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Category: Internal Medicine | Monthly Briefing

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March 2012 Briefing - Internal Medicine

Last Updated: April 02, 2012.

 

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Here are what the editors at HealthDay consider to be the most important developments in Internal Medicine for March 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Liver Cancer Patients Less Likely to Die on Transplant List

FRIDAY, March 30 (HealthDay News) -- Liver transplantation candidates with hepatocellular carcinoma (HCC) have significantly lower 90-day odds of waitlist removal due to clinical deterioration or death compared to non-HCC candidates with similar Model for End-Stage Liver Disease (MELD) scores, according to a study published in the April issue of Liver Transplantation.

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Three Susceptibility Loci Confirmed for SLE

FRIDAY, March 30 (HealthDay News) -- A large genome-wide association study has replicated three systemic lupus erythematosus (SLE) loci, according to research published online March 29 in the American Journal of Human Genetics.

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Room for Improvement in Ob-Gyn Communication About Sex

FRIDAY, March 30 (HealthDay News) -- About two-thirds of obstetrician/gynecologists (Ob-Gyns) ask patients about their sexual activities, but other aspects of sexuality, including satisfaction with sex and sexual identity, are not routinely discussed, according to a study published online March 22 in The Journal of Sexual Medicine.

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Swimming Improves Vascular Function, BP in Older Adults

FRIDAY, March 30 (HealthDay News) -- Swimming exercise is associated with a decrease in blood pressure (BP) and improvements in vascular function in older adults with early hypertension, according to a study published in the April 1 issue of The American Journal of Cardiology.

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Lasers Remove Inches From Fat Trouble Spots

FRIDAY, March 30 (HealthDay News) -- Low-level laser therapy (LLLT) is effective for body slimming, according to a study published in the March issue of Lasers in Surgery and Medicine.

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Maternal and Child Health Inequalities Found Worldwide

FRIDAY, March 30 (HealthDay News) -- As part of Countdown to 2015, substantial variation has been identified between countries and interventions with respect to coverage levels of maternal, neonatal, and child health interventions, according to a study published in the March 31 issue of The Lancet.

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HIV Superinfection Broadens Immune Response in Women

FRIDAY, March 30 (HealthDay News) -- Sequential HIV infections lead to the development of a broad neutralizing antibody (NAb) response, according to a study published online March 29 in PLoS Pathogens.

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Cardiac Shock Wave Therapy Improves Angina Symptoms

FRIDAY, March 30 (HealthDay News) -- Cardiac shock wave therapy (CSWT) can significantly improve symptoms, ischemic threshold during exercise, and specific quality-of-life parameters for patients with chronic refractory angina pectoris, according to a study published online March 23 in Cardiovascular Therapeutics.

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Adherence to Cancer Surveillance Guidelines Varies

FRIDAY, March 30 (HealthDay News) -- Insured breast cancer survivors have high rates of guideline-recommended recurrence testing and non-recommended metastatic testing, while only about half of colorectal cancer survivors undergo recommended surveillance and two-thirds receive non-recommended metastatic testing, according to a study published online March 20 in Cancer.

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Similar Rates of Depression After Stroke and TIA

FRIDAY, March 30 (HealthDay News) -- The frequency of depression and newly identified depression rates are similar following a stroke or transient ischemic attack (TIA), according to a study published online March 29 in Stroke.

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Poor Health-Related Function, Diabetes Combo Ups Death Risk

FRIDAY, March 30 (HealthDay News) -- The combination of type 2 diabetes and impaired health-related functioning (HRF) is associated with an increased risk of cardiovascular disease (CVD) mortality, according to a study published online March 23 in Diabetes Care.

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Better Short-Term Outcomes for Private Prostatectomies

FRIDAY, March 30 (HealthDay News) -- For men undergoing radical prostatectomies (RPs), private health insurance coverage is linked with fewer complications, less in-hospital recovery time, and decreased mortality, compared to public coverage, according to a study published in the April 1 issue of Cancer.

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Electrocorticographic Signals May Restore Arm Movement

THURSDAY, March 29 (HealthDay News) -- Electrocorticography (ECoG) signals from patients with chronic motor dysfunction represent motor information that may be useful for controlling prosthetic arms, according to a study published in the March issue of the Annals of Neurology.

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Stigma Affects Depression Among Lung Cancer Patients

THURSDAY, March 29 (HealthDay News) -- For patients with lung cancer, perceived stigma is significantly associated with depressive symptomatology, according to a study published in the March issue of Psycho-Oncology.

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Polymorphism in Opioid Gene Affects Breast Cancer Survival

THURSDAY, March 29 (HealthDay News) -- Genotype at the A118G polymorphism of the µ-opioid receptor gene is associated with breast cancer-specific mortality, according to a study published in the April issue of Anesthesiology.

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Statin Discontinuation Linked to Mortality in RA Patients

THURSDAY, March 29 (HealthDay News) -- Patients with rheumatoid arthritis are at higher risk of death from cardiovascular and non-cardiovascular causes if they discontinue statin treatment, according to a study published online March 29 in Arthritis Care & Research.

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Antibodies Effective Against Plaque Psoriasis

THURSDAY, March 29 (HealthDay News) -- Antibodies targeting interleukin-17 or its receptor are effective in treating moderate-to-severe plaque psoriasis, according to two studies published in the March 29 issue of the New England Journal of Medicine.

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Ratio of Amyloid Biomarkers Predicts Alzheimer's Risk

THURSDAY, March 29 (HealthDay News) -- The ratio of two plasma amyloid-β (Aβ) biomarkers is associated with the development of Alzheimer's disease (AD) and dementia, according to a review published online March 26 in the Archives of Neurology.

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Point-of-Care Genetic Testing Feasible After PCI

THURSDAY, March 29 (HealthDay News) -- For patients who undergo percutaneous coronary intervention (PCI), point-of-care genetic testing is feasible and identifies carriers of a CYP2C19*2 allele with high sensitivity and specificity, according to a proof-of-concept study published online March 29 in The Lancet.

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Chemo-Linked Factors May Impact Weight in Breast Cancer

THURSDAY, March 29 (HealthDay News) -- Adjuvant chemotherapy for early-stage breast cancer can induce weight gain and a variety of metabolic changes that may be associated with a poor prognosis for some patients, according to research published in the April issue of Obesity Reviews.

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Lifestyle Factors Linked to Slower Progression in MS

THURSDAY, March 29 (HealthDay News) -- There is an inverse association between the consumption of alcoholic beverages, coffee, and fish and time to disability progression in people with relapsing onset multiple sclerosis (MS), but not in those with progressive onset MS, according to research published in the April issue of the European Journal of Neurology.

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Study Finds Psoriasis Treatment Increases Skin Cancer Risk

THURSDAY, March 29 (HealthDay News) -- The long-term risk of squamous cell carcinoma (SCC) is significantly increased for patients with severe psoriasis who receive more than 350 psoralen and ultraviolet A (PUVA) treatments compared with those who receive fewer than 50 treatments, according to research published in the April issue of the Journal of the American Academy of Dermatology.

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Prophylaxis With Apixaban Feasible for Cancer Patients

THURSDAY, March 29 (HealthDay News) -- Primary venous thromboembolism prophylaxis with apixaban, an oral direct Factor Xa inhibitor, in ambulatory cancer patients undergoing first- or second-line chemotherapy for advanced or metastatic cancer, is safe and well tolerated, according to a phase II study published online March 12 in the Journal of Thrombosis and Haemostasis.

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Pay for Performance Does Not Improve Mortality Rates

WEDNESDAY, March 28 (HealthDay News) -- Participation in the Medicare Premier Hospital Quality Incentive Demonstration (Premier HQID) program does not lead to lower 30-day mortality rates, according to a study published online March 28 in the New England Journal of Medicine.

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Change in Health Insurance Status Linked to ER Use

WEDNESDAY, March 28 (HealthDay News) -- Recent changes in health insurance status are linked to greater emergency department use by newly insured and newly uninsured adults, according to a study published online March 26 in the Archives of Internal Medicine.

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Lifestyle Intervention Helps Overweight Diabetes Patients

WEDNESDAY, March 28 (HealthDay News) -- An intensive lifestyle intervention leads to a significant reduction in the risk of mobility-related disability in overweight type 2 diabetes patients, as compared with diabetes support and education, according to a study published in the March 29 issue of the New England Journal of Medicine.

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Antipsychotic Medications Increase Risk of Heart Attack

WEDNESDAY, March 28 (HealthDay News) -- For older patients treated with cholinesterase inhibitors, taking antipsychotic agents (APs) for dementia is associated with a modest and time-limited increased risk of myocardial infarction (MI), according to a study published online March 26 in the Archives of Internal Medicine.

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Genetic Variants Explain Podoconiosis

WEDNESDAY, March 28 (HealthDay News) -- Genetic variants in the HLA class II region are associated with podoconiosis, a tropical lymphedema resulting from long-term barefoot exposure to soil derived from volcanic rock, according to a study published in the March 29 issue of the New England Journal of Medicine.

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Vaccine Cuts Risk of Subsequent HPV-Related Disease

WEDNESDAY, March 28 (HealthDay News) -- Women surgically treated for human papillomavirus (HPV)-related disease who were previously vaccinated with the quadrivalent HPV vaccine have reduced incidence of subsequent HPV-related disease, according to a study published online March 27 in BMJ.

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National Survey Describes Cancer-Related Deaths in India

WEDNESDAY, March 28 (HealthDay News) -- Most cancer-related deaths in India occur in those aged 30 to 69 years, with tobacco-related cancers accounting for a considerable proportion of cancer-related deaths, according to a study published online March 28 in The Lancet.

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Moderate Drinking Cuts Mortality in MI Survivors

WEDNESDAY, March 28 (HealthDay News) -- Men who have survived a myocardial infarction (MI) benefit from moderate alcohol consumption, with long-term consumption inversely associated with all-cause and cardiovascular mortality, according to a study published online March 27 in the European Heart Journal.

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Early Immunotherapy May Benefit Autoimmune Epilepsy

WEDNESDAY, March 28 (HealthDay News) -- Patients suspected of having autoimmune epilepsy that fails to respond to anti-epileptic drugs may benefit from early immunotherapy, according to a study published online March 26 in the Archives of Neurology.

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Invasive Strategy Ups Survival in Myotonic Dystrophy 1

WEDNESDAY, March 28 (HealthDay News) -- An invasive strategy, based on prophylactic permanent pacing, is associated with longer survival for patients with myotonic dystrophy type 1, according to a study published in the March 28 issue of the Journal of the American Medical Association.

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Extended-Release Niacin Raises Fasting Glucose Levels

WEDNESDAY, March 28 (HealthDay News) -- The combination of extended-release niacin (N) with ezetimibe plus simvastatin (E/S) to treat hyperlipidemia is associated with increased fasting glucose (FG) levels compared with E/S alone, but these cases tend to be transient and remit without intervention, according to research published in the April issue of Diabetes Care.

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Early, Temporary HIV Treatment Reduces Viral Load

WEDNESDAY, March 28 (HealthDay News) -- Treating HIV patients with antiretroviral drugs temporarily when they are first infected reduces viral load and lengthens the time off treatment, according to a study published online March 27 in PLoS Medicine.

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Non-HDL Cholesterol Tied to Risk of Cardiovascular Event

TUESDAY, March 27 (HealthDay News) -- On-treatment levels of non-high-density lipoprotein cholesterol (non-HDL-C) and, to a lesser extent, low-density lipoprotein cholesterol (LDL-C) and apolipoprotein B (apoB) are each associated with risk of future major cardiovascular events for patients on statin therapy, according to a study published in the March 28 issue of the Journal of the American Medical Association.

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Chocolate Consumption Tied to Lower Body Mass Index

TUESDAY, March 27 (HealthDay News) -- More frequent chocolate intake is linked to a lower body mass index (BMI), according to a research letter published in the March 26 issue of the Archives of Internal Medicine.

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Review Compares Drug Options for Irritable Bowel Syndrome

TUESDAY, March 27 (HealthDay News) -- Tricyclic antidepressants and alosetron are associated with significant harm in treating irritable bowel syndrome (IBS) compared with rifaximin, and selective serotonin reuptake inhibitors (SSRIs) and lubiprostone appear to be safe, according to a meta-analysis published in the April issue of The American Journal of Medicine.

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Prolonged Sitting Increases All-Cause Mortality Risk

TUESDAY, March 27 (HealthDay News) -- People over the age of 45 years who sit for prolonged periods of time each day are at an increased risk of death due to all causes, compared with those who sit for less than four hours/day, according to research published in the March 26 issue of the Archives of Internal Medicine.

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Insulin Resistance Increases Risk of Colorectal Adenomas

TUESDAY, March 27 (HealthDay News) -- Insulin resistance (IR) and central obesity, as measured by waist to hip ratio (WHR), are associated with a significantly increased risk of colorectal adenomas, especially in men, according to a study published in the April 1 issue of Cancer.

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Dual Mode Laser Therapy Effectively Treats Acne Vulgaris

TUESDAY, March 27 (HealthDay News) -- A series of Nd:YAG laser treatments effectively and rapidly reduces both inflammatory and noninflammatory acne vulgaris lesions, according to a study published in the April issue of the Journal of the American Academy of Dermatology.

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New Guidelines Issued for Red Blood Cell Transfusions

MONDAY, March 26 (HealthDay News) -- A restrictive red blood cell transfusion strategy should be employed for hemodynamically stable adults and children, according to a clinical practice guideline issued by the AABB (formerly the American Association of Blood Banks) and published online March 26 in the Annals of Internal Medicine.

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Cervical Cancer Mortality Similar in U.S. and Netherlands

MONDAY, March 26 (HealthDay News) -- The cervical cancer screening program used by the Netherlands is as effective as the screening protocol used in the United States, producing similar cervical cancer mortality rates in spite of less screening, according to research published in the March issue of the Milbank Quarterly.

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Few Young Women With Cancer Pursue Fertility Preservation

MONDAY, March 26 (HealthDay News) -- Few women with cancer diagnosed before age 40 take steps to preserve their fertility during treatment, according to a study published online March 26 in Cancer.

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Common Blood Pressure Drugs Help Prevent Diabetes

FRIDAY, March 23 (HealthDay News) -- A common class of oral high blood pressure drugs is associated with improved survival of insulin-producing pancreatic β-cells and improved glucose homeostasis, according to a study published in the April issue of Diabetes.

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Transneuronal Spread Model Fits Neurodegenerative Disease

FRIDAY, March 23 (HealthDay News) -- Neurodegenerative diseases may be characterized by specific regions of the brain that are critical network epicenters, with disease-related vulnerability associated with shorter paths to the epicenter and greater total connectional flow, according to a study published in the March 22 issue of Neuron.

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Simple, Realistic Diet and Exercise Guidelines Needed

FRIDAY, March 23 (HealthDay News) -- Consumers need to be provided with simple, clearly written, realistic, and tailored guidelines for healthy eating, physical activity, and weight-related recommendations, according to research published online March 8 in Obesity Reviews.

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Fewer Mitochondria in Offspring of Parents With Diabetes

FRIDAY, March 23 (HealthDay News) -- Normal-weight, insulin-resistant individuals whose parents have type 2 diabetes have fewer mitochondria in their muscles due to lower expression of lipoprotein lipase (LPL), according to a study published in the April issue of Diabetes.

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New Device Approved for Lingering GERD

FRIDAY, March 23 (HealthDay News) -- The LINX Reflux Management System has been approved by the U.S. Food and Drug Administration to treat people with gastroesophageal reflux disease (GERD) who continue to have chronic symptoms, despite taking maximum medication and making recommended lifestyle changes.

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In Older Adults, Extra Fat Tied to Poor Cognitive Function

FRIDAY, March 23 (HealthDay News) -- In older adults (aged 60 to ≤70 years), obesity and high visceral adiposity are associated with poor cognitive function, according to a study published online March 22 in Age and Ageing.

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Drug-Eluting Stents Reduce Risk of Thrombosis

FRIDAY, March 23 (HealthDay News) -- Cobalt-chromium everolimus eluting stents (CoCr-EES) are associated with a significantly lower rate of stent thrombosis within two years of implantation, compared with other bare-metal and drug-eluting stents, according to a meta-analysis published online March 23 in The Lancet.

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Living Donor Age Has Little Impact on Kidney Survival

FRIDAY, March 23 (HealthDay News) -- Living donor age has minimal impact on the survival of a donated kidney, except for those recipients aged 18 to 39 years, according to research published online March 22 in the Clinical Journal of the American Society of Nephrology.

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Aspirin Enhances Platelet Isoprostanes in Type 2 Diabetes

FRIDAY, March 23 (HealthDay News) -- For patients with type 2 diabetes mellitus (T2DM) who are treated with aspirin, isoprostanes are overproduced, which is linked with enhanced platelet recruitment, according to a study published online March 16 in Diabetes.

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Anal HPV, Cancer Common in Men Having Sex With Men

FRIDAY, March 23 (HealthDay News) -- Men who have sex with men (MSM) are at increased risk for anal human papillomavirus (HPV) infection and anal intraepithelial neoplasia (AIN), according to a meta-analysis published online March 23 in The Lancet Oncology.

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Prostaglandin D2 Linked to Hair Loss in Androgenetic Alopecia

FRIDAY, March 23 (HealthDay News) -- Prostaglandin D2 (PGD2) plays a role in inhibition of hair growth in androgenetic alopecia (AGA), according to a study published in the March 21 issue of Science Translational Medicine.

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Thigh Fat Area, Muscle Density Linked to RA Indicators

FRIDAY, March 23 (HealthDay News) -- Thigh fat area and muscle density, but not muscle area, are indicators of disability and physical performance in patients with rheumatoid arthritis (RA), according to a study published online March 5 in Arthritis & Rheumatism.

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Iron Overload Does Not Worsen Stem Cell Transplant Outcomes

FRIDAY, March 23 (HealthDay News) -- Although iron overload before hematopoietic stem cell transplantation (HSCT) is common, iron does not accumulate after transplantation and is not associated with adverse outcomes in patients with leukemia or myelodysplastic syndrome, according to a study published online March 12 in the American Journal of Hematology.

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Antidepressant Use Linked to Pregnancy-Induced HTN

THURSDAY, March 22 (HealthDay News) -- Antidepressant use during pregnancy is associated with an increased risk of pregnancy-induced hypertension, according to a study published online March 21 in the British Journal of Clinical Pharmacology.

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New Guidelines Issued for Acute Bacterial Rhinosinusitis

THURSDAY, March 22 (HealthDay News) -- As the majority of rhinosinusitis cases are viral, antimicrobial therapy should be initiated after establishment of a clinical diagnosis of bacterial rhinosinusitis, and β-lactam agents are recommended for initial therapy, according to the Infectious Diseases Society of America's first rhinosinusitis guidelines published online March 20 in Clinical Infectious Diseases.

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Ibuprofen Cuts Incidence, Severity of Altitude Sickness

THURSDAY, March 22 (HealthDay News) -- For healthy adults ascending from low to high altitude, ibuprofen effectively reduces the incidence and severity of acute mountain sickness, compared with placebo, according to a study published online March 22 in the Annals of Emergency Medicine.

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State Wealth Linked to Markers of Cardiac Health in Women

THURSDAY, March 22 (HealthDay News) -- State-level macro socioeconomic conditions are associated with biomarkers of inflammation, particularly high-sensitivity C-reactive protein (hsCRP), among healthy women, according to a study published online March 20 in BMC Public Health.

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Circulating Endothelial Cells Potential Biomarker for MI

THURSDAY, March 22 (HealthDay News) -- Circulating endothelial cell (CEC) counts are elevated among patients with myocardial infarction (MI), and the cells have distinct morphological features, according to a study published in the March 21 issue of Science Translational Medicine.

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Health Care Team Members Key for Antimicrobial Stewardship

THURSDAY, March 22 (HealthDay News) -- Antimicrobial stewardship programs (ASPs) that use health care epidemiologists (HEs) and infection preventionists (IPs) have a crucial role to play in the effort to combat health care-associated infections (HAIs), including those caused by multidrug-resistant organisms (MDROs), according to the Association for Professionals in Infection Control and Epidemiology and the Society for Healthcare Epidemiology of America position paper published in the March issue of the American Journal of Infection Control.

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Alternative Medicine Alleviates Symptoms of Rhinosinusitis

THURSDAY, March 22 (HealthDay News) -- An integrative East-West medicine (IEWM) approach in addition to standard medical treatment improves symptoms and quality of life (QOL) for patients with chronic rhinosinusitis (CRS), according to a pilot study published in the March issue of the Archives of Otolaryngology -- Head & Neck Surgery.

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Post-Sleep Apnea Surgery Complications Examined

THURSDAY, March 22 (HealthDay News) -- The overall complication rate of multilevel surgery for obstructive sleep apnea (OSA) is 7.1 percent, according to research published online March 19 in the Archives of Otolaryngology -- Head & Neck Surgery.

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Diet Soda Linked to Increase in Glucagon-Like Peptide 1 Levels

THURSDAY, March 22 (HealthDay News) -- Drinking a diet soda before a glucose load is associated with increased glucagon-like peptide 1 (GLP-1) secretion in individuals with type 1 diabetes and healthy controls, but not in those with type 2 diabetes, according to research published online March 12 in Diabetes Care.

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Optimal Prediabetes HbA1c Threshold is 5.7 Percent

THURSDAY, March 22 (HealthDay News) -- Lowering the glycated hemoglobin (HbA1c) cut-off threshold for prediabetes to 5.7 percent is cost-effective even in a high-cost intervention scenario, according to research published online March 13 in the American Journal of Preventive Medicine.

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Cognitive Decline Seen in Elderly After Hospitalization

WEDNESDAY, March 21 (HealthDay News) -- Older people may have an increased risk of memory problems after being discharged from the hospital, according to a study published online March 21 in Neurology.

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REGN727 Monoclonal Antibody Lowers LDL Cholesterol

WEDNESDAY, March 21 (HealthDay News) -- Administration of REGN727, a monoclonal antibody to proprotein convertase subtilisin/kexin 9 (PCSK9), significantly reduces low-density lipoprotein (LDL) cholesterol levels, according to the results of three phase 1 studies published in the March 22 issue of the New England Journal of Medicine.

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Chromosome 12 Mutation Linked to Familial Diarrhea

WEDNESDAY, March 21 (HealthDay News) -- An activating mutation in GUCY2C, encoding guanylate cyclase C (GC-C), is thought to cause a novel familial diarrhea syndrome seen in a Norwegian family, according to a study published online March 21 in the New England Journal of Medicine.

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Tenecteplase Superior to Alteplase for Stroke Treatment

WEDNESDAY, March 21 (HealthDay News) -- Tenecteplase is superior to alteplase for the treatment of acute ischemic stroke for select patients, according to a study published in the March 22 issue of the New England Journal of Medicine.

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Regular Aspirin Use Can Lower Cancer Risk, Studies Confirm

WEDNESDAY, March 21 (HealthDay News) -- Regular aspirin use is associated with a lower long-term risk of colorectal and other, particularly gastrointestinal, cancers as well as a reduced risk of distant metastasis, according to research published online March 21 in The Lancet Oncology.

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Dexmedetomidine Non Inferior for Maintaining Sedation

WEDNESDAY, March 21 (HealthDay News) -- The α2-agonist dexmedetomidine is not inferior to the standard sedatives midazolam or propofol in its ability to maintain light-to-moderate sedation during mechanical ventilation, according to research published in the March 21 issue of the Journal of the American Medical Association.

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Alcohol Effects on Brain Activity Vary With Blackout History

WEDNESDAY, March 21 (HealthDay News) -- A neurobiological mechanism may be associated with alcohol-induced fragmentary blackouts (FBs), with alcohol exerting different effects on neural activity for individuals with or without FBs, according to research published online March 15 in Alcoholism: Clinical and Experimental Research.

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Differences in Interarm BP Linked to Increased Mortality

WEDNESDAY, March 21 (HealthDay News) -- For patients with hypertension, an interarm difference in systolic blood pressure of 10 mm Hg or more or 15 mm Hg or more is associated with an increased risk of cardiovascular events and all-cause mortality over 10 years, according to a study published online March 20 in BMJ.

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Weight Gain Linked to Hot Flashes After Breast Cancer

WEDNESDAY, March 21 (HealthDay News) -- Early-stage breast cancer survivors who gain at least 10 percent of their pre-diagnosis weight are significantly more likely to report hot flashes than those who remain weight stable, according to a study published online March 19 in the Journal of Clinical Oncology.

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Tobacco Smoke Exposure in Childhood Ups COPD Risk

WEDNESDAY, March 21 (HealthDay News) -- Exposure to environmental tobacco smoke (ETS) during childhood is associated with an increased risk of developing chronic obstructive pulmonary disease (COPD) among adult women, and is a significant risk factor for respiratory symptoms in men, according to a study published online Jan. 16 in Respirology.

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Stem Cells Improve Kidney Transplant Outcomes

WEDNESDAY, March 21 (HealthDay News) -- Patients with end-stage renal disease receiving living-related kidney transplants with autologous mesenchymal stem cells (MSCs) instead of antibody induction therapy have improved outcomes, according to a study published in the March 21 issue of the Journal of the American Medical Association.

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Coffee, Caffeine Not Linked to Psoriasis in U.S. Women

WEDNESDAY, March 21 (HealthDay News) -- Coffee and caffeine are not associated with psoriasis incidence after adjustment for smoking, according to a research letter published in the March issue of the Archives of Dermatology.

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Antioxidants Don't Impact Most CSF Biomarkers in Alzheimer's

TUESDAY, March 20 (HealthDay News) -- For patients with mild-to-moderate Alzheimer's disease, antioxidant supplements do not affect cerebrospinal fluid (CSF) biomarkers related to amyloid or tau pathology, according to a study published online March 19 in the Archives of Neurology.

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Anesthesia During Endoscopy, Colonoscopy on the Rise

TUESDAY, March 20 (HealthDay News) -- Use of gastroenterology anesthesia services increased considerably from 2003 to 2009 among both Medicare and commercially-insured patients, according to a study published in the March 21 issue of the Journal of the American Medical Association.

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Survey Describes Docs' Online Professionalism Violations

TUESDAY, March 20 (HealthDay News) -- Most medical licensing authorities receive and act upon reports of physicians' online professionalism violations, according to a research letter published in the March 21 issue of the Journal of the American Medical Association.

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Vitamin E Does Not Reduce Risk of Heart Failure in Women

TUESDAY, March 20 (HealthDay News) -- In a population of healthy women, long-term treatment with vitamin E is not associated with the risk of developing heart failure, according to a study published in the March issue of Circulation: Heart Failure.

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In Out-of-Hospital Cardiac Arrest, Epi Use Linked to Outcomes

TUESDAY, March 20 (HealthDay News) -- Use of epinephrine for resuscitation in patients with out-of-hospital cardiac arrest (OHCA) is associated with increased odds of return of spontaneous circulation, but does not improve patient outcomes, according to a study published in the March 21 issue of the Journal of the American Medical Association.

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Antimicrobial Stewardship Saves Millions of Dollars

TUESDAY, March 20 (HealthDay News) -- Antimicrobial stewardship programs save hospitals millions of dollars, according to a study published in the April issue of Infection Control and Hospital Epidemiology.

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Dapagliflozin Aids Glycemic Control in Type 2 Diabetes

TUESDAY, March 20 (HealthDay News) -- For patients with inadequately controlled type 2 diabetes, treatment with dapagliflozin is associated with improved glycemic control, stabilized insulin dosing, and weight reductions, according to research published in the March 20 issue of the Annals of Internal Medicine.

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Trans Fat Intake Linked to Aggressive Behavior

TUESDAY, March 20 (HealthDay News) -- Consumption of trans fats is associated with greater aggression, according to a study published online March 5 in PLoS One.

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H. Pylori Associated With Impaired Glucose Tolerance

TUESDAY, March 20 (HealthDay News) -- Helicobacter pylori (H. pylori) seropositivity is associated with glycosylated hemoglobin (HbA1c) levels, an interaction which may be augmented by a high body mass index (BMI), according to a study published online March 13 in the Journal of Infectious Diseases.

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Walking Speed Is a Marker for Knee Osteoarthritis

TUESDAY, March 20 (HealthDay News) -- Slower walking speed may be a marker for identifying those at risk for knee osteoarthritis (OA), according to a study published online March 5 in Arthritis Care & Research.

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Bevacizumab Active in HIV-Linked Kaposi's Sarcoma

MONDAY, March 19 (HealthDay News) -- For patients with HIV-associated Kaposi's sarcoma (HIV-KS), bevacizumab is tolerated and induces a response in some patients, according to a study published online March 19 in the Journal of Clinical Oncology.

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Statin Use May Reduce Pneumonia Incidence

MONDAY, March 19 (HealthDay News) -- Treatment with statins, such as rosuvastatin, is associated with a modest reduction in the incidence of pneumonia, according to a study published online March 19 in CMAJ, the journal of the Canadian Medical Association.

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Orthostatic Hypotension Linked to Incident Heart Failure

MONDAY, March 19 (HealthDay News) -- Orthostatic hypotension is associated with incident heart failure, and the association is stronger for those aged 55 years or younger and is slightly reduced by exclusion of individuals with hypertension, according to a study published online March 19 in Hypertension.

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Generic Boniva Approved for Osteoporosis

MONDAY, March 19 (HealthDay News) -- The first generic versions of the once-monthly osteoporosis drug Boniva (ibandronate) have been approved by the U.S. Food and Drug Administration.

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Cardiovascular Health Metrics Reduce Total, Cardio Mortality

MONDAY, March 19 (HealthDay News) -- Meeting a greater number of the seven cardiovascular health metrics from the American Heart Association is associated with a lower risk of all-cause and cardiovascular disease (CVD) mortality, according to a study published online March 16 in the Journal of the American Medical Association.

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Synthetic Cannabinoid Toxicity Among Teenagers on the Rise

MONDAY, March 19 (HealthDay News) -- Smoking synthetic versions of marijuana is landing some teens in the emergency room complaining of restlessness, agitation, and diaphoresis, according to a case report published online March 19 in Pediatrics.

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Study Validates Perimenopausal Memory Complaints

MONDAY, March 19 (HealthDay News) -- For perimenopausal women, memory complaints are associated with working memory and complex attention performance, according to a study published online March 12 in Menopause.

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Ischemic Heart Dise

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