report

Over 30 Percent Survival With Allogeneic Cell Transplant

TUESDAY, Nov. 1 (HealthDay News) -- For older patients with advanced hematologic malignancies, treatment with minimally toxic nonmyeloablative allogeneic hematopoietic cell transplantation (HCT) is associated with five-year overall and progression-free survival of more than 30 percent, and age does not worsen outcomes, according to a study published in the Nov. 2 issue of the Journal of the American Medical Association.

Abstract
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Sex Steroid Levels Tied to Body Composition in Older Men

TUESDAY, Nov. 1 (HealthDay News) -- Higher levels of testosterone are associated with reduced loss of appendicular lean mass in older men, especially those who are losing weight, according to a study published online Oct. 5 in the Journal of Clinical Endocrinology & Metabolism.

Abstract
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Loneliness Significantly Linked to Sleep Fragmentation

TUESDAY, Nov. 1 (HealthDay News) -- Loneliness is significantly associated with sleep fragmentation, but not sleep duration or subjective sleep measures, according to a study published in the Nov. 1 issue of SLEEP.

Abstract
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Hand-Held Metal Detectors Safe With Implanted Devices

TUESDAY, Nov. 1 (HealthDay News) -- Exposure to hand-held metal detectors does not affect the function of pacemakers or implantable cardioverter defibrillators (ICDs), according to a study published in the Nov. 1 issue of Annals of Internal Medicine.

Abstract
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