The annual meeting of the American Academy of Allergy, Asthma & Immunology (AAAAI) was held from March 2 to 6 in Orlando, Fla., and attracted approximately 5,500 participants from around the world, including clinicians, academicians, allied health professionals, and others interested in allergic and immunologic disease. The conference highlighted recent advances in the field, with presentations and abstracts focusing on clinical developments in allergy, asthma, and immunologic diseases.
In one study, Robert A. Wood, M.D., of the Johns Hopkins Children's Center in Baltimore, and colleagues compared the efficacy of oral immunotherapy versus sublingual immunotherapy.
"A second objective was to evaluate whether initial sublingual immunotherapy was associated with fewer side effects than oral immunotherapy. We found that initiation of treatment with sublingual immunotherapy resulted in fewer side effects as compared with oral immunotherapy," Wood said. "Therefore, this study suggests that sublingual immunotherapy can be used for adults who've had a problem tolerating oral immunotherapy in the past, as it is associated with a reduced side effect profile."
In another study, Tetsuo Shoda, M.D., Ph.D., of the National Center for Child Health and Development in Tokyo, and colleagues identified possible risk factors, in addition to tacrolimus therapy, for the development of food allergy in children after pediatric liver transplantation.
"Our analysis revealed two important clinical findings. First, the cumulative incidence of food allergy developing after liver transplantation differed according to the primary liver disease. Second, a history of previous intestinal surgery was a significant risk factor for the development of food allergy after liver transplantation," Shoda said. "We believe that a more precise further clarification of these associations in future studies would allow us to determine whether new interventions could decrease the rate of food allergy development in this population."
In an effort to improve diagnosis and management of allergies, asthma, and immune deficiencies, Dennis Ledford, M.D., of the University of South Florida College of Medicine in Tampa, and colleagues announced the International Collaboration in Asthma, Allergy and Immunology (iCAALL) initiative. Multiple organizations will be participating in this new initiative, including the AAAAI, the American College of Allergy, Asthma & Immunology, the European Academy of Allergy and Clinical Immunology, and the World Allergy Organization.
"iCAALL brings together the largest, most influential related professional organizations in a global effort to improve care of patients with asthma and allergic and immunologic diseases and to better insure physicians are well informed on the latest research and consensus on the diagnosis and management of these conditions," Ledford said. "The initiative aims for worldwide distribution of consensus summaries on how to apply research findings to the care of asthma and allergic and immunologic diseases."
One key focus of the iCAALL initiative is the release of a series of International Consensus reports.
"These reports will be released during the respective organizations' annual meetings and will aid in improving the management and treatment of asthma and allergic and immunologic diseases. The first of these reports was presented this week at the AAAAI annual meeting. It focuses on food allergy diagnosis and management," Ledford said.
AAAAI: 2000 to 2009 Saw Rise in Angioedema Hospitalizations
TUESDAY, March 6 (HealthDay News) -- The rate of angioedema hospitalization has increased over the last decade, especially among African-Americans, according to a study presented at the annual meeting of the American Academy of Allergy, Asthma & Immunology, held from March 2 to 6 in Orlando, Fla.
AAAAI: Prevalence of Asthma, Hay Fever Lower Among Amish
MONDAY, March 5 (HealthDay News) -- The prevalence of asthma, hay fever, and allergic sensitization is significantly lower among the Amish population than among Swiss children, according to a study presented at the annual meeting of the American Academy of Allergy, Asthma & Immunology, held from March 2 to 6 in Orlando, Fla.
AAAAI: Corticosteroid Response in Asthma Impacted by BMI
MONDAY, March 5 (HealthDay News) -- For children with asthma, an increased body mass index (BMI) is associated with a decreased response to corticosteroids (CS) and increased daily requirements for inhaled CS (ICS), according to a study presented at the annual meeting of the American Academy of Allergy, Asthma & Immunology, held from March 2 to 6 in Orlando, Fla.
AAAAI: Asthma Patients More Tolerant of Food Challenges
MONDAY, March 5 (HealthDay News) -- Asthma patients with a history of food allergy are less likely than similar individuals without asthma to fail an oral food challenge, according to a study presented at the annual meeting of the American Academy of Allergy, Asthma & Immunology, held from March 2 to 6 in Orlando, Fla.
AAAAI: Third Trimester Smoke Exposure Affects Infant Skin
MONDAY, March 5 (HealthDay News) -- Maternal exposure to tobacco smoke during the third trimester of pregnancy is associated with a significantly increased prevalence of atopic eczema/dermatitis syndrome (AEDS) in infants, according to a study presented at the annual meeting of the American Academy of Allergy, Asthma & Immunology, held from March 2 to 6 in Orlando, Fla.
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