Here are what the editors at HealthDay consider to be the most important developments in Pulmonology for October 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
U.S. Medicare Spending on Elderly Has Outpaced Canada's
TUESDAY, Oct. 30 (HealthDay News) -- U.S. Medicare spending on the elderly has grown nearly three times faster than its Canadian counterpart, according to a study published online Oct. 29 in the Archives of Internal Medicine.
Smoke-Free Laws Linked to Fewer Hospital Admissions
MONDAY, Oct. 29 (HealthDay News) -- Comprehensive smoke-free legislation is associated with decreases in hospital admissions for cardiovascular and respiratory disease, according to a meta-analysis published in the Oct. 30 issue of Circulation.
Sleep Apnea Linked to Less Severe Injury During Acute MI
THURSDAY, Oct. 25 (HealthDay News) -- During an acute non-fatal myocardial infarction (MI), patients with obstructive sleep apnea (OSA) have less severe cardiac injury, according to a study published in the October issue of Sleep and Breathing.
Better Outcomes for Ventilation With Lower Tidal Volumes
TUESDAY, Oct. 23 (HealthDay News) -- Protective ventilation with lower tidal volumes is associated with better clinical outcomes in patients without acute respiratory distress syndrome (ARDS), according to a meta-analysis published in the Oct. 24 issue of the Journal of the American Medical Association.
Genuine Very Large Effects in Trials Rare in Medicine
TUESDAY, Oct. 23 (HealthDay News) -- Large treatment effects are most likely to be found in small studies, with the effect diminishing with additional trials, according to research published in the Oct. 24 issue of the Journal of the American Medical Association.
House Dust Protein Worsens Allergic Asthma
FRIDAY, Oct. 19 (HealthDay News) -- A bacterial protein found in house dust can promote the development of allergic asthma in response to indoor allergens, according to a letter published online Oct. 14 in Nature Medicine.
Return to Work Difficult for Doctors on Sick Leave
THURSDAY, Oct. 18 (HealthDay News) -- Returning to work after a prolonged sick leave for physical or mental health problems, or drug or alcohol problems, is difficult for doctors, who describe self-stigmatization and fear a negative response on their return to work, according to a study published online Oct. 15 in BMJ Open.
Treating Obstructive Sleep Apnea Tied to Lasting BP Drop
THURSDAY, Oct. 18 (HealthDay News) -- In men with obstructive sleep apnea (OSA) and preexisting systemic hypertension or type 2 diabetes, positive airway pressure (PAP) is associated with a significant and sustained reduction in both systolic and diastolic blood pressure (BP), according to research published in the Oct. 15 issue of the Journal of Clinical Sleep Medicine.
Linezolid Beneficial in Drug-Resistant Tuberculosis
THURSDAY, Oct. 18 (HealthDay News) -- Adding linezolid to ongoing background therapy for the treatment of extensively drug-resistant (XDR) pulmonary tuberculosis is effective in achieving culture conversion, but patients must be carefully monitored for adverse events, according to research published in the Oct. 18 issue of the New England Journal of Medicine.
Direct Link ID'd for Sleep Deprivation, Insulin Sensitivity
TUESDAY, Oct. 16 (HealthDay News) -- Even short-term sleep restriction results in an insulin-resistant state in adipocytes, according to research published in the Oct. 16 issue of the Annals of Internal Medicine.
Decline in Pulmonary Function Leads to Cognitive Decline
THURSDAY, Oct. 11 (HealthDay News) -- For older adults, decreases in pulmonary function lead to subsequent declines in cognitive function, according to a study published in the September issue of Psychological Science.
New Image Analysis Technique Improves COPD Diagnosis
THURSDAY, Oct. 11 (HealthDay News) -- A new voxel-wise image analysis technique, parametric response map (PRM), can be used to diagnose chronic obstructive pulmonary disease (COPD) phenotype and provide information about the extent and location of disease and its progression, according to research published online Oct. 7 in Nature Medicine.
Biomarker Can Help Identify Pleural Mesothelioma
WEDNESDAY, Oct. 10 (HealthDay News) -- Fibulin-3 levels in plasma and lung fluids can discriminate patients with mesothelioma from others with asbestos exposure or those whose lung effusions are unrelated to mesothelioma, according to a study published in the Oct. 11 issue of the New England Journal of Medicine.
Bitter Taste Linked to Response to Respiratory Infections
WEDNESDAY, Oct. 10 (HealthDay News) -- Bitter taste receptors are connected with the ability to detect and respond to gram-negative bacteria such as Pseudomonas aeruginosa in the upper respiratory tract, according to a study published online Oct. 8 in the Journal of Clinical Investigation.
Portable Device Feasible for Donor Lung Preservation
WEDNESDAY, Oct. 10 (HealthDay News) -- Donor lungs can be safely preserved and successfully transplanted with the Organ Care System (OCS) Lung device, according to a pilot study published online Oct. 10 in The Lancet.
Unsuspected PE Seldom Linked to Death in Cancer Patients
TUESDAY, Oct. 9 (HealthDay News) -- Unsuspected pulmonary embolism (UPE) is not associated with an increased risk of death in cancer patients when compared to patients without pulmonary embolism (PE), according to research published in the October issue of the Journal of Thrombosis and Haemostasis.
SNP in Gene Involved in Immunity Tied to Lung Cancer
MONDAY, Oct. 8 (HealthDay News) -- Genomic data suggest that a single nucleotide polymorphism (SNP) in the nuclear factor of kappa light polypeptide gene enhancer of B cells 1 (NFKB1) is associated with lung cancer, with the cytosine-thymine (CT)/TT genotype linked to reduced risk, according to a study published online Oct. 8 in Cancer.
Limiting the Problem of Missing Data Urged for Clinical Trials
WEDNESDAY, Oct. 3 (HealthDay News) -- Missing data compromise inferences from clinical trials, and due to the problematic nature of compensation with analysis methods, the importance of avoiding missing data in clinical trials is paramount, according to a special report published in the Oct. 4 issue of the New England Journal of Medicine.
Observation Units Could Save $3.1 Billion Nationally Per Year
TUESDAY, Oct. 2 (HealthDay News) -- The addition of observation units to U.S. hospitals which do not currently have them in place could save $3.1 billion nationally per year in health care costs, according to a study published online Sept. 26 in Health Affairs.
Patients Benefit From Access to Physician Notes
MONDAY, Oct. 1 (HealthDay News) -- Patients report clinically relevant benefits and minimal concerns, while doctors do not experience negative consequences, from allowing patient access to visit notes, according to a study published in the Oct. 1 issue of the Annals of Internal Medicine.
Melatonin Effective for Sleep in Patients Taking β-Blockers
MONDAY, Oct. 1 (HealthDay News) -- Patients taking β-blockers for hypertension, which can disturb sleep, have improved sleep quality with melatonin treatment, according to a study published in the Oct. 1 issue of SLEEP.
Respiratory Virus Patterns ID'd for Urban, Suburban Infants
MONDAY, Oct. 1 (HealthDay News) -- Compared with babies living in more suburban locations, those living in inner-city areas tend to have different patterns of viral respiratory illness, according to a study published online Sept. 25 in the Journal of Infectious Diseases.
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