January 2012 Briefing - AllergyLast Updated: February 01, 2012.
Here are what the editors at HealthDay consider to be the most important developments in Allergy for January 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Anaphylactic Shock After Immunizations Is Rare
THURSDAY, Jan. 26 (HealthDay News) -- Anaphylactic shock following immunization is extremely rare in children, and in the few reported cases, some children have a delayed onset of symptoms, according to a study published online Jan. 23 in the Archives of Disease in Childhood.
Overuse of Health Care Services Understudied
WEDNESDAY, Jan. 25 (HealthDay News) -- Overuse of health care services in the United States is an understudied problem, with the majority of research limited to a few interventions, according to a review published in the Jan. 23 issue of the Archives of Internal Medicine.
Unemployed Have Poorer Mental and Physical Health
TUESDAY, Jan. 24 (HealthDay News) -- Unemployed adults are about half as likely to have health insurance as employed individuals; have poorer mental and physical health, regardless of their insurance status; and are less likely to receive needed medical care and prescriptions, according to a January data brief issued by the National Center for Health Statistics.
Lansoprazole Does Not Improve Asthma Control in Children
TUESDAY, Jan. 24 (HealthDay News) -- For children with asthma without overt gastroesophageal reflux (GER), treatment with the proton pump inhibitor (PPI) lansoprazole is not associated with improved asthma control, according to a study published in the Jan. 25 issue of the Journal of the American Medical Association.
Fetal Growth Not Linked to Childhood Asthma
TUESDAY, Jan. 24 (HealthDay News) -- Fetal growth restriction or acceleration is not associated with asthma symptoms in childhood, according to a study published online Jan. 20 in the American Journal of Respiratory and Critical Care Medicine.
Negative Social Interactions Linked to Inflammation
TUESDAY, Jan. 24 (HealthDay News) -- Everyday social interactions that are negative or competitive are associated with elevated levels of inflammatory cytokines, according to a study published online Jan. 23 in the Proceedings of the National Academy of Sciences.
Mild-to-Moderate Asthma Frequently Non-Eosinophilic
MONDAY, Jan. 23 (HealthDay News) -- Approximately half of all patients with mild-to-moderate asthma are persistently non-eosinophilic, according to a study published online Jan. 20 in the American Journal of Respiratory and Critical Care Medicine.
Positive Patch Test Reaction Rates Similar for Elderly, Adults
FRIDAY, Jan. 20 (HealthDay News) -- Approximately two-thirds of older individuals have at least one positive patch test reaction to contact allergens, similar to the rates for adults and significantly increased compared with the rates for children, according to a study published in the February issue of the Journal of the American Academy of Dermatology.
Osteoporotic Fracture Risk High in Systemic Mastocytosis
THURSDAY, Jan. 19 (HealthDay News) -- There is a high risk of osteoporotic fractures and osteoporosis in patients with indolent systemic mastocytosis (ISM), according to a study published online Jan. 9 in Allergy.
Airway Smooth Muscle Layer Has Key Role in Asthma
TUESDAY, Jan. 17 (HealthDay News) -- Although extracellular matrix (ECM) expression in the airway smooth muscle (ASM) layer is not different for patients with asthma and controls, it is associated with the dynamics of airway function in patients with asthma, according to a study published online Jan. 9 in Allergy.
Maternal Asthma Meds Not Linked to Most Birth Defects
MONDAY, Jan. 16 (HealthDay News) -- Use of asthma medications in early pregnancy is not associated with most birth defects, but positive associations are present for a few specific defects, including isolated esophageal and anorectal atresia and omphalocele, according to a study published online Jan. 16 in Pediatrics.
U.S. Health Care Expenditure Still Unevenly Distributed
FRIDAY, Jan. 13 (HealthDay News) -- Health care expenditure in the United States is still unevenly distributed, with 1 percent of the population accounting for approximately 20 percent of expenditure in 2008 and 2009, according to a January statistical brief published by the Agency for Healthcare Research and Quality (AHRQ).
Gene Variant Identified in Families With Cold Urticaria
THURSDAY, Jan. 12 (HealthDay News) -- The PLCG2 gene, which encodes phospholipase Cγ2, has been found to be associated with a dominantly inherited medical condition causing cold urticaria, immunodeficiency, and autoimmunity, according to a study published online Jan. 11 in the New England Journal of Medicine.
Montelukast Doesn't Cut Upper Respiratory Infection Incidence
WEDNESDAY, Jan. 4 (HealthDay News) -- For young children, 12-week prophylactic treatment with montelukast does not reduce the incidence of upper respiratory tract infections (URIs), according to a study published online Jan. 4 in Pediatrics.