Create Account | Sign In: Author or Forum

News  |  Journals  |  Conferences  |  Opinion  |  Articles  |  Forums  |  Twitter    
Category: Family Medicine | Internal Medicine | Neurology | Nursing | Psychiatry | Journal

Back to Journal Articles

Mild Cognitive Decline in Nearly Half Lacunar Stroke Patients

Last Updated: August 27, 2012.


Mild cognitive impairment also seen in those with minimal or no physical disabilities

Share |

Comments: (0)



Mild cognitive impairment is present in nearly half of patients with lacunar stroke, according to a study published online Aug. 18 in the Annals of Neurology.

MONDAY, Aug. 27 (HealthDay News) -- Mild cognitive impairment (MCI) is present in nearly half of patients with lacunar stroke, according to a study published online Aug. 18 in the Annals of Neurology.

Claudia Jacova, Ph.D., of the University of British Columbia in Vancouver, Canada, and associates conducted a study to characterize, and estimate the prevalence of, neuropsychological impairment in 1,636 English-speaking lacunar stroke patients. Using published norms, raw scores were converted to z scores. Participants underwent neuropsychological testing at baseline and those with impairment (z score of ≤1.5) in memory and/or non-memory domains were classified as having MCI.

The researchers found that the average z scores at baseline testing were below zero. The largest deficits were seen in measures of episodic memory (range of means, −0.65 to −0.92), verbal fluency (mean, −0.89), and motor dexterity (mean, −2.5). Of the participants, 47 percent were classified as having MCI, which included 36 percent amnestic, 37 percent amnestic multidomain, and 28 percent non-amnestic. Forty-one percent of those with Rankin score of 0 to 1 and Barthel score of 100 percent had MCI.

"In this large, well-characterized cohort of lacunar stroke patients, MCI was present in nearly half, including many with minimal or no physical disabilities," the authors write. "Cognitive dysfunction in lacunar stroke patients may commonly be overlooked in clinical practice but may be as important as motor and sensory sequelae."

Study medication was donated by Sanofi/BMS USA.

Full Text (subscription or payment may be required)

Copyright © 2012 HealthDay. All rights reserved.

Previous: Poor Survival for Obese Women With HR+ Breast Cancer Next: Reasoning Training Alters Brain Microstructure

Reader comments on this article are listed below. Review our comments policy.

Submit your opinion:





Remember my personal information

Notify me of follow-up comments?

advertisement.gif (61x7 -- 0 bytes)

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

Doctors Lounge Membership Application


 advertisement.gif (61x7 -- 0 bytes)



Useful Sites
  Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us
Copyright © 2001-2015
Doctors Lounge.
All rights reserved.

Medical Reference:
Diseases | Symptoms
Drugs | Labs | Procedures
Software | Tutorials

Links | Humor
Forum Archive
CME | Conferences

Privacy Statement
Terms & Conditions
Editorial Board
About us | Email

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.