Create Account | Sign In: Author or Forum

 
News  |  Journals  |  Conferences  |  Opinion  |  Articles  |  Forums  |  Twitter    
 
Category: Cardiology | Family Medicine | Geriatrics | Internal Medicine | Critical Care | Emergency Medicine | Nursing | Radiology | Journal

Back to Journal Articles

Coronary MRI Good Alternative to SPECT for CHD Diagnosis

Last Updated: December 26, 2011.

 

Cardiovascular MR has better sensitivity, negative predictive value than single-photon emission CT

Share |

Comments: (0)

Tell-a-Friend

 

  Related
 
For patients with suspected coronary heart disease, a multiparametric cardiovascular magnetic resonance protocol has better sensitivity and negative predictive value, and similar specificity as single-photon emission computed tomography, according to a study published online Dec. 23 in The Lancet.

MONDAY, Dec. 26 (HealthDay News) -- For patients with suspected coronary heart disease, a multiparametric cardiovascular magnetic resonance (CMR) protocol has better sensitivity and negative predictive value, and similar specificity as single-photon emission computed tomography (SPECT), according to a study published online Dec. 23 in The Lancet.

John P. Greenwood, Ph.D., from the Multidisciplinary Cardiovascular Research Centre in Leeds, U.K., and colleagues evaluated the diagnostic accuracy of a multiparametric CMR protocol, and compared CMR with SPECT in patients with suspected angina pectoris and at least one cardiovascular risk factor. CMR, SPECT, and invasive X-ray coronary angiography were performed on 752 participants. Cine imaging, rest and adenosine stress perfusion, late gadolinium enhancement, and MR coronary angiography comprised the CMR protocol. CMR diagnostic accuracy, based on X-ray coronary angiography as the reference standard, was the primary outcome measured.

The investigators found that X-ray angiography identified significant CHD in 39 percent of the participants. The sensitivity, specificity, positive predictive, and negative predictive values of multiparametric CMR were 86.5, 83.4, 77.2, and 90.5 percent, respectively. The sensitivity, specificity, positive predictive, and negative predictive values of SPECT were 66.5, 82.6, 71.4, and 79.1 percent, respectively. There were significant differences between CMR and SPECT sensitivities and negative predictive values, but not significant differences for specificities and positive predictive values.

"This trial has shown that, in a large population with suspected angina pectoris, CMR is an alternative to SPECT for the detection of clinically significant coronary heart disease, with better sensitivity and negative predictive values," the authors write.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Copyright © 2011 HealthDay. All rights reserved.


Previous: Study Compares Onset of Action of Two Types of Botulinum Toxin Next: U.S. Spends Up to $34.4 Billion Annually on Uterine Fibroids

Reader comments on this article are listed below. Review our comments policy.


Submit your opinion:

Name:

Email:

Location:

URL:

Remember my personal information

Notify me of follow-up comments?

advertisement.gif (61x7 -- 0 bytes)
 

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

Doctors Lounge Membership Application

 
     

 advertisement.gif (61x7 -- 0 bytes)

 

 

Useful Sites
MediLexicon
  Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us
Copyright © 2001-2014
Doctors Lounge.
All rights reserved.

Medical Reference:
Diseases | Symptoms
Drugs | Labs | Procedures
Software | Tutorials

Advertising
Links | Humor
Forum Archive
CME | Conferences

Privacy Statement
Terms & Conditions
Editorial Board
About us | Email

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.