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Category: Internal Medicine | Monthly Briefing

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August 2012 Briefing - Internal Medicine

Last Updated: September 04, 2012.

 

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Here are what the editors at HealthDay consider to be the most important developments in Internal Medicine for August 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Advanced-Stage Cancer Patients Often Reluctant to Exercise

FRIDAY, Aug. 31 (HealthDay News) -- For individuals with advanced cancer, reluctance to participate in exercise may be due to symptoms, lack of specific guidance, and lack of recognition of the role of exercise in mitigating symptoms, according to a study published in the July issue of the Journal of Pain and Symptom Management.

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Factors Affecting Life Expectancy for Older Adults Studied

FRIDAY, Aug. 31 (HealthDay News) -- Even for adults aged 75 years and older, keeping up a healthy lifestyle, including physical activity and not smoking, is associated with increased life expectancy, according to a study published online Aug. 30 in BMJ.

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Kidney Stones Increase Risk of Adverse Kidney Outcomes

FRIDAY, Aug. 31 (HealthDay News) -- Kidney stones correlate with an increased risk of adverse kidney outcomes, including end-stage renal disease (ESRD), stage 3b to 5 chronic kidney disease, and sustained doubling of serum creatinine, but increases in absolute rates are small, according to a study published online Aug. 30 in BMJ.

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Even Normal Range Albuminuria Ups Cardiovascular Risk

FRIDAY, Aug. 31 (HealthDay News) -- For patients with type 2 diabetes with normal albumin levels, any degree of albuminuria is associated with an increased risk of cardiovascular events, according to a study published online Aug. 30 in the Journal of the American Society of Nephrology.

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Effective Short-, Long-Term Weight-Loss Strategies Differ

FRIDAY, Aug. 31 (HealthDay News) -- In postmenopausal women, some weight-loss strategies that are successful for the short-term are not effective or sustainable for long-term weight loss, according to a study published in the September issue of the Journal of the Academy of Nutrition and Dietetics.

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Lower Prostate Cancer-Specific Death With Anticoagulant Use

THURSDAY, Aug. 30 (HealthDay News) -- Anticoagulant (AC) therapy, particularly aspirin, is associated with a reduced risk of prostate cancer-specific mortality (PCSM) among men treated with radical prostatectomy (RP) or radiotherapy (RT), according to a study published online Aug. 27 in the Journal of Clinical Oncology.

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Lung Cancer Risk Unaffected by Metformin Use in Diabetes

THURSDAY, Aug. 30 (HealthDay News) -- Patients with type 2 diabetes who take metformin do not have a reduced risk of lung cancer, in contrast to previous observational studies, according to a study published online Aug. 24 in Diabetes Care.

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Similar Rate of CV Events With Atenolol, Metoprolol Tartrate

THURSDAY, Aug. 30 (HealthDay News) -- There are no significant differences in the rates of incident myocardial infarction (MI), heart failure, or stroke for patients with hypertension starting treatment with atenolol or metoprolol tartrate, according to a study published online Aug. 27 in the Archives of Internal Medicine.

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Cognitive Decline Worse for Women vs. Men in Alzheimer's

THURSDAY, Aug. 30 (HealthDay News) -- Women with Alzheimer's disease consistently experience greater cognitive deterioration than men, according to results from a meta-analysis published Aug. 23 in the Journal of Clinical and Experimental Neuropsychology.

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Novel Pathogenic Virus Identified in Missouri

THURSDAY, Aug. 30 (HealthDay News) -- A novel pathogenic virus dubbed the Heartland virus, which is a member of the phlebovirus genus, has been identified in two patients from Missouri, according to a report published in the Aug. 30 issue of the New England Journal of Medicine.

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Resistance to Second-Line TB Drugs Is Common Globally

THURSDAY, Aug. 30 (HealthDay News) -- Nearly half of patients with tuberculosis in eight countries show resistance to at least one second-line drug, with previous treatment with second-line drugs strongly associated with resistance to these drugs and with extensively drug-resistant (XDR) tuberculosis, according to a study published online Aug. 30 in The Lancet.

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Lacunar Stroke Outcomes No Better With Dual Antiplatelets

WEDNESDAY, Aug. 29 (HealthDay News) -- Treating patients with recent lacunar strokes with dual antiplatelet therapy (clopidogrel plus aspirin) is not associated with a reduction in the risk of recurrent stroke, and correlates with significant increases in the risk of major hemorrhage and death, according to research published in the Aug. 30 issue of the New England Journal of Medicine.

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Eating Chocolate May Lower Stroke Risk for Men

WEDNESDAY, Aug. 29 (HealthDay News) -- In men, moderate chocolate consumption on a regular basis may lower the risk of any type of stroke by about 17 to 19 percent, according to research published online Aug. 29 in Neurology.

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No 30-Day Mortality Reduction With Intraaortic Balloon Pump

WEDNESDAY, Aug. 29 (HealthDay News) -- In patients with cardiogenic shock complicating acute myocardial infarction, for whom early revascularization strategy is planned, intraaortic balloon counterpulsation does not significantly lower 30-day mortality, according to a study published online Aug. 27 in the New England Journal of Medicine to coincide with presentation at the annual European Society of Cardiology Congress, held from Aug. 25 to 29 in Munich.

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High Midlife Fitness Levels Linked to Healthier Old Age

WEDNESDAY, Aug. 29 (HealthDay News) -- High midlife fitness levels are significantly associated with a lower risk of developing chronic conditions later in life, according to a study published online Aug. 27 in the Archives of Internal Medicine.

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Dual Effects Noted for Alcohol and Energy Drink Co-Ingestion

WEDNESDAY, Aug. 29 (HealthDay News) -- Although consuming alcohol mixed with energy drinks (AmED) increases alertness and may negate some intoxication-related sedation effects, it can lead to negative physiological and psychological side effects associated with overstimulation, according to a study published online Aug. 15 in Alcoholism: Clinical & Experimental Research.

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Subclinical Atherosclerosis Noted in Diffuse Scleroderma

WEDNESDAY, Aug. 29 (HealthDay News) -- Patients with diffuse systemic sclerosis (SSc), without any clinical evidence of cardiovascular disease, have indicators of subclinical atherosclerosis, according to a study published online Aug. 16 in Arthritis Care & Research.

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Long-Term Thrombosis Rates Similar for Drug-Eluting Stents

WEDNESDAY, Aug. 29 (HealthDay News) -- Two types of drug-eluting stents with distinct antiproliferative properties have similar long-term rates of stent thrombosis and outcomes, including death and heart attack, according to a study published online Aug. 27 in The Lancet to coincide with presentation at the annual European Society of Cardiology Congress, held from Aug. 25 to 29 in Munich.

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Functional Flow Reserve CT Improves Diagnosis of CAD

TUESDAY, Aug. 28 (HealthDay News) -- Noninvasive fractional flow reserve (FFR) computed from computed tomography (CT) (FFRCT) plus CT improves the diagnostic accuracy of coronary artery disease (CAD) compared with CT alone, according to a study published online Aug. 26 in the Journal of the American Medical Association to coincide with presentation at the annual European Society of Cardiology Congress, held from Aug. 25 to 29 in Munich.

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STEMI Mortality Down in France From 1995 to 2010

TUESDAY, Aug. 28 (HealthDay News) -- ST-segment elevation myocardial infarction (STEMI) mortality declined in France from 1995 to 2010 due to greater use of reperfusion therapy and early admission and medications as well as changes in patient characteristics, according to a study published online Aug. 27 in the Journal of the American Medical Association to coincide with presentation at the annual European Society of Cardiology Congress, held from Aug. 25 to 29 in Munich.

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Pharmacist-Led Intervention Benefits Knee Osteoarthritis

TUESDAY, Aug. 28 (HealthDay News) -- Community-based pharmacists can initiate a coordinated care strategy to better identify knee osteoarthritis (OA) and improve function, pain, and quality of life, according to a study published online Aug. 28 in Arthritis Care & Research.

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Sleep Apnea Tied to Insulin Resistance in Young, Lean Men

TUESDAY, Aug. 28 (HealthDay News) -- In healthy, lean, young men, the presence of obstructive sleep apnea (OSA) correlates with insulin resistance and compensatory hyperinsulinemia to maintain normal glucose levels, according to a study published online Aug. 21 in Diabetes Care.

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Gabapentin Efficacious for Refractory Chronic Cough

TUESDAY, Aug. 28 (HealthDay News) -- For patients with refractory chronic cough, treatment with gabapentin is associated with improved cough-specific quality of life and is well-tolerated, according to a study published online Aug. 28 in The Lancet.

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New Diagnostic Definition of Myocardial Infarction Issued

TUESDAY, Aug. 28 (HealthDay News) -- An updated universal definition of myocardial infarction (MI) includes detection of a rise and/or fall in cardiac biomarker values, preferably cardiac troponin (cTn), according to a statement published online Aug. 26 in Circulation to coincide with presentation at the annual European Society of Cardiology Congress, held from Aug. 25 to 29 in Munich.

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LABA Withdrawal Increases Asthma-Related Impairment

TUESDAY, Aug. 28 (HealthDay News) -- For patients with asthma controlled with a combination of an inhaled corticosteroid (ICS) and a long-acting β2-agonist (LABA), withdrawal of the LABA once asthma is controlled correlates with increased asthma-associated impairment, according to a study published online Aug. 27 in the Archives of Internal Medicine.

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Five CSF Markers Differentiate Dementia, Parkinsonism

TUESDAY, Aug. 28 (HealthDay News) -- Levels of five different cerebrospinal fluid (CSF) biomarkers are able to improve differentiation between common dementia and parkinsonian disorders, according to a study published online Aug. 27 in the Archives of Neurology.

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New Class of Drugs Shows Promise for Heart Failure

TUESDAY, Aug. 28 (HealthDay News) -- After 12 weeks of treatment, the first-in-class angiotensin receptor neprilysin inhibitor, LCZ696, lowers N-terminal pro-brain natriuretic peptide (NT-proBNP) levels in patients with New York Heart Association (NYHA) class II to III heart failure and preserves left ventricular ejection fraction (LVEF) significantly more than valsartan, according to a study published online Aug. 26 in The Lancet to coincide with presentation at the annual European Society of Cardiology Congress, held from Aug. 25 to 29 in Munich.

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For Patients With Prior MI, Vorapaxar Cuts Cardiac Events

MONDAY, Aug. 27 (HealthDay News) -- When added to standard antiplatelet treatment, including aspirin, the protease-activated receptor 1 inhibitor vorapaxar reduces the risk of a primary end point of cardiovascular (CV) death, myocardial infarction (MI), or stroke, for patients with a history of MI, according to a study published online Aug. 26 in The Lancet to coincide with presentation at the annual European Society of Cardiology Congress, held from Aug. 25 to 29 in Munich.

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Obesity Up With Transition to Information-Based Society

MONDAY, Aug. 27 (HealthDay News) -- The transition toward an information/knowledge-based society has increased the worldwide prevalence of obesity, according to a report, Waistlines of the World: The Effect of Information and Communications Technology on Obesity, published online Aug. 21 by the Milken Institute.

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Mild Cognitive Decline in Nearly Half Lacunar Stroke Patients

MONDAY, Aug. 27 (HealthDay News) -- Mild cognitive impairment (MCI) is present in nearly half of patients with lacunar stroke, according to a study published online Aug. 18 in the Annals of Neurology.

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Prasugrel, Clopidogrel Similar for Acute Coronary Syndromes

MONDAY, Aug. 27 (HealthDay News) -- For patients with unstable angina or myocardial infarction without ST-segment elevation who do not undergo revascularization, intensified platelet inhibition with prasugrel does not reduce the frequency of the primary end point (death from cardiovascular causes, myocardial infarction, or stroke) and has similar risks of bleeding as clopidogrel, according to a study published online Aug. 26 in the New England Journal of Medicine to coincide with presentation at the annual European Society of Cardiology Congress, held from Aug. 25 to 29 in Munich.

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In Type 2 DM, Proteinuria With SBP <130 Ups CVD Mortality

FRIDAY, Aug. 24 (HealthDay News) -- Patients with type 2 diabetes, proteinuria, and systolic blood pressure (BP) <130 mm Hg are at an increased risk of total and cardiovascular disease (CVD) mortality, suggesting that proteinuria should be taken into account when establishing target systolic BP levels for prevention of fatal CVD events, according to research published online Aug. 14 in the Journal of Internal Medicine.

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Stress Causes Lower INR in VTE Patients Not on Blood Thinners

FRIDAY, Aug. 24 (HealthDay News) -- The effect of psychological distress on clotting times and clotting factors varies in patients with venous thromboembolism (VTE) and depends on whether or not they are receiving oral anticoagulant (OAC) therapy, according to a Swiss study published in the August issue of the Journal of Thrombosis and Haemostasis.

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Claustrophobia Linked to Depression With Back Pain

FRIDAY, Aug. 24 (HealthDay News) -- Claustrophobia is tied to higher rates of depression and psychological distress, but not disability, in back pain patients, according to a study published in the August issue of the Journal of Spinal Disorders & Techniques.

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Multidisciplinary Approach Cuts Symptoms of Fibromyalgia

FRIDAY, Aug. 24 (HealthDay News) -- Multidisciplinary treatment adapted for women with low educational levels is superior to conventional pharmacotherapy in reducing key symptoms of fibromyalgia (FM), including sleep disturbances, catastrophizing, and psychological distress, according to research published online Aug. 16 in Arthritis Care & Research.

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Anorexics Overestimate Own Body Size, but Not That of Others

FRIDAY, Aug. 24 (HealthDay News) -- Patients with anorexia nervosa (AN) tend to overestimate the size of their body but not the bodies of others, basing their weight and body dimensions on their pre-AN body dimensions, according to research published online Aug. 22 in PLoS One.

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New Model Explains How Lungs Clear Foreign Matter

FRIDAY, Aug. 24 (HealthDay News) -- Mucus in the lungs clears foreign matter by moving along a brush-like periciliary layer rather than a watery layer, which keeps it from sticking to the airway surface, according to a study published in the Aug. 24 issue of Science.

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Procedure Aids Severe, Rigid Scoliosis in Low-Weight Adults

FRIDAY, Aug. 24 (HealthDay News) -- For patients with severe and rigid scoliosis and low body weight, a two-stage vertebral column resection (VCR) procedure with posterior pedicle screw instrumentation can achieve good correction of scoliosis, according to a study published online Aug. 20 in The Spine Journal.

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In Diabetes, Gastric Emptying Remains Stable Over Time

FRIDAY, Aug. 24 (HealthDay News) -- Gastric emptying of solids and liquids and gastrointestinal symptoms remain stable over time in patients with long-term type 1 and type 2 diabetes, according to a study published online Aug. 13 in Diabetes Care.

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Muscle-Related Statin Effects Seem to Correlate With Potency

FRIDAY, Aug. 24 (HealthDay News) -- The rates of muscle-related adverse effects (AEs) differ greatly for various statins, with the highest reported rates seen for rosuvastatin, according to research published online Aug. 22 in PLoS One.

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Outcomes Similar With Partial, Whole Breast Irradiation

FRIDAY, Aug. 24 (HealthDay News) -- Accelerated partial breast irradiation (APBI) yields five-year clinical outcomes and patterns of failure similar to those achieved with whole breast irradiation (WBI), with excellent three-year survival for women who develop an ipsilateral breast tumor recurrence (IBTR), according to a study published in the Sept. 1 issue of Cancer.

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Melanoma Risk Declines With Self-Exams Plus Doctor Visit

FRIDAY, Aug. 24 (HealthDay News) -- Risk of deeper melanomas is reduced with self-examination of the skin one to 11 times a year, according to a study published online Aug. 16 in the British Journal of Dermatology.

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Sequencing Identifies Spread of Deadly Bacterial Outbreak

THURSDAY, Aug. 23 (HealthDay News) -- A drug-resistant bacterial strain that caused a serious outbreak resulting in deaths has been traced back to the original patient, and transmission patterns have been identified based on sequencing the genomes of the bacterial isolates, according to research published in the Aug. 22 issue of Science Translational Medicine.

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Study Casts Doubts on Brain Regions for Self-Awareness

THURSDAY, Aug. 23 (HealthDay News) -- The case of a self-aware man with extensive damage to brain regions thought to be critical for self-awareness suggests that a more diffuse brain network and other brain networks are involved, according to a study published online Aug. 22 in PLoS One.

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Neti Pots Linked to Deaths From Amebic Infection

THURSDAY, Aug. 23 (HealthDay News) -- Two patients who died of an amebic infection had no history of freshwater exposure but had ameba in their household plumbing and used a nasal irrigation device for sinus problems, according to a study published online Aug. 22 in Clinical Infectious Diseases.

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Mortality Rates Down for Adult Trauma Patients in Last Decade

THURSDAY, Aug. 23 (HealthDay News) -- The mortality rate for adult patients admitted to trauma centers in Pennsylvania has declined over the past decade, according to research published in the August issue of the Archives of Surgery.

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Dual Action Antibody Reverses Menopausal Bone Loss

THURSDAY, Aug. 23 (HealthDay News) -- An antibody can reverse bone loss in menopausal mice by both blocking bone breakdown and stimulating bone formation, according to an experimental study published online Aug. 20 in the Proceedings of the National Academy of Sciences.

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Modifiable Risk Factors Key in Social Inequality of Diabetes

THURSDAY, Aug. 23 (HealthDay News) -- Modifiable risk factors, particularly health behaviors and body mass index (BMI), measured repeatedly over time, account for about half of the socioeconomic differential observed in type 2 diabetes, according to a study published online Aug. 21 in BMJ.

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New Decision Aid for Treatment of Herniated Disc Beneficial

THURSDAY, Aug. 23 (HealthDay News) -- A new patient decision instrument meets the criteria of acceptability, reliability, and validity, and improves the quality of patient decision-making for treatment of a herniated disc, according to a study published in the Aug. 15 issue of Spine.

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Nearly Half of U.S. Physicians Have Symptoms of Burnout

THURSDAY, Aug. 23 (HealthDay News) -- Nearly half of all U.S. physicians report at least one symptom of burnout, with family, internal, and emergency medicine specialists reporting the highest rates of burnout, according to research published online Aug. 20 in the Archives of Internal Medicine.

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Psychological Consequences Up for Spouses of MI Victims

WEDNESDAY, Aug. 22 (HealthDay News) -- Spouses of individuals who have a sudden heart attack are more likely to experience depression, anxiety, and suicide, even if the individual survives, than spouses of those who experience other illnesses, according to a study published online Aug. 21 in the European Heart Journal.

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Tattoo Ink Found to Be Source of M. Chelonae Outbreak

WEDNESDAY, Aug. 22 (HealthDay News) -- Premixed tattoo ink has been found to be the source of an outbreak of Mycobacterium chelonae in 19 patients in Rochester, N.Y., according to a study published online Aug. 22 in the New England Journal of Medicine.

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De Novo Mutation Rate Higher in Children of Older Fathers

WEDNESDAY, Aug. 22 (HealthDay News) -- Children of older fathers have a higher rate of new mutations, which may affect the risk of diseases such as autism and schizophrenia, according to a study published in the Aug. 23 issue of Nature.

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Opportunistic Infections Associated With Antibodies to IFN

WEDNESDAY, Aug. 22 (HealthDay News) -- Neutralizing anti-interferon-γ autoantibodies are detected in most Asian adults with multiple opportunistic infections, according to a study published in the Aug. 23 issue of the New England Journal of Medicine.

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Bariatric Surgery Cuts Incidence of Type 2 Diabetes in Obese

WEDNESDAY, Aug. 22 (HealthDay News) -- Bariatric surgery is very effective in reducing the long-term incidence of type 2 diabetes in obese individuals, according to a study published in the Aug. 23 issue of the New England Journal of Medicine.

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Low Back Pain Outcomes Not Improved by Early Imaging

WEDNESDAY, Aug. 22 (HealthDay News) -- For workers with low back pain, early magnetic resonance imaging (MRI) is not associated with better health outcomes at one year, according to a study published in the Aug. 15 issue of Spine.

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Lower MI Risk With TNF Inhibitor Therapy for Psoriasis

WEDNESDAY, Aug. 22 (HealthDay News) -- Patients with psoriasis who are treated with tumor necrosis factor (TNF) inhibitors have a significantly lower risk and incidence of myocardial infarction (MI) compared with those who are treated with topical agents, according to a study published online Aug. 20 in the Archives of Dermatology.

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Mindfulness Stress Reduction Reduces Loneliness in Elderly

WEDNESDAY, Aug. 22 (HealthDay News) -- An eight-week mindfulness-based stress reduction (MBSR) program reduces loneliness compared with a wait-list control, and also reduces pro-inflammatory gene expression in older adults, according to a study published online July 20 in Brain, Behavior, and Immunity.

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Low HDL Cholesterol Ups Risk of Diabetic Nephropathy

WEDNESDAY, Aug. 22 (HealthDay News) -- High-density lipoprotein cholesterol (HDL-C) is an independent risk factor for the development of diabetic nephropathy, but not retinopathy, in patients with type 2 diabetes, according to research published online Aug. 13 in Diabetes Care.

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At-Home Diode Laser Effective for Permanent Hair Reduction

WEDNESDAY, Aug. 22 (HealthDay News) -- Eight treatments with a home-use diode laser provide effective and safe permanent hair reduction one year after the last treatment, according to research published in the September issue of Lasers in Surgery and Medicine.

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T Cells Key in Atherosclerosis-Linked Inflammation

WEDNESDAY, Aug. 22 (HealthDay News) -- In a mouse model of atherosclerosis, CD4+ T cells interact with antigen-presenting cells (APCs) in the presence of cognate antigen, leading to cell activation and proliferation and the secretion of proinflammatory cytokines, according to an experimental study published online Aug. 13 in the Journal of Clinical Investigation.

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Meta-Analysis Links Statins to Reduced Pancreatitis Risk

TUESDAY, Aug. 21 (HealthDay News) -- For patients with normal or mildly elevated triglyceride levels, statin therapy correlates with a reduction in the risk of pancreatitis, according to a meta-analysis published in the Aug. 22/29 issue of the Journal of the American Medical Association.

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Drug-Eluting Stents Lead to Fewer Adverse Cardiac Events

TUESDAY, Aug. 21 (HealthDay News) -- Among ST-segment elevation myocardial infarction (STEMI) patients, the use of biolimus-eluting stents with biodegradable polymer results in a lower rate of major adverse cardiac events, compared with patients with bare-metal stents, at one year following primary percutaneous coronary intervention (PCI), according to a study published in the Aug. 22/29 issue of the Journal of the American Medical Association.

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Novel Risk Markers Improve Prediction of Heart Disease

TUESDAY, Aug. 21 (HealthDay News) -- The addition of certain novel risk markers can improve risk prediction for incident coronary heart disease (CHD) or cardiovascular disease (CVD) above that of the Framingham Risk Score (FRS) in intermediate-risk individuals; while the addition of the carotid intima-media thickness (CIMT) offers limited improvement in risk prediction for first-time myocardial infarction or stroke, above that of the FRS, according to two studies published in the Aug. 22/29 issue of the Journal of the American Medical Association.

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Evidence-Based Public Health Interventions Identified

TUESDAY, Aug. 21 (HealthDay News) -- Evidence-based public health interventions to improve dietary habits, increase physical activity, and reduce tobacco use are identified in an American Heart Association scientific statement published online Aug. 20 in Circulation.

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BMI, Post-Exercise Knee Laxity Change Tied to OA Progression

TUESDAY, Aug. 21 (HealthDay News) -- In patients with osteoarthritis (OA) of the knee, changes in knee joint laxity during stair climbing or other repetitive physical activity and baseline body mass index (BMI) are associated with disease progression, according to a study published online Aug. 8 in Arthritis & Rheumatism.

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Prior Substance Abuse Linked to Opioid Abuse in Young Men

TUESDAY, Aug. 21 (HealthDay News) -- Any prior substance abuse is associated with current abuse of prescription opioids among 18- to 25-year-old men, but only previous marijuana use correlates with subsequent prescription opioid abuse in young women, according to a study published online Aug. 21 in the Journal of Adolescent Health.

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Study Identifies Sleep Apnea in 50 Percent of Women

TUESDAY, Aug. 21 (HealthDay News) -- Half of adult women aged 20 to 70 years may have obstructive sleep apnea, which correlates with age, obesity, and hypertension, according to a study published online Aug. 16 in the European Respiratory Journal.

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Factors Tied to Photoprotection ID'd for Organ Recipients

TUESDAY, Aug. 21 (HealthDay News) -- For organ transplant recipients, patients factors, including sex and skin type, and receipt of advice from health care providers, are both associated with sun protective behaviors, according to a study published online Aug. 9 in the British Journal of Dermatology.

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Family Hx of Early Death Ups Risk of Early Cardiac Disease

TUESDAY, Aug. 21 (HealthDay News) -- The risk of early cardiovascular disease in patients younger than 50 years of age is significantly and consistently increased for those with a family history of premature cardiovascular death, according to a study published in the Aug. 28 issue of the Journal of the American College of Cardiology.

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Resting Heart Rate Predicts Overall, Cardiovascular Mortality

TUESDAY, Aug. 21 (HealthDay News) -- High resting heart rates seem to be predictive of increased risk for overall and cardiovascular disease (CVD) mortality and shorter survival times, according to a study published in the Aug. 15 issue of The American Journal of Cardiology.

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Brain Damage Linked to Believing Misleading Ads

MONDAY, Aug. 20 (HealthDay News) -- Damage to a particular region of the brain makes individuals more likely to believe a misleading advertisement, which could explain why some elderly fall for fraud schemes, according to a study published online July 9 in Frontiers in Decision Neuroscience.

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Increased Stroke Risk at 30-Days Post-CABG Versus PCI

MONDAY, Aug. 20 (HealthDay News) -- The risk of stroke at 30 days is significantly higher in patients who undergo coronary revascularization with coronary artery bypass graft (CABG) surgery compared to those who undergo percutaneous coronary intervention (PCI), according to research published in the Aug. 28 issue of the Journal of the American College of Cardiology.

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Post-Polyp Detection, CRC Risk ID'd by Colonoscopy Factors

MONDAY, Aug. 20 (HealthDay News) -- In the community setting, after colonoscopic polyp detection, colonoscopy-related factors such as incomplete polyp removal and lack of surveillance colonoscopies are more important than polyp characteristics in predicting subsequent colorectal cancer (CRC) risk, according to a study published in the Aug. 21 issue of the Annals of Internal Medicine.

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2012 Indicators of Well-Being for Older Americans Issued

MONDAY, Aug. 20 (HealthDay News) -- The estimates of selected indicators for well-being for older Americans for 2012 have been released by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics.

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Obesity Plus Metabolic Factors Speeds Up Cognitive Decline

MONDAY, Aug. 20 (HealthDay News) -- For individuals who are metabolically abnormal, increasing body mass index (BMI) correlates with faster cognitive decline, according to a study published in the Aug. 21 issue of Neurology.

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Yo-Yo Dieters Still Benefit From Weight Loss Efforts

MONDAY, Aug. 20 (HealthDay News) -- Yo-yo dieting does not negatively affect participation in lifestyle intervention or the benefits of diet and exercise, according to a study published online Aug. 14 in Metabolism -- Clinical and Experimental.

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Prevalence of TB, Hepatitis C, HIV High Among Homeless

MONDAY, Aug. 20 (HealthDay News) -- The global prevalence of tuberculosis, hepatitis C virus infection, and HIV is high among homeless people, although significant heterogeneity is seen in prevalence estimates, according to a study published online Aug. 20 in The Lancet Infectious Diseases.

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Azithromycin Treats Non-Cystic Fibrosis Bronchiectasis

MONDAY, Aug. 20 (HealthDay News) -- For patients with non-cystic fibrosis bronchiectasis with at least one exacerbation in the past year, treatment with the macrolide antibiotic azithromycin correlates with a reduced rate of event-based exacerbations, according to a study published in the Aug. 18 issue of The Lancet, a theme issue on respiratory medicine.

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Karate Black Belts Have Differences in Brain Structure

MONDAY, Aug. 20 (HealthDay News) -- Black belts in karate have differences in white matter brain structure that are associated with their voluntary control of movement, according to a study published online Aug. 14 in Cerebral Cortex.

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Study Shows 'SuperAgers' Have Thicker Cortex, No Atrophy

MONDAY, Aug. 20 (HealthDay News) -- 'SuperAgers,' individuals over the age of 80 with episodic memory performance as good as normative values for 50- to 65-year-olds, do exist, and they have a thicker cerebral cortex, with no atrophy, according to a study published online Aug. 16 in the Journal of the International Neuropsychological Society.

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Men at Greater Lifetime Risk of End-Stage Renal Disease

MONDAY, Aug. 20 (HealthDay News) -- The lifetime risk of developing end-stage renal disease (ESRD) is higher for men than women, at all ages and estimated glomerular filtration rate (eGFR) strata, according to a study published online Aug. 16 in the Journal of the American Society of Nephrology.

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Study Links Eating Egg Yolks With Carotid Plaque Area

FRIDAY, Aug. 17 (HealthDay News) -- Eating three or more egg yolks, which are high in cholesterol, per week may increase the rate of carotid plaque area build-up, according to a study published online Aug. 10 in Atherosclerosis.

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Urinary BPA Increased in Severe Coronary Artery Disease

FRIDAY, Aug. 17 (HealthDay News) -- Bisphenol A (BPA) exposure, as measured by urinary BPA (uBPA) concentrations, is higher in individuals with severe coronary artery disease (CAD) compared to those with no vessel disease, according to a study published online Aug. 15 in PLoS One.

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Ecallantide Efficacious for Hereditary Angioedema Attacks

FRIDAY, Aug. 17 (HealthDay News) -- Patients with unpredictable and recurring attacks of acute hereditary angioedema (HAE) may be effectively treated with ecallantide, with relapse occurring in a small proportion of patients and little evidence of rebound, according to a study published in the September issue of Allergy.

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Mepolizumab Effective in Treating Eosinophilic Asthma

FRIDAY, Aug. 17 (HealthDay News) -- For patients with severe eosinophilic asthma, treatment with mepolizumab, a monoclonal antibody against interleukin 5, is effective at reducing clinically significant exacerbations, according to a study published in the Aug. 18 issue of The Lancet, a theme issue on respiratory medicine.

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Good Transplant Outcomes in Hypertrophic Cardiomyopathy

FRIDAY, Aug. 17 (HealthDay News) -- Post-heart transplant survival does not differ significantly between patients with hypertrophic cardiomyopathy (HC) and those with other types of heart disease, according to a study published in the Aug. 15 issue of The American Journal of Cardiology.

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Study Finds Tobacco Use High in Developing Countries

FRIDAY, Aug. 17 (HealthDay News) -- Despite global tobacco control efforts, in low- and middle-income countries, nearly half of men use tobacco, women are starting to smoke at earlier ages, and quit ratios are low, according to a study published in the Aug. 18 issue of The Lancet, a theme issue on respiratory medicine.

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Delayed Gratification at Age 4 Predictive of BMI in Adulthood

FRIDAY, Aug. 17 (HealthDay News) -- Delayed gratification among preschoolers can predict body mass index (BMI) about 30 years later, according to a study published online Aug. 16 in The Journal of Pediatrics.

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Even Minor Changes in Physical Activity Improve Bone Health

FRIDAY, Aug. 17 (HealthDay News) -- For premenopausal women, physical activity correlates with decreased sclerostin, increased serum insulin-like growth factor-I (s-IGF-I), and increased bone formation markers, according to a study published online Aug. 3 in the Journal of Clinical Endocrinology & Metabolism.

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Vancomycin Overprescribed in Bloodstream MSSA Infections

FRIDAY, Aug. 17 (HealthDay News) -- In U.S. dialysis centers treating end-stage renal (ESRD) patients with methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia, vancomycin is overprescribed, despite evidence of lower rates of hospitalization and death in cefazolin-treated patients, according to a study published online Aug. 16 in the Journal of the American Society of Nephrology.

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Autoantibodies Predict Severity of IgA Ne

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