Create Account | Sign In: Author or Forum

 
News  |  Journals  |  Conferences  |  Opinion  |  Articles  |  Forums  |  Twitter    
 
Category: Cardiology | Family Medicine | Internal Medicine | Nephrology | Journal

Back to Journal Articles

High Future Coronary Event Risk in Chronic Kidney Disease

Last Updated: June 19, 2012.

 

Patients with chronic kidney disease have higher rate of MI than those with diabetes

Share |

Comments: (0)

Tell-a-Friend

 

  Related
 
Patients with chronic kidney disease have higher rates of myocardial infarction than those with diabetes, according to a study published online June 19 in The Lancet.

TUESDAY, June 19 (HealthDay News) -- Patients with chronic kidney disease (CKD) have higher rates of myocardial infarction (MI) than those with diabetes, according to a study published online June 19 in The Lancet.

Marcello Tonelli, M.D., from the University of Alberta in Edmonton, Canada, and colleagues examined whether CKD should be considered as a coronary heart disease risk equivalent using a population-based cohort with measures of estimated glomerular filtration rate (eGFR) and proteinuria. The unadjusted rates and relative rates of MI during follow-up were calculated for five risk groups: individuals with previous MI (with or without diabetes or CKD) and four mutually exclusive groups of those without previous MI classified by the presence or absence of CKD and diabetes.

During a median follow-up of 48 months, the researchers found that 11,340 of 1,268,029 participants were admitted with MI. Individuals with previous MI had the highest unadjusted rate of MI (18.5 per 1,000 person-years). Among individuals without previous MI, the MI rate was lower for those with diabetes, without CKD, than for individuals with CKD, without diabetes (5.4 versus 6.9 per 1,000 person-years). Compared to those with CKD, defined by eGFR of less than 45 mL/min/1.73 m² and severely increased proteinuria, the rate of incident MI was considerably lower for those with diabetes (6.6 versus 12.4 per 1,000 person-years).

"Our findings suggest that chronic kidney disease could be added to the list of criteria defining people at highest risk of future coronary events," the authors write.

Two authors disclosed financial ties to the pharmaceutical industry.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Copyright © 2012 HealthDay. All rights reserved.


Previous: Danger Ubiquity Rationalization Endorsed by Tanning Bed Users Next: Psoriasis Independently Linked to Risk of Type 2 Diabetes

Reader comments on this article are listed below. Review our comments policy.


Submit your opinion:

Name:

Email:

Location:

URL:

Remember my personal information

Notify me of follow-up comments?

advertisement.gif (61x7 -- 0 bytes)
 

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

Doctors Lounge Membership Application

 
     

 advertisement.gif (61x7 -- 0 bytes)

 

 

Useful Sites
MediLexicon
  Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us
Copyright © 2001-2014
Doctors Lounge.
All rights reserved.

Medical Reference:
Diseases | Symptoms
Drugs | Labs | Procedures
Software | Tutorials

Advertising
Links | Humor
Forum Archive
CME | Conferences

Privacy Statement
Terms & Conditions
Editorial Board
About us | Email

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.