Create Account | Sign In: Author or Forum

News  |  Journals  |  Conferences  |  Opinion  |  Articles  |  Forums  |  Twitter    
Category: Oncology | Orthopedics | Surgery | Journal

Back to Journal Articles

Curettage Alone Not Advised for Sacral Giant Cell Tumors

Last Updated: July 25, 2012.

For patients with sacral giant cell tumors, curettage alone is not recommended for surgical management, according to a study published online July 16 in The Spine Journal.


Rate of recurrence significantly lower with marginal excision versus curettage alone

Share |

Comments: (0)




WEDNESDAY, July 25 (HealthDay News) -- For patients with sacral giant cell tumors (GCTs), curettage alone is not recommended for surgical management, according to a study published online July 16 in The Spine Journal.

To develop an optimal treatment strategy for GCTs, Guodong Li, M.D., from the Tongji University School of Medicine in Shanghai, and colleagues reviewed a case series of 32 patients (18 women and 14 men) with sacral GCTs who underwent surgery between August 1996 and August 2008.

The researchers found that the patients underwent either wide resection, marginal resection, marginal resection plus curettage, or curettage alone (two, 11, 12, and seven patients, respectively). The highest and lowest amount of blood loss was seen for the curettage and wide resection groups, respectively. During a median of 42 months of follow-up, local recurrence was noted in 12 patients, including five of seven in the curettage group. The rate of recurrence was significantly lower in the marginal excision group versus the curettage group (18.2 versus 71.4 percent; P = 0.049). Of all the patients, bladder and bowel dysfunction were seen in five and two patients, respectively, while lower limb dysfunction was noted for four patients who underwent marginal resection. The overall and two-year recurrence-free survival was 93.6 and 84.4 percent, respectively.

"Choosing an optimal surgical margin in the treatment of sacral GCTs is of great importance for local recurrence control and sacral nerve root preservation," the authors conclude. "Curettage alone should not be used to treat sacral GCTs."

Full Text (subscription or payment may be required)

Copyright © 2012 HealthDay. All rights reserved.

Previous: Forefoot Joints Don't Improve 28-Joint Count Measurement Next: Pramlintide Improves Glucose Control in Type 1 Diabetes

Reader comments on this article are listed below. Review our comments policy.

Submit your opinion:





Remember my personal information

Notify me of follow-up comments?


Useful Sites
  Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us
Copyright © 2001-2016
Doctors Lounge.
All rights reserved.

Medical Reference:
Diseases | Symptoms
Drugs | Labs | Procedures
Software | Tutorials

Links | Humor
Forum Archive
CME | Conferences

Privacy Statement
Terms & Conditions
Editorial Board
About us | Email

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.