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Category: Endocrinology | Monthly Briefing

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September 2012 Briefing - Diabetes & Endocrinology

Last Updated: October 01, 2012.

 

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Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for September 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Standards for Diabetes Education, Support Updated

FRIDAY, Sept. 28 (HealthDay News) -- A task force from the American Association of Diabetes Educators and the American Diabetes Association has updated the national standards for diabetes self-management education and support, according to a report published online Sept. 20 in Diabetes Care.

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History of Sexual Abuse Slows Response to Bariatric Surgery

FRIDAY, Sept. 28 (HealthDay News) -- Although studies suggest that individuals with a history of sexual abuse may experience less weight loss soon after bariatric surgery, most individuals still benefit from the surgical procedure, with increased weight loss seen over time, according to research published in the October issue of Obesity Reviews.

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Review Finds Little Impact of Exercise Interventions on Kids

FRIDAY, Sept. 28 (HealthDay News) -- Interventions to increase physical activity in children and adolescents have little impact, according to research published online Sept. 27 in BMJ.

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Insulin Sensitivity Lower in Adults Born Preterm

THURSDAY, Sept. 27 (HealthDay News) -- Middle-aged adults who were born preterm, even moderately preterm (32 to 36 weeks' gestation), are less insulin sensitive compared with adults who were born at term, according to research published in the October issue of Diabetes.

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Arterial Stiffness Inversely Tied to Plasma Adiponectin Levels

THURSDAY, Sept. 27 (HealthDay News) -- Arterial stiffness is inversely related to plasma adiponectin levels in young, normotensive patients with type 1 diabetes, according to a study published online Sept. 21 in Diabetes Care.

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Gut Bacteria Offers Clues About Risk of Developing T2DM

WEDNESDAY, Sept. 26 (HealthDay News) -- Gut bacteria from individuals with and without diabetes differ substantially and can be used to accurately discriminate between those with and without the disease, according to a study published online Sept. 26 in Nature.

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Trio of Studies Look at Impact of Sugary Drinks on Weight

FRIDAY, Sept. 21 (HealthDay News) -- For adults, children, and teens, drinking sugar-sweetened beverages correlates with increases in body mass index (BMI) and obesity, according to three studies published online Sept. 21 in the New England Journal of Medicine to coincide with presentation at the annual meeting of The Obesity Society, held from Sept. 20 to 24 in San Antonio, Texas.

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Effect of BMI Category on CVD Risk Quantified in Children

WEDNESDAY, Sept. 26 (HealthDay News) -- For school-aged children, cardiovascular disease risk parameters are worse for those who are overweight, and substantially worse for those who are obese, compared with their normal-weight peers, according to a review published online Sept. 25 in BMJ.

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Efficacy of Black Cohosh for Menopausal Symptoms Unclear

WEDNESDAY, Sept. 26 (HealthDay News) -- There is insufficient evidence to support the use of black cohosh for menopausal symptoms, according to the results of a systematic literature review published online Sept. 12 in The Cochrane Library.

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Drugs Similar in Efficacy for Neuropathic Pain in Diabetes

WEDNESDAY, Sept. 26 (HealthDay News) -- In the treatment of patients with chronic diabetic peripheral neuropathic pain (DPNP), there are no significant differences in pain-relief efficacy between amitriptyline, duloxetine, and pregabalin; however, pregabalin improves sleep continuity and duloxetine improves daytime functioning, according to research published online Sept. 18 in Diabetes Care.

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BPA Alters Oogenesis and Follicle Formation in Primates

TUESDAY, Sept. 25 (HealthDay News) -- Rhesus monkeys exposed to bisphenol A (BPA) experience alterations in early oogenesis and follicle formation, according to a study published online Sept. 24 in the Proceedings of the National Academy of Sciences.

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Stress-Weight Link in Black and White Teen Girls Studied

TUESDAY, Sept. 25 (HealthDay News) -- Increased stress is tied to weight gain in teenage girls, particularly black girls, according to a study published online Sept. 20 in the Annals of Behavioral Medicine.

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Taste Perceptions Differ for Obese, Non-Obese Children

MONDAY, Sept. 24 (HealthDay News) -- Obese children are less able than their normal-weight peers to identify taste qualities, according to a study published online Sept. 20 in the Archives of Disease in Childhood.

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Increased Prevalence of Obesity in Rural Areas

FRIDAY, Sept. 21 (HealthDay News) -- Rates of obesity are significantly higher among rural adults compared with urban residents, according to a study published in The Journal of Rural Health.

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Urge to Overeat Linked to Production of Natural Narcotic

FRIDAY, Sept. 21 (HealthDay News) -- When presented with tasty foods, the brain produces the opioid peptide enkephalin that stimulates an unexpected reward center in the brain and leads to overeating, according to a study published online Sept. 20 in Current Biology.

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Stress-Reducing Effect of Acute Exercise Persists

THURSDAY, Sept. 20 (HealthDay News) -- The anxiety-lowering effect of exercise seems to persist even after exposure to emotional stimuli, according to a study published online Aug. 14 in Medicine & Science in Sports & Exercise.

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African-Americans Less Adherent to DASH Diet for Lowering BP

THURSDAY, Sept. 20 (HealthDay News) -- Greater adherence to the Dietary Approaches to Stop Hypertension (DASH) diet is associated with larger reductions in blood pressure (BP), independent of weight loss; however, African-Americans are less likely to adhere to the DASH diet, according to a study published online Sept. 19 in the Journal of the Academy of Nutrition and Dietetics.

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AHA: Sesame, Rice Oil Blend Lowers Blood Pressure

THURSDAY, Sept. 20 (HealthDay News) -- Daily use of a blend of sesame and rice bran oils can significantly lower blood pressure and lipids in patients with hypertension, according to a study presented at the American Heart Association's High Blood Pressure Research Scientific Sessions, held from Sept. 19 to 22 in Washington, D.C.

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Higher Dietary Fructose Tied to Lower Liver Energy Stores

WEDNESDAY, Sept. 19 (HealthDay News) -- Increased dietary fructose consumption may impair hepatocellular energy homeostasis, as seen with reduced levels of liver adenosine triphosphate (ATP), with lower levels seen in those with high uric acid (UA) levels, according to a study published in the September issue of Hepatology.

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A 5 Percent Reduction in BMI Could Alter U.S. Obesity Course

WEDNESDAY, Sept. 19 (HealthDay News) -- Obesity trends for 2030 could see considerable improvement if there was a 5 percent reduction in average body mass index for all adults by state, according to a report published online Sept. 18 by the Trust for America's Health (TFAH) and the Robert Wood Johnson Foundation (RWJF).

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Long-Term Benefits of Gastric Bypass Surgery Evaluated

TUESDAY, Sept. 18 (HealthDay News) -- Among obese patients, gastric bypass surgery correlates with higher rates of diabetes remission and lower risk of cardiovascular disease, has little effect on the severity of sleep apnea, and only reduces health care use after the sixth year post-surgery, according to three studies published in the Sept. 19 issue of the Journal of the American Medical Association, a theme issue on obesity.

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Bisphenol A Linked to Obesity in Children and Teens

TUESDAY, Sept. 18 (HealthDay News) -- Children and adolescents in the United States with elevated levels of urinary bisphenol A (BPA), a ubiquitous breakdown product of coatings used in food and beverage containers, are about twice as likely to be obese, according to a study published in the Sept. 19 issue of the Journal of the American Medical Association, a theme issue on obesity.

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Adipose Tissue Distribution Aids Diabetes Risk Determination

TUESDAY, Sept. 18 (HealthDay News) -- Obese adults with dysfunctional adiposity (excess visceral body fat distribution and insulin resistance) are more likely to develop type 2 diabetes than obese adults with general adiposity, according to a study published in the Sept. 19 issue of the Journal of the American Medical Association, a theme issue on obesity.

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Hip Circumference Inversely Tied to Diabetes Risk

TUESDAY, Sept. 18 (HealthDay News) -- There is an inverse relationship between hip circumference and risk of type 2 diabetes mellitus (T2DM), according to a meta-analysis published online Sept. 3 in Obesity Reviews.

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Ethnic Variation Seen in Level of Pancreatic Triglycerides

MONDAY, Sept. 17 (HealthDay News) -- There is considerable ethnic variation in the levels of pancreatic triglycerides (TGs) and in β-cell dysfunction, according to research published online Sept. 11 in Diabetes Care.

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Mechanism of Smoking-Induced Insulin Resistance Elucidated

MONDAY, Sept. 17 (HealthDay News) -- Smoking-induced insulin resistance, which improves with smoking cessation, may be due to activation of mammalian target of rapamycin (mTOR), according to a study published online Sept. 10 in Diabetes.

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White Matter Structural Changes ID'd in Children With T1DM

MONDAY, Sept. 17 (HealthDay News) -- Children with type 1 diabetes have significant structural differences in the white matter of their brain compared to healthy children, which correlates with hemoglobin A1c (HbA1c) values, according to a study published online Sept. 10 in Diabetes Care.

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Spindle Abnormalities Seen in Oocytes of Severely Obese

FRIDAY, Sept. 14 (HealthDay News) -- Oocytes from severely obese women undergoing in vitro fertilization display significant spindle abnormalities, which may contribute to poor reproductive outcomes, according to a study published online Sept. 11 in Human Reproduction.

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Thyroid-Stimulating Hormone Up Over Time in Oldest Old

FRIDAY, Sept. 14 (HealthDay News) -- For the oldest old, increases in thyroid-stimulating hormone (TSH) occur over time but do not correlate with mortality, according to a study published online Aug. 9 in the Journal of Clinical Endocrinology & Metabolism.

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Exposure to Air Pollution Tied to Low Vitamin D in Newborns

FRIDAY, Sept. 14 (HealthDay News) -- Exposure to two urban pollutants during pregnancy correlates with a decrease in the blood serum levels of 25-hydroxyvitamin D (25[OH]D) of newborns, according to a study published online Aug. 17 in the Journal of Clinical Endocrinology & Metabolism.

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For Youth, Only Vigorous Activity Reduces Cardiometabolic Risk

FRIDAY, Sept. 14 (HealthDay News) -- In youth, vigorous physical activity (PA), but not light or moderate PA, correlates with improved measures of cardiometabolic risk, according to research published online Sept. 10 in the Archives of Pediatrics & Adolescent Medicine.

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Review: Inflammation's Role in Obesity-Colorectal Cancer Link

THURSDAY, Sept. 13 (HealthDay News) -- A new review summarizes the ways in which inflammation and altered metabolism are associated with colorectal cancer in obese individuals; the review was published online Sept. 3 in Obesity Reviews.

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Diabetes Outcome Better for Patients With Empathetic Docs

THURSDAY, Sept. 13 (HealthDay News) -- Physician empathy, as measured by a validated scale, correlates with clinical outcome for patients with diabetes, with better outcome for those with doctors with high empathy, according to a study published in the September issue of Academic Medicine.

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Rare Cancer Syndrome Linked to Lower Diabetes Risk

WEDNESDAY, Sept. 12 (HealthDay News) -- People with Cowden syndrome, with tumor-suppressor phosphatase and tensin homologue (PTEN) mutations that increase their risk of cancer, have enhanced sensitivity to insulin even though they are more likely to be obese, according to a study published in the Sept. 13 issue of the New England Journal of Medicine.

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Vitamin A Metabolite Linked to Sex-Specific Fat Accumulation

WEDNESDAY, Sept. 12 (HealthDay News) -- An enzyme that regulates the levels of a vitamin A metabolite may play a role in explaining why women are more prone to obesity and accumulation of abdominal fat, particularly after menopause, according to a study published online Aug. 28 in Diabetes.

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Review: Omega-3s Do Not Reduce Risk of Cardio Events

TUESDAY, Sept. 11 (HealthDay News) -- Supplementation with omega-3 polyunsaturated fatty acids (PUFAs) is not associated with a statistically significant reduction in major cardiovascular end points, according to research published in the Sept. 12 issue of the Journal of the American Medical Association.

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Obese Teens Self-Report Eating Less Than Healthy-Weight Peers

MONDAY, Sept. 10 (HealthDay News) -- Younger obese children report consuming more daily calories than their healthy-weight peers, while obese adolescents report consuming fewer daily calories, suggesting that excessive energy intake in early childhood may lead to onset of obesity, according to a study published online Sept. 10 in Pediatrics.

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No Gender Effect on PCI Outcome in Acute Coronary Syndrome

FRIDAY, Sept. 7 (HealthDay News) -- There are no significant gender differences in outcomes between men and women undergoing percutaneous coronary intervention (PCI) with drug-eluting stent (DES) for the treatment of acute coronary syndrome (ACS), according to a study published in the Sept. 1 issue of The American Journal of Cardiology.

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Not All Docs/Nurses Want to Be Asked About Hand Hygiene

FRIDAY, Sept. 7 (HealthDay News) -- Although most health care workers (HCWs) appreciate the role of patients in preventing health care-associated infection, a considerable proportion are uncomfortable with patients asking about their hand hygiene, according to a letter published online Sept. 3 in the Archives of Internal Medicine.

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Fructose Consumption Impairs Insulin Sensitivity

FRIDAY, Sept. 7 (HealthDay News) -- High levels of fructose can affect hepatic insulin sensitivity, while even moderate consumption of fructose and sucrose can significantly alter lipid profiles in healthy young men, according to research published online Aug. 28 in Diabetes Care.

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Good Prognosis for Metabolically Healthy Obese

THURSDAY, Sept. 6 (HealthDay News) -- Individuals who are metabolically healthy but obese have a better prognosis than metabolically abnormal, obese adults; and for adults with acute coronary syndrome (ACS), mortality follows a U-shaped pattern with increasing body mass index (BMI), according to two studies published online Sept. 4 in the European Heart Journal.

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Genetic Counseling Doesn't Affect Pre-Diabetes Behavior

THURSDAY, Sept. 6 (HealthDay News) -- Receiving genetic risk counseling does not significantly alter self-reported motivation or prevention program adherence for overweight individuals at risk for type 2 diabetes, according to a study published online Aug. 28 in Diabetes Care.

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Dynamic Diffuse Optical Tomography Can Diagnose PAD

THURSDAY, Sept. 6 (HealthDay News) -- Dynamic diffuse optical tomography (DDOT), a noninvasive, non-ionizing imaging modality, may be a useful new tool for diagnosing peripheral arterial disease (PAD), even in patients with diabetes, according to a study published in the Sept. 1 issue of Biomedical Optics Express.

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Maternal Smoking Link to Teen Obesity Mediated by Fat Intake

THURSDAY, Sept. 6 (HealthDay News) -- The increased risk of obesity seen in adolescents who experienced prenatal exposure to maternal cigarette smoking (PEMCS) is associated with enhanced dietary intake of fat, which may be partially mediated by changes in the amygdala, according to research published online Sept. 3 in the Archives of General Psychiatry.

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Congenital Disease Linked to Adipocyte Development

THURSDAY, Sept. 6 (HealthDay News) -- Some patients with congenital generalized lipodystrophy (CGL), who lack adipocytes and develop severe insulin resistance, have a defect in adipocyte development that can be partially reversed, according to a study published online Aug. 28 in Diabetes.

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Clopidogrel After MI Less Effective in Diabetes Patients

WEDNESDAY, Sept. 5 (HealthDay News) -- Clopidogrel therapy following a heart attack does less to reduce the risk of death in patients with diabetes than in those without diabetes, according to a study published in the Sept. 5 issue of the Journal of the American Medical Association.

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Vitamin D Repletion Offers No Short-Term Benefit in Lipids

TUESDAY, Sept. 4 (HealthDay News) -- For vitamin D deficient adults, repletion of vitamin D is not associated with short-term improvement in the lipid profile, according to a study published online Sept. 4 in Arteriosclerosis, Thrombosis, and Vascular Biology.

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Plasma Glucose Tied to Atrophy in Hippocampus, Amygdala

TUESDAY, Sept. 4 (HealthDay News) -- For cognitively healthy individuals without type 2 diabetes, high plasma levels within the normal range are associated with atrophy in the hippocampus and amygdala, according to a study published in the Sept. 4 issue of Neurology.

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Metabolic Syndrome Affects Teens' Cognitive Performance

TUESDAY, Sept. 4 (HealthDay News) -- There is evidence for lower cognitive performance and changes in the brain's structural integrity among adolescents with metabolic syndrome (MetS), according to a study published online Sept. 3 in Pediatrics.

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