October 2012 Briefing - DermatologyLast Updated: November 01, 2012.
Here are what the editors at HealthDay consider to be the most important developments in Dermatology for October 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
U.S. Medicare Spending on Elderly Has Outpaced Canada's
TUESDAY, Oct. 30 (HealthDay News) -- U.S. Medicare spending on the elderly has grown nearly three times faster than its Canadian counterpart, according to a study published online Oct. 29 in the Archives of Internal Medicine.
Negative Pigment Network Able to Distinguish Melanoma
THURSDAY, Oct. 25 (HealthDay News) -- Negative pigment network (NPN) can be used to distinguish melanoma from Spitz nevus and other benign lesions, according to a study published online Oct. 11 in the Journal of the American Academy of Dermatology.
Safety, Efficacy of At-Home Laser for Periobital Wrinkles Studied
WEDNESDAY, Oct. 24 (HealthDay News) -- A handheld nonablative fractional laser is safe and seems effective for home use for treating periorbital wrinkles, according to a study published in the November issue of the Journal of the American Academy of Dermatology.
Genuine Very Large Effects in Trials Rare in Medicine
TUESDAY, Oct. 23 (HealthDay News) -- Large treatment effects are most likely to be found in small studies, with the effect diminishing with additional trials, according to research published in the Oct. 24 issue of the Journal of the American Medical Association.
TNF Inhibitor Use Doesn't Up Short-Term Cancer Incidence
MONDAY, Oct. 22 (HealthDay News) -- Treatment of chronic immune-mediated diseases with tumor necrosis factor (TNF) inhibitors does not result in any short-term increase in cancer incidence, compared with other commonly used therapies for these conditions, according to a study published online Oct. 10 in Arthritis & Rheumatism.
Return to Work Difficult for Doctors on Sick Leave
THURSDAY, Oct. 18 (HealthDay News) -- Returning to work after a prolonged sick leave for physical or mental health problems, or drug or alcohol problems, is difficult for doctors, who describe self-stigmatization and fear a negative response on their return to work, according to a study published online Oct. 15 in BMJ Open.
Delays in Diagnosis, Variations in Treatment for Morphea
WEDNESDAY, Oct. 17 (HealthDay News) -- Patients with localized scleroderma (morphea) often experience delay in diagnosis and variability in treatment that is based more on the specialty of the provider than disease characteristics, according to a study published in the November issue of the Journal of the American Academy of Dermatology.
Filaggrin Mutations Up Risk of Irritant Contact Dermatitis
FRIDAY, Oct. 12 (HealthDay News) -- Both atopic dermatitis (AD) and loss-of-function mutations in the filaggrin gene (FLG) are independently associated with an increased risk of developing chronic irritant contact dermatitis (ICD), with people having both mutations at about a five-fold higher risk, according to research published online Oct. 5 in the British Journal of Dermatology.
Leflunomide Considered Safe, Effective for Psoriatic Arthritis
FRIDAY, Oct. 12 (HealthDay News) -- Leflunomide is effective for the treatment of patients with psoriatic arthritis (PsA) in daily clinical practice, according to a study published online Oct. 6 in Arthritis Care & Research.
Rapidly Progressive Alopecia Shows Favorable Prognosis
TUESDAY, Oct. 9 (HealthDay News) -- Patients with rapidly progressive alopecia areata (RPAA) tend to show favorable prognosis regardless of treatment selected, according to research published online Sept. 24 in the Journal of the American Academy of Dermatology.
Large Review Confirms Melanoma Risk Up in Immunosuppressed
TUESDAY, Oct. 9 (HealthDay News) -- Immunosuppressed patients, particularly solid-organ transplant recipients and lymphoma patients, have about a two-fold or higher risk of developing melanoma, according to research published in the October issue of the Mayo Clinic Proceedings.
Limiting the Problem of Missing Data Urged for Clinical Trials
WEDNESDAY, Oct. 3 (HealthDay News) -- Missing data compromise inferences from clinical trials, and due to the problematic nature of compensation with analysis methods, the importance of avoiding missing data in clinical trials is paramount, according to a special report published in the Oct. 4 issue of the New England Journal of Medicine.
Meta-Analysis Confirms Sunbed, Non-Melanoma Skin Cancer Link
WEDNESDAY, Oct. 3 (HealthDay News) -- Pooled results of multiple studies confirm that indoor tanning increases the risk of non-melanoma skin cancers, especially if tanning starts before 25 years of age, according to research published online Oct. 2 in BMJ.
Patients Benefit From Access to Physician Notes
MONDAY, Oct. 1 (HealthDay News) -- Patients report clinically relevant benefits and minimal concerns, while doctors do not experience negative consequences, from allowing patient access to visit notes, according to a study published in the Oct. 1 issue of the Annals of Internal Medicine.