April 2012 Briefing - UrologyLast Updated: May 01, 2012.
Here are what the editors at HealthDay consider to be the most important developments in Urology for April 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Patterns of Brain Activity Tied to Psychogenic Impotence
MONDAY, April 30 (HealthDay News) -- The left superior parietal lobe of the brain is important in the inhibition of sexual response in men with psychogenic erectile dysfunction (ED), according to research published online April 17 in The Journal of Sexual Medicine.
Age, Life Expectancy Influence Termination of PSA Screening
THURSDAY, April 26 (HealthDay News) -- Most primary care providers consider both a man's age and life expectancy in deciding whether to discontinue prostate-specific antigen (PSA) screenings, but multiple factors are involved in this decision, according to a study published online April 19 in Cancer.
USPSTF Guidelines Haven't Changed PSA Screening Practice
TUESDAY, April 24 (HealthDay News) -- Despite the 2008 changes in U.S. Preventive Services Task Force (USPSTF) recommendations against prostate-specific antigen (PSA)-based screening for prostate cancer in men 75 years or older, screening rates remained unchanged for men of all ages between 2005 and 2010, according to a research letter published in the April 25 issue of the Journal of the American Medical Association.
Pathway Involved in Kidney Stone Formation Identified
TUESDAY, April 24 (HealthDay News) -- A gene previously linked to an increased risk of developing kidney stones is part of a calcium-sensitive pathway that regulates calcium absorption in the kidney, according to a study in the April 18 issue of The EMBO Journal.
Bladder Cancer Diagnosis Encourages Smokers to Quit
MONDAY, April 23 (HealthDay News) -- Smokers with a new diagnosis of bladder cancer are significantly more likely to quit compared with smokers in the general population, according to a study published online April 23 in the Journal of Clinical Oncology.
Impaired Fasting Glucose Affects Male Sexual Health
FRIDAY, April 20 (HealthDay News) -- Nearly 20 percent of men with sexual dysfunction have impaired fasting glucose (IFG) and are more likely than men with normal glucose levels to have severe erectile dysfunction (ED), reduced penile blood flow, and overt hypogonadism as well as increased overall cardiovascular (CV) risk, according to a study published online April 10 in The Journal of Sexual Medicine.
CDC: HPV-Associated Cancers Strike More Than 30,000 Yearly
THURSDAY, April 19 (HealthDay News) -- Cancers associated with the human papillomavirus (HPV) are diagnosed in nearly 11 out of 100,000 men and women in the United States annually, and HPV vaccines play an important role in reducing the incidence of those cancers for which screening is not approved, according to a report published in the April 20 issue of the U.S. Centers for Disease Control and Prevention's Morbidity & Mortality Weekly Report.
Chemoradiotherapy Combo Ups Bladder Cancer Control
WEDNESDAY, April 18 (HealthDay News) -- Locoregional control of muscle-invasive bladder cancer is significantly improved with a treatment regimen consisting of radiotherapy and concurrent chemotherapy with mitomycin C and fluorouracil, according to a phase 3 study published in the April 19 issue of the New England Journal of Medicine.
Gender, BMI Impact Bladder Perforation During Resection
MONDAY, April 16 (HealthDay News) -- For patients with bladder tumors, female gender, low body mass index, and tumor characteristics correlate with the risk of bladder perforation during transurethral resection, according to research published in the May issue of The Journal of Urology.
Crizotinib Treatment Lowers Total Testosterone Levels
FRIDAY, April 13 (HealthDay News) -- Men with non-small-cell lung cancer (NSCLC) treated with crizotinib exhibit rapid suppression of total testosterone (T) levels compared with those who do not receive crizotinib treatment, according to research published online April 4 in Cancer.
Herbal Carcinogen Linked to Urothelial Cancer in Taiwan
FRIDAY, April 13 (HealthDay News) -- A carcinogen produced by Aristolochia plants, which are commonly used in herbal remedies in Taiwan, is associated with signature types of DNA damage linked to aristolochic acid in Taiwanese patients with urothelial carcinoma of the upper urinary tract (UUC), according to a study published online April 9 in the Proceedings of the National Academy of Sciences.
Copy Number Variants Tied to Increased Prostate Cancer Risk
THURSDAY, April 12 (HealthDay News) -- Copy number variants (CNVs) of two loci are linked to a significantly higher risk of prostate cancer, according to a study published online April 10 in the Proceedings of the National Academy of Sciences.
BMD Loss Occurs Early in Androgen Deprivation Therapy
WEDNESDAY, April 11 (HealthDay News) -- The highest average change in bone mineral density (BMD) occurs during early treatment of nonmetastatic, hormone-sensitive prostate cancer in men receiving intermittent androgen deprivation therapy (ADT), according to research published online April 9 in the Journal of Clinical Oncology.
Mitochondrial Respiratory Capacity, Sperm Motility Linked
TUESDAY, April 10 (HealthDay News) -- Sperm with higher motility have increased mitochondrial respiratory capacity, according to a study published in the April issue of Urology.
Urinary Incontinence Drugs Have Comparable Efficacy
MONDAY, April 9 (HealthDay News) -- Available pharmacotherapies for treating women with urinary incontinence (UI) produce comparable small benefits, according to research published online April 9 in the Annals of Internal Medicine.
Statins Moderate Effect of Metformin on Prostate Cancer
MONDAY, April 9 (HealthDay News) -- For men with type 2 diabetes treated with metformin, prostate cancer (PCa) incidence varies depending on statin use, with a significantly reduced risk for patients taking a combination of metformin and statins, according to a study published online March 28 in Diabetes Care.
Flavonoid Intake May Protect Men Against Parkinson's
THURSDAY, April 5 (HealthDay News) -- Total flavonoid intake is significantly associated with a lower risk of Parkinson's disease (PD) in men, particularly the intake of anthocyanins and berries, according to a study published online April 4 in Neurology.
Medical Malpractice Claims Incur Substantial Defense Costs
WEDNESDAY, April 4 (HealthDay News) -- Defense costs for medical malpractice claims vary among specialties and are higher for claims that result in indemnity payments, according to a letter published in the April 5 issue of the New England Journal of Medicine.
Fluoroquinolone Use Linked to Retinal Detachment
TUESDAY, April 3 (HealthDay News) -- The use of the oral fluoroquinolone antibiotics is associated with an increased risk of retinal detachment, although the absolute risk is small, according to a study published in the April 4 issue of the Journal of the American Medical Association.
Malodorous Urine Often Reported for Infants With UTI
MONDAY, April 2 (HealthDay News) -- Parental reports of malodorous urine increase the likelihood of a diagnosis of a urinary tract infection (UTI) in young children being evaluated for a suspected infection, according to a study published online April 2 in Pediatrics.