Here are what the editors at HealthDay consider to be the most important developments in Pulmonology for May 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Diabetes Linked to Lung Cancer in Postmenopausal Women
WEDNESDAY, May 30 (HealthDay News) -- Postmenopausal women with diabetes are at a significantly higher risk of developing lung cancer, particularly if they require insulin therapy, according to research published online May 22 in Diabetes Care.
Glucose Levels at Admission Predict Death in Pneumonia
WEDNESDAY, May 30 (HealthDay News) -- For patients with community-acquired pneumonia without preexisting diabetes, serum glucose levels at admission are predictive of death at 28 and 90 days, according to a study published online May 29 in BMJ.
Worse Survival for Recipients of Lungs From Smokers
TUESDAY, May 29 (HealthDay News) -- Recipients of lungs from donors with a positive smoking history have worse three-year survival, but their probability of survival is better than for those who remain on the waiting list, according to a study published online May 29 in The Lancet.
Individual Variation in Antiviral Response Present at Birth
FRIDAY, May 25 (HealthDay News) -- Congenital variations in innate immunity, which are detectable at birth, might predict an infant's susceptibility to acute respiratory tract illness during the first year of life, according to a study published in the May issue of the Journal of Allergy and Clinical Immunology.
Aspirin Effective in Preventing Thromboembolism Recurrence
WEDNESDAY, May 23 (HealthDay News) -- For patients with unprovoked venous thromboembolism who have completed oral anticoagulant treatment, aspirin effectively prevents recurrence, with no apparent increase in the risk of major bleeding, according to a study published in the May 24 issue of the New England Journal of Medicine.
CPAP Use May Reduce Risk of Hypertension in Apnea Patients
TUESDAY, May 22 (HealthDay News) -- For patients with obstructive sleep apnea (OSA) without daytime sleepiness, continuous positive airway pressure (CPAP) does not significantly affect the incidence of hypertension or cardiovascular events; however, regular use of CPAP may reduce the increased risk of incident hypertension seen among patients with OSA, according to two studies published in the May 23/30 issue of the Journal of the American Medical Association.
Chemoradiotherapy Improves Survival for Elderly With NSCLC
TUESDAY, May 22 (HealthDay News) -- For elderly patients with locally advanced non-small-cell lung cancer (NSCLC), treatment with radiotherapy plus carboplatin improves overall survival versus radiotherapy alone, according to a study published May 22 in The Lancet Oncology.
Parents of Children With Epilepsy Have Suboptimal Sleep
MONDAY, May 21 (HealthDay News) -- Parents of children with epilepsy often share a room or cosleep with their child, with both parents and child having suboptimal sleep and greater fatigue, according to a study published online May 17 in Epilepsia.
Outcomes Good for Status Asthmaticus Patients in ICU
WEDNESDAY, May 16 (HealthDay News) -- Although the majority of patients admitted to the intensive care unit (ICU) with status asthmaticus (SA) require mechanical ventilation, the rates of mortality and complications are very low, according to a study published in the March issue of Respiratory Medicine.
Air Pollution Linked to Cardiovascular Disease Markers
TUESDAY, May 15 (HealthDay News) -- Changes in air pollution levels during the Beijing Olympics were associated with changes in biomarkers linked to cardiovascular disease in healthy young people, according to a study published in the May 16 issue of the Journal of the American Medical Association, a theme issue on global health.
Acupuncture Tied to Improved Dyspnea on Exertion in COPD
TUESDAY, May 15 (HealthDay News) -- For patients with chronic obstructive pulmonary disease (COPD), acupuncture appears to improve dyspnea on exertion, according to a study published online May 14 in the Archives of Internal Medicine.
U.S. Lifetime Prevalence of Sleep Walking ~30 Percent
TUESDAY, May 15 (HealthDay News) -- The lifetime prevalence of nocturnal wandering with abnormal state of consciousness (NW) is approximately 30 percent in the U.S. general population, according to a study published in the May 15 issue of Neurology.
African-Americans Have More Severe Sclerosis Complications
FRIDAY, May 11 (HealthDay News) -- African-American patients with systemic sclerosis have more severe complications than Caucasian patients, and these complications are related to the type of autoantibody and severity of lung disease, according to a study published online May 10 in Arthritis & Rheumatism.
Many COPD Comorbidities Independently Tied to Mortality
FRIDAY, May 4 (HealthDay News) -- Twelve comorbidities that include cancer and cardiovascular problems are associated with a higher risk of death in patients with chronic obstructive pulmonary disease (COPD), according to a study published online May 3 in the American Journal of Respiratory and Critical Care Medicine.
CMS Policy Helping Hospitals to Prevent Targeted Infections
FRIDAY, May 4 (HealthDay News) -- Hospitals seem to be paying greater attention to preventing targeted health care-associated infections (HAIs) as a result of the Centers for Medicare and Medicaid Services (CMS) nonpayment policy, according to a study published in the May issue of the American Journal of Infection Control.
Low Vitamin D Linked to Poorer Outcomes in Lung Recipients
THURSDAY, May 3 (HealthDay News) -- For lung transplant recipients, 25-hydroxyvitamin D (25[OH]D) deficiency is associated with increased incidence of acute rejection and infection, and deficiency at one year after transplant is linked with increased mortality, according to a study published online March 5 in The Journal of Heart and Lung Transplantation.
Asthma Has Adverse Effect on Physical Health in Elderly
WEDNESDAY, May 2 (HealthDay News) -- Older adults with asthma have decreased lung function, increased rates of allergic sensitization, and worse quality of life than healthy controls, according to a study published in the May issue of the Annals of Allergy, Asthma & Immunology.
Erlotinib Plus Chemo Doesn't Improve Efficacy in NSCLC
WEDNESDAY, May 2 (HealthDay News) -- Adding chemotherapy with carboplatin plus paclitaxel to the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor erlotinib does not improve efficacy in the treatment of chemotherapy-naive, never or light former smokers with advanced non-small-cell lung cancer (NSCLC), according to a study published online April 30 in the Journal of Clinical Oncology.
Methodological Heterogeneity Seen in Clinical Trials
TUESDAY, May 1 (HealthDay News) -- Clinical studies registered with ClinicalTrials.gov from 2007 and 2010 are predominately small, single-center trials and contain significant heterogeneity in methodology, according to a study published in the May 2 issue of the Journal of the American Medical Association.
Indirect Link ID'd Between Pain Catastrophizing, Severity
TUESDAY, May 1 (HealthDay News) -- Pain catastrophizing, in particular ruminating about pain, has an indirect effect on clinical pain severity and pain-related interference, through sleep disturbance, according to a study published online March 14 in Pain.
Index Identifies Clot Risk in Outpatient Surgery Patients
TUESDAY, May 1 (HealthDay News) -- Using a weighted risk index, the highest-risk outpatient surgery patients have an almost 20-fold increase in risk of venous thromboembolism (VTE) requiring therapy, according to a study published online April 13 in the Annals of Surgery.
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