Here are what the editors at HealthDay consider to be the most important developments in Rheumatology for August 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Subclinical Atherosclerosis Noted in Diffuse Scleroderma
WEDNESDAY, Aug. 29 (HealthDay News) -- Patients with diffuse systemic sclerosis (SSc), without any clinical evidence of cardiovascular disease, have indicators of subclinical atherosclerosis, according to a study published online Aug. 16 in Arthritis Care & Research.
Pharmacist-Led Intervention Benefits Knee Osteoarthritis
TUESDAY, Aug. 28 (HealthDay News) -- Community-based pharmacists can initiate a coordinated care strategy to better identify knee osteoarthritis (OA) and improve function, pain, and quality of life, according to a study published online Aug. 28 in Arthritis Care & Research.
Claustrophobia Linked to Depression With Back Pain
FRIDAY, Aug. 24 (HealthDay News) -- Claustrophobia is tied to higher rates of depression and psychological distress, but not disability, in back pain patients, according to a study published in the August issue of the Journal of Spinal Disorders & Techniques.
Multidisciplinary Approach Cuts Symptoms of Fibromyalgia
FRIDAY, Aug. 24 (HealthDay News) -- Multidisciplinary treatment adapted for women with low educational levels is superior to conventional pharmacotherapy in reducing key symptoms of fibromyalgia (FM), including sleep disturbances, catastrophizing, and psychological distress, according to research published online Aug. 16 in Arthritis Care & Research.
Procedure Aids Severe, Rigid Scoliosis in Low-Weight Adults
FRIDAY, Aug. 24 (HealthDay News) -- For patients with severe and rigid scoliosis and low body weight, a two-stage vertebral column resection (VCR) procedure with posterior pedicle screw instrumentation can achieve good correction of scoliosis, according to a study published online Aug. 20 in The Spine Journal.
Muscle-Related Statin Effects Seem to Correlate With Potency
FRIDAY, Aug. 24 (HealthDay News) -- The rates of muscle-related adverse effects (AEs) differ greatly for various statins, with the highest reported rates seen for rosuvastatin, according to research published online Aug. 22 in PLoS One.
Dual Action Antibody Reverses Menopausal Bone Loss
THURSDAY, Aug. 23 (HealthDay News) -- An antibody can reverse bone loss in menopausal mice by both blocking bone breakdown and stimulating bone formation, according to an experimental study published online Aug. 20 in the Proceedings of the National Academy of Sciences.
New Decision Aid for Treatment of Herniated Disc Beneficial
THURSDAY, Aug. 23 (HealthDay News) -- A new patient decision instrument meets the criteria of acceptability, reliability, and validity, and improves the quality of patient decision-making for treatment of a herniated disc, according to a study published in the Aug. 15 issue of Spine.
Low Back Pain Outcomes Not Improved by Early Imaging
WEDNESDAY, Aug. 22 (HealthDay News) -- For workers with low back pain, early magnetic resonance imaging (MRI) is not associated with better health outcomes at one year, according to a study published in the Aug. 15 issue of Spine.
BMI, Post-Exercise Knee Laxity Change Tied to OA Progression
TUESDAY, Aug. 21 (HealthDay News) -- In patients with osteoarthritis (OA) of the knee, changes in knee joint laxity during stair climbing or other repetitive physical activity and baseline body mass index (BMI) are associated with disease progression, according to a study published online Aug. 8 in Arthritis & Rheumatism.
2012 Indicators of Well-Being for Older Americans Issued
MONDAY, Aug. 20 (HealthDay News) -- The estimates of selected indicators for well-being for older Americans for 2012 have been released by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics.
Even Minor Changes in Physical Activity Improve Bone Health
FRIDAY, Aug. 17 (HealthDay News) -- For premenopausal women, physical activity correlates with decreased sclerostin, increased serum insulin-like growth factor-I (s-IGF-I), and increased bone formation markers, according to a study published online Aug. 3 in the Journal of Clinical Endocrinology & Metabolism.
Catastrophizing Doesn't Predict Low Back Pain Evolution
THURSDAY, Aug. 16 (HealthDay News) -- For adult patients with acute or chronic low back pain (LBP), assessing the baseline score for catastrophizing does not help clinicians in routine clinical practice predict the evolution of LBP or the patient's disability at three months, according to a study published online July 23 in The Spine Journal.
Poor Follow-Up of Hospital Tests Often Due to Late Orders
TUESDAY, Aug. 14 (HealthDay News) -- Poor follow-up of test results at or after discharge from the hospital is often due to tests requested on the day of discharge, according to a letter to the editor published online Aug. 13 in the Archives of Internal Medicine.
Staph Superantigen Induces Lupus-Like Features in Mice
MONDAY, Aug. 13 (HealthDay News) -- Chronic exposure to superantigen (SAg)-producing Staphylococcus aureus can induce systemic inflammatory disease symptoms in mice, with features similar to those of systemic lupus erythematosus (SLE), according to a study published online July 13 in The Journal of Immunology.
Periodontal Disease More Likely in Rheumatoid Arthritis
MONDAY, Aug. 13 (HealthDay News) -- Periodontal disease (PD) is significantly more likely among nonsmoking, treatment-naive patients with rheumatoid arthritis (RA) than among healthy controls, according to research published online Aug. 8 in the Annals of the Rheumatic Diseases.
High-Field MRI Superior for Delineation of Alar Ligaments
FRIDAY, Aug. 10 (HealthDay News) -- High-field magnetic resonance imaging (MRI) (1.5 Tesla [T], 3 T) is superior to low-field MRI (1 T) for the delineation of alar ligaments (AL), but the field strength does not influence signal intensity in healthy volunteers, according to a study published in the Aug. 1 issue of Spine.
Good Stability With Artificial Disc Plus Cage Fusion
FRIDAY, Aug. 10 (HealthDay News) -- For patients with multi-level cervical disc herniation, artificial cervical disc replacement and adjacent segment cage fusion achieves definite stabilization and satisfactory mobility, according to research published online July 24 in the Journal of Spinal Disorders & Techniques.
Multifactorial Mechanisms Underlie Leg Weakness in Hip OA
THURSDAY, Aug. 9 (HealthDay News) -- Multiple factors contribute to leg weakness in people with hip osteoarthritis (OA), with muscle atrophy being the strongest contributor, according to the results of a systematic review published online July 25 in Arthritis Care & Research.
Similar Mortality With Different TNF-α Inhibitor Therapies in RA
THURSDAY, Aug. 9 (HealthDay News) -- For patients with rheumatoid arthritis there are no significant differences in the overall mortality risk with different tumor necrosis factor-α inhibitor (TNFi) therapies (adalimumab, etanercept, and infliximab), according to a study published online Aug. 8 in Arthritis & Rheumatism.
Tofacitinib Superior to Placebo for Rheumatoid Arthritis
WEDNESDAY, Aug. 8 (HealthDay News) -- For patients with rheumatoid arthritis, a novel oral Janus kinase inhibitor, tofacitinib, is associated with reduced symptoms when used as monotherapy or in addition to background methotrexate, according to two phase 3 studies published in the Aug. 9 issue of the New England Journal of Medicine.
Infection Risk Up for Seniors With Rheumatoid Arthritis
TUESDAY, Aug. 7 (HealthDay News) -- Elderly adults with rheumatoid arthritis have a considerable risk of serious infection, with antirheumatic drug use increasing the risk, according to a study published online July 25 in Arthritis Care & Research.
Learned Helplessness Linked to Arthritis Disease Outcomes
MONDAY, Aug. 6 (HealthDay News) -- For patients with inflammatory polyarthritis (IP), learned helplessness (LH) correlates with disease outcomes and seems to mediate the association between socioeconomic status (SES) and disease outcomes, according to a study published in the August issue of Arthritis Care & Research.
Thigh Muscle Density Linked to Physical Functioning in RA
FRIDAY, Aug. 3 (HealthDay News) -- Thigh muscle density (TMD), as derived from computed tomography (CT), appears to be a strong indicator of physical functioning and disability in rheumatoid arthritis (RA) patients, according to a study published in the August issue of Arthritis & Rheumatism.
Clinicians Can Unintentionally Prompt Nocebo Effect
THURSDAY, Aug. 2 (HealthDay News) -- The nocebo effect, or induction of a symptom perceived as negative by sham treatment and/or the suggestion of negative expectation, may arise from suggestions by doctors and nurses, according to a study published in Deutsches Ärzteblatt International.
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