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Category: Dermatology | Monthly Briefing

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June 2012 Briefing - Dermatology

Last Updated: July 02, 2012.

 

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Here are what the editors at HealthDay consider to be the most important developments in Dermatology for June 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Hep B Screening Urged Before TNF-Alpha Inhibitor Therapy

FRIDAY, June 29 (HealthDay News) -- All patients with psoriasis should be screened for hepatitis B surface antigen and hepatitis B core antibody prior to the initiation of tumor necrosis factor-alpha inhibitor therapy, according to research published online June 25 in the Journal of the American Academy of Dermatology.

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Impact of Cutaneous Lupus on Quality of Life Evaluated

FRIDAY, June 29 (HealthDay News) -- Cutaneous lupus erythematosus (CLE) similarly negatively impacts quality of life among patients treated at two different centers, according to a study published online June 18 in the British Journal of Dermatology.

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Supreme Court Upholds Health Care Reform Law

THURSDAY, June 28 (HealthDay News) -- The U.S. Supreme Court voted June 28 to uphold the constitutionality of the Patient Protection and Affordable Care Act (PPACA), which has been the subject of debate and multiple lawsuits since its 2010 inception.

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Risk of Second Primary Melanoma Up in Pediatric Patients

THURSDAY, June 28 (HealthDay News) -- Pediatric patients diagnosed with an invasive cutaneous melanoma have nearly double the relative risk of developing a subsequent primary melanoma, compared with adults, according to a study published online June 20 in the British Journal of Dermatology.

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Prenatal Exposure to Butylbenzyl Phthalate Linked to Eczema

WEDNESDAY, June 27 (HealthDay News) -- Prenatal exposure to butylbenzyl phthalate (BBzP), as assessed by increased concentrations of monobenzyl phthalate (MBzP) in the urine, is associated with an increased risk of early-onset eczema in offspring, according to a study published online June 26 in Environmental Health Perspectives.

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Duplicate Payments by Federal Government Increasing

WEDNESDAY, June 27 (HealthDay News) -- The federal government spends a substantial and increasing amount on individuals who are dually enrolled in separate managed care programs (the Veterans Affairs health care system [VA] and Medicare Advantage plan [MA]), according to a study published online June 26 in the Journal of the American Medical Association to coincide with presentation at the Annual Research Meeting of AcademyHealth, held from June 24 to 26 in Orlando, Fla.

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Use of Electronic Records Tied to Fewer Malpractice Claims

TUESDAY, June 26 (HealthDay News) -- Use of electronic health records (EHRs) is associated with fewer medical malpractice claims among physicians from multiple surgical and medical specialties, according to a research letter published online June 25 in the Archives of Internal Medicine.

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Advanced BRAF V600E Melanoma Responds to Dabrafenib

MONDAY, June 25 (HealthDay News) -- Patients with BRAF V600E-mutated metastatic melanoma treated with dabrafenib, an inhibitor of mutated BRAF, have significantly improved progression-free survival compared to those treated with dacarbazine, according to a study published online June 25 in The Lancet.

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Cold-Air Anesthesia Reduces Pain of Laser Treatment

FRIDAY, June 22 (HealthDay News) -- In ablative fractionated carbon-dioxide (CO2) laser treatment for photoaging, cold-air anesthesia used in conjunction with topical anesthesia reduces pain significantly more than topical anesthesia alone, according to research published online June 13 in the Journal of the American Academy of Dermatology.

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Many Psoriasis Patients Undertreated for CV Risk Factors

THURSDAY, June 21 (HealthDay News) -- A large proportion of patients with moderate-to-severe plaque psoriasis are underdiagnosed and undertreated for cardiovascular (CV) risk factors, according to a study published in the July issue of the Journal of the American Academy of Dermatology.

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Half of Residents Report Working While Sick

THURSDAY, June 21 (HealthDay News) -- About half of residents have worked while sick, with many reporting feeling obligated to colleagues and patients, according to a research letter published online June 18 in the Archives of Internal Medicine.

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Accuracy of Melanoma Detection Up in Specialized Clinics

WEDNESDAY, June 20 (HealthDay News) -- From 1998 to 2007, the accuracy of melanoma detection improved in specialized but not non-specialized clinical settings, according to research published in the July issue of the Journal of the American Academy of Dermatology.

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Smoking Increases Risk of Squamous Cell Carcinoma

WEDNESDAY, June 20 (HealthDay News) -- Smoking increases the risk of cutaneous squamous cell carcinoma but is not associated with an increased risk of basal cell carcinoma or nonmelanoma skin cancer, according to a systematic review and meta-analysis published online June 18 in the Archives of Dermatology.

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Tumor-Infiltrating Lymphocyte Grade IDs Melanoma Survival

WEDNESDAY, June 20 (HealthDay News) -- Tumor-infiltrating lymphocyte (TIL) grade is an independent predictor of melanoma-specific survival and sentinel lymph node (SLN) status in patients with localized primary cutaneous melanoma, according to a study published online June 18 in the Journal of Clinical Oncology.

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Psoriasis Independently Linked to Risk of Type 2 Diabetes

TUESDAY, June 19 (HealthDay News) -- Psoriasis is an independent risk factor for the development of type 2 diabetes mellitus, and this risk increases with increasing severity of psoriasis, according to a study published online June 18 in the Archives of Dermatology.

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Danger Ubiquity Rationalization Endorsed by Tanning Bed Users

TUESDAY, June 19 (HealthDay News) -- Despite medical evidence of the potential hazards of tanning beds, current tanning bed users strongly endorse danger ubiquity rationalizations, according to a research letter published in the June issue of the Archives of Dermatology.

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Psoriasis Tied to 14 Other Autoimmune Diseases

FRIDAY, June 15 (HealthDay News) -- Patients with psoriasis have significantly higher odds for having at least one of 14 other autoimmune diseases, according to a study published online June 4 in the Journal of the American Academy of Dermatology.

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CDC: Preventive Health Services Underused Before 2010

THURSDAY, June 14 (HealthDay News) -- Prior to 2010, only about half of all U.S. adults received key preventive health services, according to a report published in the June 15 supplement of the U.S. Centers for Disease Control and Prevention's Morbidity & Mortality Weekly Report.

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New Peri-Op Approach Accurately IDs Melanoma in Nail Matrix

THURSDAY, June 14 (HealthDay News) -- Intraoperative reflectance confocal microscopy (RCM) can be used to diagnose melanonychia striata in the nail matrix, according to a study published online June 7 in the British Journal of Dermatology.

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Gender Gap Exists in Physician Researchers' Salaries

TUESDAY, June 12 (HealthDay News) -- A survey of mid-career academic physician researchers shows that gender differences in salary exist even after adjusting for differences in specialty, institutional characteristics, academic productivity, academic rank, and work hours, according to a study published in the June 13 issue of the Journal of the American Medical Association.

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Vismodegib Has Antitumor Activity in Basal Cell Carcinoma

WEDNESDAY, June 6 (HealthDay News) -- A small-molecule inhibitor of the hedgehog pathway, vismodegib, is associated with tumor response in patients with metastatic or locally advanced basal cell carcinoma (BCC); and vismodegib is efficacious for preventing and treating BCCs in patients with basal cell nevus syndrome, according to two studies published in the June 7 issue of the New England Journal of Medicine.

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Procedure Restores Pigmentation for Patients With Vitiligo

WEDNESDAY, June 6 (HealthDay News) -- The melanocyte-keratinocyte transplantation procedure (MKTP) is well tolerated and is effective for restoring skin pigmentation for some patients with vitiligo, according to a study published in the May issue of the Journal of the American Academy of Dermatology.

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Head Lice Beginning to Show Permethrin Resistance

TUESDAY, June 5 (HealthDay News) -- Although live head lice obtained from school-aged children in Paris remain susceptible to the insecticide malathion, approximately 14 percent have been found to be resistant to permethrin, suggesting a strong basis for future insecticide resistance, according to research published online May 24 in the Journal of the American Academy of Dermatology.

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Basal Cell Carcinoma Response Affected by Past + Recent Stress

MONDAY, June 4 (HealthDay News) -- For patients with basal cell carcinoma (BCC), parental emotional maltreatment combined with a severe life event in the past year correlates with poor immune response to the BCC tumor, according to a study published in the June issue of the Archives of General Psychiatry.

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