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Category: Family Medicine | Monthly Briefing

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October 2012 Briefing - Family Practice

Last Updated: November 01, 2012.

 

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Here are what the editors at HealthDay consider to be the most important developments in Family Practice for October 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Once-Yearly Zoledronic Acid Benefits Men With Osteoporosis

WEDNESDAY, Oct. 31 (HealthDay News) -- For men with osteoporosis, a once-yearly infusion with zoledronic acid is associated with fewer vertebral fractures and improved bone health compared with placebo, according to a study published in the Nov. 1 issue of the New England Journal of Medicine.

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Single Topical Ivermectin Head Lice Treatment Very Effective

WEDNESDAY, Oct. 31 (HealthDay News) -- A single 10-minute, at-home treatment with topical ivermectin lotion eliminates head lice infestations in nearly all patients by the next day, according to a study published in the Nov. 1 issue of the New England Journal of Medicine.

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Greater Drop in LDL Seen With Atorvastatin + PCSK9 Antibody

WEDNESDAY, Oct. 31 (HealthDay News) -- Addition of the fully human serum proprotein convertase subtilisin/kexin 9 monoclonal antibody, SAR236553, to atorvastatin is associated with greater reductions in low-density lipoprotein (LDL) cholesterol levels compared with atorvastatin alone, according to a study published online Oct. 31 in the New England Journal of Medicine.

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FDA: Ameridose Issues Voluntary Recall of All Products

WEDNESDAY, Oct. 31 (HealthDay News) -- Ameridose, a Massachusetts-based manufacturer of sterile injectable products and oral syringes, is undergoing a voluntary recall of all unexpired products in circulation, according to an Oct. 31 news release issued by the U.S. Food and Drug Administration.

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Fenofibrate/Simvastatin Benefit in Dyslipidemia Explored

WEDNESDAY, Oct. 31 (HealthDay News) -- Combination treatment with fenofibrate and simvastatin (FENO-S) significantly reduces postprandial (PP) triglyceride (TG) levels compared with simvastatin alone in all subjects, regardless of fasting TG level, but reduces atherogenic apolipoprotein (apo) B48 particles only in those with increased fasting TG levels, according to research published online Oct. 25 in Diabetes Care.

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Latrepirdine Not Effective in Huntington's Disease

WEDNESDAY, Oct. 31 (HealthDay News) -- Although safe and well tolerated, the experimental small molecule latrepirdine does not improve cognition after six months of treatment in patients with mild-to-moderate Huntington's disease (HD), according to a study published online Oct. 29 in the Archives of Neurology.

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Risk Factors for Childhood Overweight ID'd in Infancy

WEDNESDAY, Oct. 31 (HealthDay News) -- Risk factors for childhood overweight are identifiable during infancy, and include maternal pre-pregnancy weight, infant birth weight and weight gain, and maternal smoking during pregnancy, according to research published online Oct. 29 in the Archives of Disease in Childhood.

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Genetic Marker Associated With Smoking Linked to ADHD

WEDNESDAY, Oct. 31 (HealthDay News) -- A genetic marker previously identified as associated with smoking may also be associated with attention-deficit/hyperactivity disorder (ADHD), according to a study published online Oct. 29 in the Archives of Disease in Childhood.

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Only Omega-3s From Fish Tied to Lower Cerebrovascular Risk

WEDNESDAY, Oct. 31 (HealthDay News) -- Intake of omega-3 fatty acids from fish, but not circulating biomarkers or supplements, correlates with modestly reduced cerebrovascular risk, according to a meta-analysis published online Oct. 30 in BMJ.

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Smoke-Free Workplace Laws Lead to Decline in MI Incidence

WEDNESDAY, Oct. 31 (HealthDay News) -- Following implementation of workplace smoke-free laws, the incidence of myocardial infarction (MI) decreased significantly in Olmsted County, Minn., according to a study published online Oct. 29 in the Archives of Internal Medicine.

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Early Behavioral Intervention 'Normalizes' Brain Pattern in ASD

WEDNESDAY, Oct. 31 (HealthDay News) -- For young children with autism spectrum disorder (ASD), early behavioral intervention is associated with normalized brain activity patterns, which correlate with improvements in social behavior, according to research published in the November issue of the Journal of the American Academy of Child & Adolescent Psychiatry.

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Total Bilirubin Predicts In-Hospital Mortality in STEMI

TUESDAY, Oct. 30 (HealthDay News) -- For patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI), serum total bilirubin (TB) levels can be used to predict the risk of in-hospital mortality, according to a study published online Oct. 26 in The American Journal of Cardiology.

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Quality of Life for Cancer Survivors Depends on Type

TUESDAY, Oct. 30 (HealthDay News) -- Survivors of cancers are more likely to report poor physical and mental health-related quality of life (HRQOL), compared with adults without cancer, with considerable variation noted for different types of cancers, according to a study published online Oct. 30 in Cancer Epidemiology, Biomarkers & Prevention.

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Children With Autism Have Normal Development at 6 Months

TUESDAY, Oct. 30 (HealthDay News) -- The development of children with autism spectrum disorder (ASD) is similar to children without the disorder at 6 months of age, suggesting that ASD has a pre-clinical phase of varying duration when detection may be difficult, according to a study published online Oct. 30 in Child Development.

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U.S. Medicare Spending on Elderly Has Outpaced Canada's

TUESDAY, Oct. 30 (HealthDay News) -- U.S. Medicare spending on the elderly has grown nearly three times faster than its Canadian counterpart, according to a study published online Oct. 29 in the Archives of Internal Medicine.

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Overweight, Obese Teens at Risk for End-Stage Renal Disease

TUESDAY, Oct. 30 (HealthDay News) -- Being overweight or obese as an adolescent is significantly associated with increased risk for all-cause treated end-stage renal disease (ESRD), according to a study published online Oct. 29 in the Archives of Internal Medicine.

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Resveratrol Has No Metabolic Benefit for Non-Obese Women

TUESDAY, Oct. 30 (HealthDay News) -- Resveratrol supplementation does not improve plasma lipids or insulin sensitivity in non-obese women, nor does it affect its putative targets in fat or muscle, according to a study published online Oct. 25 in Cell Metabolism.

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ApoE ε3 Is Most Common ApoE Among Oldest Old

TUESDAY, Oct. 30 (HealthDay News) -- Most nonagenarians carry the ApoE ε3 genotype and few carry the ApoE ε4 genotype, with no association noted between the ApoE ε4 allele and quality of life (QOL), according to a study published in the October issue of the Journal of the American Medical Directors Association.

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Acupuncture Reduces Breast Cancer-Related Fatigue

MONDAY, Oct. 29 (HealthDay News) -- Acupuncture significantly reduces fatigue and improves quality of life in breast cancer patients with cancer-related fatigue, according to a study published online Oct. 29 in the Journal of Clinical Oncology.

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Children With Migraine at Risk for Poor School Performance

MONDAY, Oct. 29 (HealthDay News) -- Children with migraine are significantly more likely to have poor performance at school, according to a study published in the Oct. 30 issue of Neurology.

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Smoke-Free Laws Linked to Fewer Hospital Admissions

MONDAY, Oct. 29 (HealthDay News) -- Comprehensive smoke-free legislation is associated with decreases in hospital admissions for cardiovascular and respiratory disease, according to a meta-analysis published in the Oct. 30 issue of Circulation.

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Buspirone Improves Symptoms in Functional Dyspepsia

MONDAY, Oct. 29 (HealthDay News) -- Buspirone, a 5-hydroxytryptamine 1A receptor agonist, improves symptom severity in patients with functional dyspepsia (FD), according to a proof-of-concept study published in the November issue of Clinical Gastroenterology and Hepatology.

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Burden of Gastrointestinal Disease in U.S. Substantial

MONDAY, Oct. 29 (HealthDay News) -- Gastrointestinal diseases account for substantial morbidity, mortality, and cost in the United States, according to research published in the November issue of Gastroenterology.

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Pediatricians Key in Rural Emergency Medical Services

MONDAY, Oct. 29 (HealthDay News) -- In rural areas, pediatricians can play a key role in the development, implementation, and ongoing supervision of emergency medical services for children (EMSC), according to a policy statement from the American Academy of Pediatrics (AAP) published online Oct. 29 in Pediatrics.

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Hypnosis Cuts Hot Flashes in Postmenopausal Women

MONDAY, Oct. 29 (HealthDay News) -- For postmenopausal women, clinical hypnosis is associated with significant reductions in self-reported and physiologically measured hot flashes, according to a study published online Oct. 22 in Menopause.

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Old Order Amish Children More Active, Less Likely Overweight

MONDAY, Oct. 29 (HealthDay News) -- Old Order Amish (OOA) children are less likely to be overweight and are more physically active than other children, according to a study published online Oct. 23 in Diabetes Care.

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Quitting Before 40 Avoids Most Excess Smoking-Linked Mortality

MONDAY, Oct. 29 (HealthDay News) -- For U.K. women, the hazards of smoking and benefits of quitting are considerable, with women who quit before age 30 avoiding more than 97 percent of excess smoking-related mortality, according to a study published online Oct. 27 in The Lancet.

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Systematic Pain Management Needed for Children in ER

MONDAY, Oct. 29 (HealthDay News) -- Steps to manage pain and stress in pediatric emergency medical care are recommended, according to a clinical report from the American Academy of Pediatrics (AAP) published online Oct. 29 in Pediatrics.

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Brain Volume Rebounds Within Days of Alcohol Abstinence

FRIDAY, Oct. 26 (HealthDay News) -- Gray matter (GM) volume in the brains of alcohol-dependent patients begins to recover within days of alcohol abstinence, according to a study published online Oct. 16 in Alcoholism: Clinical & Experimental Research.

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Impact of Partial Sleep Deprivation on Weight Explored

FRIDAY, Oct. 26 (HealthDay News) -- Various mechanisms may be involved in the correlation between sleep deprivation and obesity, including disruption of appetitive hormones and influence on energy intake, according to research published in the November issue of the Journal of the Academy of Nutrition and Dietetics.

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Independent Link for Child BMI, Adult Cardio Risk Questioned

FRIDAY, Oct. 26 (HealthDay News) -- Although the evidence for an association between childhood body mass index (BMI) and cardiovascular outcomes seems consistent, few studies examine this association independent of adult BMI, according to research published in the November issue of Obesity Reviews.

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Prevalence, Risks for Sexual Dysfunction Vary by Veteran Age

FRIDAY, Oct. 26 (HealthDay News) -- For Iraq/Afghanistan veterans, the prevalence and risk factors for sexual dysfunction (SD) vary with age, according to a study published online Oct. 22 in The Journal of Sexual Medicine.

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High Costs for Early Retirement Due to Spinal Disorders

FRIDAY, Oct. 26 (HealthDay News) -- Spinal disorders that trigger early retirement have a significant impact on labor force participation and the gross domestic product (GDP) in Australia, according to a study published online Oct. 22 in The Spine Journal.

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Insulin Sensitivity Normally Highest After Breakfast

FRIDAY, Oct. 26 (HealthDay News) -- In healthy people without diabetes, glucose responsiveness tends to be higher after breakfast, which may have implications for the design of closed-loop insulin delivery systems for diabetes patients, according to a study published in the November issue of Diabetes.

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Incidence of Recurrent Anal Sphincter Rupture ~7 Percent

FRIDAY, Oct. 26 (HealthDay News) -- The incidence of recurrent anal sphincter rupture (ASR) is 7.1 percent, and several risk factors are associated with an increased risk, including excessive birth weight, vacuum extraction, and shoulder dystocia, according to research published online Oct. 19 in BJOG: An International Journal of Obstetrics and Gynaecology.

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High Reliability for Hypersexual Disorder Diagnostic Criteria

FRIDAY, Oct. 26 (HealthDay News) -- Proposed criteria for hypersexual disorder (HD) show high reliability and validity, according to results of a field trial conducted by the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) Work Group on Sexual and Gender Identity Disorders, published online Oct. 4 in The Journal of Sexual Medicine.

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Sleep Apnea Linked to Less Severe Injury During Acute MI

THURSDAY, Oct. 25 (HealthDay News) -- During an acute non-fatal myocardial infarction (MI), patients with obstructive sleep apnea (OSA) have less severe cardiac injury, according to a study published in the October issue of Sleep and Breathing.

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Study Confirms Stroke Survivors Continuing to Smoke Fare Worse

THURSDAY, Oct. 25 (HealthDay News) -- Stroke patients who are current or ex-smokers are at greater risk of death or another stroke or heart attack than stroke patients who never smoked, though the risk in ex-smokers is smaller, according to a study published online Oct. 25 in Stroke.

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Surgery Center Influences Outcomes in Spinal Surgery

THURSDAY, Oct. 25 (HealthDay News) -- Choice of surgery center affects patient outcomes following surgery for lumbar stenosis and degenerative spondylolisthesis, according to research published online Oct. 17 in Spine.

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Timing of Hormone Therapy Use Impacts Alzheimer's Risk

THURSDAY, Oct. 25 (HealthDay News) -- Use of hormone therapy (HT) within five years of menopause is associated with a reduction in the risk of Alzheimer's disease (AD), according to a study published online Oct. 24 in Neurology.

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Meta-Analysis: Antivirals Reduce Risk of Liver Cancer in Hep C

THURSDAY, Oct. 25 (HealthDay News) -- Antiviral treatment does significantly reduce the risk of developing liver cancer for patients with chronic hepatitis C infection, particularly in virological responders, according to a meta-analysis published online Oct. 22 in BMJ Open.

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Bystander CPR More Likely in High-Income White Neighborhoods

THURSDAY, Oct. 25 (HealthDay News) -- Bystanders are more likely to initiate cardiopulmonary resuscitation (CPR) on patients who have a cardiac arrest in high-income white neighborhoods, according to a study published in the Oct. 25 issue of the New England Journal of Medicine.

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Link Between Vitamin D, Mortality Not Impacted by eGFR

THURSDAY, Oct. 25 (HealthDay News) -- Adults with low levels of 25-hydroxyvitamin D (25[OH]D) have increased mortality, regardless of the presence of estimated glomerular filtration rate (eGFR) of <60 ml/min/1.73 m², according to a study published online Oct. 24 in PLoS One.

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A-Fib Burden Similar With Ablation, Antiarrhythmic Meds

WEDNESDAY, Oct. 24 (HealthDay News) -- For patients with paroxysmal atrial fibrillation with no history of antiarrhythmic drug use, there is no significant difference in the cumulative burden of atrial fibrillation over two years between the treatment strategies of radiofrequency catheter ablation or antiarrhythmic agents, according to a study published in the Oct. 25 issue of the New England Journal of Medicine.

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Terminal Cancer Patients May Have Erroneous Chemo Beliefs

WEDNESDAY, Oct. 24 (HealthDay News) -- Patients with stage IV metastatic cancer frequently do not understand that chemotherapy is unlikely to be curative, according to a study published in the Oct. 25 issue of the New England Journal of Medicine.

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Better Obesity Risk Prediction With Hip and Waist Measures

WEDNESDAY, Oct. 24 (HealthDay News) -- Inclusion of both waist and hip circumference as separate anthropometric measurements may improve risk prediction for obesity-related mortality and morbidity, according to research published online Oct. 17 in Obesity Reviews.

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Decrease in CRC Resections Tied to Medicare-Covered Screening

WEDNESDAY, Oct. 24 (HealthDay News) -- The rates of resection for distal and proximal colorectal cancer (CRC) decreased from 1993 to 2009, with rates of proximal resection decreasing significantly from 2002, after implementation of Medicare payment for screening colonoscopy, according to a study published in the November issue of Gastroenterology.

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Exercise Cuts Atrophy, White Matter Lesion Load in Elderly

WEDNESDAY, Oct. 24 (HealthDay News) -- In older adults, physical activity is associated with less brain atrophy and white matter lesion (WML) load, according to a study published in the Oct. 23 issue of Neurology.

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Risk of Suicide Ideation Up for Recently Victimized Teens

WEDNESDAY, Oct. 24 (HealthDay News) -- Adolescents exposed to recent victimization have an increased risk for suicide ideation, with a higher risk for those exposed to polyvictimization, according to a study published online Oct. 22 in the Archives of Pediatrics & Adolescent Medicine.

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Safety, Efficacy of At-Home Laser for Periobital Wrinkles Studied

WEDNESDAY, Oct. 24 (HealthDay News) -- A handheld nonablative fractional laser is safe and seems effective for home use for treating periorbital wrinkles, according to a study published in the November issue of the Journal of the American Academy of Dermatology.

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Hormonal Changes at Menopause Up Abdominal Obesity

WEDNESDAY, Oct. 24 (HealthDay News) -- The increase in total body fat and abdominal fat seen at menopause is due to the hormonal changes taking place, which can be improved by estrogen treatment, according to a study published in the October issue of Climacteric.

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Family Obesity Approach Promising for Black Girls

WEDNESDAY, Oct. 24 (HealthDay News) -- Obesity interventions that include family involvement may be a promising approach for targeting African-American girls, but more research is required, according to the results of a systematic literature review published online Oct. 12 in Obesity Reviews.

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Single Bout of Exercise Benefits Children With ADHD

WEDNESDAY, Oct. 24 (HealthDay News) -- A single bout of moderate intensity aerobic exercise may improve neurocognitive function and inhibitory control for children with attention-deficit/hyperactivity disorder (ADHD), according to a study published online Oct. 19 in The Journal of Pediatrics.

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Genuine Very Large Effects in Trials Rare in Medicine

TUESDAY, Oct. 23 (HealthDay News) -- Large treatment effects are most likely to be found in small studies, with the effect diminishing with additional trials, according to research published in the Oct. 24 issue of the Journal of the American Medical Association.

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Four Factors Account for Most of Risk Linked to PAD in Men

TUESDAY, Oct. 23 (HealthDay News) -- Smoking, hypertension, high cholesterol, and type 2 diabetes account for most of the risk for developing peripheral artery disease (PAD) among men, according to a study published in the Oct. 24 issue of the Journal of the American Medical Association.

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Legume-Rich Diet Can Improve Glycemic Control in T2DM

TUESDAY, Oct. 23 (HealthDay News) -- For individuals with type 2 diabetes mellitus, consumption of a low glycemic index (GI) diet incorporating legumes is associated with improved glycemic control and a reduction in the risk of coronary heart disease, according to a study published online Oct. 22 in the Archives of Internal Medicine.

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Antihypertensive Medication Use, BP Control Up in U.S.

TUESDAY, Oct. 23 (HealthDay News) -- Antihypertensive medication use and blood pressure control are increasing among U.S. adults, but racial disparities still exist, according to a study published in the Oct. 23 issue of Circulation.

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Guidelines Stretch Interval for Cervical Cancer Screening

TUESDAY, Oct. 23 (HealthDay News) -- Cervical cancer screening should be performed every three to five years, according to the new Clinical Management Guideline published in the November issue of Obstetrics & Gynecology.

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Genetic Predisposition to Diabetes Ups Risk of CVD

TUESDAY, Oct. 23 (HealthDay News) -- For patients with type 2 diabetes (T2D), having a genetic predisposition towards the disease is associated with an increased risk of cardiovascular disease (CVD), according to a study published online Oct. 15 in Diabetes Care.

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HRT Not Recommended for Prevention of Chronic Conditions

MONDAY, Oct. 22 (HealthDay News) -- The benefits of hormone replacement therapy to prevent chronic conditions in postmenopausal women do not outweigh the harms, according to a recommendation statement from the U.S. Preventive Services Task Force (USPSTF) published online Oct. 23 in the Annals of Internal Medicine.

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TNF Inhibitor Use Doesn't Up Short-Term Cancer Incidence

MONDAY, Oct. 22 (HealthDay News) -- Treatment of chronic immune-mediated diseases with tumor necrosis factor (TNF) inhibitors does not result in any short-term increase in cancer incidence, compared with other commonly used therapies for these conditions, according to a study published online Oct. 10 in Arthritis & Rheumatism.

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Lower Extremity Pain Negatively Impacts Obese Children

MONDAY, Oct. 22 (HealthDay News) -- Obese children with lower extremity (LE) pain have worse physical function and poorer psychosocial health compared to those without LE pain, according to a study published online Oct. 12 in Clinical Orthopaedics and Related Research.

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Obese Young Males Have Lower Testosterone Levels

MONDAY, Oct. 22 (HealthDay News) -- Obesity in young males is associated with low testosterone concentrations, according to a study published online Sept. 13 in Clinical Endocrinology.

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Parental Stress Linked to Obesity in Offspring

MONDAY, Oct. 22 (HealthDay News) -- The number of parent stressors is associated with child obesity, and parent-perceived stress impacts related behaviors, specifically fast-food consumption, according to a study published online Oct. 22 in Pediatrics.

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Effects of Bariatric Surgery on Heart Function, Structure ID'd

MONDAY, Oct. 22 (HealthDay News) -- Bariatric surgery is associated with improvement or resolution of preexisting hypertension, hyperlipidemia, and diabetes in a majority of participants, as well as with improvements in left ventricular hypertrophy and diastolic function, according to research published online Oct. 17 in Heart.

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Metabolic Factors Impact Risk of Death From Prostate Cancer

MONDAY, Oct. 22 (HealthDay News) -- Metabolic factors are not associated with the risk of prostate cancer, but high levels are associated with increased risk of death from prostate cancer, according to research published online Oct. 22 in Cancer.

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Anergia Prevalent in Acute Coronary Syndrome Patients

FRIDAY, Oct. 19 (HealthDay News) -- Anergia, or the lack of energy, is highly prevalent in patients with acute coronary syndromes (ACS), and correlates independently with several factors, including bodily pain and exercise participation, according to a study published in the Nov. 1 issue of The American Journal of Cardiology.

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Increased Human Life Expectancy Relatively Recent

FRIDAY, Oct. 19 (HealthDay News) -- Most of the increase in human life expectancy has occurred in the last four generations, out of the roughly 8,000 generations that have ever lived, according to a study published online Oct. 15 in the Proceedings of the National Academy of Sciences.

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Sedentary Time Linked to Increased Diabetes Risk

FRIDAY, Oct. 19 (HealthDay News) -- Greater sedentary time is associated with increased risk of diabetes, cardiovascular disease, and cardiovascular and all-cause mortality, with the most consistent associations seen for diabetes, according to a review and meta-analysis published in the November issue of Diabetologia.

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Common Liver Tests Can Predict Liver Cancer Risk

FRIDAY, Oct. 19 (HealthDay News) -- Common liver function tests, including measurement of alanine transaminase (ALT) and aspartate transaminase (AST) levels, can be used to reliably predict hepatocellular carcinoma (HCC) risk in the general population with average or unknown risk, according to research published in the Oct. 17 issue of the Journal of the National Cancer Institute.

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Social Outcomes Good for Most Pediatric Brain Tumor Survivors

FRIDAY, Oct. 19 (HealthDay News) -- While the majority of survivors of pediatric embryonal tumors display positive social outcomes several years after diagnosis and treatment, specific risk factors may affect social adjustment and behavior over the long term, according to research published online Oct. 15 in the Journal of Clinical Oncology.

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Children With Autism Lack Language to Explain Behavior

FRIDAY, Oct. 19 (HealthDay News) -- Unlike typically developing children, children with autism do not use language areas of the brain to identify socially inappropriate behavior, according to a study published online Oct. 17 in PLoS One.

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Higher Calcium Intake May Lower Risk of Hyperparathyroidism

FRIDAY, Oct. 19 (HealthDay News) -- Women consuming higher levels of calcium are at lower risk of primary hyperparathyroidism, according to a study published online Oct. 18 in BMJ.

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CDC: Unintentional Injury Greatest Childhood Killer in U.S.

THURSDAY, Oct. 18 (HealthDay News) -- Between 2000 and 2009, more than 115,000 young people in the United States lost their lives to unintentional injury, the leading cause of death among people 0 to 19 years of age in the United States, according to research published in the Oct. 19 issue of the U.S. Centers for Disease Control and Prevention's Morbidity & Mortality Weekly Report.

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In Depression, Discrimination Has Adverse Social Impact

THURSDAY, Oct. 18 (HealthDay News) -- For individuals with major depressive disorder, discrimination adversely affects social participation and vocational integration, according to a study published online Oct. 18 in The Lancet.

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Treating Obstructive Sleep Apnea Tied to Lasting BP Drop

THURSDAY, Oct. 18 (HealthDay News) -- In men with obstructive sleep apnea (OSA) and preexisting systemic hypertension or type 2 diabetes, positive airway pressure (PAP) is associated with a significant and sustained reduction in both systolic and diastolic blood pressure (BP), according to research published in the Oct. 15 issue of the Journal of Clinical Sleep Medicine.

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Return to Work Difficult for Doctors on Sick Leave

THURSDAY, Oct. 18 (HealthDay News) -- Returning to work after a prolonged sick leave for physical or mental health problems, or drug or alcohol problems, is difficult for doctors, who describe self-stigmatization and fear a negative response on their return to work, according to a study published online Oct. 15 in BMJ Open.

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Exercise Stimulates Adiponectin, Raises HDL Levels

THURSDAY, Oct. 18 (HealthDay News) -- Intensive lifestyle intervention for weight loss (ILI) significantly improves high-density lipoprotein cholesterol (HDL-C) levels in overweight and obese individuals with type 2 diabetes, which is partially mediated by stimulation of adiponectin production, according to a study published online Sept. 5 in the Journal of Lipid Research.

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Post-Bleed Hydrocephalus Risk Up in Low-Income Preemies

THURSDAY, Oct. 18 (HealthDay News) -- Preterm neonates born to low-income parents have a disproportionately high risk of developing posthemorrhagic hydrocephalus (PHH) that requires multiple surgeries and extensive follow-up, according to research published online Sept. 28 in Pediatric Neurosurgery.

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Stroke Risk Up With Serotonin Reuptake Inhibitor Use

THURSDAY, Oct. 18 (HealthDay News) -- Exposure to selective serotonin reuptake inhibitors (SSRIs) is associated with an increased risk of intracerebral and intracranial hemorrhage, according to a study published online Oct. 17 in Neurology.

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Alzheimer's Symptoms Relapse Risk High After Halting Drug

WEDNESDAY, Oct. 17 (HealthDay News) -- Patients with Alzheimer's disease and psychosis or agitation-aggression who initially respond to antipsychotic drugs are more likely to relapse if treatment is discontinued, according to a study published in the Oct. 18 issue of the New England Journal of Medicine.

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Video Identifies Cause of Falls Among Elderly in Care Facilities

WEDNESDAY, Oct. 17 (HealthDay News) -- Video evidence has identified the most frequent causes of falls and the activities that are most commonly associated with falling among the elderly in long-term care facilities, according to a study published online Oct. 17 in The Lancet.

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Women With RA Report Lower Sexual Function

WEDNESDAY, Oct. 17 (HealthDay News) -- Rheumatoid arthritis (RA) has negative effects on sexual function in women, with depressive symptoms and disease severity linked to the degree of sexual dysfunction, according to a study published in the October issue of The Journal of Sexual Medicine.

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Criteria Variable for Concussion Diagnosis in College Athletes

WEDNESDAY, Oct. 17 (HealthDay News) -- For college athletes, diagnosed concussions are associated with a specific contact event about two-thirds of the time, and diagnosis is often based on self-reported symptoms after a variable delay, according to a study published online Oct. 2 in the Journal of Neurosurgery.

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Excess Mortality for Alcohol-Dependent, Especially Women

WEDNESDAY, Oct. 17 (HealthDay News) -- Alcohol-dependent adults, particularly women, have excess mortality, according to a study published online Oct. 16 in Alcoholism: Clinical & Experimental Research.

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Lipid Profiles Improved in Past Two Decades in United States

TUESDAY, Oct. 16 (HealthDay News) -- Since 1988, levels of cholesterol and related lipids have been moving in a favorable direction among adults in the United States, even among the obese and those not taking lipid-lowering drugs, according to a study published in the Oct. 17 issue of the Journal of the American Medical Association.

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High-Dose Vitamins Don't Halt HIV Progression, Death

TUESDAY, Oct. 16 (HealthDay News) -- High-dose vitamin supplementation does not reduce HIV disease progression or death among HIV patients initiating highly active antiretroviral therapy (HAART) in Tanzania, according to a study published in the Oct. 17 issue of the Journal of the American Medical Association.

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β-Amyloid Load Linked to Decline in Memory for Elderly

TUESDAY, Oct. 16 (HealthDay News) -- Elevated cerebral β-amyloid (Aβ) load is associated with greater decline in episodic and working memory for healthy and cognitively normal older adults over an 18-month period, with a larger effect than that seen for the APOE ε4 allele, according to research published in the Oct. 16 issue of Neurology.

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Electronic Health Records Improve Ambulatory Care

TUESDAY, Oct. 16 (HealthDay News) -- The use of electronic health records (EHRs) significantly improves the quality of ambulatory care in a community-based setting, according to a study published online Oct. 3 in the Journal of General Internal Medicine.

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About 170 Million Healthy Life-Years Lost to Cancer Globally

TUESDAY, Oct. 16 (HealthDay News) -- The age-adjusted disability-adjusted life-years (DALYs) lost from cancer are considerable, with 169.3 million years of healthy life lost globally in 2008, according to a study published online Oct. 16 in The Lancet.

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Direct Link ID'd for Sleep Deprivation, Insulin Sensitivity

TUESDAY, Oct. 16 (HealthDay News) -- Even short-term sleep restriction results in an insulin-resistant state in adipocytes, according to research published in the Oct. 16 issue of the Annals of Internal Medicine.

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Case Series Suggest 'Mother's Kiss' Is Safe, Effective

TUESDAY, Oct. 16 (HealthDay News) -- A technique known as "mother's kiss" is safe and generally effective for removing foreign objects from children's noses, according to a review published online Oct. 15 in CMAJ, the journal of the Canadian Medical Association.

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Increased Substance Use Seen After Weight Loss Surgery

TUESDAY, Oct. 16 (HealthDay News) -- Patients who undergo weight loss surgery may have an increased risk for substance use after surgery, according to a study published online Oct. 15 in the Archives of Surgery.

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Recent Drop in Post-Discharge Mortality After Acute MI

TUESDAY, Oct. 16 (HealthDay News) -- For patients with acute myocardial infarction (AMI), post-discharge mortality rates decreased from 2001 to 2007, according to a study published in the Oct. 15 issue of The American Journal of Cardiology.

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Psychopathological Sequelae of ADHD Extend to Adulthood

MONDAY, Oct. 15 (HealthDay News) -- For children with attention-deficit/hyperactivity disorder (ADHD) without conduct disorders, the psychopathological consequences extend into adulthood, although most of these consequences begin in adolescence, according to a study published online Oct. 15 in the Archives of General Psychiatry.

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Zonisamide 400 mg Enhances Weight Loss for Obese

MONDAY, Oct. 15 (HealthDay News) -- The antiepileptic drug zonisamide, at a dosage of 400 mg per day, is associated with enhanced weight loss for obese patients when combined with diet and lifestyle counseling, but the incidence of adverse events is high, according to a study published online Oct. 15 in the Archives of Internal Medicine.

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Patellofemoral Disease Features Analyzed in Osteoarthritis

MONDAY, Oct. 15 (HealthDay News) -- For patients with osteoarthritis (OA), knees affected by more severe patellofemoral (PF) disease have distinct features from those of patients with tibiofemoral (TF) OA

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