Here are what the editors at HealthDay consider to be the most important developments in OBGYN & Women's Health for October 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Risk Factors for Childhood Overweight ID'd in Infancy
WEDNESDAY, Oct. 31 (HealthDay News) -- Risk factors for childhood overweight are identifiable during infancy, and include maternal pre-pregnancy weight, infant birth weight and weight gain, and maternal smoking during pregnancy, according to research published online Oct. 29 in the Archives of Disease in Childhood.
Fertility-Sparing Tx Feasible in Early Endometrial Cancer
TUESDAY, Oct. 30 (HealthDay News) -- For women with early-stage endometrial cancer (EC) and atypical complex hyperplasia (ACH), fertility-sparing treatment seems feasible, according to research published in the October issue of the American Journal of Obstetrics & Gynecology.
Resveratrol Has No Metabolic Benefit for Non-Obese Women
TUESDAY, Oct. 30 (HealthDay News) -- Resveratrol supplementation does not improve plasma lipids or insulin sensitivity in non-obese women, nor does it affect its putative targets in fat or muscle, according to a study published online Oct. 25 in Cell Metabolism.
U.S. Medicare Spending on Elderly Has Outpaced Canada's
TUESDAY, Oct. 30 (HealthDay News) -- U.S. Medicare spending on the elderly has grown nearly three times faster than its Canadian counterpart, according to a study published online Oct. 29 in the Archives of Internal Medicine.
Adverse Prognostic Factor ID'd in Operable Breast Cancer
TUESDAY, Oct. 30 (HealthDay News) -- For women with operable breast cancer, moderate immunohistochemical expression of human epidermal growth factor receptor (HER)-2 (2+) without amplification of HER-2 (HER-2 2+/HER-2−) is an adverse prognostic factor, according to a study published online Sept. 4 in The Oncologist.
Acupuncture Reduces Breast Cancer-Related Fatigue
MONDAY, Oct. 29 (HealthDay News) -- Acupuncture significantly reduces fatigue and improves quality of life in breast cancer patients with cancer-related fatigue, according to a study published online Oct. 29 in the Journal of Clinical Oncology.
Hypnosis Cuts Hot Flashes in Postmenopausal Women
MONDAY, Oct. 29 (HealthDay News) -- For postmenopausal women, clinical hypnosis is associated with significant reductions in self-reported and physiologically measured hot flashes, according to a study published online Oct. 22 in Menopause.
Quitting Before 40 Avoids Most Excess Smoking-Linked Mortality
MONDAY, Oct. 29 (HealthDay News) -- For U.K. women, the hazards of smoking and benefits of quitting are considerable, with women who quit before age 30 avoiding more than 97 percent of excess smoking-related mortality, according to a study published online Oct. 27 in The Lancet.
Considerable Regional Variation for Brachytherapy
FRIDAY, Oct. 26 (HealthDay News) -- A considerable proportion of Medicare beneficiaries are treated with brachytherapy for breast cancer, with substantial regional variation, according to a study published online Oct. 22 in the Journal of Clinical Oncology.
High Reliability for Hypersexual Disorder Diagnostic Criteria
FRIDAY, Oct. 26 (HealthDay News) -- Proposed criteria for hypersexual disorder (HD) show high reliability and validity, according to results of a field trial conducted by the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) Work Group on Sexual and Gender Identity Disorders, published online Oct. 4 in The Journal of Sexual Medicine.
Incidence of Recurrent Anal Sphincter Rupture ~7 Percent
FRIDAY, Oct. 26 (HealthDay News) -- The incidence of recurrent anal sphincter rupture (ASR) is 7.1 percent, and several risk factors are associated with an increased risk, including excessive birth weight, vacuum extraction, and shoulder dystocia, according to research published online Oct. 19 in BJOG: An International Journal of Obstetrics and Gynaecology.
Timing of Hormone Therapy Use Impacts Alzheimer's Risk
THURSDAY, Oct. 25 (HealthDay News) -- Use of hormone therapy (HT) within five years of menopause is associated with a reduction in the risk of Alzheimer's disease (AD), according to a study published online Oct. 24 in Neurology.
Worse Outcomes for Mother-Infant Pairs in Separate ICUs
WEDNESDAY, Oct. 24 (HealthDay News) -- Concurrent admission of a mother and her newborn to separate intensive care units (co-ICU) is associated with increased prevalence of mother-infant separation because of interfacility transfer, and with elevated mortality for both, according to a study published online Oct. 22 in CMAJ, the journal of the Canadian Medical Association.
Family Obesity Approach Promising for Black Girls
WEDNESDAY, Oct. 24 (HealthDay News) -- Obesity interventions that include family involvement may be a promising approach for targeting African-American girls, but more research is required, according to the results of a systematic literature review published online Oct. 12 in Obesity Reviews.
Hormonal Changes at Menopause Up Abdominal Obesity
WEDNESDAY, Oct. 24 (HealthDay News) -- The increase in total body fat and abdominal fat seen at menopause is due to the hormonal changes taking place, which can be improved by estrogen treatment, according to a study published in the October issue of Climacteric.
Genuine Very Large Effects in Trials Rare in Medicine
TUESDAY, Oct. 23 (HealthDay News) -- Large treatment effects are most likely to be found in small studies, with the effect diminishing with additional trials, according to research published in the Oct. 24 issue of the Journal of the American Medical Association.
New Scan Feasible for 3D Diagnosis of Breast Cancer
TUESDAY, Oct. 23 (HealthDay News) -- A high-resolution, low-dose phase contrast X-ray tomographic method of three-dimensional (3D) diagnosis, using an image reconstruction method known as equally sloped tomography, can be used to identify malignant breast cancer at clinically compatible doses of radiation, according to research published online Oct. 22 in the Proceedings of the National Academy of Sciences.
Guidelines Stretch Interval for Cervical Cancer Screening
TUESDAY, Oct. 23 (HealthDay News) -- Cervical cancer screening should be performed every three to five years, according to the new Clinical Management Guideline published in the November issue of Obstetrics & Gynecology.
HRT Not Recommended for Prevention of Chronic Conditions
MONDAY, Oct. 22 (HealthDay News) -- The benefits of hormone replacement therapy to prevent chronic conditions in postmenopausal women do not outweigh the harms, according to a recommendation statement from the U.S. Preventive Services Task Force (USPSTF) published online Oct. 23 in the Annals of Internal Medicine.
Sling Offers Lasting Benefit for Stress Urinary Incontinence
MONDAY, Oct. 22 (HealthDay News) -- Stress urinary incontinence treatment with a distal urethral polypropylene sling procedure is associated with excellent long-term efficacy and durability, according to research published in the November issue of The Journal of Urology.
Higher Calcium Intake May Lower Risk of Hyperparathyroidism
FRIDAY, Oct. 19 (HealthDay News) -- Women consuming higher levels of calcium are at lower risk of primary hyperparathyroidism, according to a study published online Oct. 18 in BMJ.
Return to Work Difficult for Doctors on Sick Leave
THURSDAY, Oct. 18 (HealthDay News) -- Returning to work after a prolonged sick leave for physical or mental health problems, or drug or alcohol problems, is difficult for doctors, who describe self-stigmatization and fear a negative response on their return to work, according to a study published online Oct. 15 in BMJ Open.
Vaccination Strategy Effective Against Genital Herpes
THURSDAY, Oct. 18 (HealthDay News) -- A new vaccination strategy is effective against genital herpes and possibly other sexually transmitted infections, according to an experimental study published online Oct. 17 in Nature.
Women With RA Report Lower Sexual Function
WEDNESDAY, Oct. 17 (HealthDay News) -- Rheumatoid arthritis (RA) has negative effects on sexual function in women, with depressive symptoms and disease severity linked to the degree of sexual dysfunction, according to a study published in the October issue of The Journal of Sexual Medicine.
Excess Mortality for Alcohol-Dependent, Especially Women
WEDNESDAY, Oct. 17 (HealthDay News) -- Alcohol-dependent adults, particularly women, have excess mortality, according to a study published online Oct. 16 in Alcoholism: Clinical & Experimental Research.
HPV Vaccination Doesn't Up Poor Outcomes for Sexual Activity
MONDAY, Oct. 15 (HealthDay News) -- For girls, receipt of human papillomavirus (HPV) vaccination at the recommended ages (11 to 12 years) does not correlate with an increase in sexual activity-related outcomes, according to a study published online Oct. 15 in Pediatrics.
Patient Navigation Speeds Breast Cancer Diagnosis
FRIDAY, Oct. 12 (HealthDay News) -- Patient navigation -- a service that helps patients navigate the health care system, including setting up appointments, dealing with health insurance, and coping with fears about cancer -- leads to quicker breast cancer diagnosis, especially for women requiring biopsy, according to a study published in the October issue of Cancer Epidemiology, Biomarkers & Prevention.
Social Media Influences Youth Sexual Behavior in Short Term
THURSDAY, Oct. 11 (HealthDay News) -- Social media can be an efficacious vehicle for delivering messages regarding the prevention of sexually transmitted infections (STIs), according to a study published online Oct. 9 in the American Journal of Preventive Medicine.
Study Confirms Link Between Analgesic Use, Ovarian Cancer
THURSDAY, Oct. 11 (HealthDay News) -- Use of any analgesic or aspirin correlates with a reduced risk of ovarian cancer, with the reduction significant only for use of any analgesic and serous ovarian cancer, according to a case-control study published in the September issue of ACTA Obstetricia et Gynecologica Scandinavica.
Interventions Helpful for Breast Cancer-Induced Menopause
THURSDAY, Oct. 11 (HealthDay News) -- Cognitive behavioral therapy (CBT) and physical exercise improve endocrine and urinary symptoms as well as physical functioning in patients with breast cancer treatment-induced menopause, according to research published online Oct. 8 in the Journal of Clinical Oncology.
New Cervical Cancer Vaccine Targets HPV-Infected Women
WEDNESDAY, Oct. 10 (HealthDay News) -- A new candidate vaccine designed to prevent cervical dysplasia and cancer in women already infected with human papillomavirus (HPV) serotypes 16 and 18 is well tolerated and induces a robust immune response, according to a phase 1 study published in the Oct. 10 issue of Science Translational Medicine.
Hormone Replacement Therapy Initiated Early Deemed Safe
WEDNESDAY, Oct. 10 (HealthDay News) -- For women who receive hormone replacement therapy soon after menopause, long-term cardiovascular outcomes are good, with no increase in the risk of any cancer, according to a study published online Oct. 9 in BMJ.
Review Compares Effectiveness of Tocolytic Agents
WEDNESDAY, Oct. 10 (HealthDay News) -- The most effective tocolytic agents for delaying delivery and improving neonatal and maternal outcomes are prostaglandin inhibitors and calcium channel blockers, according to a meta-analysis published online Oct. 9 in BMJ.
Proneurotensin Linked to Increased Disease, Death Risk
TUESDAY, Oct. 9 (HealthDay News) -- Plasma levels of proneurotensin are associated with the future development of diabetes, cardiovascular disease, and cardiovascular and total mortality, as well as breast cancer in women, according to a study published in the Oct. 10 issue of the Journal of the American Medical Association.
Mathematical Model Can Help Predict Chances of Conception
TUESDAY, Oct. 9 (HealthDay News) -- A new mathematical model can help predict the chances that a couple will conceive based on how many months they have been trying to conceive, according to a study published online Oct. 4 in PLoS One.
Prenatal Psychotropic Meds Affect Infant Language
MONDAY, Oct. 8 (HealthDay News) -- Maternal mood and exposure to serotonin reuptake inhibitors (SRIs) in pregnancy affect development of the infant speech perception system, according to a study published online Oct. 8 in the Proceedings of the National Academy of Sciences.
ADHD Risk Increased With Maternal Mercury Exposure
MONDAY, Oct. 8 (HealthDay News) -- The risk of developing attention-deficit/hyperactivity disorder (ADHD) is higher with low-level prenatal mercury exposure, but lower with maternal fish consumption during pregnancy, according to a study published online Oct. 8 in the Archives of Pediatrics & Adolescent Medicine.
Free Birth Control Substantially Lowers Abortion Rate
MONDAY, Oct. 8 (HealthDay News) -- Providing no-cost birth control, including long-acting reversible contraceptives (LARCs) such as intrauterine devices or implants, substantially reduces abortion rates and teenage pregnancies compared with the national rate, according to research published online Oct. 3 in Obstetrics & Gynecology.
Gene Variant Linked to Uterine Fibroid Risk
MONDAY, Oct. 8 (HealthDay News) -- A variant of a gene involved in fatty acid synthesis that is often overproduced in cancers is associated with a higher risk of developing uterine fibroids, according to research published in the Oct. 5 issue of the American Journal of Human Genetics.
Bisphenol A Linked to Thyroid Changes During Pregnancy
FRIDAY, Oct. 5 (HealthDay News) -- Maternal exposure to bisphenol A (BPA) during pregnancy is related to reduced free thyroxine (T4) in the mother and lower thyroid-stimulating hormone (TSH) in male neonates, according to research published online Oct. 4 in Environmental Health Perspectives.
Predictors of Breast Cancer Locoregional Recurrence ID'd
THURSDAY, Oct. 4 (HealthDay News) -- In breast cancer patients treated with neoadjuvant chemotherapy (NC), independent predictors of locoregional recurrence (LRR) can be used to identify LRR risk, according to research published online Oct. 1 in the Journal of Clinical Oncology.
Sexual Abuse May Affect Cervical Cancer Screening Rates
THURSDAY, Oct. 4 (HealthDay News) -- Women who have experienced sexual abuse as children or young adults are less likely to attend regular cervical cancer screenings, according to research published online in the October issue of the Journal of Family Planning & Reproductive Health Care.
Hypertension in Pregnancy May Affect Offspring's Cognition
WEDNESDAY, Oct. 3 (HealthDay News) -- Men born of mothers who were hypertensive in pregnancy have lower cognitive abilities and greater cognitive decline in old age, according to a study published online Oct. 3 in Neurology.
Limiting the Problem of Missing Data Urged for Clinical Trials
WEDNESDAY, Oct. 3 (HealthDay News) -- Missing data compromise inferences from clinical trials, and due to the problematic nature of compensation with analysis methods, the importance of avoiding missing data in clinical trials is paramount, according to a special report published in the Oct. 4 issue of the New England Journal of Medicine.
Fertility Treatment Linked to Multiple Sclerosis Worsening
WEDNESDAY, Oct. 3 (HealthDay News) -- Fertility treatment is associated with a higher risk of multiple sclerosis (MS) exacerbations, which is linked to the increase in reproductive hormones affecting immune function, according to a study published online Oct. 3 in the Annals of Neurology.
Common Herbicide Linked to Rare Birth Defect
TUESDAY, Oct. 2 (HealthDay News) -- Maternal exposure to a common herbicide, atrazine, is associated with a nearly two-fold higher risk of having offspring with a rare birth defect of the nasal cavity, according to a study published online Sept. 28 in The Journal of Pediatrics.
Digital Mammography Tops Screen-Film for Screening
TUESDAY, Oct. 2 (HealthDay News) -- Compared with screen-film mammography, digital mammography substantially improved the detection of ductal carcinoma in situ (DCIS) and invasive carcinoma, particularly when associated with microcalcifications, without an increase in clinically insignificant lesions, according to a study published online Oct. 2 in Radiology.
No New Safety Concerns for Gardasil in Young Females
TUESDAY, Oct. 2 (HealthDay News) -- Since its approval in 2006, no new safety concerns have been found to be associated with vaccinating girls and young women with the quadrivalent human papillomavirus vaccine (HPV4), Gardasil, according to a study published online Oct. 1 in the Archives of Pediatrics & Adolescent Medicine.
Observation Units Could Save $3.1 Billion Nationally Per Year
TUESDAY, Oct. 2 (HealthDay News) -- The addition of observation units to U.S. hospitals which do not currently have them in place could save $3.1 billion nationally per year in health care costs, according to a study published online Sept. 26 in Health Affairs.
Pregnancy-Onset Snoring Linked to High Blood Pressure
TUESDAY, Oct. 2 (HealthDay News) -- Pregnancy-onset snoring is associated with a significantly increased risk of gestational hypertension and preeclampsia, according to research published online Sept. 10 in the American Journal of Obstetrics & Gynecology.
Sexual Dysfunction Common With Aromatase Inhibitors
MONDAY, Oct. 1 (HealthDay News) -- Sexual dysfunction is common among postmenopausal women treated with aromatase inhibitors after breast cancer, according to a study published online Sept. 17 in Menopause.
Patients Benefit From Access to Physician Notes
MONDAY, Oct. 1 (HealthDay News) -- Patients report clinically relevant benefits and minimal concerns, while doctors do not experience negative consequences, from allowing patient access to visit notes, according to a study published in the Oct. 1 issue of the Annals of Internal Medicine.
Developmental Outcomes Good for Late Preterm Infants in NICU
MONDAY, Oct. 1 (HealthDay News) -- Late preterm infants (LPIs), born at 34 to 36 weeks of gestation, who receive intensive care, have similar cognitive, motor, and language skills at age 3 as LPIs who did not receive intensive care, according to a study published online Oct. 1 in Pediatrics.
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