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Category: Internal Medicine | Monthly Briefing

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February 2012 Briefing - Internal Medicine

Last Updated: March 01, 2012.

 

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Here are what the editors at HealthDay consider to be the most important developments in Internal Medicine for February 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Nicotine Patches Don't Help Pregnant Women Stop Smoking

WEDNESDAY, Feb. 29 (HealthDay News) -- The addition of nicotine-replacement therapy to behavioral cessation support does not increase the rate of smoking abstinence in pregnant women, according to a study published in the March 1 issue of the New England Journal of Medicine.

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Amantadine Speeds Recovery From Consciousness Disorders

WEDNESDAY, Feb. 29 (HealthDay News) -- Amantadine improves the rate of functional recovery during active treatment in patients with severe traumatic brain injury, according to a study published in the March 1 issue of the New England Journal of Medicine.

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Ruxolitinib Reduces Spleen Size in Myelofibrosis

WEDNESDAY, Feb. 29 (HealthDay News) -- For patients with myelofibrosis, treatment with a potent and selective Janus kinase 1 and 2 inhibitor, ruxolitinib, provides significant clinical benefit compared with the best available treatment or placebo, according to two studies published in the March 1 issue of the New England Journal of Medicine.

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Bisphosphonates, Annual BMD Screen Up Fracture Prevention

WEDNESDAY, Feb. 29 (HealthDay News) -- In a hypothetical model of postmenopausal women receiving adjuvant aromatase inhibitors (AIs) for hormone receptor (HR)-positive early breast cancer (EBC), baseline and annual bone mineral density (BMD) screening followed by selective treatment with oral bisphosphonates for those diagnosed with osteoporosis is a cost-effective strategy, according to a study published online Feb. 27 in the Journal of Clinical Oncology.

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Despite Benefits of Selenium, Supplements May Be Harmful

WEDNESDAY, Feb. 29 (HealthDay News) -- While selenium is necessary for good health, levels that are too high can be harmful, and people whose serum selenium levels are already at least 122 µ/L should not take supplements, according to a review published online Feb. 29 in The Lancet.

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Group Art Therapy Not Found to Be Helpful in Schizophrenia

WEDNESDAY, Feb. 29 (HealthDay News) -- Group art therapy does not improve the mental health or social functioning of patients with schizophrenia, according to a study published online Feb. 28 in BMJ.

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Behavioral Intervention Slims Waistlines of Obese Men

WEDNESDAY, Feb. 29 (HealthDay News) -- A behavioral intervention to improve physical activity and diet in obese patients is more effective at slimming the waistlines of men than women, according to a study published online Feb. 27 in the Archives of Internal Medicine.

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Hearing Loss Linked to Falls in Those Under Age 70

WEDNESDAY, Feb. 29 (HealthDay News) -- Hearing loss is associated with increased odds of falling, according to research published in the Feb. 27 issue of the Archives of Internal Medicine.

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Statin Users Less Likely to Suffer From Depression

WEDNESDAY, Feb. 29 (HealthDay News) -- For patients with coronary heart disease, use of statins is associated with reduced risk of having or developing depression, according to a study published online Feb. 21 in the Journal of Clinical Psychiatry.

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Neurophysiological Deficits Persist Following Concussion

WEDNESDAY, Feb. 29 (HealthDay News) -- For athletes who suffer a concussion, neurophysiological deficits persist and are present at least six months following a concussion, and adolescents appear to be more vulnerable to the consequences of concussion, according to a study published in the March issue of Brain Injury.

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Family Tree Clarifies Risk of Death Due to Arrhythmia

WEDNESDAY, Feb. 29 (HealthDay News) -- In six inherited arrhythmia syndromes, the Family Tree Mortality Ratio (FTMR) method is useful for identifying the age during which mortality risk becomes manifest in an untreated population, according to research published online Feb. 28 in Circulation: Cardiovascular Genetics.

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Inactivity and Obesity Relate to Cognitive Impairment in Lupus

WEDNESDAY, Feb. 29 (HealthDay News) -- Physical inactivity and obesity are associated with impaired cognitive function, especially executive functions, in women with systemic lupus erythematosus (SLE), according to research published online Feb. 15 in Arthritis Care & Research.

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Care Protocol for Comatose Patients May Need Revision

WEDNESDAY, Feb. 29 (HealthDay News) -- Although neurological tests are highly reliable predictors of death in patients who remain in a coma following cardiopulmonary resuscitation (CPR), withdrawal-of-treatment decisions may need to be delayed for those who undergo mild hypothermia therapy, according to a Dutch study published in the February issue of the Annals of Neurology.

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Sleeping Pill Use Linked to Greater Mortality Risk

TUESDAY, Feb. 28 (HealthDay News) -- Even relatively small doses of sleeping pills are associated with a more than three-fold higher risk of death, according to a study published online Feb. 27 in BMJ Open.

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FDA Approves Label Changes for Statins

TUESDAY, Feb. 28 (HealthDay News) -- The recommendation to remove routine monitoring of liver enzymes is among safety label changes recently approved by the U.S. Food & Drug Administration for statins, according to a Feb. 28 Drug Safety Communication issued by the agency.

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Drug Ups Effect of Gemcitabine in Pancreatic Cancer

TUESDAY, Feb. 28 (HealthDay News) -- The efficacy of gemcitabine in treating pancreatic cancer can be greatly improved by a second drug that increases gemcitabine levels by preventing its breakdown, according to a study published online Feb. 28 in Cancer Discovery.

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BPA Exposure Possibly Linked to Future Heart Disease

TUESDAY, Feb. 28 (HealthDay News) -- Healthy people exposed to higher levels of the controversial chemical bisphenol A (BPA), found in plastics, may be more likely to develop heart disease, according to a study published online Feb. 21 in Circulation.

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Fast Heart Rate Predictive of Cardiac Events in High-Risk HTN

TUESDAY, Feb. 28 (HealthDay News) -- A fast heart rate is a strong predictor of adverse cardiac events in patients with high-risk hypertension, according to a study published in the March 1 issue of The American Journal of Cardiology.

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Adults With Disabilities at Increased Risk of Violence

TUESDAY, Feb. 28 (HealthDay News) -- Adults with disabilities face an increased risk of violence, with an even higher risk evident for those with mental illness, according to a review published online Feb. 28 in The Lancet.

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Dose-Response Link Between Tanning Bed Use, Skin Cancer

TUESDAY, Feb. 28 (HealthDay News) -- Use of tanning beds, especially in high school and college, is associated with an increased risk of skin cancer, according to a study published online Feb. 27 in the Journal of Clinical Oncology.

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Vitamin D Linked to Reduced Pain in Primary Dysmenorrhea

TUESDAY, Feb. 28 (HealthDay News) -- Treatment with cholecalciferol, which rapidly enhances 25-hydroxyvitamin D3 (25[OH]D), is associated with decreased pain and reduced nonsteroidal anti-inflammatory drug (NSAID) use for women with primary dysmenorrhea, according to a letter published in the Feb. 27 issue of the Archives of Internal Medicine.

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A-Fib Increases Risk of Cognitive, Functional Decline

TUESDAY, Feb. 28 (HealthDay News) -- Patients with atrial fibrillation are at an increased risk for both cognitive and functional decline, regardless of whether they have a stroke, according to research published online Feb. 27 in CMAJ, the journal of the Canadian Medical Association.

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Rapid Flu Tests Effective for Ruling In (But Not Out) Diagnosis

TUESDAY, Feb. 28 (HealthDay News) -- Rapid influenza tests are useful for diagnosing influenza; and oral oseltamivir and inhaled zanamivir may be beneficial for the treatment of influenza, according to two reviews published online Feb. 27 in the Annals of Internal Medicine.

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Less Than Half of New Diabetes Patients Achieve A1C Goals

TUESDAY, Feb. 28 (HealthDay News) -- Less than half of newly diagnosed patients with type 2 diabetes achieve A1C <7 percent, and those that do achieve it more likely started with lower A1C levels, according to a study published in the March issue of Diabetes Care.

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Poor Asthma Control Prevalent in the United States

MONDAY, Feb. 27 (HealthDay News) -- Many patients with asthma who do not use controller medications have persistent disease, and among those patients who do use controller medications, few have well-controlled disease, according to a study published in the March issue of the Annals of Allergy, Asthma & Immunology.

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Low Back Pain Counseling Strategy Ups Return to Work

MONDAY, Feb. 27 (HealthDay News) -- Combining a disability evaluation with proactive counseling for workers with low back pain (LBP) results in a higher return-to-work rate, which is statistically significant at one year, according to a study published online Feb. 16 in Spine.

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Chemo for Breast Cancer Tied to Long-Term Cognitive Issues

MONDAY, Feb. 27 (HealthDay News) -- Women treated with cyclophosphamide, methotrexate, and fluorouracil (CMF) chemotherapy for breast cancer still experience neuropsychological problems decades later, according to a study published online Feb. 27 in the Journal of Clinical Oncology.

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Red Blood Cell Omega-3 Levels Linked to Brain Volume

MONDAY, Feb. 27 (HealthDay News) -- In adults without clinical dementia, low red blood cell (RBC) levels of omega-3 fatty acids are associated with smaller brain volumes and lower scores on tests of visual memory and executive function, according to a study published in the Feb. 28 issue of Neurology.

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Heartburn Controlled With Step Down to Once Daily Therapy

MONDAY, Feb. 27 (HealthDay News) -- The majority of gastroesophageal reflux disease (GERD) patients who take twice-daily proton pump inhibitor (PPI) therapy, are able to successfully step down to management of heartburn with a daily dose of dexlansoprazole modified release (MR), according to a study published in the March issue of Clinical Gastroenterology and Hepatology.

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TAK-875 Improves Glycemic Control in Type 2 Diabetes

MONDAY, Feb. 27 (HealthDay News) -- For patients with type 2 diabetes who do not respond to diet or metformin treatment, selective pharmacological activation of the free fatty acid receptor 1 (FFAR1) by TAK-875 improves glycemic control, according to a phase 2 study published online Feb. 27 in The Lancet.

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Multimodal Palliative Approach OK for Advanced Esophageal CA

MONDAY, Feb. 27 (HealthDay News) -- For patients with advanced esophageal cancer, use of an individualized, multimodal approach with palliative intention achieves an acceptable mean survival time, with initial use of photodynamic therapy (PDT) offering significantly longer median survival compared to other modalities, according to the results of a single medical center study published online Feb. 14 in Lasers in Surgery and Medicine.

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Many Obese With CKD Want to Lose Weight

MONDAY, Feb. 27 (HealthDay News) -- Many overweight patients with chronic kidney disease (CKD) want to lose weight and are utilizing weight loss methods that may further kidney damage, according to a study published online Jan. 31 in the International Journal of Obesity.

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Combo of Diabetes, Depression Increases Post-MI Mortality

MONDAY, Feb. 27 (HealthDay News) -- Having both diabetes and depression significantly increases the risk of dying in the years following a heart attack, beyond the increased risk from either condition alone, according to a study published in the March issue of Diabetes Care.

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Ten-Year CML Survival Estimate of 68 Percent With Imatinib

MONDAY, Feb. 27 (HealthDay News) -- For patients with chronic myeloid leukemia that fails to respond to interferon alpha therapy, treatment with imatinib is associated with long-term survival of 68 percent, according to a study published online Feb. 27 in Cancer.

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Body Clock Linked to Sudden Cardiac Death

FRIDAY, Feb. 24 (HealthDay News) -- A body clock-dependent protein is associated with variations in electrical stability in the heart, which may explain why people are at higher risk of sudden cardiac death in the morning, according to research published online Feb. 22 in Nature.

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Older Anesthesiologists Have Higher Litigation Rates

FRIDAY, Feb. 24 (HealthDay News) -- Anesthesiologists over the age of 65 years have a higher frequency of litigation and greater severity of injury than their younger counterparts, according to an article published in the March issue of Anesthesiology.

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Variable Mortality Risk for Antipsychotic Use in Elderly

FRIDAY, Feb. 24 (HealthDay News) -- The risk of mortality associated with antipsychotic drug use among elderly residents in nursing homes in the United States varies between drugs, according to a study published online Feb. 23 in BMJ.

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Male Pattern Baldness Linked to Prostate Symptoms

FRIDAY, Feb. 24 (HealthDay News) -- Early-onset of male pattern baldness (androgenetic alopecia [AGA]) may be a marker of male urinary symptoms associated with an enlarged prostate, according to a study published in the March issue of the Journal of the American Academy of Dermatology.

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UVB Preferred for Treatment of Moderate to Severe Psoriasis

FRIDAY, Feb. 24 (HealthDay News) -- Ultraviolet B (UVB) is preferred by dermatologists for first-line treatment of moderate to severe psoriasis in both healthy male and female patients, according to a study published in the March issue of the Journal of the American Academy of Dermatology.

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Expression of Genes for Platelet Aggregation Up Post-CABG

FRIDAY, Feb. 24 (HealthDay News) -- Following coronary artery bypass graft (CABG) surgery, there is increased expression of genes involved in platelet aggregation, including cyclooxygenase-1 (COX1), glycoprotein (GP)IIb and GPIIIa, according to a study published online Feb. 13 in the Journal of Thrombosis and Haemostasis.

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Bolus Calculation, Flexible Insulin Up Diabetes Control

FRIDAY, Feb. 24 (HealthDay News) -- A structured course teaching the benefits of automated bolus calculator (ABC) use and flexible intensive insulin therapy (FIIT) improves metabolic control and satisfaction in patients with type 1 diabetes, according to a study published online Feb. 16 in Diabetes Care.

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Timeliness of Diagnosis Varies by Cancer and Patient

FRIDAY, Feb. 24 (HealthDay News) -- There is wide variation between cancer types in the proportion of patients who visit their general practitioner three or more times before being referred to the hospital, according to a study published online Feb. 24 in The Lancet Oncology.

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Plasma Protein S100-B Useful Screening Tool in Head Trauma

FRIDAY, Feb. 24 (HealthDay News) -- Measuring plasma levels of the protein S100-B has a high negative predictive value compared with computed tomography (CT) scans for patients with minor head injuries, according to research published in the March issue of the Annals of Emergency Medicine.

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Complications Seen in 40 Percent of Living Liver Donors

FRIDAY, Feb. 24 (HealthDay News) -- Complications of living donor hepatic lobectomy occur in 40 percent of cases, with the vast majority resolving within one year, according to research published online Feb. 15 in the American Journal of Transplantation.

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Model Predicts Death Due to Acetaminophen Overdose

FRIDAY, Feb. 24 (HealthDay News) -- Model for Acetaminophen-induced Liver Damage (MALD), a mathematical model that utilizes commonly obtained laboratory values, including overdose amount and time elapsed since overdose, is effective for predicting outcomes in patients with acute liver failure due to acetaminophen overdose, according to research published online Feb. 13 in Hepatology.

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Citrus Fruit Linked to Lower Risk of Ischemic Stroke

THURSDAY, Feb. 23 (HealthDay News) -- Eating higher amounts of a compound (flavonoid) found in citrus fruits may lower the risk of stroke, according to a study published online Feb. 23 in Stroke.

Abstract
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Virtual Colonoscopy Useful in Screening Older Adults

THURSDAY, Feb. 23 (HealthDay News) -- Computed tomography (CT) colonography is useful as a primary screening method for detecting colorectal neoplasia in adults over the age of 65 years, with sensitivity and specificity similar to that seen for younger adults, according to research published online Feb. 23 in Radiology.

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WHO Criteria May Overestimate Fatality Rate for Avian Flu

THURSDAY, Feb. 23 (HealthDay News) -- Based on cases in hospitalized patients confirmed by the World Health Organization (WHO), the current estimated overall case fatality rate for H5N1 infection in humans is greater than 50 percent, but the stringent criteria for confirmation of the infection mean the actual fatality rate may be much lower, according to a meta-analysis published online Feb. 23 in Science.

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Family History Ups Risk of Differentiated Thyroid Cancer

THURSDAY, Feb. 23 (HealthDay News) -- Family history of thyroid cancer in a first-degree relative may be associated with an increased risk of sporadic differentiated thyroid carcinoma (DTC), according to a study published in the March 1 issue of Cancer.

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Aspirin and Clopidogrel Improve Claudication Distance

THURSDAY, Feb. 23 (HealthDay News) -- In patients with stable intermittent claudication due to peripheral arterial disease, low-dose aspirin appears to work as well as clopidogrel when given in conjunction with walking rehabilitation to improve initial claudication distance (ICD) and absolute claudication distance (ACD), according to research published in the February issue of the Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease.

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Stability Predicts Treatment Success for Vitiligo

THURSDAY, Feb. 23 (HealthDay News) -- In patients with vitiligo, a depigmenting disorder characterized by loss of melanocytes from the epidermis, melanocyte transplantation is more likely to be successful in patients whose disease has been stable for longer periods, according to a study published online Feb. 13 in the British Journal of Dermatology.

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Bisphosphonate Use Linked to Reduced Colorectal Cancer Risk

THURSDAY, Feb. 23 (HealthDay News) -- Exposure to bisphosphonates (BPs) is associated with a reduction in the risk of colorectal cancer (CRC), a reduction that is significant only for risedronic acid, according to a study published in the March 1 issue of Cancer.

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Pseudo-Prospective Analyses ID Alcohol Recovery Correlates

THURSDAY, Feb. 23 (HealthDay News) -- Prospective analysis of correlates of alcohol recovery compare favorably with pseudo-prospective studies with time-dependent covariates, but differ from cross-sectional analyses, according to a study published online Feb. 6 in Alcoholism: Clinical & Experimental Research.

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Cancer Risk Up in Bilateral Retinoblastoma Survivors

THURSDAY, Feb. 23 (HealthDay News) -- For survivors of bilateral retinoblastoma (Rb), family history is associated with an increased risk of second cancers (SCs), especially melanoma, according to a study published online Feb. 21 in the Journal of Clinical Oncology.

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Low Neuro-Psych Functioning for Long-Term Glioma Survivors

THURSDAY, Feb. 23 (HealthDay News) -- Long-term survivors of childhood high-grade glioma have intellectual functioning within low-average ranges and low neuropsychological functioning, but the majority of patients report within or above normal quality of life, according to a study published online Feb. 21 in the Journal of Clinical Oncology.

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Community Health Indicators Tied to Transplant Outcomes

WEDNESDAY, Feb. 22 (HealthDay News) -- In the community setting, health indicators are significantly associated with post-kidney-transplant mortality, according to a study published online Feb 20 in the Archives of Surgery.

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Metastatic Melanoma Responds to Vemurafenib

WEDNESDAY, Feb. 22 (HealthDay News) -- For more than 50 percent of patients with metastatic melanoma with V600 mutations in the serine-threonine protein kinase B-RAF (BRAF V600-mutant metastatic melanoma), treatment with vemurafenib is associated with clinical response, according to a phase 2 trial published in the Feb. 23 issue of the New England Journal of Medicine.

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Colonoscopic Removal of Adenomas Cuts CRC Mortality

WEDNESDAY, Feb. 22 (HealthDay News) -- Colonoscopic removal of adenomatous polyps reduces colorectal cancer mortality, and interim analysis shows that fecal immunochemical testing (FIT) yields similar results to colonoscopy; however, more polyps are identified with colonoscopy screening compared to FIT, according to two studies published in the Feb. 23 issue of the New England Journal of Medicine.

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Skin Cancer Frequency in Chronic Leg Ulcers >10 Percent

WEDNESDAY, Feb. 22 (HealthDay News) -- Chronic leg ulcers (CLUs) that don't heal after three months of appropriate treatment have an overall skin cancer frequency of 10.4 percent, according to a study published online Feb. 20 in the Archives of Dermatology.

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Elevated Homocysteine, Heart Disease Link Questioned

WEDNESDAY, Feb. 22 (HealthDay News) -- Elevated homocysteine levels are not associated with a greater risk of coronary heart disease when considering unpublished data, suggesting publication bias, according to a study available online Feb. 21 in PLoS Medicine.

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High VEGF Signaling Score Tied to Lung Cancer Prognosis

WEDNESDAY, Feb. 22 (HealthDay News) -- A high vascular endothelial growth factor (VEGF) signaling score correlates with good prognosis in patients with early squamous cell carcinoma (SCC) of the lung, according to a study published online Feb. 21 in the Journal of Clinical Oncology.

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Study IDs the Rationalizations of Social Smokers

WEDNESDAY, Feb. 22 (HealthDay News) -- Social smokers do not see themselves as addicted smokers and often smoke in response to group norms or because of excessive alcohol consumption, according to research published online Feb. 20 in Tobacco Control.

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Teenage Drinking Influenced by Media Exposure to Alcohol

WEDNESDAY, Feb. 22 (HealthDay News) -- Media exposure, including viewing films featuring alcohol and alcohol-related merchandise, influence both onset age of teenage alcohol consumption and binge drinking, whereas family drinking characteristics influence only onset age of alcohol consumption, according to a study published online Feb. 20 in BMJ Open.

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Highest Diabetes Death Rates Seen in Trials Selecting for CKD

WEDNESDAY, Feb. 22 (HealthDay News) -- In type 2 diabetes patients selected for randomized controlled trials (RCTs), chronic kidney disease (CKD) is associated with the highest overall risk of mortality, according to a review published online Feb. 21 in the Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease.

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Medtronic Stent Approved to Treat Coronary Artery Disease

TUESDAY, Feb. 21 (HealthDay News) -- Medtronic's Resolute Integrity Drug-Eluting Stent (DES) has been approved by the U.S. Food and Drug Administration for people with coronary artery disease (CAD), the Minneapolis-based company said in a news release.

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Replacing PPSV23 With PCV13 May Prevent More Pneumonia

TUESDAY, Feb. 21 (HealthDay News) -- A model shows that replacing the current 23-valent pneumococcal polysaccharide vaccine (PPSV23) with the 13-valent pneumococcal conjugate vaccine (PCV13) might prevent more pneumococcal disease, while remaining economically reasonable, according to a study published in the Feb. 22 issue of the Journal of the American Medical Association.

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Women With MI More Likely to Present Without Chest Pain

TUESDAY, Feb. 21 (HealthDay News) -- Women suffering a myocardial infarction (MI) are more likely than men of the same age to present without chest pain and have higher in-hospital mortality, according to a study published in the Feb. 22 issue of the Journal of the American Medical Association.

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MRSA Screening Protocol Aids in Peds Open Airway Surgery

TUESDAY, Feb. 21 (HealthDay News) -- A screening and antibiotic treatment regimen for methicillin-resistant Staphylococcus aureus (MRSA) in children undergoing open airway surgery may be helpful for minimizing MRSA-associated postoperative infections in MRSA-colonized patients, according to a study published in the February issue of the Archives of Otolaryngology -- Head & Neck Surgery.

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Insulin Acts As Satiety Signal in Postprandial Period

TUESDAY, Feb. 21 (HealthDay News) -- Brain insulin may act as a satiety signal during the postprandial period and is associated with decreased appetite and reduced intake of highly palatable food, according to a study published online Feb. 16 in Diabetes.

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Resistance Training Improves Outcomes in Type 2 Diabetes

TUESDAY, Feb. 21 (HealthDay News) -- For patients with type 2 diabetes, aerobic training and resistance training both result in improved metabolic features, insulin sensitivity, and reduced abdominal fat, according to a study published online Feb. 16 in Diabetes Care.

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Pharmacist-Led Intervention Reduces Medical Errors

TUESDAY, Feb. 21 (HealthDay News) -- For clinics with computerized medical records, a pharmacist-led intervention significantly reduces the risk of medical errors and is likely to be cost-effective, according to a study published online Feb. 21 in The Lancet.

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Alcohol Dependence Significant Problem for U.S. Surgeons

TUESDAY, Feb. 21 (HealthDay News) -- A considerable number of U.S. surgeons have alcohol abuse and dependence, which is more likely in those who have recently reported major errors, are burned out, and are depressed, according to a study published in the February issue of the Archives of Surgery.

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External Cooling Improves Outcomes in Septic Shock

TUESDAY, Feb. 21 (HealthDay News) -- Use of external cooling to achieve fever control is safe for sedated patients in septic shock, and decreases vasopressor requirements and early mortality, according to a study published online Feb. 17 in the American Journal of Respiratory and Critical Care Medicine.

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By 2007, Hep C Superseded HIV As Cause of Death in U.S.

MONDAY, Feb. 20 (HealthDay News) -- Hepatitis C virus (HCV) superseded HIV as a cause of death by 2007; and birth cohort screening is cost-effective for HCV, according to two studies published in the Feb. 21 issue of the Annals of Internal Medicine.

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Substituting Fructose for Other Carbs Doesn't Up Weight Gain

MONDAY, Feb. 20 (HealthDay News) -- Evidence suggests that fructose is unlikely to cause weight gain when substituted for other carbohydrates in diets with similar numbers of calories, but does increase weight gain in hypercaloric diets, according to a review published in the Feb. 21 issue of the Annals of Internal Medicine.

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Infectious Disease Burden Rising in New Zealand

MONDAY, Feb. 20 (HealthDay News) -- Hospital admissions for infectious disease have risen over the last two decades in New Zealand, with infectious disease now being the biggest contributor to hospital admissions of any cause, particularly among the native population and the socioeconomically disadvantaged, according to a study published online Feb. 20 in The Lancet.

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Classification-Based Therapy No Better for Back Pain

MONDAY, Feb. 20 (HealthDay News) -- Treatment of patients with lower back pain (LBP) using a classification-based physical therapy approach shows no statistically significant superiority to treatment with usual physical therapy care, according to a study published online Feb. 13 in Spine.

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Group-Based Lifestyle Program Beneficial in Prediabetes

MONDAY, Feb. 20 (HealthDay News) -- A group-based diabetes education and lifestyle program is associated with improvements in healthy eating, physical activity, and motivation and mood, and reduces waist circumference and weight in individuals with prediabetes, according to a study published online Feb. 14 in Diabetes Care.

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CT Myelography More Accurately Detects CSF Leakage

MONDAY, Feb. 20 (HealthDay News) -- Cerebrospinal fluid (CSF) leakage may be detected more accurately in patients with spontaneous intracranial hypotension (SIH) using epidural collection on computed tomography myelography (CTM) rather than paraspinal radioisotope (RI) accumulation on radioisotope cisternography (RIC), according to a study published in the Feb. 15 issue of Spine.

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Nicotine Replacement Therapy Linked With Infantile Colic

MONDAY, Feb. 20 (HealthDay News) -- Maternal smoking or use of nicotine replacement therapy (NRT) during pregnancy is associated with increased risk of infantile colic in offspring, according to a study published online Feb. 20 in Pediatrics.

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Lipid Sensor GPR120 Linked to Obesity in Mice and Humans

MONDAY, Feb. 20 (HealthDay News) -- A protein that acts as a lipid sensor, GPR120, can lead to obesity when defective in mice and humans, according to a study published online Feb. 19 in Nature.

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High Uric Acid Level Predictive of Adverse Cardiac Events

FRIDAY, Feb. 17 (HealthDay News) -- A high serum uric acid level is an independent predictor of in-hospital and long-term adverse cardiac events in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI), according to research published in the Feb. 15 issue of The American Journal of Cardiology.

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Pregnancy Complications Tied to CVD Later in Life

FRIDAY, Feb. 17 (HealthDay News) -- Pregnancy-related complications, including hypertensive disorders and diabetes, may identify women at increased risk of cardiovascular disease (CVD) later in life, according to a study published online Feb. 17 in Circulation.

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MRI Alone Not Ideal in Pulmonary Embolism Diagnosis

FRIDAY, Feb. 17 (HealthDay News) -- Magnetic resonance imaging (MRI) should not be used as a stand-alone test to diagnose pulmonary embolism (PE), according to a study published online Feb. 9 in the Journal of Thrombosis and Haemostasis.

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Open-Angle Glaucoma Linked to Erectile Dysfunction

FRIDAY, Feb. 17 (HealthDay News) -- Men with erectile dysfunction (ED) are almost three times more likely to have been previously diagnosed with glaucoma, according to a study published in the February issue of Ophthalmology.

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2002 to 2008 Saw Increase in Partial Nephrectomy Use

FRIDAY, Feb. 17 (HealthDay News) -- In the United States, the use of partial nephrectomy procedures to manage renal masses in patients with renal cell carcinoma (RCC) increased significantly from 2002 to 2008, according to research published in the March issue of The Journal of Urology.

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Study Evaluates Clinical Value of Stroke Biomarkers

FRIDAY, Feb. 17 (HealthDay News) -- While 136 different stroke biomarkers have been identified, the clinical value of these biomarkers remains unclear, according to a study published online Feb. 9 in the British Journal of Clinical Pharmacology.

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Smoking Cessation Drug May Also Reduce Drinking

FRIDAY, Feb. 17 (HealthDay News) -- The smoking cessation drug varenicline (VAR) may also reduce alcohol consumption in social drinkers by increasing alcohol's aversive effects, according to a study published online Feb. 16 in Alcoholism: Clinical & Experimental Research.

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Microchip-Based Drug Delivery of hPTH(1-34) Safe in Humans

THURSDAY, Feb. 16 (HealthDay News) -- An implantable microchip-based drug delivery device can safely be used to deliver human parathyroid hormone fragment (hPTH[1-34]), according to a study published online Feb. 16 in Science Translational Medicine to coincide with presentation at the annual meeting of the American Association for the Advancement of Science, held from Feb. 16 to 20 in Vancouver, Canada.

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Chickens Harbor E. coli Found in Human UTIs

THURSDAY, Feb. 16 (HealthDay News) -- Retail purchased chicken may be the source of extraintestinal pathogenic Escherichia coli (ExPEC) that causes urinary tract infections (UTIs) in humans, according to a study published online Feb. 15 in Emerging Infectious Diseases.

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Smoking Bans Lead to Less, Not More, Smoking at Home

THURSDAY, Feb. 16 (HealthDay News) -- Smoke-free legislation leads to less smoking in smokers' homes, not more, according to research published online Feb. 13 in Tobacco Control.

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High Omega-3 Intake Slows Rate of Visual Acuity Decline

THURSDAY, Feb. 16 (HealthDay News) -- For patients with typical retinitis pigmentosa, treatment with vitamin A combined with an omega-3-rich diet slows the decline in distance and retinal visual acuities, according to a study published online Feb. 13 in the Archives of Ophthalmology.

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Nutrition Therapy Does Not Improve Cancer Mortality Rate

THURSDAY, Feb. 16 (HealthDay News) -- Nutritional intervention may improve quality of life (QOL) measures in cancer patients with malnutrition, but has no effect on survival rates, according to a study published online Feb. 15 in the Journal of the National Cancer Institute.

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Editorial

TTN Mutation Detection Aids Cardiomyopathy Diagnosis

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