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Category: Endocrinology | Monthly Briefing

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July 2012 Briefing - Diabetes & Endocrinology

Last Updated: August 01, 2012.

 

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Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for July 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Pre-Op Statin Use Ups Insulin Resistance in Heart Surgery

TUESDAY, July 31 (HealthDay News) -- Patients without diabetes who are taking statins prior to cardiac surgery experience increased insulin resistance compared with those not taking statins, according to a study published online July 24 in Diabetes Care.

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Task Force Still Recommends Against Routine ECG Screening

TUESDAY, July 31 (HealthDay News) -- In an update of the 2004 recommendations, the U.S. Preventive Services Task Force (USPSTF) continues to recommend against routine use of electrocardiogram (ECG) screening of asymptomatic adults for coronary heart disease (CHD), according to a scientific statement published online July 31 in the Annals of Internal Medicine.

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No Link Between Telomere Length and Diabetes Risk

TUESDAY, July 31 (HealthDay News) -- Leukocyte telomere length is not independently associated with type 2 diabetes risk in postmenopausal women, according to a study published online July 24 in Diabetes.

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Women With Diabetes Report Low Sexual Satisfaction

MONDAY, July 30 (HealthDay News) -- Women with diabetes are more likely than those without diabetes to report low overall sexual satisfaction, with insulin-treated women at higher risk for problems such as lubrication and orgasm, according to a study published in the August issue of Obstetrics & Gynecology.

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Good Long-Term Limb Salvage for Diabetic Foot Patients

FRIDAY, July 27 (HealthDay News) -- For patients with diabetic foot ulcers (DFUs), long-term limb salvage is favorable; however, long-term survival remains poor, particularly for those with peripheral artery disease (PAD) or chronic renal insufficiency, according to a study published online July 18 in Diabetes Care.

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Racial Disparity in Diabetes Mostly Due to Lifestyle

FRIDAY, July 27 (HealthDay News) -- For postmenopausal women there are large racial/ethnic differences in diabetes incidence, but these are mostly attributable to lifestyle factors, according to a study published online July 25 in Diabetes Care.

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Brain Glucose in Steady-State During Hypoglycemia

THURSDAY, July 26 (HealthDay News) -- The plasma-to-brain glucose relationship and the calculations demonstrating glucose transport over the blood-brain barrier do not differ between healthy subjects and patients with uncomplicated, reasonably well-controlled type 1 diabetes mellitus (T1DM), according to a study published in the August issue of Diabetes.

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Excess Maternal Iodine Linked to Congenital Hypothyroidism

THURSDAY, July 26 (HealthDay News) -- Excess maternal iodine supplementation can result in congenital hypothyroidism, according to a study published online July 26 in The Journal of Pediatrics.

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Pramlintide Improves Glucose Control in Type 1 Diabetes

WEDNESDAY, July 25 (HealthDay News) -- The addition of pramlintide, an analog of the naturally-occurring β-cell peptide amylin, before meals improves blood glucose control in patients with type 1 diabetes receiving insulin through an external closed-loop artificial pancreas system, according to a study published online June 18 in Diabetes Care.

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Two-Thirds of Medicaid Patients Adherent to Chronic Meds

TUESDAY, July 24 (HealthDay News) -- Based on a Medicaid claims model, among New York City (NYC) Medicaid participants, adherence to chronic medications is inadequate, with considerable racial disparities noted, according to a study published online June 22 in the Journal of Urban Health.

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Lipid Storage Protein Linked to Insulin Sensitivity

TUESDAY, July 24 (HealthDay News) -- Perilipin 2 (PLIN2) plays a role in regulating lipid storage in skeletal muscle and can improve insulin sensitivity, according to a study published online July 17 in Diabetes.

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Many Adults With Diabetes Have No Insurance Coverage

MONDAY, July 23 (HealthDay News) -- Approximately two million adults under the age of 65 years with diabetes have no health insurance, according to research published online July 11 in Diabetes Care.

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Adoption of New Screening Guidelines Ups GDM Diagnosis

FRIDAY, July 20 (HealthDay News) -- Implementation of the International Association of Diabetes in Pregnancy Study Group (IADPSG) recommendations for gestational diabetes mellitus (GDM) screening in Israel would increase GDM diagnoses by approximately 50 percent, with risk stratification recommended to reduce over-treatment, according to research published online July 11 in Diabetes Care.

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Drop in Children's Milk Intake Not Tied to Sweet Drink Intake

THURSDAY, July 19 (HealthDay News) -- Decreased milk consumption in children from fifth grade to eighth grade is not associated with changes in sweetened-beverage consumption, according to a study published online July 18 in the Journal of the Academy of Nutrition and Dietetics.

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Higher Phthalate Levels Linked to Diabetes Risk in Women

THURSDAY, July 19 (HealthDay News) -- Urinary levels of several phthalates are associated with an increased odds of diabetes in women, according to a study published online July 13 in Environmental Health Perspectives.

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Most Doctors Satisfied With Electronic Health Records

THURSDAY, July 19 (HealthDay News) -- Although only 55 percent of physicians had adopted electronic health records (EHRs) in 2011, most are somewhat or very satisfied with their system and most report enhanced patient care, according to a July data brief issued by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

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Poorer Patient Experience at Safety-Net Hospitals

THURSDAY, July 19 (HealthDay News) -- Safety-net hospitals (SNHs) perform worse on nearly every measure of patient experience, according to a study published online July 16 in the Archives of Internal Medicine.

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~12,000 Preventable Deaths in English Hospitals Annually

THURSDAY, July 19 (HealthDay News) -- Approximately 12,000 hospital deaths in England each year are preventable, according to research published online July 7 in BMJ Quality & Safety.

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Another New Weight-Loss Drug Approved

WEDNESDAY, July 18 (HealthDay News) -- Qsymia (phentermine and topiramate extended-release) has been approved by the U.S. Food and Drug Administration, making it the second weight-loss drug to be given the agency's green light in less than a month.

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Physical Inactivity Accounts for Considerable Disease Burden

WEDNESDAY, July 18 (HealthDay News) -- Physical inactivity has a considerable impact on the burden of major non-communicable diseases, and causes 9 percent of premature mortality worldwide, according to a study published online July 18 in The Lancet.

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Mortality Risk Up for Fast-Walking Elderly With High BP

WEDNESDAY, July 18 (HealthDay News) -- Among elderly adults, the correlation between blood pressure (BP) and mortality varies with walking speed, according to research published online July 16 in the Archives of Internal Medicine.

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Bariatric Surgery Does Not Reduce Health Care Expenses

WEDNESDAY, July 18 (HealthDay News) -- In a group of older men with substantial disease burden, bariatric surgery is not associated with reduced health care expenditures within three years of surgery, according to research published in the July issue of the Archives of Surgery.

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Obesity Linked to Economic Status in Developing Countries

WEDNESDAY, July 18 (HealthDay News) -- In low- and middle-income developing countries, socioeconomic status (SES) plays an important role in the development of obesity, particularly in women, according to research published online July 5 in Obesity Reviews.

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Social Network Analysis IDs Informal Physician Networks

TUESDAY, July 17 (HealthDay News) -- Informal networks among physicians who share patients demonstrate substantial geographic variability, while within networks, physician and patient characteristics are similar, according to a study published in the July 18 issue of the Journal of the American Medical Association.

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Physical Abuse Doubles Risk of Metabolic Syndrome in Women

TUESDAY, July 17 (HealthDay News) -- After adjusting for age, ethnicity, and menopausal status, a history of childhood physical abuse more than doubles a woman's risk of developing metabolic syndrome during midlife, according to research published online July 9 in Health Psychology.

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NYC Restriction Tied to Lower Trans Fat Content of Fast Food

TUESDAY, July 17 (HealthDay News) -- The introduction of restaurant regulations restricting trans fat use in New York City (NYC) correlated with a significant decrease in the trans fat content of fast food purchases, according to a study published in the July 17 issue of the Annals of Internal Medicine.

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Prevalence of Gout Increases With Increasing BMI

TUESDAY, July 17 (HealthDay News) -- Having an increased body mass index (BMI) correlates with increased prevalence of gout in adults, according to study published online July 6 in Arthritis Care & Research.

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Endurance Training Cuts Lipid-Induced Insulin Resistance

MONDAY, July 16 (HealthDay News) -- Endurance training seems to lessen the effect of lipid-induced insulin resistance, specifically by preventing lipid-induced reduction in nonoxidative glucose disposal (NOGD), according to a study published online July 10 in Diabetes.

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Playing Team Sports Can Reduce Teen Obesity by ~25 Percent

MONDAY, July 16 (HealthDay News) -- High school students who play at least two team sports or walk or bike to school several days a week are less likely to be obese, according to a study published online July 16 in Pediatrics.

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Using a Pedometer Ups Leisure Walking Time for Older Adults

MONDAY, July 16 (HealthDay News) -- Compared with time-based physical activity goals, using a pedometer to measure steps increases leisure walking time, even a year after the initial intervention, according to a study published in the May/June issue of the Annals of Family Medicine.

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Dietary Self-Monitoring Linked to Greater Weight Loss

MONDAY, July 16 (HealthDay News) -- Dietary self-monitoring in the form of food journal use correlates with improved weight loss, while missing meals and eating out frequently are associated with less weight loss among postmenopausal overweight-to-obese women, according to a study published online July 16 in the Journal of the Academy of Nutrition and Dietetics.

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Hyperfiltration Independent Risk Factor for Diabetic Neuropathy

FRIDAY, July 13 (HealthDay News) -- In patients with type 2 diabetes, persistent glomerular hyperfiltration is associated with nephropathy and greater declines in renal function, according to a study published online July 6 in Diabetes Care.

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Maternal Obesity Linked to Impaired Fetal Iron Transfer

FRIDAY, July 13 (HealthDay News) -- Maternal obesity is associated with impaired iron transfer to the fetus, possibly through upregulation of hepcidin, according to a study published online June 21 in the Journal of Perinatology.

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Vaginal Dilation Outcomes Equivalent to Vaginoplasty

FRIDAY, July 13 (HealthDay News) -- Long-term psychosexual outcomes for patients undergoing vaginal dilation are at least equivalent to those undergoing vaginoplasty, according to a study published in the July issue of The Journal of Sexual Medicine.

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Chemo Combo Promising for Pancreatic Neuroendocrine Tumors

FRIDAY, July 13 (HealthDay News) -- The combination of temozolomide and bevacizumab seems to benefit patients with advanced pancreatic neuroendocrine tumors (NETs), according to a study published online July 9 in the Journal of Clinical Oncology.

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Resistance Exercise Improves Insulin Sensitivity in Obese Boys

THURSDAY, July 12 (HealthDay News) -- Both aerobic and resistance exercise (without calorie restriction) reduce fat and improve fitness in obese adolescent boys, although only resistance exercise improves insulin sensitivity, according to a study published online June 29 in Diabetes.

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Social Influence, Choice of Friends Impact Teen Obesity

THURSDAY, July 12 (HealthDay News) -- Social influence and the tendency to select similar friends both play a role in patterns of obesity among adolescents, according to a study published online June 29 in PLoS One.

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Turmeric Component Reduces Type 2 Diabetes Incidence

THURSDAY, July 12 (HealthDay News) -- A component of turmeric -- curcumin -- reduces the incidence of type 2 diabetes and improves β-cell function in adults with prediabetes, according to a study published online July 6 in Diabetes Care.

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Resistance Training Improves Some Inflammatory Markers

WEDNESDAY, July 11 (HealthDay News) -- Resistance training (RT) can reduce visceral fat and alter levels of certain inflammatory markers, according to research published in the July issue of Obesity Reviews.

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Lower Risk of Adverse Outcomes Seen in Obese With Heart Failure

TUESDAY, July 10 (HealthDay News) -- For both women and men with advanced heart failure, having a high body mass index (BMI) or waist circumference (WC) is associated with a reduced risk of adverse outcomes, according to a study published in the July 1 issue of The American Journal of Cardiology.

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Insulin Delivery, Glucose Monitoring Methods Compared

TUESDAY, July 10 (HealthDay News) -- Continuous subcutaneous insulin infusion (CSII) and multiple daily injections (MDI) offer similar improvements in glycemic control in adults with type 1 diabetes, while the addition of real-time continuous glucose monitoring (rt-CGM) improves glycemic control compared with MDI or self-monitored blood glucose (SMBG), according to a review published online July 10 in the Annals of Internal Medicine.

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Reducing Sedentary Behavior Could Increase Life Expectancy

TUESDAY, July 10 (HealthDay News) -- In the United States, reducing sedentary behaviors, including sitting and television viewing, may result in an increase in life expectancy, according to a study published online July 9 in BMJ Open.

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Top Medical Organizations Support Hormone Replacement

MONDAY, July 9 (HealthDay News) -- Ten years after the Women's Health Initiative (WHI) declared that hormone replacement therapy may do more harm than good in the prevention of chronic disease, the North American Menopause Society (NAMS), the American Society for Reproductive Medicine, and The Endocrine Society have issued a joint statement concluding hormone therapy safe and effective in the treatment of menopausal symptoms.

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Vitamin D Status Impacts Weight Gain in Older Women

MONDAY, July 9 (HealthDay News) -- For older women who gain weight, high levels of 25-hydroxyvitamin D [25(OH)D] are linked with less weight gain compared to that found in women with low levels of 25(OH)D, according to a study published online June 25 in the Journal of Women's Health.

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Nonnutritive Sweetener Role in Cutting Sugar Intake Explored

MONDAY, July 9 (HealthDay News) -- Although the evidence is limited, nonnutritive sweeteners (NNS) have a potential role to play in facilitating reduction of added sugar intake, as long as they do not cause a compensatory increase in energy intake, according to a new scientific statement issued by the American Heart Association and the American Diabetes Association and published online July 9 in Circulation.

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Correlates of Diabetic Foot Complications Identified

FRIDAY, July 6 (HealthDay News) -- For patients with diabetes, increased poly(ADP-ribose) (PAR) immunoreactivity, reduced abundance of type 1 procollagen, and impaired skin structure correlate with foot complications, according to a study published online June 29 in Diabetes Care.

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Obesity Is a Risk Factor for Poor Remission Rates in RA

FRIDAY, July 6 (HealthDay News) -- For patients with long-standing rheumatoid arthritis treated with anti-tumor necrosis factor-α (anti-TNFα) therapies, obesity is related to poor remission rates, according to a study published online June 21 in Arthritis Care & Research.

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Early Intensive Diabetes Therapy Preserves β-Cell Function

FRIDAY, July 6 (HealthDay News) -- Early, intensive therapy for type 2 diabetes with either insulin plus metformin or triple oral therapy preserves β-cell function for at least 3.5 years, according to a study published in the July issue of Diabetes Care.

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Elementary Student Access to High-Calorie Drinks Declining

FRIDAY, July 6 (HealthDay News) -- Trends suggest that public elementary school student access to sugar-sweetened beverages and non-Institute of Medicine (IOM)-approved competitive beverages have declined significantly from 2006-2007 to 2010-2011, according to a research letter published in the July issue of the Archives of Pediatrics & Adolescent Medicine.

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Patient Decision Aid Beneficial in Papillary Thyroid Cancer

THURSDAY, July 5 (HealthDay News) -- Patients with early-stage papillary thyroid cancer (PTC) may benefit from the use of a patient-directed computerized decision aid (DA) to provide medical knowledge and resolve decisional conflicts regarding the use of adjuvant radioactive iodine (RAI) treatment, according to research published online July 2 in the Journal of Clinical Oncology.

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High-Dose Vitamin D 'Somewhat Favorable' in Fracture Prevention

THURSDAY, July 5 (HealthDay News) -- High-dose (≥800 IU daily) vitamin D supplementation is associated with a decreased risk of hip fracture and nonvertebral fractures among older adults, according to a study published in the July 5 issue of the New England Journal of Medicine.

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Limited Evidence Links Pioglitazone to Bladder Cancer

TUESDAY, July 3 (HealthDay News) -- Limited evidence supports an increased risk of bladder cancer in adults with type 2 diabetes treated with thiazolidinediones, specifically pioglitazone, according to a review and meta-analysis published online July 3 in CMAJ, the journal of the Canadian Medical Association.

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Western-Style Fast Food Poses Health Risk to Singaporeans

MONDAY, July 2 (HealthDay News) -- Chinese Singaporeans who frequently consume Western-style fast food items have an increased risk of developing type 2 diabetes mellitus and of coronary heart disease (CHD) mortality, according to a study published online July 2 in Circulation.

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Incretin Effect Independent of Glycemia Level

MONDAY, July 2 (HealthDay News) -- The enhanced insulin secretion after meals mediated by two intestinal hormones, known as the incretin effect, is independent of glycemia in healthy individuals, according to a study published online June 25 in Diabetes.

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