Create Account | Sign In: Author or Forum

 
News  |  Journals  |  Conferences  |  Opinion  |  Articles  |  Forums  |  Twitter    
 
Category: Cardiology | Family Medicine | Geriatrics | Internal Medicine | Emergency Medicine | Nursing | Pharmacy | Conference News

Back to Journal Articles

HRS: Statins Reduce the Risk of A-Fib in Elderly With HTN

Last Updated: May 11, 2012.

 

Statins are particularly effective for patients with CHADS2 score of ≥2, other comorbidities

Share |

Comments: (0)

Tell-a-Friend

 

  Related
 
Elderly patients with hypertension who receive statin therapy have a reduced risk of atrial fibrillation, with statins particularly effective for those with a CHADS2 (congestive heart failure, hypertension, age ≥75 years, diabetes mellitus, prior stroke or transient ischemic attack) score of 2 or more in the presence of other comorbidities, according to a study presented at the annual meeting of the Heart Rhythm Society, held from May 9 to 12 in Boston.

FRIDAY, May 11 (HealthDay News) -- Elderly patients with hypertension who receive statin therapy have a reduced risk of atrial fibrillation (AF), with statins particularly effective for those with a CHADS2 (congestive heart failure, hypertension, age ≥75 years, diabetes mellitus, prior stroke or transient ischemic attack) score of 2 or more in the presence of other comorbidities, according to a study presented at the annual meeting of the Heart Rhythm Society, held from May 9 to 12 in Boston.

To investigate whether comorbidity or CHADS2 score could predict the effectiveness of statin treatment on primary AF prevention, Chen-Ying Hung, M.D., of the Taichung Veterans General Hospital in Taiwan, and colleagues identified 27,002 patients with hypertension, aged 65 years or older, from the National Health Insurance Research Database released by the Taiwan National Health Research Institutes. Statin therapy was received by 8.9 percent of the cohort. The risk of new-onset AF was analyzed according to statin treatment.

During a nine-year follow-up, the researchers identified 2,241 patients who experienced AF. Statin users had a higher prevalence of ischemic heart disease, diabetes, stroke, and chronic renal disease, and were younger than nonusers. Statin therapy was associated with a reduced risk of AF (hazard ratio [HR], 0.81; P = 0.009). The benefit of statins was seen in all patients, irrespective of comorbidity. Statins had a significant effect in patients with a CHADS2 score of ≥2 (HR, 0.69; P < 0.001). This benefit was not seen in patients with hypertension without other comorbidities.

"Statin therapy in elderly patients with hypertension reduces the risk of new-onset AF. Patients with CHADS2 score ≥2 get more benefits from statin use than those with score =1 (hypertension only)," the authors write.

More Information

Copyright © 2012 HealthDay. All rights reserved.


Previous: DNA Methylation Level Is Marker of Breast Cancer Risk Next: Rituximab Little Use in Resistant Idiopathic Nephrotic Syndrome

Reader comments on this article are listed below. Review our comments policy.


Submit your opinion:

Name:

Email:

Location:

URL:

Remember my personal information

Notify me of follow-up comments?

advertisement.gif (61x7 -- 0 bytes)
 

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

Doctors Lounge Membership Application

 
     

 advertisement.gif (61x7 -- 0 bytes)

 

 

Useful Sites
MediLexicon
  Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us
Copyright © 2001-2014
Doctors Lounge.
All rights reserved.

Medical Reference:
Diseases | Symptoms
Drugs | Labs | Procedures
Software | Tutorials

Advertising
Links | Humor
Forum Archive
CME | Conferences

Privacy Statement
Terms & Conditions
Editorial Board
About us | Email

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.