June 2012 Briefing - HIV & AIDSLast Updated: July 02, 2012.
Here are what the editors at HealthDay consider to be the most important developments in HIV & AIDS for June 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
New Single Tablet for HIV Is Integrase Inhibitor Based
FRIDAY, June 29 (HealthDay News) -- For treatment-naive patients with HIV-1 infection, the once-daily tablet with HIV integrase strand transfer inhibitor elvitegravir (EVG), co-formulated with the CYP3A4 inhibitor cobicistat (COBI), emtricitabine (FTC), and tenofovir disoproxil fumarate (TDF), also known as EVG/COBI/FTC/TDF, is noninferior to a ritonavir-boosted (RTV) protease inhibitor regimen of atazanavir (ATV)/RTV+FTC/TDF, according to a phase 3 study published online June 29 in The Lancet.
Supreme Court Upholds Health Care Reform Law
THURSDAY, June 28 (HealthDay News) -- The U.S. Supreme Court voted June 28 to uphold the constitutionality of the Patient Protection and Affordable Care Act (PPACA), which has been the subject of debate and multiple lawsuits since its 2010 inception.
Bacterial Vaginosis Linked to Increased HIV-1 Transmission
WEDNESDAY, June 27 (HealthDay News) -- Bacterial vaginosis is associated with a three-fold higher risk of HIV-1 transmission from infected women to their uninfected male partners, according to a study published online June 26 in PLoS Medicine.
Duplicate Payments by Federal Government Increasing
WEDNESDAY, June 27 (HealthDay News) -- The federal government spends a substantial and increasing amount on individuals who are dually enrolled in separate managed care programs (the Veterans Affairs health care system [VA] and Medicare Advantage plan [MA]), according to a study published online June 26 in the Journal of the American Medical Association to coincide with presentation at the Annual Research Meeting of AcademyHealth, held from June 24 to 26 in Orlando, Fla.
Use of Electronic Records Tied to Fewer Malpractice Claims
TUESDAY, June 26 (HealthDay News) -- Use of electronic health records (EHRs) is associated with fewer medical malpractice claims among physicians from multiple surgical and medical specialties, according to a research letter published online June 25 in the Archives of Internal Medicine.
Low Bone Mass for Young Men on Antiretrovirals for HIV
FRIDAY, June 22 (HealthDay News) -- Young men recently diagnosed with HIV infection, treated with antiretroviral therapy (ART), have lower bone mass, according to a study published online May 9 in Clinical Infectious Diseases.
Half of Residents Report Working While Sick
THURSDAY, June 21 (HealthDay News) -- About half of residents have worked while sick, with many reporting feeling obligated to colleagues and patients, according to a research letter published online June 18 in the Archives of Internal Medicine.
Multi-Drug Regimens Cut HIV Transmission Versus Zidovudine
WEDNESDAY, June 20 (HealthDay News) -- For infants of mothers with HIV who did not receive antenatal antiretroviral therapy (ART), treatment with two or three drugs reduces transmission compared with zidovudine alone; and more infants treated with nevirapine together with zidovudine and lamivudine have virologic failure by six months, according to two studies published in the June 21 issue of the New England Journal of Medicine.
CDC: Preventive Health Services Underused Before 2010
THURSDAY, June 14 (HealthDay News) -- Prior to 2010, only about half of all U.S. adults received key preventive health services, according to a report published in the June 15 supplement of the U.S. Centers for Disease Control and Prevention's Morbidity & Mortality Weekly Report.
T Cell Receptor 'Clonotypes' Key to HIV-1 Infection Control
WEDNESDAY, June 13 (HealthDay News) -- The association of particular human leukocyte antigens (HLAs) with the ability of some individuals to control HIV-1 infection is modulated by clones of T cell antigen receptors (TCRs) with specific phenotypes (clonotypes), according to a study published online June 10 in Nature Immunology.
Gender Gap Exists in Physician Researchers' Salaries
TUESDAY, June 12 (HealthDay News) -- A survey of mid-career academic physician researchers shows that gender differences in salary exist even after adjusting for differences in specialty, institutional characteristics, academic productivity, academic rank, and work hours, according to a study published in the June 13 issue of the Journal of the American Medical Association.
Racial Gap in Life Expectancy Down From 2003 to 2008
WEDNESDAY, June 6 (HealthDay News) -- From 2003 to 2008, the gap in life expectancy between non-Hispanic blacks and whites in the United States decreased by about one year for both men and women, according to a research letter published in the June 6 issue of the Journal of the American Medical Association.