Create Account | Sign In: Author or Forum

News  |  Journals  |  Conferences  |  Opinion  |  Articles  |  Forums  |  Twitter    
Category: Family Medicine | Internal Medicine | Oncology | Pathology | Pulmonology | Surgery | Journal

Back to Journal Articles

Post-Pneumonectomy, New Lung Growth ID’d in Adult Patient

Last Updated: July 19, 2012.

New lung growth can occur in adult humans, according to a case report published in the July 19 issue of the New England Journal of Medicine.


Young woman who underwent pneumonectomy in 1995 had new lung growth in remaining lung

Share |

Comments: (0)




THURSDAY, July 19 (HealthDay News) -- New lung growth can occur in adult humans, according to a case report published in the July 19 issue of the New England Journal of Medicine.

James P. Butler, Ph.D., from Brigham and Women's Hospital and Harvard Medical School in Boston, and colleagues describe a case of new lung growth in a 33-year-old woman who underwent right-sided pneumonectomy in 1995 for treatment of a lung adenocarcinoma.

The researchers found that, following pneumonectomy, there was an expected abrupt decrease in vital capacity. However, vital capacity unexpectedly increased during the subsequent 15 years. Progressive enlargement of the left lung and an increase in the tissue density was noted on serial computed tomography scans. Overall acinar-airway dimensions seen on magnetic resonance imaging with the use of hyperpolarized helium-3 gas were consistent with an increase in alveolar number, but the alveoli in the growing lung were found to be shallower than in normal lungs.

"Several characteristics of this patient may be relevant to lung growth: her relatively young age at the time of pneumonectomy, the degree of parenchymal hyperexpansion (including post-pneumonectomy syndrome), and her daily exercise program," the authors write. "We hypothesize that, reminiscent of the role of stretch in lung development, cyclic stretch as such may be an important trigger for new lung growth. Regardless of the specific mechanism, the findings in this patient support the concept that new lung growth can occur in adult humans."

Full Text (subscription or payment may be required)

Copyright © 2012 HealthDay. All rights reserved.

Previous: High Serum Ceramides Linked to Increased Alzheimer's Risk Next: Poorer Patient Experience at Safety-Net Hospitals

Reader comments on this article are listed below. Review our comments policy.

Submit your opinion:





Remember my personal information

Notify me of follow-up comments?


Useful Sites
  Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us
Copyright © 2001-2016
Doctors Lounge.
All rights reserved.

Medical Reference:
Diseases | Symptoms
Drugs | Labs | Procedures
Software | Tutorials

Links | Humor
Forum Archive
CME | Conferences

Privacy Statement
Terms & Conditions
Editorial Board
About us | Email

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.