Create Account | Sign In: Author or Forum

 
 
News  |  Journals  |  Conferences  |  Blogs  |  Articles  |  Forums  |  Twitter    
 

 Headlines:

 

Category: Endocrinology | Family Medicine | Gynecology | Nursing | Pediatrics | Journal

Back to Journal Articles

Nutrition Type Affects Endocrinology in SGA Infants

Last Updated: August 01, 2012.

 

Adiponectin and insulin growth factor elevated in formula-fed small-for-gestational-age infants

Share |

Comments: (0)

Tell-a-Friend

 

  Related
 
Small-for-gestational-age (SGA) infants who are formula-fed have elevated endocrine levels of high-molecular-weight adiponectin and insulin growth factor-I compared with breastfed SGA infants, according to research published in the August issue of Diabetes.

WEDNESDAY, Aug. 1 (HealthDay News) -- Small-for-gestational-age (SGA) infants who are formula-fed (FOF) have elevated endocrine levels of high-molecular-weight (HMW) adiponectin and insulin growth factor-I (IGF-I) compared with breastfed (BRF) SGA infants, according to research published in the August issue of Diabetes.

Francis de Zegher, M.D., of the University of Leuven in Belgium, and colleagues conducted a study comparing 72 control infants born appropriate-for-gestational-age with 46 BRF and 56 FOF infants who had been born SGA. FOF infants received either standard formula or protein-rich formula. At birth and at 4 months of age, body composition and HMW adiponectin and IGF-I levels were measured.

In the first four months, the researchers found that the SGA infants catch-up growth was primarily confined to lean mass, regardless of whether the infant was BRF or received formula. SGA-BRF infants had normal HMW adiponectin and IGF-I levels compared with BRF infants born appropriate-for-gestational-age. In contrast, SGA-FOF infants had increased HMW adiponectin (particularly after receiving standard formula) and increased levels of IGF-I (particularly after receiving protein-rich formula).

"In conclusion, neonatal nutrition seems to influence endocrinology more readily than body composition of SGA infants," the authors write. "Follow-up will disclose whether the endocrine abnormalities in SGA-FOF infants can serve as early markers of an unfavorable metabolic course and whether they may contribute to design early interventions that prevent subsequent disease, including diabetes."

Abstract
Full Text (subscription or payment may be required)

Copyright © 2012 HealthDay. All rights reserved.


Previous: July 2012 Briefing - Pharmacy Next: Endoscopic, Open Vein-Graft Harvesting Outcomes Similar

Reader comments on this article are listed below. Review our comments policy.


Submit your opinion:

Name:

Email:

Location:

URL:

Remember my personal information

Notify me of follow-up comments?

advertisement.gif (61x7 -- 0 bytes)
 

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

  • Ask a Doctor Teams: Respond to patient questions and discuss challenging presentations with other members.

Doctors Lounge Membership Application

 
     

 advertisement.gif (61x7 -- 0 bytes)

 

 

Useful Sites
MediLexicon
  Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us
Copyright © 2001-2014
Doctors Lounge.
All rights reserved.

Medical Reference:
Diseases | Symptoms
Drugs | Labs | Procedures
Software | Tutorials

Advertising
Links | Humor
Forum Archive
CME | Conferences

Privacy Statement
Terms & Conditions
Editorial Board
About us | Email

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.