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Category: Neurology | Monthly Briefing

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June 2012 Briefing - Neurology

Last Updated: July 02, 2012.

 

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Here are what the editors at HealthDay consider to be the most important developments in Neurology for June 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Supreme Court Upholds Health Care Reform Law

THURSDAY, June 28 (HealthDay News) -- The U.S. Supreme Court voted June 28 to uphold the constitutionality of the Patient Protection and Affordable Care Act (PPACA), which has been the subject of debate and multiple lawsuits since its 2010 inception.

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Risk of Rupture Increases With Size of Cerebral Aneurysm

THURSDAY, June 28 (HealthDay News) -- The natural course of unruptured cerebral aneurysms varies according to their size, location, and shape, according to a study published in the June 28 issue of the New England Journal of Medicine.

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Environmental Risks ID'd for REM Sleep Behavior Disorder

WEDNESDAY, June 27 (HealthDay News) -- Smoking, head injury, pesticide exposure, and farming are potential environmental and lifestyle risk factors for developing idiopathic REM sleep behavior disorder (RBD), according to research published online June 27 in Neurology.

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Long-Term Adverse Cardiac Outcomes for Low-Carb Diets

WEDNESDAY, June 27 (HealthDay News) -- Women who follow low carbohydrate-high protein diets have an increased risk of cardiovascular disease, according to a study published online June 26 in BMJ.

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Oxytocin Levels Linked to Behavior in Williams Syndrome

WEDNESDAY, June 27 (HealthDay News) -- In patients with Williams Syndrome, which is characterized by a deletion of nearly 30 genes and altered social behaviors, levels of the neuropeptide oxytocin are associated with the altered behaviors, according to a study published online June 12 in PLoS One.

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Specific Solvents May Increase Risk of Parkinson's Disease

WEDNESDAY, June 27 (HealthDay News) -- Exposure to specific solvents is associated with an increased risk of Parkinson's disease, according to a study published in the June issue of the Annals of Neurology.

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iPad May Alter Programmable Shunt Valve Settings

WEDNESDAY, June 27 (HealthDay News) -- Exposure to a tablet device may result in a change to programmable shunt valve settings when the tablet is very close to the valve, according to a study published online June 26 in the Journal of Neurosurgery: Pediatrics.

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Duplicate Payments by Federal Government Increasing

WEDNESDAY, June 27 (HealthDay News) -- The federal government spends a substantial and increasing amount on individuals who are dually enrolled in separate managed care programs (the Veterans Affairs health care system [VA] and Medicare Advantage plan [MA]), according to a study published online June 26 in the Journal of the American Medical Association to coincide with presentation at the Annual Research Meeting of AcademyHealth, held from June 24 to 26 in Orlando, Fla.

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Warfarin Safe After Ischemic Stroke in tPA-Treated Patients

TUESDAY, June 26 (HealthDay News) -- For patients receiving tissue plasminogen activator (tPA) after ischemic stroke, warfarin has no effect on the risk of symptomatic intracranial hemorrhage (sICH), according to a study published in the June 27 issue of the Journal of the American Medical Association.

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Use of Electronic Records Tied to Fewer Malpractice Claims

TUESDAY, June 26 (HealthDay News) -- Use of electronic health records (EHRs) is associated with fewer medical malpractice claims among physicians from multiple surgical and medical specialties, according to a research letter published online June 25 in the Archives of Internal Medicine.

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Sleep Benefit Seen in Almost Half of Patients With Parkinson's

TUESDAY, June 26 (HealthDay News) -- Close to half of patients with Parkinson's disease may experience improved motor functioning upon awakening (sleep benefit), according to a study published online May 24 in the Journal of Parkinson's Disease.

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Cannabis Use for Fibromyalgia Linked to Poor Mental Health

FRIDAY, June 22 (HealthDay News) -- More than 10 percent of patients with a diagnosis of fibromyalgia report using marijuana to relieve pain, and those who do so are more likely to be in poorer mental health, seek drugs, and be unemployed, according to a study published online June 21 in Arthritis Care & Research.

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Sleep Apnea Linked to Diabetic Peripheral Neuropathy

THURSDAY, June 21 (HealthDay News) -- Obstructive sleep apnea (OSA) is independently associated with diabetic peripheral neuropathy, even after adjustment for potential confounders, according to a study published online June 21 in the American Journal of Respiratory and Critical Care Medicine.

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Half of Residents Report Working While Sick

THURSDAY, June 21 (HealthDay News) -- About half of residents have worked while sick, with many reporting feeling obligated to colleagues and patients, according to a research letter published online June 18 in the Archives of Internal Medicine.

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Diabetes Linked to Cognitive Decline in Older Adults

THURSDAY, June 21 (HealthDay News) -- Diabetes mellitus (DM) is associated with worse cognitive function and greater cognitive decline among older adults, according to a study published online June 18 in the Archives of Neurology.

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Deep Brain Stimulation Aids Motor Function in Parkinson's

THURSDAY, June 21 (HealthDay News) -- The globus pallidus interna (GPi) and subthalamic nucleus (STN) are both viable deep brain stimulation (DBS) targets for the treatment of motor symptoms in patients with Parkinson's disease, providing stable improvements over 36 months, according to a study published online June 20 in Neurology.

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Poor Outcomes for Hospitalized Patients With Alzheimer's

MONDAY, June 18 (HealthDay News) -- Hospitalization of patients with Alzheimer's disease (AD) is associated with increased risks of death and institutionalization, with the risk further increased for hospitalized patients with delirium, according to a study published in the June 19 issue of the Annals of Internal Medicine.

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Psychological Distress Increases Cerebrovascular Death Risk

MONDAY, June 18 (HealthDay News) -- Psychological distress, as assessed using the 12-item General Health Questionnaire (GHQ-12), is associated with an increased risk of death due to cerebrovascular disease and ischemic heart disease, according to a study published online June 18 in CMAJ, the journal of the Canadian Medical Association.

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Genetic Variants Predict Outcomes After t-PA Treatment

MONDAY, June 18 (HealthDay News) -- Two genetic variants have been identified that are associated with hemorrhagic transformation (HT) and mortality rates after infusion of tissue plasminogen activator (t-PA) in patients with acute ischemic stroke, according to research published online June 9 in the Annals of Neurology.

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Roseola Virus Associated With Febrile Status Epilepticus

FRIDAY, June 15 (HealthDay News) -- The roseola virus, human herpesvirus (HHV)-6B and HHV-7, is associated with febrile status epilepticus (FSE), with HHV infection seen in approximately one-third of FSE cases in young children, according to a study published online June 14 in Epilepsia.

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Simple, Noninvasive Eye Test May Identify Risk for Stroke

FRIDAY, June 15 (HealthDay News) -- An eye test measuring ocular pulse amplitude (OPA) can be performed by ophthalmologists to detect severe carotid artery stenosis (CAS), a known risk factor for stroke, according to a study published in the June issue of Ophthalmology.

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Brain Volume Linked to Walking Outcomes in Diabetes

THURSDAY, June 14 (HealthDay News) -- Gray matter volume is associated with walking outcomes, including speed, stride duration variability, and double support time, in individuals with diabetes, with a stronger correlation seen for those with diabetic peripheral neuropathy (DPN), according to a study published online June 4 in Diabetes Care.

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Cognitive Benefit of Omega-3s in Older Adults Questioned

THURSDAY, June 14 (HealthDay News) -- Omega-3 long-chain polyunsaturated fatty acids (PUFA) supplementation has no benefit on cognitive function in cognitively healthy older people, according to a review published online June 13 in The Cochrane Library.

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Trend Shows Early Menopause Linked to Cerebral Aneurysm

THURSDAY, June 14 (HealthDay News) -- Younger age of menopause is associated with a trend toward an increased likelihood of cerebral aneurysm, according to a study published online June 13 in the Journal of NeuroInterventional Surgery.

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Female APOE ε4 Carriers Have Preclinical Signs of Alzheimer's

THURSDAY, June 14 (HealthDay News) -- Healthy elderly women carrying the apolipoprotein E type 4 allele (APOE ε4) show changes in the brain's memory network characteristic of Alzheimer's disease, which can be observed before any symptoms appear, according to a study published in the June 13 issue of The Journal of Neuroscience.

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In Vitro Fertilization Linked to Multiple Sclerosis Relapse

WEDNESDAY, June 13 (HealthDay News) -- Women with multiple sclerosis (MS) who undergo in vitro fertilization (IVF) are at greater risk of relapse after treatment, particularly if they receive gonadotrophin releasing hormone (GnRH) agonists or if IVF fails, according to a study published online June 11 in the Journal of Neurology, Neurosurgery & Psychiatry.

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Cerebral Damage Key Risk for Visual Impairment in Preemies

WEDNESDAY, June 13 (HealthDay News) -- Cerebral damage and retinopathy of prematurity (ROP) are both independent risk factors for visual impairment in preschool children who were born extremely premature, with cerebral damage being the primary risk factor, according to a study published online June 11 in the Archives of Ophthalmology.

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Life-Long Rx Not Always Needed for Juvenile Myoclonic Epilepsy

WEDNESDAY, June 13 (HealthDay News) -- Juvenile myoclonic epilepsy (JME) is a heterogeneous epilepsy syndrome and life-long antiepileptic drug (AED) treatment is not required in all patients to maintain seizure freedom, according to a study published online June 12 in Epilepsia.

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Gender Gap Exists in Physician Researchers' Salaries

TUESDAY, June 12 (HealthDay News) -- A survey of mid-career academic physician researchers shows that gender differences in salary exist even after adjusting for differences in specialty, institutional characteristics, academic productivity, academic rank, and work hours, according to a study published in the June 13 issue of the Journal of the American Medical Association.

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Short-Term Meditation Improves Brain Function

TUESDAY, June 12 (HealthDay News) -- Meditating for only a few weeks leads to improved white matter changes in areas of the brain linked to self-regulation, according to a study published online June 11 in the Proceedings of the National Academy of Sciences.

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Fractional Anisotropy Abnormalities ID'd in Mild TBI

TUESDAY, June 12 (HealthDay News) -- Following mild traumatic brain injury (mTBI), diffusion tensor imaging (DTI) reveals abnormalities in white matter fractional anisotropy (FA) indicative of traumatic axonal injury, which vary between patients, according to a study published online June 9 in Brain Imaging and Behavior.

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Hospital Noises Affect Brain Activity, Heart Rate in Patients

TUESDAY, June 12 (HealthDay News) -- Typical hospital noises that frequently disrupt the sleep of hospitalized patients influence both cortical brain activity and increase patient heart rate, potentially having a negative impact on the patient's healing and cardiovascular health, according to research published online June 11 in the Annals of Internal Medicine.

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Susceptibility Loci Identified for Migraine Without Aura

MONDAY, June 11 (HealthDay News) -- Genome-wide association analysis has identified susceptibility loci for migraine without aura, two of which overlap with previously reported migraine loci, according to a study published online June 10 in Nature Genetics.

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Walking Speed May Be Early Marker of Cognitive Impairment

MONDAY, June 11 (HealthDay News) -- For elderly patients, walking speed and its variability may help distinguish individuals with mild cognitive impairment (MCI) from those with normal cognition, according to a study published in the June 12 issue of Neurology.

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Neural Stem Cells Generated Directly From Fibroblasts

FRIDAY, June 8 (HealthDay News) -- Neural stem cells can be generated directly from skin cells by reprogramming with a single factor, according to an experimental study published online June 7 in Cell Stem Cell.

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Antidepressants Affect Emotional Temperament

FRIDAY, June 8 (HealthDay News) -- The effects of antidepressants appear to be due, in part, to their effects on improving patient emotional temperament, according to the results of a literature review published in the June issue of CNS Neurosciences & Therapeutics.

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Prediabetes Linked to Increased Risk of Stroke

FRIDAY, June 8 (HealthDay News) -- Prediabetes may be associated with a higher risk of future stroke if defined as impaired glucose tolerance or a combination of impaired fasting glucose and impaired glucose tolerance, according to a study published online June 7 in BMJ.

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Intranasal Insulin Linked to Reduced Food Intake

THURSDAY, June 7 (HealthDay News) -- Intranasally administered insulin is associated with higher brain energy levels and reduced calorie intake, according to a study published online May 14 in Diabetes.

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Exercise Reduces Neuropathic Pain After Nerve Injury in Rats

WEDNESDAY, June 6 (HealthDay News) -- Rats with nerve injury have less neuropathic pain and cytokine overexpression if they participate in progressive exercise training, according to a study published in the June issue of Anesthesia & Analgesia.

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Racial Gap in Life Expectancy Down From 2003 to 2008

WEDNESDAY, June 6 (HealthDay News) -- From 2003 to 2008, the gap in life expectancy between non-Hispanic blacks and whites in the United States decreased by about one year for both men and women, according to a research letter published in the June 6 issue of the Journal of the American Medical Association.

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Depression Linked to Reduced Temporofrontolimbic Coupling

WEDNESDAY, June 6 (HealthDay News) -- Patients with remitted major depressive disorder (MDD) have reduced guilt-selective temporofrontolimbic coupling between the right superior anterior temporal lobe (ATL) and subgenual cingulate cortex and adjacent septal region (SCSR), a region of interest for biases toward guilt versus indignation, according to a study published online June 4 in the Archives of General Psychiatry.

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Aspirin Ups Risk of Bleeding in All But Diabetes Patients

TUESDAY, June 5 (HealthDay News) -- Aspirin use is associated with an increased risk of major bleeding, while patients with diabetes have a high risk of bleeding, independent of aspirin use, according to a study published in the June 6 issue of the Journal of the American Medical Association.

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Soy-Rich Diet Not Found to Improve Global Cognition

MONDAY, June 4 (HealthDay News) -- Long-term dietary supplementation with isoflavone-rich soy protein does not appear to improve the global cognition of healthy postmenopausal women, according to research published in the June 5 issue of Neurology.

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Ischemic Stroke Risk Higher in Women With A-Fib

FRIDAY, June 1 (HealthDay News) -- Women with atrial fibrillation have a moderately higher risk of ischemic stroke than men, even after accounting for multiple cofactors for stroke, according to a study published online May 31 in BMJ.

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Rats Regain Ability to Walk After Spinal Cord Injury

FRIDAY, June 1 (HealthDay News) -- Rats with spinal cord injury are able to regain locomotion after electrochemical treatment and encouragement of supraspinally mediated movements, in a cortical-dependent manner, according to a study published in the June 1 issue of Science.

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