Create Account | Sign In: Author or Forum

 
News  |  Journals  |  Conferences  |  Opinion  |  Articles  |  Forums  |  Twitter    
 
Category: Endocrinology | Family Medicine | Gastroenterology | Nursing | Pathology | Pediatrics | Journal

Back to Journal Articles

Gastro Illness in Infancy Linked to Islet Autoimmunity

Last Updated: October 12, 2012.

 

Link observed in infants exposed to wheat or barley before 4 months or ≥7 months of age

Share |

Comments: (0)

Tell-a-Friend

 

  Related
 
Gastrointestinal illnesses are associated with increased risk of islet autoimmunity among children who are exposed to wheat or barley either early or late in infancy, according to a study published online Oct. 5 in Diabetes Care.

FRIDAY, Oct. 12 (HealthDay News) -- Gastrointestinal illnesses are associated with increased risk of islet autoimmunity (IA) among children who are exposed to wheat or barley either early or late in infancy, according to a study published online Oct. 5 in Diabetes Care.

Janet K. Snell-Bergeon, Ph.D., M.P.H., from the University of Colorado Anschutz Medical Campus in Aurora, and colleagues examined the association of reported illness during infancy and later development of IA using data from illness interviews though 9 months of age, collected for 1,729 children (1,174 without a family history of type 1 diabetes and 555 children with a first-degree relative with type 1 diabetes). Having positive antibodies to insulin, glutamic acid decarboxylase, or tyrosine phosphatase on at least two consecutive study visits was defined as persistent IA.

The researchers found that 109 children had persistent IA. There was a significantly increased risk of IA associated with greater number of gastrointestinal illnesses, but only among children who were exposed to gluten-containing grains (wheat or barley) either at younger than 4 months of age (hazard ratio, 1.37) or at 7 months of age or older (hazard ratio, 1.12). Upper respiratory symptoms, respiratory illnesses, or fevers were not associated with an increased risk of IA.

"Specific pathogens such as enteroviruses or rotavirus may increase the risk of IA in the presence of existing inflammation induced by diet," Snell-Bergeon and colleagues conclude.

Abstract
Full Text (subscription or payment may be required)

Copyright © 2012 HealthDay. All rights reserved.


Previous: Patient Navigation Speeds Breast Cancer Diagnosis Next: Diabetes Independently Predicts Severe Osteoarthritis

Reader comments on this article are listed below. Review our comments policy.


Submit your opinion:

Name:

Email:

Location:

URL:

Remember my personal information

Notify me of follow-up comments?

advertisement.gif (61x7 -- 0 bytes)
 

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

Doctors Lounge Membership Application

 
     

 advertisement.gif (61x7 -- 0 bytes)

 

 

Useful Sites
MediLexicon
  Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us
Copyright © 2001-2014
Doctors Lounge.
All rights reserved.

Medical Reference:
Diseases | Symptoms
Drugs | Labs | Procedures
Software | Tutorials

Advertising
Links | Humor
Forum Archive
CME | Conferences

Privacy Statement
Terms & Conditions
Editorial Board
About us | Email

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.