Here are what the editors at HealthDay consider to be the most important developments in Urology for September 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
SNPs Linked to Erectile Dysfunction After Radiotherapy
FRIDAY, Sept. 28 (HealthDay News) -- Twelve single nucleotide polymorphisms (SNPs) are associated with development of erectile dysfunction (ED) following radiotherapy for prostate cancer, according to a study published online Sept. 28 in the International Journal of Radiation Oncology*Biology*Physics.
Protein Linked to Male Infertility Can Activate Eggs
TUESDAY, Sept. 25 (HealthDay News) -- Injecting eggs with a recombinant human phospholipase Cζ (PLCζ), a protein linked to male infertility, can activate calcium ion oscillations, which are necessary for oocyte activation and successful embryo development, according to a study published online Sept. 24 in Fertility and Sterility.
Surveillance for Low-Risk Prostate Cancer Examined
MONDAY, Sept. 24 (HealthDay News) -- For men with low-risk prostate cancer, projections show that active surveillance may result in a modest decline in prostate cancer-specific survival, but allows men to remain treatment-free for several more years compared with immediate radical prostatectomy, according to a study published online Sept. 24 in Clinical Cancer Research.
Decrease Seen in Global Peri-Op, Anesthesia-Related Mortality
FRIDAY, Sept. 21 (HealthDay News) -- Over the last five decades, there has been a decrease in perioperative and anesthesia-related mortality, according to a study published in the Sept. 22 issue of The Lancet, a theme issue on surgery.
Leaving Balloon in Is Safe in Urinary Sphincter Revision
FRIDAY, Sept. 21 (HealthDay News) -- Intentionally leaving the pressure-regulating balloon in place during a non-infected artificial urinary sphincter (AUS) revision procedure is safe and is not associated with infection or complications, according to research published online Sept. 13 in The Journal of Sexual Medicine.
Bladder Cancer Survival Similar for Partial, Radical Cystectomy
THURSDAY, Sept. 20 (HealthDay News) -- For select patients with bladder cancer, there is no difference in metastasis-free or cancer-specific survival with partial cystectomy (PC) or radical cystectomy (RC), but there is an increased risk for intravesical recurrence for those treated with PC, according to research published in the October issue of The Journal of Urology.
Abiraterone Prolongs Survival in Metastatic Prostate Cancer
TUESDAY, Sept. 18 (HealthDay News) -- Abiraterone acetate significantly improves overall survival in patients with metastatic castration-resistant prostate cancer that has progressed after docetaxel treatment, according to a study published online Sept. 18 in The Lancet Oncology.
Higher Mortality Risk With Preoperative Hyponatremia
FRIDAY, Sept. 14 (HealthDay News) -- Patients with preoperative hyponatremia have a higher risk of 30-day mortality and morbidity, including coronary events, surgical site wound infections, and pneumonia, according to research published online Sept. 10 in the Archives of Internal Medicine.
Long-Term Finasteride Doesn't Impair Quality of Life
THURSDAY, Sept. 13 (HealthDay News) -- Taking finasteride to prevent prostate cancer does not negatively affect the physical function, mental health, or vitality domains of health-related quality of life, according to a study published online Sept. 12 in the Journal of the National Cancer Institute.
Thermal Sensation Spared in Nerve-Sparing Prostatectomy
THURSDAY, Sept. 13 (HealthDay News) -- Penile thermal sensory thresholds increase after non-nerve-sparing radical prostatectomy (RP) but not after the nerve-sparing procedure, according to a study published in the September issue of The Journal of Sexual Medicine.
Study Supports IL16 Role in Prostate CA in African-Americans
WEDNESDAY, Sept. 12 (HealthDay News) -- In African-Americans, IL16 polymorphisms appear to play a role in prostate cancer susceptibility, according to research published online Aug. 24 in Cancer Epidemiology, Biomarkers & Prevention.
Marijuana Use Linked to Higher Risk of Testicular Cancer
MONDAY, Sept. 10 (HealthDay News) -- Marijuana use is associated with an approximately two-fold higher risk of testicular cancer, particularly nonseminoma and mixed histology tumors, according to a study published online Sept. 10 in Cancer.
Not All Docs/Nurses Want to Be Asked About Hand Hygiene
FRIDAY, Sept. 7 (HealthDay News) -- Although most health care workers (HCWs) appreciate the role of patients in preventing health care-associated infection, a considerable proportion are uncomfortable with patients asking about their hand hygiene, according to a letter published online Sept. 3 in the Archives of Internal Medicine.
Good Long-Term Prognosis for Benign IgA Nephropathy
FRIDAY, Sept. 6 (HealthDay News) -- The long-term prognosis for Caucasian patients with immunoglobulin A (IgA) nephropathy with benign presentation (consisting of only minor urinary abnormalities and normal renal function) is excellent, without special treatment, according to research published online Sept. 6 in the Journal of the American Society of Nephrology.
Intermittent ADT Noninferior to Continuous ADT for Prostate CA
WEDNESDAY, Sept. 5 (HealthDay News) -- In men with prostate cancer who have rising prostate-specific antigen (PSA) levels after radiotherapy, overall survival is similar if they receive intermittent or continuous androgen-deprivation therapy, according to a study published in the Sept. 6 issue of the New England Journal of Medicine.
Reciprocal Increased Risk of Parkinson's, Prostate Cancer
WEDNESDAY, Sept. 5 (HealthDay News) -- Patients with Parkinson's disease (PD) have a significantly increased risk of prostate cancer and melanoma, which extends to their third-degree relatives, and there is evidence of a reciprocal risk, according to a study published online Sept. 3 in the Archives of Neurology.
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