Here are what the editors at HealthDay consider to be the most important developments in Rheumatology for February 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Inactivity and Obesity Relate to Cognitive Impairment in Lupus
WEDNESDAY, Feb. 29 (HealthDay News) -- Physical inactivity and obesity are associated with impaired cognitive function, especially executive functions, in women with systemic lupus erythematosus (SLE), according to research published online Feb. 15 in Arthritis Care & Research.
Low Back Pain Counseling Strategy Ups Return to Work
MONDAY, Feb. 27 (HealthDay News) -- Combining a disability evaluation with proactive counseling for workers with low back pain (LBP) results in a higher return-to-work rate, which is statistically significant at one year, according to a study published online Feb. 16 in Spine.
Bisphosphonate Use Linked to Reduced Colorectal Cancer Risk
THURSDAY, Feb. 23 (HealthDay News) -- Exposure to bisphosphonates (BPs) is associated with a reduction in the risk of colorectal cancer (CRC), a reduction that is significant only for risedronic acid, according to a study published in the March 1 issue of Cancer.
Classification-Based Therapy No Better for Back Pain
MONDAY, Feb. 20 (HealthDay News) -- Treatment of patients with lower back pain (LBP) using a classification-based physical therapy approach shows no statistically significant superiority to treatment with usual physical therapy care, according to a study published online Feb. 13 in Spine.
Women With RA, Lupus Have Fewer Children Than Planned
FRIDAY, Feb. 17 (HealthDay News) -- More than half of young women diagnosed with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) have fewer children than they had hoped for, according to a study published online Feb. 16 in Arthritis Care & Research.
New Data Published on Safety of Leflunomide in Pregnancy
WEDNESDAY, Feb. 15 (HealthDay News) -- New data on birth outcomes provide some reassurance to women who are inadvertently exposed to leflunomide before or during pregnancy, according to research published online Feb. 3 in Arthritis & Rheumatism.
Anti-apoA-1 Ups Cardiovascular Risk Prediction in RA
WEDNESDAY, Feb. 15 (HealthDay News) -- Adding the biomarker anti-apolipoprotein A-1 IgG (anti-apoA-1) to the 10-year Framingham cardiovascular risk score (FRS) significantly improves prediction of cardiovascular events in patients with rheumatoid arthritis, according to a study published online Feb. 2 in Arthritis Care & Research.
Biomarker Linked to Arthritis Severity at Hip but Not Knee
WEDNESDAY, Feb. 15 (HealthDay News) -- A new biomarker is associated with osteoarthritis severity at the hip but not the knee, according to a study published in the Feb. 10 issue of the Journal of Biological Chemistry.
Fibromyalgia Symptoms More Severe in Obese Patients
TUESDAY, Feb. 14 (HealthDay News) -- Patients with fibromyalgia who are severely obese have more severe symptoms and lower quality of life (QOL), according to a study published in the February issue of Arthritis Care & Research.
Cancer Risk Higher in Children With Juvenile Arthritis
MONDAY, Feb. 13 (HealthDay News) -- Children with juvenile idiopathic arthritis (JIA) are significantly more likely to develop cancer than children without the condition, although common treatments have no effect on risk, according to a study published online Feb. 10 in Arthritis & Rheumatism.
Neuropsychiatric Events Have No Long-Term Impact in Lupus
WEDNESDAY, Feb. 8 (HealthDay News) -- Neuropsychiatric manifestations of systemic lupus erythematosus (SLE) are not associated with long-term disease activity, the accumulation of organ damage, or overall health-related quality of life, according to a study published online Jan. 30 in Arthritis Care & Research.
Subcortical Gray Matter Changes Seen in RA Patients
TUESDAY, Feb. 7 (HealthDay News) -- Compared with healthy control subjects, patients with rheumatoid arthritis (RA) have reduced intracranial volumes and structural changes in the subcortical gray matter, but do not have localized cortical gray matter atrophy, according to research published in the February issue of Arthritis & Rheumatism.
RA Drug Trial Funding Source Not Linked to Outcome
MONDAY, Feb. 6 (HealthDay News) -- Rheumatoid arthritis (RA) drug therapy randomized controlled trials (RCTs) funded by industry are not more likely to result in a positive outcome, according to research published online Jan. 24 in Arthritis & Rheumatism.
Weight Loss Impacts Leg Muscle, Strength in Knee OA
MONDAY, Feb. 6 (HealthDay News) -- In patients with osteoarthritis (OA) of the knee, a 16-week low-energy diet program results in independent losses of leg muscle tissue and strength, and is accompanied by improvements in body mass-normalized muscle strength, according to research published in the February issue of Arthritis & Rheumatism.
Proton Pump Inhibitor Use Ups Hip Fracture Risk for Women
WEDNESDAY, Feb. 1 (HealthDay News) -- Postmenopausal women are at a 35 percent increased risk of hip fractures if they regularly use proton pump inhibitors (PPIs), and that risk increases to more than 50 percent among women with a history of smoking, according to a study published online Jan. 31 in BMJ.
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